| scholarly article | Q13442814 |
| P50 | author | Gail A Bishop | Q56650269 |
| Ian Catlett | Q73626773 | ||
| P2093 | author name string | B S Hostager | |
| P2860 | cites work | Anatomy of TRAF2. Distinct domains for nuclear factor-kappaB activation and association with tumor necrosis factor signaling proteins | Q24311703 |
| TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways | Q24317441 | ||
| A novel family of putative signal transducers associated with the cytoplasmic domain of the 75 kDa tumor necrosis factor receptor | Q24318280 | ||
| Signaling by proinflammatory cytokines: oligomerization of TRAF2 and TRAF6 is sufficient for JNK and IKK activation and target gene induction via an amino-terminal effector domain | Q24604330 | ||
| TRAF5, a novel tumor necrosis factor receptor-associated factor family protein, mediates CD40 signaling | Q24634187 | ||
| T cell receptor-dependent cell death of T cell hybridomas mediated by the CD30 cytoplasmic domain in association with tumor necrosis factor receptor-associated factors | Q24678367 | ||
| Signal transduction via CD40 involves activation of lyn kinase and phosphatidylinositol-3-kinase, and phosphorylation of phospholipase C gamma 2 | Q24680231 | ||
| Functional rafts in cell membranes | Q27860768 | ||
| RING for destruction? | Q28144245 | ||
| CD27, a member of the tumor necrosis factor receptor superfamily, activates NF-kappaB and stress-activated protein kinase/c-Jun N-terminal kinase via TRAF2, TRAF5, and NF-kappaB-inducing kinase | Q28270530 | ||
| Tumor necrosis factor signaling to stress-activated protein kinase (SAPK)/Jun NH2-terminal kinase (JNK) and p38. Germinal center kinase couples TRAF2 to mitogen-activated protein kinase/ERK kinase kinase 1 and SAPK while receptor interacting [...] | Q28280257 | ||
| ASK1 is essential for JNK/SAPK activation by TRAF2 | Q28285612 | ||
| The involvement of multiple tumor necrosis factor receptor (TNFR)-associated factors in the signaling mechanisms of receptor activator of NF-kappaB, a member of the TNFR superfamily | Q28291317 | ||
| MAP3K-related kinase involved in NF-kappaB induction by TNF, CD95 and IL-1 | Q28302936 | ||
| Identification of TRAF6, a novel tumor necrosis factor receptor-associated factor protein that mediates signaling from an amino-terminal domain of the CD40 cytoplasmic region | Q28511583 | ||
| TRAF2-mediated activation of NF-kappa B by TNF receptor 2 and CD40 | Q28610812 | ||
| Lipid domain structure of the plasma membrane revealed by patching of membrane components | Q29620204 | ||
| CD40 signaling pathway: anti-CD40 monoclonal antibody induces rapid dephosphorylation and phosphorylation of tyrosine-phosphorylated proteins including protein tyrosine kinase Lyn, Fyn, and Syk and the appearance of a 28-kD tyrosine phosphorylated p | Q30442865 | ||
| Engagement of T cell receptor triggers its recruitment to low-density detergent-insoluble membrane domains | Q33889480 | ||
| Haplotype-specific differences in signaling by transfected class II molecules to a Ly-1+ B-cell clone | Q34294743 | ||
| T cell-dependent induction of NF-kappa B in B cells | Q36361506 | ||
| Immune regulation by CD40 and its ligand GP39. | Q41039754 | ||
| Rapid redistribution of CD20 to a low density detergent-insoluble membrane compartment | Q41067716 | ||
| Interaction of influenza virus haemagglutinin with sphingolipid-cholesterol membrane domains via its transmembrane domain | Q41089300 | ||
| Selective activation of c-Jun kinase mitogen-activated protein kinase by CD40 on human B cells | Q41257915 | ||
| Structure of detergent-resistant membrane domains: does phase separation occur in biological membranes? | Q41641699 | ||
| Zinc fingers are sticking together | Q41710093 | ||
| Assembly and regulation of the CD40 receptor complex in human B cells | Q41835791 | ||
| CD40-tumor necrosis factor receptor-associated factor (TRAF) interactions: regulation of CD40 signaling through multiple TRAF binding sites and TRAF hetero-oligomerization | Q42060069 | ||
| T-cell help for cytotoxic T lymphocytes is mediated by CD40-CD40L interactions | Q47982736 | ||
| Help for cytotoxic-T-cell responses is mediated by CD40 signalling | Q47982749 | ||
