The Gata3 transcription factor is required for the survival of embryonic and adult sympathetic neurons

scientific journal article

The Gata3 transcription factor is required for the survival of embryonic and adult sympathetic neurons is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1523/JNEUROSCI.0175-10.2010
P932PMC publication ID6634692
P698PubMed publication ID20702712
P5875ResearchGate publication ID45629618

P50authorTobias ReiffQ60036094
Rosanna ParlatoQ40638245
P2093author name stringFrank G Grosveld
Günther Schütz
Dorota Kurek
Hermann Rohrer
Jutta Stubbusch
Konstantina Tsarovina
P2860cites workGATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiationQ24569631
GATA-3 maintains the differentiation of the luminal cell fate in the mammary glandQ24649647
To be, or not to be: NF-kappaB is the answer--role of Rel/NF-kappaB in the regulation of apoptosisQ28190313
Lbx1 and Tlx3 are opposing switches in determining GABAergic versus glutamatergic transmitter phenotypesQ28505385
The homeobox gene Phox2b is essential for the development of autonomic neural crest derivativesQ28505510
Ascl1/Mash1 is required for the development of central serotonergic neuronsQ28507929
Essential role of Gata transcription factors in sympathetic neuron developmentQ28509275
Hand2 determines the noradrenergic phenotype in the mouse sympathetic nervous systemQ28510580
Gata2 is a tissue-specific post-mitotic selector gene for midbrain GABAergic neuronsQ28510842
BMP signaling regulates sympathetic nervous system development through Smad4-dependent and -independent pathwaysQ28511625
Gata3 loss leads to embryonic lethality due to noradrenaline deficiency of the sympathetic nervous systemQ28512290
Gata3 participates in a complex transcriptional feedback network to regulate sympathoadrenal differentiation.Q52007983
Target-dependent specification of the neurotransmitter phenotype: cholinergic differentiation of sympathetic neurons is mediated in vivo by gp 130 signaling.Q52032809
Specification of the central noradrenergic phenotype by the homeobox gene Phox2b.Q52169701
The Phox2 homeodomain proteins are sufficient to promote the development of sympathetic neurons.Q52174960
The developmental expression of choline acetyltransferase (ChAT) and the neuropeptide VIP in chick sympathetic neurons: evidence for different regulatory events in cholinergic differentiation.Q52190822
Relationship between differentiation and terminal mitosis: chick sensory and ciliary neurons differentiate after terminal mitosis of precursor cells, whereas sympathetic neurons continue to divide after differentiation.Q52254715
Specific ablation of the transcription factor CREB in sympathetic neurons surprisingly protects against developmentally regulated apoptosisQ57073204
The anti-apoptotic protein ITA is essential for NGF-mediated survival of embryonic chick neuronsQ60215412
The survival of early chick sympathetic neurons in vitro is dependent on a suitable substrate but independent of NGFQ69721319
Effects of exposure to nerve growth factor antibodies on the developing nervous system of the rat: An experimental autoimmune approachQ72443968
Massive cell death of immature hematopoietic cells and neurons in Bcl-x-deficient miceQ72600081
Nerve growth factor-dependent activation of NF-kappaB contributes to survival of sympathetic neuronsQ77679780
Defects in sensory and autonomic ganglia and absence of locus coeruleus in mice deficient for the homeobox gene Phox2aQ28512489
Transcription factor GATA-3 alters pathway selection of olivocochlear neurons and affects morphogenesis of the earQ28585452
Insm1 (IA-1) is a crucial component of the transcriptional network that controls differentiation of the sympatho-adrenal lineageQ28589738
Lack of an adrenal cortex in Sf1 mutant mice is compatible with the generation and differentiation of chromaffin cellsQ28589760
Inactivation of bcl-2 results in progressive degeneration of motoneurons, sympathetic and sensory neurons during early postnatal developmentQ28590612
