Nuclear RNA export pathways.

scientific article

Nuclear RNA export pathways. is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P356DOI10.1128/MCB.20.12.4181-4187.2000
P932PMC publication ID85787
P698PubMed publication ID10825183

P2093author name stringB R Cullen
P2860cites workRAE1 is a shuttling mRNA export factor that binds to a GLEBS-like NUP98 motif at the nuclear pore complex through multiple domainsQ22009429
Processing of intervening sequences: a new yeast mutant which fails to excise intervening sequences from precursor tRNAsQ71156037
The human tap nuclear RNA export factor contains a novel transportin-dependent nuclear localization signal that lacks nuclear export signal functionQ73133774
Definition of a consensus transportin-specific nucleocytoplasmic transport signalQ74638201
Dbp5, a DEAD-box protein required for mRNA export, is recruited to the cytoplasmic fibrils of nuclear pore complex via a conserved interaction with CAN/Nup159pQ22010452
Transport between the cell nucleus and the cytoplasmQ22065411
A nuclear export signal in hnRNP A1: a signal-mediated, temperature-dependent nuclear protein export pathwayQ24309825
Catalysis of guanine nucleotide exchange on Ran by the mitotic regulator RCC1Q24311327
Transportin-mediated nuclear import of heterogeneous nuclear RNP proteinsQ24312051
Identification of a tRNA-specific nuclear export receptorQ24314506
mRNA binding protein mrnp 41 localizes to both nucleus and cytoplasmQ24322800
A cap-binding protein complex mediating U snRNA exportQ24336104
Inhibition of human immunodeficiency virus Rev and human T-cell leukemia virus Rex function, but not Mason-Pfizer monkey virus constitutive transport element activity, by a mutant human nucleoporin targeted to Crm1Q24523655
The role of exportin-t in selective nuclear export of mature tRNAsQ24533485
TAP binds to the constitutive transport element (CTE) through a novel RNA-binding motif that is sufficient to promote CTE-dependent RNA export from the nucleusQ24534064
The Mex67p-mediated nuclear mRNA export pathway is conserved from yeast to humanQ24534127
The C-terminal domain of TAP interacts with the nuclear pore complex and promotes export of specific CTE-bearing RNA substratesQ24539652
Identification of different roles for RanGDP and RanGTP in nuclear protein importQ24561933
RanGAP1 induces GTPase activity of nuclear Ras-related RanQ24564044
Amphibian transcription factor IIIA proteins contain a sequence element functionally equivalent to the nuclear export signal of human immunodeficiency virus type 1 RevQ24568152
CRM1 is an export receptor for leucine-rich nuclear export signalsQ27860453
Nuclear export of the small ribosomal subunit requires the ran-GTPase cycle and certain nucleoporins.Q27931933
GLE2, a Saccharomyces cerevisiae homologue of the Schizosaccharomyces pombe export factor RAE1, is required for nuclear pore complex structure and functionQ27933501
The yeast nucleoporin rip1p contributes to multiple export pathways with no essential role for its FG-repeat region.Q27934181
Dbp5p, a cytosolic RNA helicase, is required for poly(A)+ RNA exportQ27934203
Nuclear mRNA export requires complex formation between Mex67p and Mtr2p at the nuclear pores.Q27934517
Dbp5p/Rat8p is a yeast nuclear pore-associated DEAD-box protein essential for RNA exportQ27937989
A novel in vivo assay reveals inhibition of ribosomal nuclear export in ran-cycle and nucleoporin mutantsQ27939245
Exportin 1 (Crm1p) is an essential nuclear export factorQ27939696
Mex67p, a novel factor for nuclear mRNA export, binds to both poly(A)+ RNA and nuclear poresQ27940054
The human RAE1 gene is a functional homologue of Schizosaccharomyces pombe rae1 gene involved in nuclear export of Poly(A)+ RNAQ28116098
The HIV-1 Rev activation domain is a nuclear export signal that accesses an export pathway used by specific cellular RNAsQ28131708
Nucleocytoplasmic transport: the soluble phaseQ28131723
Protein import into nuclei: association and dissociation reactions involving transport substrate, transport factors, and nucleoporinsQ28131733
The nuclear pore complex: from molecular architecture to functional dynamicsQ28138909
The importin-beta family member Crm1p bridges the interaction between Rev and the nuclear pore complex during nuclear exportQ28254641
