Cytoplasmic localization of Wis1 MAPKK by nuclear export signal is important for nuclear targeting of Spc1/Sty1 MAPK in fission yeast

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Cytoplasmic localization of Wis1 MAPKK by nuclear export signal is important for nuclear targeting of Spc1/Sty1 MAPK in fission yeast is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1091/MBC.02-03-0043
P932PMC publication ID117932
P698PubMed publication ID12181336
P5875ResearchGate publication ID11206708

P2093author name stringKazuhiro Shiozaki
Sasha M Warren
Aaron Ngocky Nguyen
Aminah D Ikner
Mitsue Shiozaki
P2860cites workNuclear localization and regulation of erk- and rsk-encoded protein kinasesQ24606980
CRM1 is an export receptor for leucine-rich nuclear export signalsQ27860453
Activation of yeast PBS2 MAPKK by MAPKKKs or by binding of an SH3-containing osmosensor.Q27930567
Yeast Cdc42 GTPase and Ste20 PAK-like kinase regulate Sho1-dependent activation of the Hog1 MAPK pathway.Q27930943
An osmosensing signal transduction pathway in yeast.Q27932086
Osmotic activation of the HOG MAPK pathway via Ste11p MAPKKK: scaffold role of Pbs2p MAPKK.Q27934994
MAP kinase pathways in yeast: for mating and moreQ27938176
Exportin 1 (Crm1p) is an essential nuclear export factorQ27939696
Eukaryotic proteins expressed in Escherichia coli: An improved thrombin cleavage and purification procedure of fusion proteins with glutathione S-transferaseQ28131695
Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activationQ28131755
Activation of two isoforms of mitogen-activated protein kinase kinase in response to epidermal growth factor and nerve growth factorQ28270919
Improved green fluorescenceQ28307219
A conserved docking site in MEKs mediates high-affinity binding to MAP kinases and cooperates with a scaffold protein to enhance signal transmissionQ28345384
The N-terminal ERK-binding site of MEK1 is required for efficient feedback phosphorylation by ERK2 in vitro and ERK activation in vivoQ28609067
Cytoplasmic localization of the mitogen-activated protein kinase activator MEKQ28609141
Growth factors induce nuclear translocation of MAP kinases (p42mapk and p44mapk) but not of their activator MAP kinase kinase (p45mapkk) in fibroblastsQ28609143
How MAP kinases are regulatedQ28609360
Molecular genetic analysis of fission yeast Schizosaccharomyces pombeQ29547703
Identification of a signal for rapid export of proteins from the nucleusQ29547742
A short amino acid sequence able to specify nuclear locationQ29547781
CRM1 is responsible for intracellular transport mediated by the nuclear export signalQ29547861
Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammationQ29614227
Mitogen-activated protein kinase: conservation of a three-kinase module from yeast to humanQ29618981
Evidence for a role of CRM1 in signal-mediated nuclear protein exportQ29620231
Mitogen-activated protein kinases: specific messages from ubiquitous messengersQ30303652
Phosphorylation and association with the transcription factor Atf1 regulate localization of Spc1/Sty1 stress-activated kinase in fission yeast.Q35200411
Nuclear translocation of mitogen-activated protein kinase kinase (MEK1) in response to mitogenic stimulationQ36105057
Serum-induced translocation of mitogen-activated protein kinase to the cell surface ruffling membrane and the nucleusQ36232666
Activation and regulation of the Spc1 stress-activated protein kinase in Schizosaccharomyces pombeQ36560144
Active nucleocytoplasmic shuttling required for function and regulation of stress-activated kinase Spc1/StyI in fission yeastQ36861198
Heat stress activates fission yeast Spc1/StyI MAPK by a MEKK-independent mechanismQ36873220
Mcs4 mitotic catastrophe suppressor regulates the fission yeast cell cycle through the Wik1-Wis1-Spc1 kinase cascadeQ37385039
The fission yeast mitotic regulator win1+ encodes an MAP kinase kinase kinase that phosphorylates and activates Wis1 MAP kinase kinase in response to high osmolarityQ38612816
Molecular determinants that mediate selective activation of p38 MAP kinase isoformsQ40387373
Transcriptional control by protein phosphorylation: signal transmission from the cell surface to the nucleusQ40427848
Heat-shock-induced activation of stress MAP kinase is regulated by threonine- and tyrosine-specific phosphatases.Q40444385
Glycerol-3-phosphate dehydrogenase homologue from Schizosaccharomyces pombeQ40527126
Transcriptional regulation by extracellular signals: mechanisms and specificityQ40579098
Nuclear export of MAP kinase (ERK) involves a MAP kinase kinase (MEK)-dependent active transport mechanismQ40895714
Two co-existing mechanisms for nuclear import of MAP kinase: passive diffusion of a monomer and active transport of a dimer.Q40925517
Nuclear translocation of p42/p44 mitogen-activated protein kinase is required for growth factor-induced gene expression and cell cycle entryQ40976467
Multiple modes of activation of the stress-responsive MAP kinase pathway in fission yeastQ41006877
The wis1 protein kinase is a dosage-dependent regulator of mitosis in Schizosaccharomyces pombeQ41083893
Interaction of MAP kinase with MAP kinase kinase: its possible role in the control of nucleocytoplasmic transport of MAP kinaseQ41115678
Protein phosphatase 2C, encoded by ptc1+, is important in the heat shock response of Schizosaccharomyces pombeQ42606695
nmt1 of fission yeast. A highly transcribed gene completely repressed by thiamineQ42636951
Stress-activated protein kinase pathway in cell cycle control of fission yeast.Q42661576
Nuclear localization of mitogen-activated protein kinase kinase 1 (MKK1) is promoted by serum stimulation and G2-M progression. Requirement for phosphorylation at the activation lip and signaling downstream of MKK.Q42819066
Cytoplasmic localization of mitogen-activated protein kinase kinase directed by its NH2-terminal, leucine-rich short amino acid sequence, which acts as a nuclear export signalQ45300833
Cell-cycle control linked to extracellular environment by MAP kinase pathway in fission yeast.Q45949013
A conserved motif at the amino termini of MEKs might mediate high-affinity interaction with the cognate MAPKsQ46344054
Conjugation, meiosis, and the osmotic stress response are regulated by Spc1 kinase through Atf1 transcription factor in fission yeastQ46507486
Pyp1 and Pyp2 PTPases dephosphorylate an osmosensing MAP kinase controlling cell size at division in fission yeastQ47348305
The Mcs4 response regulator coordinately controls the stress-activated Wak1-Wis1-Sty1 MAP kinase pathway and fission yeast cell cycle.Q48051117
The use of cell division cycle mutants to investigate the control of microtubule distribution in the fission yeast Schizosaccharomyces pombeQ67980916
Thiamine-repressible expression vectors pREP and pRIP for fission yeastQ70536009
TATA box mutations in the Schizosaccharomyces pombe nmt1 promoter affect transcription efficiency but not the transcription start point or thiamine repressibilityQ70536012
The Atf1 transcription factor is a target for the Sty1 stress-activated MAP kinase pathway in fission yeastQ71574597
Evidence for a novel MAPKKK-independent pathway controlling the stress activated Sty1/Spc1 MAP kinase in fission yeastQ77153475
P433issue8
P407language of work or nameEnglishQ1860
P304page(s)2651-2663
P577publication date2002-08-01
P1433published inMolecular Biology of the CellQ2338259
P1476titleCytoplasmic localization of Wis1 MAPKK by nuclear export signal is important for nuclear targeting of Spc1/Sty1 MAPK in fission yeast
P478volume13

