| scholarly article | Q13442814 |
| P50 | author | Ronald A. DePinho | Q7364619 |
| Lynda Chin | Q16207911 | ||
| Alexei Protopopov | Q125308347 | ||
| Kristin L Forloney | Q125312224 | ||
| Harry T Jenq | Q125312322 | ||
| Cameron Brennan | Q30502649 | ||
| P2093 | author name string | Alexander H Stegh | |
| Janina P Luciano | |||
| John A Mahoney | |||
| P2860 | cites work | Role of the INK4a locus in tumor suppression and cell mortality. | Q53455197 |
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| Epidermal growth factor receptor and Ink4a/Arf | Q57277079 | ||
| p63 and p73 are required for p53-dependent apoptosis in response to DNA damage | Q59065672 | ||
| Induction of bax by genotoxic stress in human cells correlates with normal p53 status and apoptosis | Q62746078 | ||
| WAF1/CIP1 is induced in p53-mediated G1 arrest and apoptosis | Q72269510 | ||
| A role for ATR in the DNA damage-induced phosphorylation of p53 | Q22008733 | ||
| PUMA, a novel proapoptotic gene, is induced by p53 | Q24291463 | ||
| ASPP proteins specifically stimulate the apoptotic function of p53 | Q24291844 | ||
| p53 has a direct apoptogenic role at the mitochondria | Q24298888 | ||
| Differential contribution of Puma and Noxa in dual regulation of p53-mediated apoptotic pathways | Q24306130 | ||
| Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis | Q24307994 | ||
| Bad, a heterodimeric partner for Bcl-XL and Bcl-2, displaces Bax and promotes cell death | Q24311298 | ||
| Stimulation of p53-mediated transcriptional activation by the p53-binding proteins, 53BP1 and 53BP2 | Q24316208 | ||
| ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways | Q24321528 | ||
| PUMA couples the nuclear and cytoplasmic proapoptotic function of p53 | Q24321694 | ||
| Mdm2 promotes the rapid degradation of p53 | Q24322597 | ||
| Interaction between the retinoblastoma protein and the oncoprotein MDM2 | Q24323385 | ||
| Gadd45, a p53-responsive stress protein, modifies DNA accessibility on damaged chromatin | Q24554531 | ||
| MDMX: a novel p53-binding protein with some functional properties of MDM2 | Q24561971 | ||
| Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1 | Q24651548 | ||
| Comprehensive genomic characterization defines human glioblastoma genes and core pathways | Q24656128 | ||
| Bcl2L12 inhibits post-mitochondrial apoptosis signaling in glioblastoma | Q24670606 | ||
| Regulation of p53 stability by Mdm2 | Q27860744 | ||
| WAF1, a potential mediator of p53 tumor suppression | Q27861121 | ||
| Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis | Q28144256 | ||
| p53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa | Q28204059 | ||
| Puma is an essential mediator of p53-dependent and -independent apoptotic pathways | Q28213279 | ||
| Mutual dependence of MDM2 and MDMX in their functional inactivation of p53 | Q28214705 | ||
| Tumor suppressor p53 is a regulator of bcl-2 and bax gene expression in vitro and in vivo | Q28253554 | ||
| Analysis of the mammalian gadd45 gene and its response to DNA damage | Q28255848 | ||
| Divorcing ARF and p53: an unsettled case | Q28258356 | ||
| The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53 | Q28266637 | ||
| Amplification of a gene encoding a p53-associated protein in human sarcomas | Q28270924 | ||
| Tumor suppressor p53 is a direct transcriptional activator of the human bax gene | Q28306186 | ||
| A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia | Q29615437 | ||
| Regulating the p53 pathway: in vitro hypotheses, in vivo veritas | Q29615658 | ||
| The p53 pathway: positive and negative feedback loops | Q29617535 | ||
| Malignant astrocytic glioma: genetics, biology, and paths to treatment | Q29618156 | ||
| Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms | Q29618586 | ||
| Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF | Q29619663 | ||
| ATM associates with and phosphorylates p53: mapping the region of interaction | Q30175960 | ||
| Defining the p53 DNA-binding domain/Bcl-x(L)-binding interface using NMR. | Q33198227 | ||
| p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation | Q33733341 | ||
