Calorie restriction-induced SIRT6 activation delays aging by suppressing NF-κB signaling

scientific article published on 03 March 2016

Calorie restriction-induced SIRT6 activation delays aging by suppressing NF-κB signaling is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1080/15384101.2016.1152427
P932PMC publication ID4889297
P698PubMed publication ID26940461

P2093author name stringWei Mu
Zhao Wang
Ying Qiu
Liyuan Li
Zhuoran Wang
Nannan Zhang
Yaru Liang
Maoyang Lu
Zhongchi Li
P2860cites workHuman SIRT6 promotes DNA end resection through CtIP deacetylationQ24299287
SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatinQ24310658
SIRT6 links histone H3 lysine 9 deacetylation to NF-kappaB-dependent gene expression and organismal life spanQ24315083
Sir2 mediates longevity in the fly through a pathway related to calorie restrictionQ24560016
A biomarker that identifies senescent human cells in culture and in aging skin in vivoQ24562644
SIRT6 overexpression induces massive apoptosis in cancer cells but not in normal cellsQ24626021
Caloric restriction delays disease onset and mortality in rhesus monkeysQ24655994
Motif module map reveals enforcement of aging by continual NF-kappaB activityQ24680880
Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiaeQ27933365
Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteinsQ28139564
The sirtuin SIRT6 regulates lifespan in male miceQ28260687
Mouse Sir2 homolog SIRT6 is a nuclear ADP-ribosyltransferaseQ28505800
Genomic instability and aging-like phenotype in the absence of mammalian SIRT6Q28509079
Ink4a/Arf expression is a biomarker of agingQ28570483
The histone deacetylase Sirt6 regulates glucose homeostasis via Hif1alphaQ28588941
SIRT6 promotes DNA repair under stress by activating PARP1Q33803766
Histone acetyltransferases are crucial regulators in NF-κB mediated inflammation.Q33866592
Histological changes in the kidneys of experimental diabetic rats fed with Momordica charantia (bitter gourd) extractQ34021429
The regulation of INK4/ARF in cancer and agingQ34575801
The sirtuin SIRT6 blocks IGF-Akt signaling and development of cardiac hypertrophy by targeting c-JunQ35458082
Global analyses revealed age-related alterations in innate immune responses after stimulation of pathogen recognition receptorsQ35527203
Interventions to Slow Aging in Humans: Are We Ready?Q35935123
The journey of resveratrol from yeast to humanQ35947372
Energy excess is the main cause of accelerated aging of mammalsQ35955149
Calorie restriction, SIRT1 and metabolism: understanding longevityQ36071224
Glucose restriction inhibits skeletal myoblast differentiation by activating SIRT1 through AMPK-mediated regulation of NamptQ36728127
The molecular biology of mammalian SIRT proteins: SIRT2 in cell cycle regulationQ36800817
Activation of innate immunity system during aging: NF-kB signaling is the molecular culprit of inflamm-agingQ36982964
SIRT3 overexpression antagonizes high glucose accelerated cellular senescence in human diploid fibroblasts via the SIRT3-FOXO1 signaling pathwayQ37300592
Sirtuins, aging, and metabolismQ37960472
Immune system, cell senescence, aging and longevity--inflamm-aging reappraisedQ38099327
Serum from calorie-restricted animals delays senescence and extends the lifespan of normal human fibroblasts in vitro.Q38889552
The importance of the p50 NF-κB subunitQ41257779
The transformative promise of aging scienceQ42357394
Linking calorie restriction to longevity through sirtuins and autophagy: any role for TOR.Q42588116
Beneficial effect of Bupleurum polysaccharides on autoimmune disease induced by Campylobacter jejuni in BALB/c mice.Q45997832
SnapShot: sirtuins, NAD, and aging.Q46871443
NF-kappaB signaling in the aging processQ47598860
Hayflick, his limit, and cellular ageingQ48774640
Liver cancer initiation is controlled by AP-1 through SIRT6-dependent inhibition of survivin.Q54288930
The Cell Cycle: A ReviewQ57405732
The bicinchoninic acid (BCA) assay for protein quantitationQ72783075
Morphometric study of arterioles and glomeruli in the aging kidney suggests focal loss of autoregulationQ73111464
SIRT6 regulates osteogenic differentiation of rat bone marrow mesenchymal stem cells partially via suppressing the nuclear factor-κB signaling pathwayQ87259676
P4510describes a project that usesImageJQ1659584
P433issue7
P921main subjectNF-κBQ411114
P1104number of pages10
P304page(s)1009-1018
P577publication date2016-03-03
P1433published inCell CycleQ1254166
P1476titleCalorie restriction-induced SIRT6 activation delays aging by suppressing NF-κB signaling
P478volume15

Reverse relations

cites work (P2860)
Q90701571CTRP3 ameliorates cerulein-induced severe acute pancreatitis in mice via SIRT1/NF-κB/p53 axis
Q58735435Mechanisms of the anti-aging and prolongevity effects of caloric restriction: evidence from studies of genetically modified animals
Q64067884Obesity May Accelerate the Aging Process
Q38665115SIRT1 and SIRT6 Signaling Pathways in Cardiovascular Disease Protection
Q90255200SIRT6 deacetylase activity regulates NAMPT activity and NAD(P)(H) pools in cancer cells
Q37423517SIRT6 delays cellular senescence by promoting p27Kip1 ubiquitin-proteasome degradation.
Q94073889Sirtuins in Renal Health and Disease
Q38930264Sirtuins, a promising target in slowing down the ageing process.
Q39036066The role of caloric load and mitochondrial homeostasis in the regulation of the NLRP3 inflammasome

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