scholarly article | Q13442814 |
P50 | author | Daniel F Legler | Q54858768 |
Olivier Micheau | Q60314905 | ||
Jürg Tschopp | Q28320791 | ||
P2093 | author name string | Marie-Agnès Doucey | |
Claude Bron | |||
P2860 | cites work | Recruitment of CD40 and tumor necrosis factor receptor-associated factors 2 and 3 to membrane microdomains during CD40 signaling | Q22253441 |
Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule | Q24290576 | ||
TAK1 is a ubiquitin-dependent kinase of MKK and IKK | Q24291454 | ||
The NF-kappa B and I kappa B proteins: new discoveries and insights | Q24313579 | ||
TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways | Q24317441 | ||
The TNF receptor 1-associated protein TRADD signals cell death and NF-kappa B activation | Q24318742 | ||
Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity | Q27860643 | ||
Lipid rafts and signal transduction | Q28131735 | ||
Caveolin-1 associates with TRAF2 to form a complex that is recruited to tumor necrosis factor receptors | Q28139933 | ||
Recruitment of the IKK signalosome to the p55 TNF receptor: RIP and A20 bind to NEMO (IKKgamma) upon receptor stimulation | Q28141339 | ||
CD95's deadly mission in the immune system | Q28142072 | ||
Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain | Q28142613 | ||
CD40 signaling in human dendritic cells is initiated within membrane rafts | Q40430095 | ||
Molecular mechanisms of ceramide-mediated CD95 clustering | Q43642943 | ||
The antitumor ether lipid ET-18-OCH(3) induces apoptosis through translocation and capping of Fas/CD95 into membrane rafts in human leukemic cells | Q43819664 | ||
Restricted localization of the TNF receptor CD120a to lipid rafts: a novel role for the death domain | Q43950694 | ||
Structure and origin of ordered lipid domains in biological membranes. | Q52186070 | ||
Ceramide enables fas to cap and kill. | Q52542714 | ||
CD95 Signaling via Ceramide-rich Membrane Rafts | Q57371964 | ||
Apoptotic, non-apoptotic, and anti-apoptotic pathways of tumor necrosis factor signalling | Q58435118 | ||
TNF is here to stay! | Q61819239 | ||
The distinct roles of TRAF2 and RIP in IKK activation by TNF-R1: TRAF2 recruits IKK to TNF-R1 while RIP mediates IKK activation | Q73745042 | ||
A CD40 Signalosome anchored in lipid rafts leads to constitutive activation of NF-kappaB and autonomous cell growth in B cell lymphomas | Q77589706 | ||
TNF-induced recruitment and activation of the IKK complex require Cdc37 and Hsp90 | Q28203709 | ||
The TNF and TNF receptor superfamilies: integrating mammalian biology | Q28203717 | ||
Death receptors: signaling and modulation | Q28280897 | ||
LAT palmitoylation: its essential role in membrane microdomain targeting and tyrosine phosphorylation during T cell activation | Q28281516 | ||
A protein related to a proteasomal subunit binds to the intracellular domain of the p55 TNF receptor upstream to its 'death domain' | Q28292545 | ||
Modulation of life and death by the TNF receptor superfamily | Q28295043 | ||
A neutral sphingomyelinase resides in sphingolipid-enriched microdomains and is inhibited by the caveolin-scaffolding domain: potential implications in tumour necrosis factor signalling | Q28363285 | ||
Raft-partitioning of the ubiquitin ligases Cbl and Nedd4 upon IgE-triggered cell signaling | Q28573083 | ||
TRAF2-mediated activation of NF-kappa B by TNF receptor 2 and CD40 | Q28610812 | ||
Ubiquitin-dependent c-Jun degradation in vivo is mediated by the delta domain | Q29614381 | ||
The death domain kinase RIP mediates the TNF-induced NF-kappaB signal | Q29617727 | ||
Structure and function of sphingolipid- and cholesterol-rich membrane rafts | Q29618518 | ||
NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation | Q29618715 | ||
Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-kappaB activation prevents cell death | Q29620021 | ||
Lipid domain structure of the plasma membrane revealed by patching of membrane components | Q29620204 | ||
Apoptotic molecular machinery: vastly increased complexity in vertebrates revealed by genome comparisons | Q30658935 | ||