| Regulation of p53 stability | Q33807793 | ||
| The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2. | Q33889383 | ||
| Requirement of ATM in phosphorylation of the human p53 protein at serine 15 following DNA double-strand breaks | Q33957738 | ||
| The p53MH algorithm and its application in detecting p53-responsive genes | Q34064408 | ||
| Mitochondrial p53 activates Bak and causes disruption of a Bak-Mcl1 complex. | Q34312488 | ||
| Stimulation of E2F1/DP1 transcriptional activity by MDM2 oncoprotein | Q34313966 | ||
| The molecular and genetic basis of neurological tumours | Q34770308 | ||
| DNA damage induces phosphorylation of the amino terminus of p53 | Q35199554 | ||
| The pCL vector system: rapid production of helper-free, high-titer, recombinant retroviruses | Q35866801 | ||
| Intrinsic tumour suppression | Q35953133 | ||
| Drug resistance of human glioblastoma cells conferred by a tumor-specific mutant epidermal growth factor receptor through modulation of Bcl-XL and caspase-3-like proteases | Q36097402 | ||
| HdmX stimulates Hdm2-mediated ubiquitination and degradation of p53. | Q36347917 | ||
| The P53 pathway: what questions remain to be explored? | Q36430168 | ||
| Bcl2L12-mediated inhibition of effector caspase-3 and caspase-7 via distinct mechanisms in glioblastoma | Q36825199 | ||
| Living with p53, dying of p53. | Q36919156 | ||
| Molecular pathology of malignant gliomas | Q37014747 | ||
| The p53-cathepsin axis cooperates with ROS to activate programmed necrotic death upon DNA damage | Q37079047 | ||
| The mitochondrial p53 pathway | Q37325095 | ||
| Pten haploinsufficiency accelerates formation of high-grade astrocytomas | Q37384874 | ||
| The multiple levels of regulation by p53 ubiquitination | Q37526379 | ||
| Bad is a BH3 domain-containing protein that forms an inactivating dimer with Bcl-XL. | Q40024055 | ||
| Staurosporine-induced apoptosis is independent of p16 and p21 and achieved via arrest at G2/M and at G1 in U251MG human glioma cell line | Q40651329 | ||
| Differential induction of transcriptionally active p53 following UV or ionizing radiation: defects in chromosome instability syndromes? | Q41513765 | ||
| Germ-line transmission of a mutated p53 gene in a cancer-prone family with Li-Fraumeni syndrome | Q41816411 | ||
| Malignant astrocytomas originate from neural stem/progenitor cells in a somatic tumor suppressor mouse model | Q43170042 | ||
| Genetic pathways to glioblastoma: a population-based study | Q44673208 | ||
| Amplification and overexpression of the MDM2 gene in a subset of human malignant gliomas without p53 mutations. | Q48115514 | ||
| What drives intense apoptosis resistance and propensity for necrosis in glioblastoma? A role for Bcl2L12 as a multifunctional cell death regulator | Q48939992 | ||
| P433 | issue | 19 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | Transformation related protein 53 | Q14818136 |
| BCL2 like 12 | Q21100303 | ||
| P304 | page(s) | 2194-204 | |
| P577 | publication date | 2010-10-01 | |
| P1433 | published in | Genes & Development | Q1524533 |
| P1476 | title | Glioma oncoprotein Bcl2L12 inhibits the p53 tumor suppressor | |
| P478 | volume | 24 |
| Q99549233 | A Glance of p53 Functions in Brain Development, Neural Stem Cells, and Brain Cancer |
| Q35547227 | A computational approach to identifying gene-microRNA modules in cancer |
| Q64084930 | Alkylaminophenol Induces G1/S Phase Cell Cycle Arrest in Glioblastoma Cells Through p53 and Cyclin-Dependent Kinase Signaling Pathway |
| Q34699520 | BCL2L12 is a novel biomarker for the prediction of short-term relapse in nasopharyngeal carcinoma |
| Q34621019 | Beyond effector caspase inhibition: Bcl2L12 neutralizes p53 signaling in glioblastoma |
| Q59790175 | Celastrus orbiculatus extracts induce apoptosis in mTOR-overexpressed human hepatocellular carcinoma HepG2 cells |
| Q39147197 | Cisplatin downregulates BCL2L12, a novel apoptosis-related gene, in glioblastoma cells. |
| Q55271166 | Codelivery of temozolomide and siRNA with polymeric nanocarrier for effective glioma treatment. |
| Q38112074 | Current understanding of the role and targeting of tumor suppressor p53 in glioblastoma multiforme |
