| scholarly article | Q13442814 |
| P356 | DOI | 10.1126/SCIENCE.286.5442.1149 |
| P698 | PubMed publication ID | 10550051 |
| P50 | author | David L. Wiest | Q41678244 |
| P2093 | author name string | Allman D | |
| Kappes DJ | |||
| Dave V | |||
| Keefe R | |||
| P433 | issue | 5442 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | cell fate commitment | Q14860192 |
| P304 | page(s) | 1149-1153 | |
| P577 | publication date | 1999-11-01 | |
| P1433 | published in | Science | Q192864 |
| P1476 | title | Regulation of lineage commitment distinct from positive selection. | |
| P478 | volume | 286 |
| Q35729215 | An alternative to current thinking about positive selection, negative selection and activation of T cells |
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| Q41763674 | Bcl11b represses a mature T-cell gene expression program in immature CD4(+)CD8(+) thymocytes |
| Q36202203 | CD4-CD8 lineage commitment: an inside view |
| Q36071442 | CD4-CD8 lineage differentiation: Thpok-ing into the nucleus |
| Q35824059 | CD4/CD8-lineage differentiation in the thymus: from nuclear effectors to membrane signals |
| Q50777703 | Cascading suppression of transcriptional silencers by ThPOK seals helper T cell fate. |
| Q33839945 | Co-receptor choice by V alpha14i NKT cells is driven by Th-POK expression rather than avoidance of CD8-mediated negative selection |
| Q36382781 | Commitment issues: linking positive selection signals and lineage diversification in the thymus |
| Q40115071 | Control of Regulatory T Cell Differentiation by the Transcription Factors Thpok and LRF. |
| Q35012095 | Controlling CD4 gene expression during T cell lineage commitment |
| Q28511459 | Critical roles for transcription factor GATA-3 in thymocyte development |
| Q24652128 | Development of all CD4 T lineages requires nuclear factor TOX |
| Q35796133 | Disregulated expression of the transcription factor ThPOK during T-cell development leads to high incidence of T-cell lymphomas |
| Q36982963 | Egr2 is required for Bcl-2 induction during positive selection |
| Q39889156 | Epigenetic propagation of CD4 expression is established by the Cd4 proximal enhancer in helper T cells. |
| Q37802426 | Expanding roles for ThPOK in thymic development |
| Q24569631 | GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation |
| Q39654957 | Identification of important regulatory region of Th-POK |
| Q64884264 | Immunology: guide for a cell-fate decision. |
| Q33529096 | Itk derived signals regulate the expression of Th-POK and controls the development of CD4 T cells |
| Q34831201 | Lineage fate and intense debate: myths, models and mechanisms of CD4- versus CD8-lineage choice |
| Q44762315 | Lipid-mediated presentation of MHC class II molecules guides thymocytes to the CD4 lineage |
| Q59792917 | Live-Cell FRET Imaging Reveals a Role of Extracellular Signal-Regulated Kinase Activity Dynamics in Thymocyte Motility |
| Q37088979 | Maintaining CD4-CD8 lineage integrity in T cells: where plasticity serves versatility |
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| Q37408424 | Soluble γc cytokine receptor suppresses IL-15 signaling and impairs iNKT cell development in the thymus |
| Q37369175 | Survival of mature T cells depends on signaling through HOIP. |
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| Q34021127 | TCR-mediated ThPOK induction promotes development of mature (CD24-) gammadelta thymocytes. |
| Q35566626 | TOX is required for development of the CD4 T cell lineage gene program |
| Q34563178 | Th inducing POZ-Kruppel Factor (ThPOK) is a key regulator of the immune response since the early steps of colorectal carcinogenesis |
| Q50114692 | Th-POK regulates mammary gland lactation through mTOR-SREBP pathway. |
| Q42220100 | ThPOK acts late in specification of the helper T cell lineage and suppresses Runx-mediated commitment to the cytotoxic T cell lineage |
| Q37415052 | ThPOK derepression is required for robust CD8 T cell responses to viral infection |
| Q38034839 | The BTB-ZF transcription factors |
| Q35769445 | The CD4/CD8 lineage choice: new insights into epigenetic regulation during T cell development |
| Q34079334 | The CD4/CD8 lineage decision: integration of signalling pathways |
| Q33780442 | The Nef-mediated AIDS-like disease of CD4C/human immunodeficiency virus transgenic mice is associated with increased Fas/FasL expression on T cells and T-cell death but is not prevented in Fas-, FasL-, tumor necrosis factor receptor 1-, or interleuk |
| Q87628572 | The ThPOK transcription factor differentially affects the development and function of self-specific CD8(+) T cells and regulatory CD4(+) T cells |
| Q36073462 | The enigma of CD4-lineage specification |
| Q37781936 | The network of transcription factors that underlie the CD4 versus CD8 lineage decision |
| Q34242695 | The role of orphan nuclear receptor in thymocyte differentiation and lymphoid organ development |
| Q36440062 | The transcription factor Th-POK negatively regulates Th17 differentiation in Vα14i NKT cells |
| Q45345537 | The transcription factor ThPOK suppresses Runx3 and imposes CD4(+) lineage fate by inducing the SOCS suppressors of cytokine signaling. |
| Q81483894 | The zinc finger protein cKrox directs CD4 lineage differentiation during intrathymic T cell positive selection |
| Q50977520 | The zinc finger transcription factor Th-POK regulates CD4 versus CD8 T-cell lineage commitment. |
| Q35064355 | Transcriptional and epigenetic networks of helper T and innate lymphoid cells. |
| Q27023639 | Transcriptional control of CD4 and CD8 coreceptor expression during T cell development |
| Q37938910 | Transcriptional control of T-cell development |
| Q34626885 | Transcriptional repressors, corepressors and chromatin modifying enzymes in T cell development |
| Q38810888 | Views on helper/cytotoxic lineage choice from a bottom-up approach |
| Q36972887 | What Happens in the Thymus Does Not Stay in the Thymus: How T Cells Recycle the CD4+-CD8+ Lineage Commitment Transcriptional Circuitry To Control Their Function |
| Q39660793 | p300-Mediated Acetylation Stabilizes the Th-Inducing POK Factor |
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