Tumor necrosis factor receptor and Fas signaling mechanisms. | Q33652491 | ||
An essential role for membrane rafts in the initiation of Fas/CD95-triggered cell death in mouse thymocytes | Q33757511 | ||
SUMO, ubiquitin's mysterious cousin | Q33939449 | ||
The differential miscibility of lipids as the basis for the formation of functional membrane rafts. | Q34067848 | ||
Activation-induced cell death | Q34282369 | ||
Signal transduction by tumor necrosis factor and its relatives | Q34341941 | ||
Aggregation of lipid rafts accompanies signaling via the T cell antigen receptor | Q36326042 | ||
Differential signaling and tumor necrosis factor receptor-associated factor (TRAF) degradation mediated by CD40 and the Epstein-Barr virus oncoprotein latent membrane protein 1 (LMP1). | Q36369236 | ||
NF-kappaB signals induce the expression of c-FLIP. | Q39460566 | ||
CD40 and LMP-1 both signal from lipid rafts but LMP-1 assembles a distinct, more efficient signaling complex | Q39645275 | ||
Molecular ordering of the initial signaling events of CD95. | Q39676008 | ||
P433 | issue | 5 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | NF-κB | Q411114 |
membrane raft | Q424178 | ||
TNF | Q18032037 | ||
P304 | page(s) | 655-664 | |
P577 | publication date | 2003-05-01 | |
P1433 | published in | Immunity | Q6005457 |
P1476 | title | Recruitment of TNF receptor 1 to lipid rafts is essential for TNFalpha-mediated NF-kappaB activation | |
P478 | volume | 18 |
Q28287278 | A Novel TRAF6 binding site in MALT1 defines distinct mechanisms of NF-kappaB activation by API2middle dotMALT1 fusions |
Q33818158 | A differential role for endocytosis in receptor-mediated activation of Nox1. |
Q36089051 | A pervasive role of ubiquitin conjugation in activation and termination of IkappaB kinase pathways |
Q37728850 | A20: from ubiquitin editing to tumour suppression |
Q24301284 | AIP1/DAB2IP, a novel member of the Ras-GAP family, transduces TRAF2-induced ASK1-JNK activation |
Q37273750 | Active uptake of dendritic cell-derived exovesicles by epithelial cells induces the release of inflammatory mediators through a TNF-alpha-mediated pathway |
Q46909234 | Acute ethanol treatment modulates Toll-like receptor-4 association with lipid rafts |
Q34707087 | Age-dependent accumulation of ubiquitinated 2',3'-cyclic nucleotide 3'-phosphodiesterase in myelin lipid rafts |
Q37357098 | Altering the sphingolipid acyl chain composition prevents LPS/GLN-mediated hepatic failure in mice by disrupting TNFR1 internalization |
Q44976868 | An evolutionary conserved pathway of nuclear factor-kappaB activation involving caspase-mediated cleavage and N-end rule pathway-mediated degradation of IkappaBalpha |
Q49790910 | An unexpected link between fatty acid synthase and cholesterol synthesis in proinflammatory macrophage activation |
Q40536268 | Analysis of human tumour necrosis factor receptor 1 dominant-negative mutants reveals a major region controlling cell surface expression |
Q35886318 | Analysis of lipid-composition changes in plasma membrane microdomains |
Q34973492 | Antagonistic TNF receptor one-specific antibody (ATROSAB): receptor binding and in vitro bioactivity |
Q35023022 | Anti-inflammatory effect of targeted delivery of SOD to endothelium: mechanism, synergism with NO donors and protective effects in vitro and in vivo |
Q35207610 | Apoptosis modulation as a promising target for treatment of systemic sclerosis |
Q24537608 | BS69, a specific adaptor in the latent membrane protein 1-mediated c-Jun N-terminal kinase pathway |
Q38731779 | Brefeldin A-Inhibited Guanine Nucleotide-Exchange Factor 1 (BIG1) Governs the Recruitment of Tumor Necrosis Factor Receptor-Associated Factor 2 (TRAF2) to Tumor Necrosis Factor Receptor 1 (TNFR1) Signaling Complexes |
Q52308826 | CADM1 is essential for KSHV-encoded vGPCR-and vFLIP-mediated chronic NF-κB activation. |
Q40177590 | CD30 activates both the canonical and alternative NF-kappaB pathways in anaplastic large cell lymphoma cells |
Q35083839 | Caveolae participate in tumor necrosis factor receptor 1 signaling and internalization in a human endothelial cell line |