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cites work (P2860)
Q92608964A Redox-Sensitive Thiol in Wis1 Modulates the Fission Yeast Mitogen-Activated Protein Kinase Response to H2O2 and Is the Target of a Small Molecule
Q39790889A docking site determining specificity of Pbs2 MAPKK for Ssk2/Ssk22 MAPKKKs in the yeast HOG pathway
Q52935267Azoles activate Atf1-mediated transcription through MAP kinase pathway for antifungal effects in fission yeast.
Q42252605Biological significance of nuclear localization of mitogen-activated protein kinase Pmk1 in fission yeast
Q41234667Fission yeast MAP kinase Sty1 is recruited to stress-induced genes
Q40884667H₂O₂ stress-specific regulation of S. pombe MAPK Sty1 by mitochondrial protein phosphatase Ptc4.
Q38367073IQGAP1: insights into the function of a molecular puppeteer
Q39791249Identification of Cdc37 as a novel regulator of the stress-responsive mitogen-activated protein kinase
Q35879290Meiotic DNA replication
Q33249032ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe
Q38191702Oxidative stress response pathways: Fission yeast as archetype
Q60138277Protection from Disulfide Stress by Inhibition of Pap1 Nuclear Export in
Q44535713Schizosaccharomyces pombe cells lacking the Ran-binding protein Hba1 show a multidrug resistance phenotype due to constitutive nuclear accumulation of Pap1.
Q42486568Stress-induced response, localization, and regulation of the Pmk1 cell integrity pathway in Schizosaccharomyces pombe
Q41772137Two adjacent docking sites in the yeast Hog1 mitogen-activated protein (MAP) kinase differentially interact with the Pbs2 MAP kinase kinase and the Ptp2 protein tyrosine phosphatase
Q42858911Two-component signaling to the stress MAP kinase cascade in fission yeast.

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