| TANK, a co-inducer with TRAF2 of TNF- and CD 40L-mediated NF-kappaB activation | Q48064873 | ||
| Characterization of detergent-insoluble complexes containing the cellular prion protein and its scrapie isoform | Q48767220 | ||
| Non-CD28 costimulatory molecules present in T cell rafts induce T cell costimulation by enhancing the association of TCR with rafts. | Q52537753 | ||
| Membrane compartmentation is required for efficient T cell activation. | Q54132378 | ||
| Monoclonal antibodies to murine CD40 define two distinct functional epitopes | Q71639872 | ||
| Inhibition of IgE binding to mast cells and basophils by monoclonal antibodies to murine IgE | Q72745417 | ||
| TRAF2 is essential for JNK but not NF-kappaB activation and regulates lymphocyte proliferation and survival | Q73925277 | ||
| P433 | issue | 20 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | CD40 molecule | Q21135811 |
| protein-containing complex assembly | Q22295045 | ||
| P304 | page(s) | 15392-15398 | |
| P577 | publication date | 2000-05-01 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | Recruitment of CD40 and tumor necrosis factor receptor-associated factors 2 and 3 to membrane microdomains during CD40 signaling | |
| P478 | volume | 275 |
| Q77589706 | A CD40 Signalosome anchored in lipid rafts leads to constitutive activation of NF-kappaB and autonomous cell growth in B cell lymphomas |
| Q39037203 | A Complex Relationship between TRAF3 and Non-Canonical NF-κB2 Activation in B Lymphocytes |
| Q35214741 | A critical role for TNF receptor-associated factor 1 and Bim down-regulation in CD8 memory T cell survival |
| Q40326255 | A novel mechanism of CD40-induced apoptosis of carcinoma cells involving TRAF3 and JNK/AP-1 activation. |
| Q36843735 | A novel polymorphism of the human CD40 receptor with enhanced function |
| Q43177792 | B cell Rab7 mediates induction of activation-induced cytidine deaminase expression and class-switching in T-dependent and T-independent antibody responses |
| Q39325816 | B cells from African American lupus patients exhibit an activated phenotype. |
| Q34282293 | B lymphocyte activation by contact-mediated interactions with T lymphocytes. |
| Q34242679 | CD19 regulates intrinsic B lymphocyte signal transduction and activation through a novel mechanism of processive amplification |
| Q34969960 | CD20-mediated apoptosis: signalling through lipid rafts |
| Q39645275 | CD40 and LMP-1 both signal from lipid rafts but LMP-1 assembles a distinct, more efficient signaling complex |
| Q34980894 | CD40 and its viral mimic, LMP1: similar means to different ends |
| Q40191634 | CD40 ligand binds to alpha5beta1 integrin and triggers cell signaling |
| Q40015988 | CD40 ligation decreases its protein half-life at the cell surface |
| Q40430095 | CD40 signaling in human dendritic cells is initiated within membrane rafts |
| Q39543670 | CD40 translocation to lipid rafts: signaling requirements and downstream biological events |
| Q28139933 | Caveolin-1 associates with TRAF2 to form a complex that is recruited to tumor necrosis factor receptors |
| Q40761285 | Cellular responses to murine CD40 in a mouse B cell line may be TRAF dependent or independent |
| Q35047148 | Ceramide and cell death receptor clustering |
| Q42631651 | Characterization and expression analysis of TNFR-associated factor 1 (TRAF1) in grass carp Ctenopharyngodon idella |
| Q46130895 | Cholesterol depletion associated with Leishmania major infection alters macrophage CD40 signalosome composition and effector function. |
| Q33839840 | Classical and/or alternative NF-kappaB pathway activation in multiple myeloma |
| Q40732052 | Clustering of CD40 ligand is required to form a functional contact with CD40. |
| Q36699754 | Constitutive CD40 signaling in B cells selectively activates the noncanonical NF-kappaB pathway and promotes lymphomagenesis |
| Q34234140 | Cytokine signaling and Epstein-Barr virus-mediated cell transformation |
| Q40733134 | Cytoplasmic aggregation of TRAF2 and TRAF5 proteins in the Hodgkin-Reed-Sternberg cells |
| Q34580224 | Differential TRAF3 utilization by a variant human CD40 receptor with enhanced signaling |