Q38979542 | Cell fate decisions regulated by K63 ubiquitination of tumor necrosis factor receptor 1. |
Q64114610 | Cholesterol Sulfotransferase SULT2B1b Modulates Sensitivity to Death Receptor Ligand TNFα in Castration-Resistant Prostate Cancer |
Q92263460 | Cholesterol restricts lymphotoxin β receptor-triggered NF-κB signaling |
Q36028155 | Clathrin- and non-clathrin-mediated endocytic regulation of cell signalling |
Q38530635 | Cloaked in ubiquitin, a killer hides in plain sight: the molecular regulation of RIPK1. |
Q37715776 | Control of death receptor ligand activity by posttranslational modifications. |
Q27657476 | Crystal structure of the NEMO ubiquitin-binding domain in complex with Lys 63-linked di-ubiquitin |
Q33939106 | DR5-mediated DISC controls caspase-8 cleavage and initiation of apoptosis in human glioblastomas. |
Q24299573 | De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling |
Q42123656 | Death Receptor 5 Networks Require Membrane Cholesterol for Proper Structure and Function. |
Q37257117 | Decrease in tumor necrosis factor-alpha receptor-associated death domain results from ubiquitin-dependent degradation in obstructive renal injury in rats |
Q38822173 | Deletions in the cytoplasmic domain of iRhom1 and iRhom2 promote shedding of the TNF receptor by the protease ADAM17. |
Q36241231 | Deregulated TGF-beta signaling in leukemogenesis |
Q39104729 | Dietary essential α-linolenic acid and linoleic acid differentially modulate TNFα-induced NFκB activity in FADS2-deficient HEK-293 cells |
Q46418731 | Differential effects of lipoprotein lipase on tumor necrosis factor-alpha and interferon-gamma-mediated gene expression in human endothelial cells |
Q33999606 | Differential inhibition of TRAIL-mediated DR5-DISC formation by decoy receptors 1 and 2. |
Q40540260 | Distinct mechanisms determine the patterns of differential activation of H-Ras, N-Ras, K-Ras 4B, and M-Ras by receptors for growth factors or antigen. |
Q33585802 | Dynamic cross-talk analysis among TNF-R, TLR-4 and IL-1R signalings in TNFalpha-induced inflammatory responses |
Q39768159 | Dynamics of RASSF1A/MOAP-1 association with death receptors. |
Q41932639 | Dynamics of mitochondrial raft-like microdomains in cell life and death. |
Q35910540 | Effector CD4+ T cells generate intermediate caspase activity and cleavage of caspase-8 substrates |
Q36687046 | Electrophilic nitro-fatty acids inhibit vascular inflammation by disrupting LPS-dependent TLR4 signalling in lipid rafts. |
Q36732184 | Essential roles of receptor-interacting protein and TRAF2 in oxidative stress-induced cell death |
Q33231442 | Extracellular TNFR1 release requires the calcium-dependent formation of a nucleobindin 2-ARTS-1 complex |
Q52316878 | Factor VIIa induces anti-inflammatory signaling via EPCR and PAR1. |
Q24320142 | Flotillin-2 expression in the human gut: from a cell model to human tissue in health and inflammatory bowel diseases |
Q39724559 | Function of membrane rafts in viral lifecycles and host cellular response |
Q24321317 | Functional analysis of the posttranslational modifications of the death receptor 6 |
Q33795250 | G-protein-coupled-receptor kinases mediate TNFα-induced NFκB signalling via direct interaction with and phosphorylation of IκBα. |
Q90011228 | GIT1 regulates angiogenic factor secretion in bone marrow mesenchymal stem cells via NF-κB/Notch signalling to promote angiogenesis |
Q49787949 | Ganglioside GM1 contributes to extracellular/intracellular regulation of insulin resistance, impairment of insulin signaling and down-stream eNOS activation, in human aortic endothelial cells after short- or long-term exposure to TNFα. |
Q64254072 | Gangliosides Contribute to Vascular Insulin Resistance |
Q28580654 | Glial cell line-derived neurotrophic factor-dependent recruitment of Ret into lipid rafts enhances signaling by partitioning Ret from proteasome-dependent degradation |
Q99419127 | HRG switches TNFR1-mediated cell survival to apoptosis in Hepatocellular Carcinoma |
Q37296344 | HSP70 interacts with TRAF2 and differentially regulates TNFalpha signalling in human colon cancer cells |
