Human T-cell leukemia virus type 1 Tax shuttles between functionally discrete subcellular targets

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Human T-cell leukemia virus type 1 Tax shuttles between functionally discrete subcellular targets is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/JVI.74.5.2351-2364.2000
P932PMC publication ID111717
P698PubMed publication ID10666266

P2093author name stringT J Hope
B Maier
M Burton
C D Upadhyaya
O J Semmes
P2860cites workHuman T cell leukemia virus type 1 oncoprotein Tax targets the human mitotic checkpoint protein MAD1Q24336250
Trans-activation of the human immunodeficiency virus long terminal repeat sequence by DNA virusesQ24627466
Mutational analysis of the conserved basic domain of human immunodeficiency virus tat proteinQ24656004
Nuclear-cytoplasmic shuttling of C-ABL tyrosine kinaseQ28591266
The HIV-1 Rev trans-activator shuttles between the nucleus and the cytoplasmQ28646841
The dynamics of a pre-mRNA splicing factor in living cellsQ29617746
Macromolecular domains within the cell nucleusQ29618685
HTLV-I trans-activator protein, tax, is a trans-repressor of the human beta-polymerase geneQ41740897
Nuclear export of cyclin B1 and its possible role in the DNA damage-induced G2 checkpointQ41828411
Molecular interactions between the coactivator CBP and the human T-cell leukemia virus Tax proteinQ45754350
Nuclear export signal of IkappaBalpha interferes with the Rev-dependent posttranscriptional regulation of human immunodeficiency virus type I.Q45758597
Recognition of bZIP proteins by the human T-cell leukaemia virus transactivator Tax.Q45787620
HTLV-I Tax protein binds to MEKK1 to stimulate IkappaB kinase activity and NF-kappaB activationQ47964174
The x gene is essential for HTLV replicationQ48377207
Control of cAMP-regulated enhancers by the viral transactivator Tax through CREB and the co-activator CBP.Q55240568
HTLV-1 oncoprotein Tax deregulates transcription of cellular genes through multiple mechanisms.Q55240878
The pX protein of HTLV-I is a transcriptional activator of its long terminal repeats.Q55244921
Visualization of replication factories attached to nucleoskeletonQ72216658
The cellular organization of gene expressionQ74701351
Mechanism of DNA-binding enhancement by the human T-cell leukaemia virus transactivator Tax.Q30417542
Mta has properties of an RNA export protein and increases cytoplasmic accumulation of Epstein-Barr virus replication gene mRNA.Q30453521
c-fos promoter trans-activation by the tax1 protein of human T-cell leukemia virus type IQ33670763
An exposed KID-like domain in human T-cell lymphotropic virus type 1 Tax is responsible for the recruitment of coactivators CBP/p300Q33777090
Human T-cell leukemia virus type 1 Tax induction of NF-kappaB involves activation of the IkappaB kinase alpha (IKKalpha) and IKKbeta cellular kinasesQ33777633
Modulation of Sp1 phosphorylation by human immunodeficiency virus type 1 Tat.Q33782959
Cytoplasmic forms of human T-cell leukemia virus type 1 Tax induce NF-kappaB activationQ33783624
Nuclear export of the E1B 55-kDa and E4 34-kDa adenoviral oncoproteins mediated by a rev-like signal sequenceQ33887076
Nucleo-cytoplasmic shuttling of the hdm2 oncoprotein regulates the levels of the p53 protein via a pathway used by the human immunodeficiency virus rev protein.Q33888123
Differential transcriptional activation by human T-cell leukemia virus type 1 Tax mutants is mediated by distinct interactions with CREB binding protein and p300Q33996796
Trans-acting transcriptional regulation of human T-cell leukemia virus type III long terminal repeatQ34563887
Mechanisms of human T-cell leukemia virus-induced leukemogenesisQ35236463
The human T-cell leukemia virus (HTLV) transactivator (Tax) proteinQ35360202
Adenovirus early region 4 34-kilodalton protein directs the nuclear localization of the early region 1B 55-kilodalton protein in primate cells.Q35868511
Localization of human T-cell leukemia virus type 1 tax to subnuclear compartments that overlap with interchromatin specklesQ35868564
Human T-cell leukemia virus type I Tax-protein-mediated activation of NF-kappa B from p100 (NF-kappa B2)-inhibited cytoplasmic reservoirsQ35995731
Serine phosphorylation of SR proteins is required for their recruitment to sites of transcription in vivoQ36255596
Pleiotropic effect of the human T-cell leukemia virus Tax protein on the DNA binding activity of eukaryotic transcription factorsQ36461344
Anchoring of CREB binding protein to the human T-cell leukemia virus type 1 promoter: a molecular mechanism of Tax transactivationQ36571545
Mutational analysis of human T-cell leukemia virus type I Tax: regions necessary for function determined with 47 mutant proteinsQ36687133
DNA and RNA within the nucleus: How much sequence-specific spatial organization?Q36706293
Identification of p40x-responsive regulatory sequences within the human T-cell leukemia virus type I long terminal repeatQ36889867
Molecular biology of the type I human T-cell leukemia virus (HTLV-I) and adult T-cell leukemiaQ37648645
Human T-cell leukemia virus type I Tax protein represses gene expression through the basic helix-loop-helix family of transcription factors.Q38304467
Overproduction of NFKB2 (lyt-10) and c-Rel: a mechanism for HTLV-I Tax-mediated trans-activation via the NF-kappa B signalling pathway.Q38310694
A trans-activator Tax of human T-cell leukemia virus type 1 binds to NF-kappa B p50 and serum response factor (SRF) and associates with enhancer DNAs of the NF-kappa B site and CArG box.Q38316421
Interaction of HTLV-1 Tax1 with p67SRF causes the aberrant induction of cellular immediate early genes through CArG boxesQ38324803
The human T-cell leukemia virus type 1 oncoprotein Tax inhibits the transcriptional activity of c-Myb through competition for the CREB binding protein.Q39582339
Serum response factor has functional roles both in indirect binding to the CArG box and in the transcriptional activation function of human T-cell leukemia virus type I Tax.Q40042426
Effects of a highly basic region of human immunodeficiency virus Tat protein on nucleolar localizationQ40108559
Probing Functional Organization within the Nucleus: Is Genome Structure Integrated with RNA Metabolism?Q40394206
Organization of (pre-)mRNA metabolism in the cell nucleusQ40506141
A novel regulatory mechanism in the mitogen-activated protein (MAP) kinase cascade. Role of nuclear export signal of MAP kinase kinase.Q41070272
Molecular biology of HTLV-I: recent progressQ41106108
Repression of bax gene expression by the HTLV-1 Tax protein: implications for suppression of apoptosis in virally infected cellsQ41114974
HTLV-1 21 bp repeat sequences facilitate stable association between Tax and CREB to increase CREB binding affinityQ41150263
Human T-cell leukemia virus type I tax masks c-Myc function through a cAMP-dependent pathwayQ41204966
HTLV-I and HTLV-II Tax: differences in induction of micronuclei in cells and transcriptional activation of viral LTRsQ41225869
Transcriptional repression of p53 by human T-cell leukemia virus type I Tax proteinQ41267676
HTLV-1 Tax enhances NF-kappa B2 expression and binds to the products p52 and p100, but does not suppress the inhibitory function of p100.Q41372549
Human T-cell leukemia virus type I Tax associates with and is negatively regulated by the NF-kappa B2 p100 gene product: implications for viral latencyQ41489682
P433issue5
P921main subjectleukemiaQ29496
Human T-lymphotropic virus 1Q1280388
T-cell leukemiaQ7667895
P304page(s)2351-2364
P577publication date2000-03-01
P1433published inJournal of VirologyQ1251128
P1476titleHuman T-cell leukemia virus type 1 Tax shuttles between functionally discrete subcellular targets
P478volume74