| Q36369236 | Differential signaling and tumor necrosis factor receptor-associated factor (TRAF) degradation mediated by CD40 and the Epstein-Barr virus oncoprotein latent membrane protein 1 (LMP1). |
| Q40215731 | Ecto-5'-nucleotidase (eN, CD73) is coexpressed with metastasis promoting antigens in human melanoma cells. |
| Q38921402 | Equine infectious anemia virus entry occurs through clathrin-mediated endocytosis |
| Q34095134 | Expression and function of TRAF-3 splice-variant isoforms in human lymphoma cell lines |
| Q44686342 | Functional caveolae are a prerequisite for CD40 signaling in human renal proximal tubule cells |
| Q24338233 | HOIL-1L interacting protein (HOIP) as an NF-kappaB regulating component of the CD40 signaling complex |
| Q28303338 | Hyper immunoglobulin M syndrome due to CD40 deficiency: clinical, molecular, and immunological features |
| Q44900926 | Impact of cholesterol depletion on shape changes, actin reorganization, and signal transduction in neutrophil-like HL-60 cells |
| Q43005389 | Inducible CD40 expression mediates NFkappaB activation and cytokine secretion in human colonic fibroblasts |
| Q38896847 | Induction of an altered CD40 signaling complex by an antagonistic human monoclonal antibody to CD40. |
| Q38874554 | Involvement of the cytoplasmic cysteine-238 of CD40 in its up-regulation of CD23 expression and its enhancement of TLR4-triggered responses |
| Q39685776 | LMP-1's transmembrane domains encode multiple functions required for LMP-1's efficient signaling |
| Q39777437 | LMP1, a viral relative of the TNF receptor family, signals principally from intracellular compartments |
| Q33337033 | Lipid rafts and B-cell activation |
| Q40730109 | Listeriolysin O secreted by Listeria monocytogenes induces NF-kappaB signalling by activating the IkappaB kinase complex |
| Q36506851 | Listeriolysin O: a key protein of Listeria monocytogenes with multiple functions |
| Q27008954 | MHC class II association with lipid rafts on the antigen presenting cell surface |
| Q40663935 | Membrane rafts play a crucial role in receptor activator of nuclear factor kappaB signaling and osteoclast function |
| Q57372095 | Membrane-anchored CD40 Is Processed by the Tumor Necrosis Factor-α-converting Enzyme |
| Q28216544 | Molecular characterization of CD40 signaling intermediates |
| Q34881954 | Molecular mechanisms of B-lymphocyte transformation by Epstein-Barr virus |
| Q34696221 | Molecular mechanisms of TNFR-associated factor 6 (TRAF6) utilization by the oncogenic viral mimic of CD40, latent membrane protein 1 (LMP1). |
| Q46708157 | New insight into the interaction of TRAF2 C-terminal domain with lipid raft microdomains |
| Q40660138 | Pre-assembly of the extracellular domains of CD40 is not necessary for rescue of mouse B cells from anti-immunoglobulin M-induced apoptosis |
| Q36033375 | RIP1 Cleavage in the Kinase Domain Regulates TRAIL-Induced NF-κB Activation and Lymphoma Survival |
| Q28573083 | Raft-partitioning of the ubiquitin ligases Cbl and Nedd4 upon IgE-triggered cell signaling |
| Q40245571 | Rapid CD40-mediated rescue from CD95-induced apoptosis requires TNFR-associated factor-6 and PI3K. |
| Q40623273 | Reactive oxygen species play roles on B cell surface receptor CD40-mediated proximal and distal signaling events: effects of an antioxidant, N-acetyl-L-cysteine treatment |
| Q33187061 | Recruitment of TNF receptor 1 to lipid rafts is essential for TNFalpha-mediated NF-kappaB activation |
| Q38113962 | Regulation of PI-3-Kinase and Akt Signaling in T Lymphocytes and Other Cells by TNFR Family Molecules |
| Q40742977 | Regulation of TRAF2 signaling by self-induced degradation. |
| Q36371153 | Regulation of the subcellular localization of tumor necrosis factor receptor-associated factor (TRAF)2 by TRAF1 reveals mechanisms of TRAF2 signaling |
| Q36403897 | Requirement for TRAF3 in signaling by LMP1 but not CD40 in B lymphocytes |
| Q38179139 | Roles for TNF-receptor associated factor 3 (TRAF3) in lymphocyte functions |
| Q36961046 | Roles of TRAF6 in CD40 signaling |