Q90028528 | Herpes simplex virus 1 ICP6 impedes TNF receptor 1-induced necrosome assembly during compartmentalization to detergent-resistant membrane vesicles |
Q35182251 | Human T-cell leukemia virus type 1 (HTLV-1) tax requires CADM1/TSLC1 for inactivation of the NF-κB inhibitor A20 and constitutive NF-κB signaling |
Q36085601 | IAPs, RINGs and ubiquitylation |
Q43125086 | Identification of a lysine-rich region of Fas as a raft nanodomain targeting signal necessary for Fas-mediated cell death. |
Q37424031 | Impaired TNFalpha-induced A20 expression in E1A/Ras-transformed cells |
Q35099711 | Impaired regulation of NF-kappaB and increased susceptibility to colitis-associated tumorigenesis in CYLD-deficient mice |
Q24312187 | Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes |
Q24309469 | Inflammatory cardiac valvulitis in TAX1BP1-deficient mice through selective NF-kappaB activation |
Q35989359 | Inhibition of cytokine signaling in human retinal endothelial cells through modification of caveolae/lipid rafts by docosahexaenoic acid |
Q39410061 | Inhibition of latent membrane protein 1 impairs the growth and tumorigenesis of latency II Epstein-Barr virus-transformed T cells. |
Q36498514 | Inhibition of proinflammatory and innate immune signaling pathways by a cytomegalovirus RIP1-interacting protein |
Q35951508 | Inhibition of toll-like receptor and cytokine signaling--a unifying theme in ischemic tolerance |
Q35856781 | Interferon regulatory factor 7 is activated by a viral oncoprotein through RIP-dependent ubiquitination. |
Q35150394 | Intracellular lipid flux and membrane microdomains as organizing principles in inflammatory cell signaling |
Q36597952 | Intracellular signals and events activated by cytokines of the tumor necrosis factor superfamily: From simple paradigms to complex mechanisms. |
Q41933362 | Intracellular triggering of Fas aggregation and recruitment of apoptotic molecules into Fas-enriched rafts in selective tumor cell apoptosis |
Q41189574 | JMJD8 is a positive regulator of TNF-induced NF-κB signaling |
Q41830093 | LAPTM5 protein is a positive regulator of proinflammatory signaling pathways in macrophages |
Q37233180 | Life and death by death receptors |
Q52553014 | Ligand-independent redistribution of Fas (CD95) into lipid rafts mediates clonotypic T cell death. |
Q51323580 | Lipid Rafts Promote trans Fatty Acid-Induced Inflammation in Human Umbilical Vein Endothelial Cells. |
Q34154684 | Lipid based therapy for ulcerative colitis-modulation of intestinal mucus membrane phospholipids as a tool to influence inflammation. |
Q35101890 | Lipid raft redox signaling: molecular mechanisms in health and disease |
Q26998351 | Lipid raft: A floating island of death or survival |
Q37446112 | Lipid rafts and caveolin-1 coordinate interleukin-1beta (IL-1beta)-dependent activation of NFkappaB by controlling endocytosis of Nox2 and IL-1beta receptor 1 from the plasma membrane |
Q36719287 | Lipid rafts determine clustering of STIM1 in endoplasmic reticulum-plasma membrane junctions and regulation of store-operated Ca2+ entry (SOCE) |
Q38827777 | Lipid rafts in immune signalling: current progress and future perspective. |
Q37665498 | Lipid rafts promote liver cancer cell proliferation and migration by up-regulation of TLR7 expression |
Q36984127 | Localization of A20 to a lysosome-associated compartment and its role in NFkappaB signaling |
Q24306882 | MYADM controls endothelial barrier function through ERM-dependent regulation of ICAM-1 expression |
Q30490333 | Macrophage sphingomyelin synthase 2 deficiency decreases atherosclerosis in mice |
Q33672489 | Many checkpoints on the road to cell death: regulation of Fas-FasL interactions and Fas signaling in peripheral immune responses |
Q38078229 | Mechanisms regulating neutrophil survival and cell death. |
Q37118254 | Membrane raft redox signalosomes in endothelial cells |
Q26852802 | Membrane trafficking of death receptors: implications on signalling |
Q37307064 | Microbial Degradation of Cellular Kinases Impairs Innate Immune Signaling and Paracrine TNFα Responses |
Q40387341 | N-3 vs. n-6 fatty acids differentially influence calcium signalling and adhesion of inflammatory activated monocytes: impact of lipid rafts. |