Identification of a nuclear export receptor for tRNAQ28265348
TAP, the human homolog of Mex67p, mediates CTE-dependent RNA export from the nucleusQ28276214
The HIV-1 rev trans-activator acts through a structured target sequence to activate nuclear export of unspliced viral mRNAQ28279502
The human Tap protein is a nuclear mRNA export factor that contains novel RNA-binding and nucleocytoplasmic transport sequencesQ28646657
HIV-1 structural gene expression requires the binding of multiple Rev monomers to the viral RRE: implications for HIV-1 latencyQ28646762
Evidence that HIV-1 Rev directly promotes the nuclear export of unspliced RNAQ28646843
Identification of a signal for rapid export of proteins from the nucleusQ29547742
CRM1 is responsible for intracellular transport mediated by the nuclear export signalQ29547861
The asymmetric distribution of the constituents of the Ran system is essential for transport into and out of the nucleusQ29616325
Nuclear export of different classes of RNA is mediated by specific factorsQ29618449
Shuttling of pre-mRNA binding proteins between nucleus and cytoplasmQ29618907
Transport of proteins and RNAs in and out of the nucleusQ29619554
The GTP-binding protein Ran/TC4 is required for protein import into the nucleusQ29620192
Evidence for a role of CRM1 in signal-mediated nuclear protein exportQ29620231
The constitutive transport element (CTE) of Mason-Pfizer monkey virus (MPMV) accesses a cellular mRNA export pathwayQ30448360
A small element from the Mason-Pfizer monkey virus genome makes human immunodeficiency virus type 1 expression and replication Rev-independentQ30454030
Leptomycin B inhibits equine infectious anemia virus Rev and feline immunodeficiency virus rev function but not the function of the hepatitis B virus posttranscriptional regulatory elementQ33784046
The K nuclear shuttling domain: a novel signal for nuclear import and nuclear export in the hnRNP K proteinQ33886877
A second post-transcriptional trans-activator gene required for HTLV-III replicationQ34162178
The hnRNP C proteins contain a nuclear retention sequence that can override nuclear export signalsQ36237427
Nuclear tRNA aminoacylation and its role in nuclear export of endogenous tRNAs in Saccharomyces cerevisiaeQ36745203
Splicing is required for rapid and efficient mRNA export in metazoansQ36776804
tRNA transport from the nucleus in a eukaryotic cell: carrier-mediated translocation processQ37512771
The arginine-rich domains present in human immunodeficiency virus type 1 Tat and Rev function as direct importin beta-dependent nuclear localization signalsQ39610897
A functional homologue of the RNA1 gene product in Schizosaccharomyces pombe: purification, biochemical characterization, and identification of a leucine-rich repeat motifQ40365606
A look at messenger RNP moving through the nuclear poreQ41367422
RNA transportQ41369752
Facilitated nuclear transport of histone H1 and other small nucleophilic proteinsQ41740214
Regulation by HIV Rev depends upon recognition of splice sitesQ41758926
Coordination of tRNA nuclear export with processing of tRNA.Q41845245
The NES-Crm1p export pathway is not a major mRNA export route in Saccharomyces cerevisiaeQ42676980
The simian retrovirus-1 constitutive transport element, unlike the HIV-1 RRE, uses factors required for cellular mRNA exportQ44103395
Retroviruses as model systems for the study of nuclear RNA export pathwaysQ45345414
A pre-mRNA-binding protein accompanies the RNA from the gene through the nuclear pores and into polysomesQ48066850
Proofreading and aminoacylation of tRNAs before export from the nucleus.Q50741048
Monomethylated cap structures facilitate RNA export from the nucleus.Q50804073
Intranuclear location of the tRNA splicing enzymesQ57385024
Functional dissection of the HIV-1 Rev trans-activator—Derivation of a trans-dominant repressor of Rev functionQ58611466
Some cis- and trans-acting mutants for splicing target pre-mRNA to the cytoplasmQ69502444
P433issue12
P407language of work or nameEnglishQ1860
P304page(s)4181-4187
P577publication date2000-06-01
P1433published inMolecular and Cellular BiologyQ3319478
P1476titleNuclear RNA export pathways.
P478volume20

