Epigenetic regulation of the INK4b-ARF-INK4a locus: in sickness and in health

scientific article

Epigenetic regulation of the INK4b-ARF-INK4a locus: in sickness and in health is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.4161/EPI.5.8.12996
P3181OpenCitations bibliographic resource ID4844215
P932PMC publication ID3052884
P698PubMed publication ID20716961
P5875ResearchGate publication ID45694990

P50authorJesus GilQ55472013
P2093author name stringNikolay Popov
P2860cites workChromosome 9p21 SNPs Associated with Multiple Disease Phenotypes Correlate with ANRIL ExpressionQ21092443
INK4/ARF transcript expression is associated with chromosome 9p21 variants linked to atherosclerosisQ21562488
Bypass of senescence by the polycomb group protein CBX8 through direct binding to the INK4A-ARF locusQ24298715
The Polycomb group protein EZH2 directly controls DNA methylationQ24299020
Polycomb group and SCF ubiquitin ligases are found in a novel BCOR complex that is recruited to BCL6 targetsQ24301123
Role of histone H2A ubiquitination in Polycomb silencingQ24305090
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controlsQ24550675
Rnf2 (Ring1b) deficiency causes gastrulation arrest and cell cycle inhibitionQ24554110
Molecular interplay of the noncoding RNA ANRIL and methylated histone H3 lysine 27 by polycomb CBX7 in transcriptional silencing of INK4aQ24633736
A common allele on chromosome 9 associated with coronary heart diseaseQ24647989
Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expressionQ24654249
Epigenetic silencing of tumour suppressor gene p15 by its antisense RNAQ24655224
Histone demethylase JMJD3 contributes to epigenetic control of INK4a/ARF by oncogenic RASQ24657459
The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cellsQ24680814
CDK inhibitors: positive and negative regulators of G1-phase progressionQ27860983
A common variant of the p16(INK4a) genetic region is associated with physical function in older peopleQ36136695
Regulation of the INK4b-ARF-INK4a tumour suppressor locus: all for one or one for all.Q36572080
SWI/SNF mediates polycomb eviction and epigenetic reprogramming of the INK4b-ARF-INK4a locusQ36710858
Gene silencing by DNA methylation in haematological malignanciesQ36816162
Members of a family of JmjC domain-containing oncoproteins immortalize embryonic fibroblasts via a JmjC domain-dependent processQ36882963
Cancer and ageing: convergent and divergent mechanismsQ36918634
Polycomb CBX7 promotes initiation of heritable repression of genes frequently silenced with cancer-specific DNA hypermethylationQ37426642
Polycomb group proteins: navigators of lineage pathways led astray in cancerQ37620148
Signatures of mutation and selection in the cancer genomeQ39737975
Transcription factor YY1 functions as a PcG protein in vivoQ39738160
p15Ink4b is a critical tumour suppressor in the absence of p16Ink4aQ40090783
P16INK4a is required for hSNF5 chromatin remodeler-induced cellular senescence in malignant rhabdoid tumor cellsQ40618783
A region of the human HOXD cluster that confers polycomb-group responsivenessQ42067778
A Polycomb group protein complex with sequence-specific DNA-binding and selective methyl-lysine-binding activitiesQ42424377
The Drosophila Polycomb group gene pleiohomeotic encodes a DNA binding protein with homology to the transcription factor YY1.Q47071388
Expression of the p16INK4a tumor suppressor versus other INK4 family members during mouse development and aging.Q52526599
Distinct patterns of inactivation of p15INK4B and p16INK4A characterize the major types of hematological malignanciesQ63641308
Immunohistochemical survey of p16INK4A expression in normal human adult and infant tissuesQ73017608
An INKlination for epigenetic control of senescenceQ79790429
Role of histone H3 lysine 27 methylation in Polycomb-group silencingQ28131795
Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammalsQ28131802
Polycomb CBX7 has a unifying role in cellular lifespanQ28188425
Opposing effects of Ets and Id proteins on p16INK4a expression during cellular senescenceQ28203134
The H3K27me3 demethylase JMJD3 contributes to the activation of the INK4A-ARF locus in response to oncogene- and stress-induced senescenceQ28245403
Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancersQ28251857
A cell cycle regulator potentially involved in genesis of many tumor typesQ28251933
Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrestQ28270478
MAPKAP kinase 3pK phosphorylates and regulates chromatin association of the polycomb group protein Bmi1Q28295095
The H3K36 demethylase Jhdm1b/Kdm2b regulates cell proliferation and senescence through p15(Ink4b)Q28296070
Posterior transformation, neurological abnormalities, and severe hematopoietic defects in mice with a targeted deletion of the bmi-1 proto-oncogeneQ28505536
Ink4a and Arf differentially affect cell proliferation and neural stem cell self-renewal in Bmi1-deficient miceQ28511962
Ink4a/Arf expression is a biomarker of agingQ28570483
Mouse polycomb proteins bind differentially to methylated histone H3 and RNA and are enriched in facultative heterochromatinQ28587001
Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetesQ28680760
A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variantsQ29547210
Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levelsQ29547214
The landscape of somatic copy-number alteration across human cancersQ29547648
A common variant on chromosome 9p21 affects the risk of myocardial infarctionQ29614954
Histone methyltransferase activity of a Drosophila Polycomb group repressor complexQ29615394
Drosophila enhancer of Zeste/ESC complexes have a histone H3 methyltransferase activity that marks chromosomal Polycomb sitesQ29615395
The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locusQ29619815
Nucleolar Arf sequesters Mdm2 and activates p53Q29620244
Epigenetic stem cell signature in cancerQ29622897
Polycomb-mediated methylation on Lys27 of histone H3 pre-marks genes for de novo methylation in cancerQ29622925
A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencingQ33268624
Linkage and association study of late-onset Alzheimer disease families linked to 9p21.3.Q33652208
Pc-G/trx-G and the SWI/SNF connection: developmental gene regulation through chromatin remodelingQ33855686
Short RNAs are transcribed from repressed polycomb target genes and interact with polycomb repressive complex-2.Q33914791
Tissue-specific p19Arf regulation dictates the response to oncogenic K-rasQ33933332
Targeted deletion of the 9p21 non-coding coronary artery disease risk interval in miceQ34121996
Tumor suppressor gene identification using retroviral insertional mutagenesis in Blm-deficient miceQ34549869
The regulation of INK4/ARF in cancer and agingQ34575801
Characterization of a germ-line deletion, including the entire INK4/ARF locus, in a melanoma-neural system tumor family: identification of ANRIL, an antisense noncoding RNA whose expression coclusters with ARF.Q34619960
JHDM1B/FBXL10 is a nucleolar protein that represses transcription of ribosomal RNA genesQ34712349
Ndy1/KDM2B immortalizes mouse embryonic fibroblasts by repressing the Ink4a/Arf locusQ34940029
Frequent p16-independent inactivation of p14ARF in human melanomaQ35541602
P433issue8
P407language of work or nameEnglishQ1860
P304page(s)685-690
P577publication date2010-11-01
P1433published inEpigeneticsQ15753739
P1476titleEpigenetic regulation of the INK4b-ARF-INK4a locus: in sickness and in health
P478volume5

Reverse relations

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