Q28271031 | NF-kappaB and the immune response |
Q36964401 | NF-κB pathway activators as potential ageing biomarkers: targets for new therapeutic strategies. |
Q97636083 | NORE1A directs apoptotic switch of TNF signaling through reciprocal modulation of ITCH-mediated destruction of TNFRI and BAX |
Q55440020 | On the modeling and analysis of the biological regulatory network of NF- $${\kappa }$$ κ B activation in HIV-1 infection |
Q24652618 | PKC phosphorylation of TRAF2 mediates IKKalpha/beta recruitment and K63-linked polyubiquitination |
Q92425057 | Palmitoylation is required for TNF-R1 signaling |
Q39089524 | Piecing it together: Unraveling the elusive structure-function relationship in single-pass membrane receptors |
Q40436916 | Proteasome inhibition induces TNFR1 shedding from human airway epithelial (NCI-H292) cells |
Q90227518 | Pseudomonas aeruginosa quorum-sensing metabolite induces host immune cell death through cell surface lipid domain dissolution |
Q42661602 | RIP1 comes back to life as a cell death regulator in TNFR1 signaling |
Q28288337 | RIP1, a kinase on the crossroads of a cell's decision to live or die |
Q37774919 | Reactive oxygen species in TNFalpha-induced signaling and cell death. |
Q40555067 | Receptor interacting protein is ubiquitinated by cellular inhibitor of apoptosis proteins (c-IAP1 and c-IAP2) in vitro |
Q50100385 | Regulated intramembrane proteolysis: emergent role in cell signalling pathways |
Q42810176 | Regulation of death complexes formation in tumor necrosis factor receptor signaling |
Q37628447 | Regulation of death receptor signaling by the ubiquitin system |
Q27690854 | Regulation of inflammatory and antiviral signaling by A20. |
Q28262381 | Regulation of tumour necrosis factor signalling: live or let die |
Q36017850 | Release of full-length 55-kDa TNF receptor 1 in exosome-like vesicles: a mechanism for generation of soluble cytokine receptors |
Q57372671 | Requirement of Oxidation-dependent CD40 Homodimers for CD154/CD40 Bidirectional Signaling |
Q28476834 | Restoration of IFNγR subunit assembly, IFNγ signaling and parasite clearance in Leishmania donovani infected macrophages: role of membrane cholesterol |
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Q24294081 | Role of GD3-CLIPR-59 association in lymphoblastoid T cell apoptosis triggered by CD95/Fas |
Q38344567 | Role of mitochondrial raft-like microdomains in the regulation of cell apoptosis. |
Q52622109 | Role of sphingomyelin synthesis in pulmonary endothelial cell cytoskeletal activation and endotoxin-induced lung injury. |
Q36961046 | Roles of TRAF6 in CD40 signaling |
Q49886934 | ST6Gal-I sialyltransferase promotes tumor necrosis factor (TNF)-mediated cancer cell survival via sialylation of the TNF receptor 1 (TNFR1) death receptor |
Q24294324 | Selective regulation of tumor necrosis factor-induced Erk signaling by Src family kinases and the T cell protein tyrosine phosphatase |
Q29618714 | Sensing of Lys 63-linked polyubiquitination by NEMO is a key event in NF-kappaB activation [corrected] |
Q30493800 | Signaling components of redox active endosomes: the redoxosomes. |
Q28512633 | Signaling pathways from membrane lipid rafts to JNK1 activation in reactive nitrogen species-induced non-apoptotic cell death |
Q29616428 | Signalling pathways of the TNF superfamily: a double-edged sword |
Q91878626 | Soft extracellular matrix enhances inflammatory activation of mesenchymal stromal cells to induce monocyte production and trafficking |
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Q35092629 | Specific elimination of effector memory CD4+ T cells due to enhanced Fas signaling complex formation and association with lipid raft microdomains |
Q38963276 | Squalene synthase induces tumor necrosis factor receptor 1 enrichment in lipid rafts to promote lung cancer metastasis |
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Q40319830 | TRAIL-induced apoptosis in U-1242 MG glioma cells |
Q36268329 | Targeting the Fas/Fas ligand pathway in cancer. |
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