| Q39136321 | Effect of doxorubicin, oxaliplatin, and methotrexate administration on the transcriptional activity of BCL-2 family gene members in stomach cancer cells |
| Q37382513 | Estrogen receptor β isoform 5 confers sensitivity of breast cancer cell lines to chemotherapeutic agent-induced apoptosis through interaction with Bcl2L12. |
| Q54110692 | GSK3β‑mediated Ser156 phosphorylation modulates a BH3‑like domain in BCL2L12 during TMZ‑induced apoptosis and autophagy in glioma cells. |
| Q26829086 | Gene therapy for brain tumors: basic developments and clinical implementation |
| Q59809213 | Global, Survival, and Apoptotic Transcriptome during Mouse and Human Early Embryonic Development |
| Q38626416 | How to train glioma cells to die: molecular challenges in cell death |
| Q36954204 | Identification of key genes in glioblastoma-associated stromal cells using bioinformatics analysis |
| Q46972532 | Increased BCL2L12 expression predicts the short-term relapse of patients with TaT1 bladder cancer following transurethral resection of bladder tumors |
| Q52147098 | Integrated analysis identified genes associated with a favorable prognosis in oligodendrogliomas. |
| Q41630032 | Integrins and p53 pathways in glioblastoma resistance to temozolomide |
| Q36591548 | Long Noncoding RNA LOC100129973 Suppresses Apoptosis by Targeting miR-4707-5p and miR-4767 in Vascular Endothelial Cells. |
| Q47292301 | Micellar formulations of Crizotinib and Dasatinib in the management of glioblastoma multiforme. |
| Q37986129 | MicroRNA-181a - a tale of discrepancies |
| Q37826349 | Novel Perspectives on p53 Function in Neural Stem Cells and Brain Tumors |
| Q38828893 | Protease-activated receptor-2 suppresses interleukin (IL)-10 expression in B cells via upregulating Bcl2L12 in patients with allergic rhinitis |
| Q90401877 | Proteinase-activated receptor-2 enhances Bcl2-like protein-12 expression in lung cancer cells to suppress p53 expression |
| Q50494309 | Quantitative expression analysis of the apoptosis-related gene, BCL2L12, in head and neck squamous cell carcinoma |
| Q39413532 | Quantitative expression analysis of the apoptosis-related genes BCL2, BAX and BCL2L12 in gastric adenocarcinoma cells following treatment with the anticancer drugs cisplatin, etoposide and taxol |
| Q39352683 | Radioresistance of human glioma spheroids and expression of HSP70, p53 and EGFr |
| Q53827532 | Revisiting the role of IRF3 in inflammation and immunity by conditional and specifically targeted gene ablation in mice. |
| Q30577878 | Spherical nucleic acid nanoparticle conjugates as an RNAi-based therapy for glioblastoma |
| Q42405739 | Spherical nucleic acids for precision medicine |
| Q47635874 | Stress Hormone Cortisol Enhances Bcl2 Like-12 Expression to Inhibit p53 in Hepatocellular Carcinoma Cells. |
| Q35929525 | Studying a complex tumor: potential and pitfalls |
| Q35795073 | Targeting the p53 signaling pathway in cancer therapy - the promises, challenges and perils |
| Q35066321 | The Cancer Genome Atlas (TCGA): an immeasurable source of knowledge |
| Q51605255 | The novel function of CD82 and its impact on BCL2L12 via AKT/STAT5 signal pathway in acute myelogenous leukemia cells. |
| Q35584788 | The novel member of the BCL2 gene family, BCL2L12, is substantially elevated in chronic lymphocytic leukemia patients, supporting its value as a significant biomarker |
| Q26851645 | The role of Bcl-2 family proteins in therapy responses of malignant astrocytic gliomas: Bcl2L12 and beyond |
| Q38431547 | Therapeutic applications of spherical nucleic acids |
| Q39000759 | Tumor necrosis factor suppresses interleukin 10 in peripheral B cells via upregulating Bcl2-like protein 12 in patients with inflammatory bowel disease |
| Q37104104 | Whole-genome sequencing identifies a recurrent functional synonymous mutation in melanoma |
| Q35293772 | miR-182 integrates apoptosis, growth, and differentiation programs in glioblastoma |
| Q42034071 | p53 in the CNS: Perspectives on Development, Stem Cells, and Cancer |
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