| Q34364910 | Roles of the kinase TAK1 in TRAF6-dependent signaling by CD40 and its oncogenic viral mimic, LMP1 |
| Q26853280 | Roles of tumor necrosis factor receptor associated factor 3 (TRAF3) and TRAF5 in immune cell functions |
| Q35126555 | Scaffold protein JLP is critical for CD40 signaling in B lymphocytes |
| Q34397107 | Signaling by CD40 and its mimics in B cell activation |
| Q48784822 | Soluble CD40 ligand (sCD40L) provides a new delivery system for targeted treatment: sCD40L-caspase 3 chimeric protein for treating B-cell malignancies |
| Q24683262 | Specific association of glycoprotein B with lipid rafts during herpes simplex virus entry |
| Q44550505 | Store-operated cation entry mediated by CD20 in membrane rafts |
| Q40618791 | Synergistic B cell activation by CD40 and the B cell antigen receptor: role of B lymphocyte antigen receptor-mediated kinase activation and tumor necrosis factor receptor-associated factor regulation. |
| Q34271720 | T3JAM, a novel protein that specifically interacts with TRAF3 and promotes the activation of JNK(1). |
| Q34603380 | TNF receptor-associated factor 3 is required for T cell-mediated immunity and TCR/CD28 signaling |
| Q35143919 | TNF-receptor-associated factors as targets for drug development |
| Q37299479 | TNFR1 signaling kinetics: spatiotemporal control of three phases of IKK activation by posttranslational modification |
| Q89636329 | TRAF2 Ser-11 phosphorylation promotes cytosolic translocation of the CD40 complex to regulate downstream signaling pathways |
| Q37467736 | TRAF2 must bind to cellular inhibitors of apoptosis for tumor necrosis factor (tnf) to efficiently activate nf-{kappa}b and to prevent tnf-induced apoptosis. |
| Q38801811 | TRAF3 as a powerful and multitalented regulator of lymphocyte functions. |
| Q50792035 | TRAF3 forms heterotrimers with TRAF2 and modulates its ability to mediate NF-{kappa}B activation. |
| Q38530616 | TRAF3, ubiquitination, and B-lymphocyte regulation. |
| Q30159856 | TRAF6 activation of PI 3-kinase-dependent cytoskeletal changes is cooperative with Ras and is mediated by an interaction with cytoplasmic Src. |
| Q28506630 | TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-beta |
| Q40587565 | The CD20 calcium channel is localized to microvilli and constitutively associated with membrane rafts: antibody binding increases the affinity of the association through an epitope-dependent cross-linking-independent mechanism. |
| Q35145640 | The CD40-CD154 interaction in B cell-T cell liaisons |
| Q45990226 | The Cytokine Odyssey 2001, a joint meeting of the Society of Leukocyte Biology and the International Cytokine Society. 8-11 November 2001, Maui, Hawaii, USA. |
| Q28198125 | The TNF-receptor-associated factor family: scaffold molecules for cytokine receptors, kinases and their regulators |
| Q24290638 | The c-Abl tyrosine kinase is regulated downstream of the B cell antigen receptor and interacts with CD19 |
| Q35906085 | The multifaceted roles of TRAFs in the regulation of B-cell function. |
| Q35209475 | The regulation of immunoglobulin E class-switch recombination |
| Q35076697 | The roles of membrane microdomains (rafts) in T cell activation |
| Q35145613 | The signaling adaptors and pathways activated by TNF superfamily |
| Q30359929 | The structural basis of hyper IgM deficiency - CD40L mutations. |
| Q57363000 | The transmembranous domain of CD40 determines CD40 partitioning into lipid rafts |
| Q34103388 | The tumour necrosis factor receptor family: life or death choices |
| Q57363947 | Translocation of Ku86/Ku70 to the multiple myeloma cell membrane |
| Q40626565 | Tumor necrosis factor receptor-associated factor (TRAF) 1 regulates CD40-induced TRAF2-mediated NF-kappaB activation |
| Q28511980 | Tumor necrosis factor receptor-associated factor 2 (TRAF2)-deficient B lymphocytes reveal novel roles for TRAF2 in CD40 signaling |
| Q39318861 | Ubiquitination and translocation of TRAF2 is required for activation of JNK but not of p38 or NF-kappaB. |
| Q34184605 | cIAP1-dependent TRAF2 degradation regulates the differentiation of monocytes into macrophages and their response to CD40 ligand |
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