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cites work (P2860)
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Q34132731An RNA interference screen identifies the Deubiquitinase STAMBPL1 as a critical regulator of human T-cell leukemia virus type 1 tax nuclear export and NF-κB activation
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Q37336808HSP90 protects the human T-cell leukemia virus type 1 (HTLV-1) tax oncoprotein from proteasomal degradation to support NF-κB activation and HTLV-1 replication
Q35749018HTLV-1 Tax Stimulates Ubiquitin E3 Ligase, Ring Finger Protein 8, to Assemble Lysine 63-Linked Polyubiquitin Chains for TAK1 and IKK Activation.
Q52591266HTLV-1 Tax is a critical lipid raft modulator that hijacks IkappaB kinases to the microdomains for persistent activation of NF-kappaB.
Q24291927Human T cell leukemia virus type 1 Tax associates with a molecular chaperone complex containing hTid-1 and Hsp70
Q41881538Human T cell leukemia virus type 2 tax-mediated NF-κB activation involves a mechanism independent of Tax conjugation to ubiquitin and SUMO.
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Q45443442Human T-lymphotropic virus, type 1, tax protein triggers microtubule reorientation in the virological synapse
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Q28257025Life, death, and tax: role of HTLV-I oncoprotein in genetic instability and cellular transformation
Q41895077PDZ binding motif of HTLV-1 Tax promotes virus-mediated T-cell proliferation in vitro and persistence in vivo
Q34278817Physical interaction of human T-cell leukemia virus type 1 Tax with cyclin-dependent kinase 4 stimulates the phosphorylation of retinoblastoma protein
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Q38262353Regulation of HTLV-1 tax stability, cellular trafficking and NF-κB activation by the ubiquitin-proteasome pathway
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Q38867996Secretion of the human T cell leukemia virus type I transactivator protein tax.
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Q34314933Visualizing spatiotemporal dynamics of apoptosis after G1 arrest by human T cell leukemia virus type 1 Tax and insights into gene expression changes using microarray-based gene expression analysis

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