Characterization of a nuclear export signal within the human T cell leukemia virus type I transactivator protein Tax.

scientific article published on April 2003

Characterization of a nuclear export signal within the human T cell leukemia virus type I transactivator protein Tax. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M211576200
P8608Fatcat IDrelease_wtprfdxi2bcj7ju2zi7d7i3ajq
P698PubMed publication ID12670929

P2093author name stringBrian Wigdahl
Christian Grant
Kate Barmak
Timothy Alefantis
Edward W Harhaj
P2860cites workCalreticulin Is a receptor for nuclear exportQ24290720
Human T cell leukemia virus type 1 Tax associates with a molecular chaperone complex containing hTid-1 and Hsp70Q24291927
Human T cell leukemia virus type 1 oncoprotein Tax targets the human mitotic checkpoint protein MAD1Q24336250
A masked NES in INI1/hSNF5 mediates hCRM1-dependent nuclear export: implications for tumorigenesisQ24536149
Histone deacetylase 4 possesses intrinsic nuclear import and export signalsQ24550857
Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a cysteine residue in the central conserved regionQ24685870
CRM1 is an export receptor for leucine-rich nuclear export signalsQ27860453
Exportin 1 (Crm1p) is an essential nuclear export factorQ27939696
The HIV-1 Rev activation domain is a nuclear export signal that accesses an export pathway used by specific cellular RNAsQ28131708
Leptomycin B inhibition of signal-mediated nuclear export by direct binding to CRM1Q28277890
Identification of a signal for rapid export of proteins from the nucleusQ29547742
CRM1 is responsible for intracellular transport mediated by the nuclear export signalQ29547861
Control of I kappa B-alpha proteolysis by site-specific, signal-induced phosphorylationQ29614709
Leptomycin B is an inhibitor of nuclear export: inhibition of nucleo-cytoplasmic translocation of the human immunodeficiency virus type 1 (HIV-1) Rev protein and Rev-dependent mRNAQ29620175
Evidence for a role of CRM1 in signal-mediated nuclear protein exportQ29620231
Human T-cell leukemia virus type 1 Tax shuttles between functionally discrete subcellular targetsQ30304677
A cytosolic activity distinct from crm1 mediates nuclear export of protein kinase inhibitor in permeabilized cells.Q30454343
Human T-cell leukemia virus type 1 Tax requires direct access to DNA for recruitment of CREB binding protein to the viral promoterQ33770682
Transformation to continuous growth of primary human T lymphocytes by human T-cell leukemia virus type I X-region genes transduced by a Herpesvirus saimiri vectorQ33854474
Nucleocytoplasmic shuttling of transcription factorsQ34058505
Human T cell leukemia virus type I and neurologic disease: events in bone marrow, peripheral blood, and central nervous system during normal immune surveillance and neuroinflammationQ34504487
Human T cell leukemia virus type I-induced disease: pathways to cancer and neurodegenerationQ35111367
Anchoring of CREB binding protein to the human T-cell leukemia virus type 1 promoter: a molecular mechanism of Tax transactivationQ36571545
Human T-cell lymphotropic virus type I (HTLV-I) transcriptional activator, Tax, enhances CREB binding to HTLV-I 21-base-pair repeats by protein-protein interactionQ37135126
Complex NF-kappaB interactions at the distal tumor necrosis factor promoter region in human monocytes.Q38334644
Human T-cell leukemia virus type I Tax transactivates the matrix metalloproteinase-9 gene: potential role in mediating adult T-cell leukemia invasivenessQ39269086
Nucleotide sequence analysis of HTLV-I isolated from cerebrospinal fluid of a patient with TSP/HAM: comparison to other HTLV-I isolatesQ39279523
Limited sequence variation in human T-lymphotropic virus type 1 isolates from North American and African patientsQ39333864
Astrocytic alterations induced by HTLV type 1-infected T lymphocytes: a role for Tax-1 and tumor necrosis factor alphaQ39503113
Identification of p53 sequence elements that are required for MDM2-mediated nuclear exportQ39529269
Prevalent loss of mitotic spindle checkpoint in adult T-cell leukemia confers resistance to microtubule inhibitorsQ40765650
Functional changes in astrocytes by human T-lymphotropic virus type-1 T-lymphocytesQ40784058
Differential usage of nuclear export sequences regulates intracellular localization of the dioxin (aryl hydrocarbon) receptorQ40788306
A human T-cell leukemia virus Tax variant incapable of activating NF-kappaB retains its immortalizing potential for primary T-lymphocytesQ41050877
Identification of HTLV-I tax trans-activator mutants exhibiting novel transcriptional phenotypesQ41715443
Nucleotide sequence analysis of isolates of human T-lymphotropic virus type 1 of diverse geographical originsQ42618776
Differential Tax expression in HTLV type I-infected asymptomatic carriers.Q42686447
Characterization of a novel nuclear localization signal in the HTLV-I tax transactivator proteinQ44798682
IKKgamma serves as a docking subunit of the IkappaB kinase (IKK) and mediates interaction of IKK with the human T-cell leukemia virus Tax proteinQ45747947
Role of Adapter Function in Oncoprotein-mediated Activation of NF-κBQ56567036
P433issue24
P407language of work or nameEnglishQ1860
P921main subjectleukemiaQ29496
P304page(s)21814-21822
P577publication date2003-04-01
P1433published inJournal of Biological ChemistryQ867727
P1476titleCharacterization of a nuclear export signal within the human T cell leukemia virus type I transactivator protein Tax.
P478volume278

Reverse relations

cites work (P2860)
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