Widespread elimination of naturally occurring neuronal death in Bax-deficient miceQ28591049
Transcriptome and phenotypic analysis reveals Gata3-dependent signalling pathways in murine hair folliclesQ28593467
The role of Phox2B in chromaffin cell developmentQ28594527
Transcription-dependent and -independent control of neuronal survival by the PI3K-Akt signaling pathwayQ34278037
Phosphatidylinositol 3-kinase and Akt protein kinase are necessary and sufficient for the survival of nerve growth factor-dependent sympathetic neurons.Q34462515
Specification of catecholaminergic and serotonergic neurons.Q34718055
Growth and survival signals controlling sympathetic nervous system developmentQ36196524
Activation of nuclear factor kappaB and Bcl-x survival gene expression by nerve growth factor requires tyrosine phosphorylation of IkappaBalpha.Q36375798
Proapoptotic multidomain Bcl-2/Bax-family proteins: mechanisms, physiological roles, and therapeutic opportunitiesQ36490192
Conditional deletion of Hand2 reveals critical functions in neurogenesis and cell type-specific gene expression for development of neural crest-derived noradrenergic sympathetic ganglion neuronsQ36839308
Bcl-2-regulated apoptosis: mechanism and therapeutic potentialQ36880621
Regulatory logic of neuronal diversity: terminal selector genes and selector motifs.Q37068535
The bHLH transcription factor Hand2 is essential for the maintenance of noradrenergic properties in differentiated sympathetic neuronsQ37352684
The development of the chromaffin cell lineage from the neural crestQ37580453
Immunization of adult rats against 2.5 S NGF: Effects on the peripheral sympathetic nervous systemQ39274091
Neuroblastoma phox2b variants stimulate proliferation and dedifferentiation of immature sympathetic neuronsQ39749759
Analysis of Ret knockin mice reveals a critical role for IKKs, but not PI 3-K, in neurotrophic factor-induced survival of sympathetic neurons.Q39979628
Inducible gene deletion in astroglia and radial glia--a valuable tool for functional and lineage analysisQ40284616
Role of PI 3-kinase, Akt and Bcl-2-related proteins in sustaining the survival of neurotrophic factor-independent adult sympathetic neuronsQ42947803
Coupling Met to specific pathways results in distinct developmental outcomesQ43656791
GATA-4 regulates Bcl-2 expression in ovarian granulosa cell tumorsQ44246851
Conditional inactivation of glucocorticoid receptor gene in dopamine-beta-hydroxylase cells impairs chromaffin cell survivalQ46226377
Bcl-x is required for proper development of the mouse substantia nigra.Q46610659
The bHLH transcription factor hand2 is essential for noradrenergic differentiation of sympathetic neuronsQ47073564
Hearing loss following Gata3 haploinsufficiency is caused by cochlear disorderQ47320318
Multiple roles for hepatocyte growth factor in sympathetic neuron development.Q47992125
Neuronal precursor cells in chick dorsal root ganglia: differentiation and survival in vitroQ48097872
GATA-3 is involved in the development of serotonergic neurons in the caudal raphe nucleiQ48188436
Delays in neuronal differentiation in Mash1/Ascl1 mutantsQ48553813
TrkA expression levels of sympathetic neurons correlate with NGF-dependent survival during development and after treatment with retinoic acidQ48569566
Magnetic resonance diffusion tensor microimaging reveals a role for Bcl-x in brain development and homeostasis.Q49022404
Spatial and temporal specification of neural fates by transcription factor codes.Q51976711
P433issue32
P407language of work or nameEnglishQ1860
P921main subjectGATA binding protein 3Q21497809
P304page(s)10833-10843
P577publication date2010-08-01
P1433published inJournal of NeuroscienceQ1709864
P1476titleThe Gata3 transcription factor is required for the survival of embryonic and adult sympathetic neurons
P478volume30

Reverse relations

cites work (P2860)
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