High-content classification of nucleocytoplasmic import or export inhibitors

scientific article published on 16 May 2007

High-content classification of nucleocytoplasmic import or export inhibitors is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1177/1087057107301319
P698PubMed publication ID17507639
P5875ResearchGate publication ID6324111

P50authorAuguste GenovesioQ55114009
P2093author name stringUlf Nehrbass
Hi Chul Kim
Nam Youl Kim
Neil Emans
Yong-Jun Kwon
Brigitte David-Watine
Sungyong Jung
P2860cites workNF-{kappa}B is transported into the nucleus by importin {alpha}3 and importin {alpha}4Q24293000
Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a cysteine residue in the central conserved regionQ24685870
CRM1 is an export receptor for leucine-rich nuclear export signalsQ27860453
Exportin 1 (Crm1p) is an essential nuclear export factorQ27939696
Nucleocytoplasmic transport: the soluble phaseQ28131723
High content screening applied to large-scale cell biologyQ28235592
Leptomycin B inhibition of signal-mediated nuclear export by direct binding to CRM1Q28277890
HIV Rev uses a conserved cellular protein export pathway for the nucleocytoplasmic transport of viral RNAsQ28289718
Identification of a signal for rapid export of proteins from the nucleusQ29547742
Signaling to NF-kappaBQ29547844
CRM1 is responsible for intracellular transport mediated by the nuclear export signalQ29547861
Missing pieces in the NF-kappaB puzzleQ29547864
Rel/NF-kappa B/I kappa B family: intimate tales of association and dissociationQ29615580
NF-kappa B: ten years afterQ29618566
Small-molecule screening and profiling by using automated microscopyQ31132679
Asthma.Q34137112
Autoregulation of I kappa B alpha activityQ34879939
Treatment of allergic airway inflammation and hyperresponsiveness by antisense-induced local blockade of GATA-3 expressionQ36369147
Inducible nuclear expression of newly synthesized I kappa B alpha negatively regulates DNA-binding and transcriptional activities of NF-kappa B.Q36551014
Cytoplasmic sequestration of rel proteins by IkappaBalpha requires CRM1-dependent nuclear exportQ39584943
Nuclear export of cyclin B1 and its possible role in the DNA damage-induced G2 checkpointQ41828411
Role of transcription factors in inflammatory lung diseasesQ43061086
Ratjadone and leptomycin B block CRM1-dependent nuclear export by identical mechanisms.Q45097896
Statistics of assay validation in high throughput cell imaging of nuclear factor kappaB nuclear translocation.Q51959537
Protein kinase C-alpha is an upstream activator of the IkappaB kinase complex in the TPA signal transduction pathway to NF-kappaB in U2OS cells.Q53402600
P433issue5
P304page(s)621-627
P577publication date2007-05-16
P1433published inJournal of Biomolecular ScreeningQ6294856
P1476titleHigh-content classification of nucleocytoplasmic import or export inhibitors
P478volume12

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cites work (P2860)
Q39975500An overview of cell phenotypes in HCS: limitations and advantages
Q38976490Class I and IIa histone deacetylases have opposite effects on sclerostin gene regulation
Q33647302Identification of a small molecule inhibitor of importin β mediated nuclear import by confocal on-bead screening of tagged one-bead one-compound libraries.
Q38066579Moving to the core: spatiotemporal analysis of Forkhead box O (FOXO) and nuclear factor-κB (NF-κB) nuclear translocation
Q33703043Small molecule peptidomimetic inhibitors of importin α/β mediated nuclear transport
Q34398166Targeting nucleocytoplasmic transport in cancer therapy

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