Reverse relations

cites work (P2860)
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Q34354274A new view of mRNA export: separating the wheat from the chaff
Q24683176A nuclear kinesin-like protein interacts with and stimulates the activity of the leucine-rich nuclear export signal of the human immunodeficiency virus type 1 rev protein
Q24675650An essential role for hGle1 nucleocytoplasmic shuttling in mRNA export
Q39775287Analysis of bovine foamy virus btas mRNA transcripts during persistent infection
Q34077876Box C/D small nucleolar RNA trafficking involves small nucleolar RNP proteins, nucleolar factors and a novel nuclear domain
Q44030629Cajal body dynamics and association with chromatin are ATP-dependent
Q38302290Control of nuclear export of hnRNP A1.
Q45383937DNA constructs expressing long-hairpin RNA (lhRNA) protect Penaeus monodon against White Spot Syndrome Virus
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Q30493932Diffusion-based transport of nascent ribosomes in the nucleus
Q38212068Dynamic Post-Transcriptional Regulation of HIV-1 Gene Expression
Q34347652Epstein-Barr virus mRNA export factor EB2 is essential for production of infectious virus
Q44638975Evaluating the role of CRM1-mediated export for adenovirus gene expression
Q39586522Evidence for a posttranscriptional role of a TFIIICalpha-like protein in Chironomus tentans
Q24538228Formation of Tap/NXT1 heterodimers activates Tap-dependent nuclear mRNA export by enhancing recruitment to nuclear pore complexes
Q28209036Functional analysis of the interaction of the human immunodeficiency virus type 1 Rev nuclear export signal with its cofactors
Q39683279Genomic but not antigenomic hepatitis delta virus RNA is preferentially exported from the nucleus immediately after synthesis and processing
Q36363829Human CRM1 augments production of infectious human and feline immunodeficiency viruses from murine cells
Q34856375Human immunodeficiency virus type 1 genetic recombination is more frequent than that of Moloney murine leukemia virus despite similar template switching rates
Q42800068Human p32 protein relieves a post-transcriptional block to HIV replication in murine cells
Q24538841ICP27 interacts with the RNA export factor Aly/REF to direct herpes simplex virus type 1 intronless mRNAs to the TAP export pathway
Q34552631ICP27 selectively regulates the cytoplasmic localization of a subset of viral transcripts in herpes simplex virus type 1-infected cells
Q64065729Identification of charged amino acids required for nuclear localization of human L1 ORF1 protein
Q36859268Imaging and characterizing influenza A virus mRNA transport in living cells
Q28215961In vitro analysis of nuclear transport mediated by the C-terminal shuttle domain of Tap
Q24529536Influenza B and C virus NEP (NS2) proteins possess nuclear export activities
Q39601251Interaction of the influenza virus nucleoprotein with the cellular CRM1-mediated nuclear export pathway
Q28587170Members of the tristetraprolin family of tandem CCCH zinc finger proteins exhibit CRM1-dependent nucleocytoplasmic shuttling
Q35786108Minimal introns are not "junk".
Q24674855NXT1 is necessary for the terminal step of Crm1-mediated nuclear export
Q35079139New insights into the nuclear localization of retroviral Gag proteins
Q35241432Nuclear Factor 90, a cellular dsRNA binding protein inhibits the HIV Rev-export function
Q34021302Nuclear entry and CRM1-dependent nuclear export of the Rous sarcoma virus Gag polyprotein.
Q34286048Nuclear export of mRNA.
Q30453281Nuclear interactions are necessary for translational enhancement by spleen necrosis virus RU5.
Q46948332Nucleocytoplasmic transport of fluorescent mRNA in living mammalian cells: nuclear mRNA export is coupled to ongoing gene transcription.
Q33338619PAUSED, a putative exportin-t, acts pleiotropically in Arabidopsis development but is dispensable for viability
Q35920650PSF acts through the human immunodeficiency virus type 1 mRNA instability elements to regulate virus expression
Q59132651Posttranscriptional Regulation of HIV-1 Gene Expression during Replication and Reactivation from Latency by Nuclear Matrix Protein MATR3
Q40196922RNA binding by the herpes simplex virus type 1 nucleocytoplasmic shuttling protein UL47 is mediated by an N-terminal arginine-rich domain that also functions as its nuclear localization signal
Q37997897RNA polymerase II transcription on the fast lane
Q33854295RNA splicing at human immunodeficiency virus type 1 3' splice site A2 is regulated by binding of hnRNP A/B proteins to an exonic splicing silencer element
Q34348421RU5 of Mason-Pfizer monkey virus 5' long terminal repeat enhances cytoplasmic expression of human immunodeficiency virus type 1 gag-pol and nonviral reporter RNA.
Q47965509Rae1-mediated nuclear export of Rnc1 is an important determinant in controlling MAPK signaling.
Q28646696Recruitment of the Crm1 nuclear export factor is sufficient to induce cytoplasmic expression of incompletely spliced human immunodeficiency virus mRNAs
Q34323793Regulation of nuclear gamma interferon gene expression by interleukin 12 (IL-12) and IL-2 represents a novel form of posttranscriptional control
Q39536459Rhesus monkey rhadinovirus ORF57 induces gH and gL glycoprotein expression through posttranscriptional accumulation of target mRNAs
Q34351276Robust growth of human immunodeficiency virus type 1 (HIV-1)
Q36460462Robust suppression of HIV replication by intracellularly expressed reverse transcriptase aptamers is independent of ribozyme processing
Q27640483Structural basis for the interaction between the Tap/NXF1 UBA domain and FG nucleoporins at 1A resolution
Q41836703The Ref/Aly proteins are dispensable for mRNA export and development in Caenorhabditis elegans
Q27637917The crystal structure and mutational analysis of a novel RNA-binding domain found in the human Tap nuclear mRNA export factor
Q33292323The human endogenous retrovirus K Rev response element coincides with a predicted RNA folding region
Q24291654Two closely related human nuclear export factors utilize entirely distinct export pathways
Q28365327Using viral species specificity to define a critical protein/RNA interaction surface
Q27931437Utp8p is an essential intranuclear component of the nuclear tRNA export machinery of Saccharomyces cerevisiae
Q40763108Viral regulation of mRNA export
Q36119000eIF4E is a central node of an RNA regulon that governs cellular proliferation
Q34169710mRNA quality control: Marking the message for life or death.

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