Secretion of the human T cell leukemia virus type I transactivator protein tax.

scientific article published on 19 January 2005

Secretion of the human T cell leukemia virus type I transactivator protein tax. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M409851200
P698PubMed publication ID15659397

P2093author name stringPooja Jain
Brian Wigdahl
Christian Grant
Timothy Alefantis
Edward Harhaj
Kate Mostoller
P2860cites workHuman T cell leukemia virus type 1 Tax associates with a molecular chaperone complex containing hTid-1 and Hsp70Q24291927
Human T-cell lymphotropic virus type 1-infected T lymphocytes impair catabolism and uptake of glutamate by astrocytes via Tax-1 and tumor necrosis factor alphaQ24525274
HIV-1 Tat protein exits from cells via a leaderless secretory pathway and binds to extracellular matrix-associated heparan sulfate proteoglycans through its basic regionQ28252310
Control of I kappa B-alpha proteolysis by site-specific, signal-induced phosphorylationQ29614709
Human T-cell leukemia virus type 1 Tax shuttles between functionally discrete subcellular targetsQ30304677
Human T-cell leukemia virus type 1 Tax requires direct access to DNA for recruitment of CREB binding protein to the viral promoterQ33770682
Human T cell lymphotropic virus type I genomic expression and impact on intracellular signaling pathways during neurodegenerative disease and leukemiaQ33854078
Human T-lymphotropic virus type 1 oncoprotein tax promotes S-phase entry but blocks mitosisQ34336234
Human T cell leukemia virus type I and neurologic disease: events in bone marrow, peripheral blood, and central nervous system during normal immune surveillance and neuroinflammationQ34504487
Efficient export of the vesicular stomatitis virus G protein from the endoplasmic reticulum requires a signal in the cytoplasmic tail that includes both tyrosine-based and di-acidic motifsQ34664121
Human T cell leukemia virus type I-induced disease: pathways to cancer and neurodegenerationQ35111367
Mediators of central nervous system damage during the progression of human T-cell leukemia type I-associated myelopathy/tropical spastic paraparesisQ35226367
Anchoring of CREB binding protein to the human T-cell leukemia virus type 1 promoter: a molecular mechanism of Tax transactivationQ36571545
Human T-cell lymphotropic virus type I (HTLV-I) transcriptional activator, Tax, enhances CREB binding to HTLV-I 21-base-pair repeats by protein-protein interactionQ37135126
Interaction of the human T-cell lymphotrophic virus type I (HTLV-I) transcriptional activator Tax with cellular factors that bind specifically to the 21-base-pair repeats in the HTLV-I enhancerQ37649857
Characterization of a nuclear export signal within the human T cell leukemia virus type I transactivator protein Tax.Q38867998
Extracellular human T-cell lymphotropic virus type I Tax protein induces cytokine production in adult human microglial cellsQ38971953
Increased HTLV type 1 tax specific CD8+ cells in HTLV type 1-asociated myelopathy/tropical spastic paraparesis: correlation with HTLV type 1 proviral loadQ39149916
Cross-reactivity between immunodominant human T lymphotropic virus type I tax and neurons: implications for molecular mimicryQ39173024
Autoimmunity due to molecular mimicry as a cause of neurological diseaseQ39173031
Astrocytic alterations induced by HTLV type 1-infected T lymphocytes: a role for Tax-1 and tumor necrosis factor alphaQ39503113
Expression of a biologically active antiviral antibody using a sindbis virus vector systemQ41095095
Construction of stable BHK-21 cells coexpressing human secretory glycoproteins and human Gal(beta 1-4)GlcNAc-R alpha 2,6-sialyltransferase alpha 2,6-linked NeuAc is preferentially attached to the Gal(beta 1-4)GlcNAc(beta 1-2)Man(alpha 1-3)-branch ofQ41295222
Tartrate-resistant acid phosphatase: gene structure and functionQ41320757
Post-Golgi membrane traffic: brefeldin A inhibits export from distal Golgi compartments to the cell surface but not recyclingQ41614909
A di-acidic (DXE) code directs concentration of cargo during export from the endoplasmic reticulumQ41666503
Identification of HTLV-I tax trans-activator mutants exhibiting novel transcriptional phenotypesQ41715443
Characterization of a novel nuclear localization signal in the HTLV-I tax transactivator proteinQ44798682
IKKgamma serves as a docking subunit of the IkappaB kinase (IKK) and mediates interaction of IKK with the human T-cell leukemia virus Tax proteinQ45747947
A regulated secretory pathway in cultured hippocampal astrocytes.Q48148441
Role of Adapter Function in Oncoprotein-mediated Activation of NF-κBQ56567036
P433issue17
P407language of work or nameEnglishQ1860
P921main subjectleukemiaQ29496
P304page(s)17353-17362
P577publication date2005-01-19
P1433published inJournal of Biological ChemistryQ867727
P1476titleSecretion of the human T cell leukemia virus type I transactivator protein tax.
P478volume280

