Is there a role for ubiquitin or SUMO in human T-cell leukemia virus type 2 Tax-induced NF-κB activation?

scientific article published on March 2013

Is there a role for ubiquitin or SUMO in human T-cell leukemia virus type 2 Tax-induced NF-κB activation? is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.2217/FVL.13.1
P932PMC publication ID3665948
P698PubMed publication ID23730325

P2093author name stringAlfonso Lavorgna
Edward W Harhaj
P2860cites workNeuroimmunity of HTLV-I InfectionQ37741036
Regulation of NF-κB by deubiquitinasesQ37995682
Identification of a novel motif responsible for the distinctive transforming activity of human T-cell leukemia virus (HTLV) type 1 Tax1 protein from HTLV-2 Tax2.Q39798425
Cooperation of NF-kappaB2/p100 activation and the PDZ domain binding motif signal in human T-cell leukemia virus type 1 (HTLV-1) Tax1 but not HTLV-2 Tax2 is crucial for interleukin-2-independent growth transformation of a T-cell lineQ40090310
Activation of NF-kappa B by the human T cell leukemia virus type I Tax oncoprotein is associated with ubiquitin-dependent relocalization of I kappa B kinaseQ40201021
A 10-amino acid domain within human T-cell leukemia virus type 1 and type 2 tax protein sequences is responsible for their divergent subcellular distributionQ40532741
Human T cell leukemia virus type 2 tax-mediated NF-κB activation involves a mechanism independent of Tax conjugation to ubiquitin and SUMO.Q41881538
PDZ binding motif of HTLV-1 Tax promotes virus-mediated T-cell proliferation in vitro and persistence in vivoQ41895077
Hostile takeovers: viral appropriation of the NF-kB pathwayQ22241900
The kinase IKKα inhibits activation of the transcription factor NF-κB by phosphorylating the regulatory molecule TAX1BP1Q24315115
Comparative biology of human T-cell lymphotropic virus type 1 (HTLV-1) and HTLV-2Q24653987
NF-κB, the first quarter-century: remarkable progress and outstanding questionsQ26822516
Human T-cell leukemia virus type 1 Tax shuttles between functionally discrete subcellular targetsQ30304677
Tax oncoprotein of HTLV-1 binds to the human homologue of Drosophila discs large tumor suppressor protein, hDLG, and perturbs its function in cell growth controlQ30810844
HTLV-I Tax-dependent and -independent events associated with immortalization of human primary T lymphocytesQ33754639
An RNA interference screen identifies the Deubiquitinase STAMBPL1 as a critical regulator of human T-cell leukemia virus type 1 tax nuclear export and NF-κB activationQ34132731
Exclusive ubiquitination and sumoylation on overlapping lysine residues mediate NF-kappaB activation by the human T-cell leukemia virus tax oncoproteinQ34150778
Natural history of adult T-cell leukemia/lymphoma and approaches to therapyQ34450097
Role of post-translational modifications of HTLV-1 Tax in NF-κB activationQ34878458
Ubiquitin-specific peptidase 20 targets TRAF6 and human T cell leukemia virus type 1 tax to negatively regulate NF-kappaB signalingQ35077552
Human T Lymphotropic Virus Type 1 (HTLV-1): Molecular Biology and OncogenesisQ35261245
The Sumo-targeted ubiquitin ligase RNF4 regulates the localization and function of the HTLV-1 oncoprotein Tax.Q35750342
Distinct transformation tropism exhibited by human T lymphotropic virus type 1 (HTLV-1) and HTLV-2 is the result of postinfection T cell clonal expansionQ35826764
Activation of NF-kappaB by HTLV-I and implications for cell transformationQ36254865
HTLV-2 Tax immortalizes human CD4+ memory T lymphocytes by oncogenic activation and dysregulation of autophagyQ36298491
The human T-cell leukemia virus type 1 Tax oncoprotein requires the ubiquitin-conjugating enzyme Ubc13 for NF-kappaB activationQ36315236
Ubiquitination and sumoylation of the HTLV-2 Tax-2B protein regulate its NF-κB activity: a comparative study with the HTLV-1 Tax-1 proteinQ36526768
PDLIM2 suppresses human T-cell leukemia virus type I Tax-mediated tumorigenesis by targeting Tax into the nuclear matrix for proteasomal degradationQ37176572
P433issue3
P921main subjectNF-κBQ411114
T-cell leukemiaQ7667895
P304page(s)223-227
P577publication date2013-03-01
P1433published inFuture VirologyQ15751230
P1476titleIs there a role for ubiquitin or SUMO in human T-cell leukemia virus type 2 Tax-induced NF-κB activation?
P478volume8

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