Regulation of TRAF2 signaling by self-induced degradation.

scientific article published on 21 March 2002

Regulation of TRAF2 signaling by self-induced degradation. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M111522200
P8608Fatcat IDrelease_4prz6z3pqna6peih2m457yl2im
P698PubMed publication ID11909853

P50authorGail A BishopQ56650269
P2093author name stringBruce S Hostager
Kevin D Brown
P2860cites workRING fingers mediate ubiquitin-conjugating enzyme (E2)-dependent ubiquitinationQ22010577
Recruitment of CD40 and tumor necrosis factor receptor-associated factors 2 and 3 to membrane microdomains during CD40 signalingQ22253441
A novel family of putative signal transducers associated with the cytoplasmic domain of the 75 kDa tumor necrosis factor receptorQ24318280
CD30-dependent degradation of TRAF2: implications for negative regulation of TRAF signaling and the control of cell survivalQ24605401
Regulation of the Src family tyrosine kinase Blk through E6AP-mediated ubiquitinationQ24656742
RING for destruction?Q28144245
Raft-partitioning of the ubiquitin ligases Cbl and Nedd4 upon IgE-triggered cell signalingQ28573083
Tumor necrosis factor receptor-associated factors (TRAFs)--a family of adapter proteins that regulates life and deathQ28609905
TRAF2-mediated activation of NF-kappa B by TNF receptor 2 and CD40Q28610812
Ubiquitin-dependent c-Jun degradation in vivo is mediated by the delta domainQ29614381
Ubiquitin ligase activity and tyrosine phosphorylation underlie suppression of growth factor signaling by c-Cbl/Sli-1Q29617290
Early lethality, functional NF-kappaB activation, and increased sensitivity to TNF-induced cell death in TRAF2-deficient miceQ29618716
Signaling by CD40 and its mimics in B cell activationQ34397107
Differential signaling and tumor necrosis factor receptor-associated factor (TRAF) degradation mediated by CD40 and the Epstein-Barr virus oncoprotein latent membrane protein 1 (LMP1).Q36369236
Association of TRAF1, TRAF2, and TRAF3 with an Epstein-Barr virus LMP1 domain important for B-lymphocyte transformation: role in NF-kappaB activationQ36564433
Characterization of the roles of TNF receptor-associated factor 6 in CD40-mediated B lymphocyte effector functionsQ40908092
Signaling via major histocompatibility complex class II molecules and antigen receptors enhances the B cell response to gp39/CD40 ligandQ41666025
Efficient cDNA expression vectors for stable and transient expression of HLA-DR in transfected fibroblast and lymphoid cellsQ41672956
CD40-tumor necrosis factor receptor-associated factor (TRAF) interactions: regulation of CD40 signaling through multiple TRAF binding sites and TRAF hetero-oligomerizationQ42060069
Coronin and vacuolin identify consecutive stages of a late, actin-coated endocytic compartment in DictyosteliumQ48052817
Multiple Carboxyl-Terminal Regions of the EBV Oncoprotein, Latent Membrane Protein 1, Cooperatively Regulate Signaling to B Lymphocytes Via TNF Receptor-Associated Factor (TRAF)-Dependent and TRAF-Independent MechanismsQ57791793
T-cell-mediated regulation of osteoclastogenesis by signalling cross-talk between RANKL and IFN-γQ59064307
P433issue22
P407language of work or nameEnglishQ1860
P304page(s)19433-19438
P577publication date2002-03-21
P1433published inJournal of Biological ChemistryQ867727
P1476titleRegulation of TRAF2 signaling by self-induced degradation
P478volume277