Reverse relations

cites work (P2860)
Q34132731An RNA interference screen identifies the Deubiquitinase STAMBPL1 as a critical regulator of human T-cell leukemia virus type 1 tax nuclear export and NF-κB activation
Q39392791Comparison of the Genetic Organization, Expression Strategies and Oncogenic Potential of HTLV-1 and HTLV-2.
Q30276544Exosomes in Viral Disease
Q35238447GCN5 inhibits XBP-1S-mediated transcription by antagonizing PCAF action
Q44433562HIV-1 Tat is unconventionally secreted through the plasma membrane
Q36434903HTLV tax: a fascinating multifunctional co-regulator of viral and cellular pathways
Q38718353HTLV-1 Tax activates HIV-1 transcription in latency models
Q34717839Induction of lactoferrin gene expression in myeloid or mammary gland cells by human T-cell leukemia virus type 1 (HTLV-1) tax: implications for milk-borne transmission of HTLV-1.
Q39207637Inhibition of cyclin-dependent kinase 5 but not of glycogen synthase kinase 3-β prevents neurite retraction and tau hyperphosphorylation caused by secretable products of human T-cell leukemia virus type I-infected lymphocytes.
Q30442529Interaction of HTLV-1 Tax protein with calreticulin: implications for Tax nuclear export and secretion
Q47154454Interference of HTLV-1 Tax Protein with Cell Polarity Regulators: Defining the Subcellular Localization of the Tax-DLG1 Interaction
Q37945226Intracellular localization and cellular factors interaction of HTLV-1 and HTLV-2 Tax proteins: similarities and functional differences.
Q64120396MEF-2 isoforms' (A-D) roles in development and tumorigenesis
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Q33753132Molecular Mechanisms of Neurodegenerative Diseases Induced by Human Retroviruses: A Review
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Q64093299Neuroimmunology of Human T-Lymphotropic Virus Type 1-Associated Myelopathy/Tropical Spastic Paraparesis
Q41888962PCAF interacts with XBP-1S and mediates XBP-1S-dependent transcription
Q38262353Regulation of HTLV-1 tax stability, cellular trafficking and NF-κB activation by the ubiquitin-proteasome pathway
Q56333817Role of Exosomes in Human Retroviral Mediated Disorders
Q37336150Role of resident CNS cell populations in HTLV-1-associated neuroinflammatory disease
Q38623545Tax posttranslational modifications and interaction with calreticulin in MT-2 cells and human peripheral blood mononuclear cells of human T cell lymphotropic virus type-I-associated myelopathy/tropical spastic paraparesis patients
Q39239834Tax secretion from peripheral blood mononuclear cells and Tax detection in plasma of patients with human T-lymphotropic virus-type 1-associated myelopathy/tropical spastic paraparesis and asymptomatic carriers
Q30353061Tax-1 and Tax-2 similarities and differences: focus on post-translational modifications and NF-κB activation.
Q21093224The HTLV-1 Tax interactome
Q38615502The HTLV-1 Virological Synapse.
Q34219706The ins and outs of HIV-1 Tat.
Q46853154The intricate interplay between RNA viruses and NF-κB.
Q45406469The nuclear import of the human T lymphotropic virus type I (HTLV-1) tax protein is carrier- and energy-independent
Q36447062Ubiquitination of HTLV-I Tax in response to DNA damage regulates nuclear complex formation and nuclear export
Q40086144Up-regulation of hepatitis C virus replication by human T cell leukemia virus type I-encoded Tax protein
Q38864131Use of human antigen presenting cell gene array profiling to examine the effect of human T-cell leukemia virus type 1 Tax on primary human dendritic cells
Q56333946Viral antigens detectable in CSF exosomes from patients with retrovirus associated neurologic disease: functional role of exosomes
Q36540100XBP-1, a novel human T-lymphotropic virus type 1 (HTLV-1) tax binding protein, activates HTLV-1 basal and tax-activated transcription

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