Reverse relations

cites work (P2860)
Q39037203A Complex Relationship between TRAF3 and Non-Canonical NF-κB2 Activation in B Lymphocytes
Q28271411A RING finger ubiquitin ligase is protected from autocatalyzed ubiquitination and degradation by binding to ubiquitin-specific protease USP7
Q40326255A novel mechanism of CD40-induced apoptosis of carcinoma cells involving TRAF3 and JNK/AP-1 activation.
Q28187818A role for NF-kappaB essential modifier/IkappaB kinase-gamma (NEMO/IKKgamma) ubiquitination in the activation of the IkappaB kinase complex by tumor necrosis factor-alpha
Q40472871An atypical tumor necrosis factor (TNF) receptor-associated factor-binding motif of B cell-activating factor belonging to the TNF family (BAFF) receptor mediates induction of the noncanonical NF-kappaB signaling pathway.
Q24655287Atypical ubiquitin chains: new molecular signals. 'Protein Modifications: Beyond the Usual Suspects' review series
Q91792214CD40 induces renal cell carcinoma-specific differential regulation of TRAF proteins, ASK1 activation and JNK/p38-mediated, ROS-dependent mitochondrial apoptosis
Q40015988CD40 ligation decreases its protein half-life at the cell surface
Q34708427Changes in gene expression profiling of apoptotic genes in neuroblastoma cell lines upon retinoic acid treatment
Q38530635Cloaked in ubiquitin, a killer hides in plain sight: the molecular regulation of RIPK1.
Q35227386Downregulation of ubiquitin inhibits the proliferation and radioresistance of non-small cell lung cancer cells in vitro and in vivo
Q34346080Emerging complexity of protein ubiquitination in the NF-κB pathway
Q35609384Enhanced Toll-like receptor (TLR) responses of TNFR-associated factor 3 (TRAF3)-deficient B lymphocytes
Q39544175Exosomal sorting of the viral oncoprotein LMP1 is restrained by TRAF2 association at signalling endosomes
Q44422902Fas-associated Death Domain Protein and Caspase-8 Are Not Recruited to the Tumor Necrosis Factor Receptor 1 Signaling Complex during Tumor Necrosis Factor-induced Apoptosis
Q37948116How do pleiotropic kinase hubs mediate specific signaling by TNFR superfamily members?
Q36085601IAPs, RINGs and ubiquitylation
Q38896847Induction of an altered CD40 signaling complex by an antagonistic human monoclonal antibody to CD40.
Q87399890LRRC19 expressed in the kidney induces TRAF2/6-mediated signals to prevent infection by uropathogenic bacteria
Q39481105MicroRNA-17 Suppresses TNF-α Signaling by Interfering with TRAF2 and cIAP2 Association in Rheumatoid Arthritis Synovial Fibroblasts
Q37474929Molecular mechanism and function of CD40/CD40L engagement in the immune system.
Q37178911Noncanonical NF-kappaB activation requires coordinated assembly of a regulatory complex of the adaptors cIAP1, cIAP2, TRAF2 and TRAF3 and the kinase NIK.
Q35036565RING finger ubiquitin protein ligases: implications for tumorigenesis, metastasis and for molecular targets in cancer
Q40555067Receptor interacting protein is ubiquitinated by cellular inhibitor of apoptosis proteins (c-IAP1 and c-IAP2) in vitro
Q40373883Reciprocal activities between herpes simplex virus type 1 regulatory protein ICP0, a ubiquitin E3 ligase, and ubiquitin-specific protease USP7.
Q36371153Regulation of the subcellular localization of tumor necrosis factor receptor-associated factor (TRAF)2 by TRAF1 reveals mechanisms of TRAF2 signaling
Q36403897Requirement for TRAF3 in signaling by LMP1 but not CD40 in B lymphocytes
Q36961046Roles of TRAF6 in CD40 signaling
Q39814540Roles of the TRAF2/3 binding site in differential B cell signaling by CD40 and its viral oncogenic mimic, LMP1
Q26853280Roles of tumor necrosis factor receptor associated factor 3 (TRAF3) and TRAF5 in immune cell functions
Q41791635Suppressive effect of reactive oxygen species on CD40-induced B cell activation
Q28478440Switches, excitable responses and oscillations in the Ring1B/Bmi1 ubiquitination system
Q24292812TEB4 is a C4HC3 RING finger-containing ubiquitin ligase of the endoplasmic reticulum
Q35143919TNF-receptor-associated factors as targets for drug development
Q36479735TNFR-associated factor 2 deficiency in B lymphocytes predisposes to chronic lymphocytic leukemia/small lymphocytic lymphoma in mice.
Q37769438TRAF-mediated regulation of immune and inflammatory responses
Q89636329TRAF2 Ser-11 phosphorylation promotes cytosolic translocation of the CD40 complex to regulate downstream signaling pathways
Q36053266TRAF2: a double-edged sword?
Q38801811TRAF3 as a powerful and multitalented regulator of lymphocyte functions.
Q24300996TRAF3 controls activation of the canonical and alternative NFkappaB by the lymphotoxin beta receptor
Q41485983TRAF4 promotes lung cancer aggressiveness by modulating tumor microenvironment in normal fibroblasts
Q36749651TWEAK-FN14 signaling induces lysosomal degradation of a cIAP1-TRAF2 complex to sensitize tumor cells to TNFalpha.
Q35145640The CD40-CD154 interaction in B cell-T cell liaisons
Q92755025The DNA repair protein SHPRH is a nucleosome-stimulated ATPase and a nucleosome-E3 ubiquitin ligase
Q62125897The Polycomb Protein Ring1B Generates Self Atypical Mixed Ubiquitin Chains Required for Its In Vitro Histone H2A Ligase Activity
Q35906085The multifaceted roles of TRAFs in the regulation of B-cell function.
Q33343831The ubiquitination code: a signalling problem
Q40183663Tumor necrosis factor receptor 2 signaling induces selective c-IAP1-dependent ASK1 ubiquitination and terminates mitogen-activated protein kinase signaling
Q28511980Tumor necrosis factor receptor-associated factor 2 (TRAF2)-deficient B lymphocytes reveal novel roles for TRAF2 in CD40 signaling
Q39872674Tumor necrosis factor receptor-associated factor-1 enhances proinflammatory TNF receptor-2 signaling and modifies TNFR1-TNFR2 cooperation
Q34185821Tumor necrosis factor signaling.
Q36108376Ubiquitin chains in the ladder of MAPK signaling
Q50326522X-linked inhibitor of apoptosis-associated factor 1 regulates TNF receptor 1 complex stability
Q34184605cIAP1-dependent TRAF2 degradation regulates the differentiation of monocytes into macrophages and their response to CD40 ligand