GATA-3 dominant negative mutant. Functional redundancy of the T cell receptor alpha and beta enhancers

scientific article published on January 1995

GATA-3 dominant negative mutant. Functional redundancy of the T cell receptor alpha and beta enhancers is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1074/JBC.270.4.1515
P698PubMed publication ID7829479
P5875ResearchGate publication ID240233607

P2093author name stringLee PP
Winoto A
Smith VM
Szychowski S
P2860cites workMurine and human T-lymphocyte GATA-3 factors mediate transcription through a cis-regulatory element within the human T-cell receptor delta gene enhancerQ24300369
The human enhancer-binding protein Gata3 binds to several T-cell receptor regulatory elementsQ24324104
Cloning of GT box-binding proteins: a novel Sp1 multigene family regulating T-cell receptor gene expressionQ24337872
Mouse GATA-4: a retinoic acid-inducible GATA-binding transcription factor expressed in endodermally derived tissues and heartQ24606117
Cloning of cDNA for the major DNA-binding protein of the erythroid lineage through expression in mammalian cellsQ29620250
Activity and tissue-specific expression of the transcription factor NF-E1 multigene familyQ34267803
A T-cell-specific transcriptional enhancer element 3' of C alpha in the human T-cell receptor alpha locusQ34301580
The erythroid-specific transcription factor Eryf1: a new finger proteinQ34543086
Regulation of transcription of the human T cell antigen receptor delta chain gene. A T lineage-specific enhancer element is located in the J delta 3-C delta intronQ36350171
Functional GATA-3 binding sites within murine CD8 alpha upstream regulatory sequencesQ36362299
Two essential regulatory elements in the human interferon gamma promoter confer activation specific expression in T cellsQ36362494
Elf-1 binds to a critical element in a second CD4 enhancerQ36666636
Distinct roles for the two cGATA-1 finger domainsQ36703387
Complex regulation of the immunoglobulin mu heavy-chain gene enhancer: microB, a new determinant of enhancer functionQ36711797
Involvement of a second lymphoid-specific enhancer element in the regulation of immunoglobulin heavy-chain gene expression.Q36711826
Regulation of the human T-cell receptor alpha gene enhancer: multiple ubiquitous and T-cell-specific nuclear proteins interact with four hypomethylated enhancer elementsQ36724081
Identification and functional characterization of the human T-cell receptor beta gene transcriptional enhancer: common nuclear proteins interact with the transcriptional regulatory elements of the T-cell receptor alpha and beta genesQ36729503
Regulated expression of globin chains and the erythroid transcription factor GATA-1 during erythropoiesis in the developing mouseQ36775117
Immunoglobulin gene transcriptionQ37357879
Identification of a T-cell-specific transcriptional enhancer located 3' of C gamma 1 in the murine T-cell receptor gamma locusQ37385878
Identification of a T-cell-specific enhancer at the locus encoding T-cell antigen receptor gamma chainQ37429467
GATA elements are necessary for the activity and tissue specificity of the T-cell receptor beta-chain transcriptional enhancerQ38307421
Human GATA-3 trans-activation, DNA-binding, and nuclear localization activities are organized into distinct structural domainsQ38310615
Identification and characterization of an Alu-containing, T-cell-specific enhancer located in the last intron of the human CD8 alpha geneQ38314503
Transcriptional activation and DNA binding by the erythroid factor GF-1/NF-E1/Eryf 1.Q38338431
Transcriptional regulation of T cell receptor genesQ40898227
Expression of GATA-3 during lymphocyte differentiation and mouse embryogenesisQ41650230
A T cell-specific transcriptional enhancer within the human T cell receptor delta locusQ41740688
DNA-binding specificity of GATA family transcription factorsQ42078566
A transcriptional enhancer of the mouse T cell receptor δ gene locusQ67898370
A transcriptional enhancer 3' of C beta 2 in the T cell receptor beta locusQ70057416
P433issue4
P407language of work or nameEnglishQ1860
P304page(s)1515-1520
P577publication date1995-01-01
P1433published inJournal of Biological ChemistryQ867727
P1476titleGATA-3 dominant negative mutant. Functional redundancy of the T cell receptor alpha and beta enhancers
P478volume270

Reverse relations

cites work (P2860)
Q53458849A T-cell-specific CD154 transcriptional enhancer located just upstream of the promoter.
Q24312921Abundant expression of Kallikrein 1 gene in human keratinocytes was mediated by GATA3
Q40370630Acetylation of GATA-3 affects T-cell survival and homing to secondary lymphoid organs
Q35176320CD154 transcriptional regulation in primary human CD4 T cells
Q33761216Ectopic T cell receptor-α locus control region activity in B cells is suppressed by direct linkage to two flanking genes at once
Q43159934FIP1L1-PDGFRalpha imposes eosinophil lineage commitment on hematopoietic stem/progenitor cells
Q38356159GATA factors are essential for activity of the neuron-specific enhancer of the gonadotropin-releasing hormone gene
Q46044258GATA-3 expression is controlled by TCR signals and regulates CD4/CD8 differentiation
Q35834668GATA-3 induces T helper cell type 2 (Th2) cytokine expression and chromatin remodeling in committed Th1 cells
Q24569631GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation
Q27341203Genomic analysis of the function of the transcription factor gata3 during development of the mammalian inner ear
Q24314811Identification and cloning of the G3B cDNA encoding a 3′ segment of a protein binding to GATA-3
Q61357092Inhibition of Th1 Development Mediated by GATA-3 through an IL-4-Independent Mechanism
Q28511275Inhibition of allergic inflammation in a murine model of asthma by expression of a dominant-negative mutant of GATA-3
Q24676765Interaction of GATA-3/T-bet transcription factors regulates expression of sialyl Lewis X homing receptors on Th1/Th2 lymphocytes
Q52532456Involvement of the N-finger in the self-association of GATA-1.
Q33607430Molecular regulation of cytokine gene expression during the immune response
Q34347579Mutation of GATA3 in human breast tumors
Q24522833TAL1 and LIM-only proteins synergistically induce retinaldehyde dehydrogenase 2 expression in T-cell acute lymphoblastic leukemia by acting as cofactors for GATA3
Q28302912Transcriptional activity of TAL1 in T cell acute lymphoblastic leukemia (T-ALL) requires RBTN1 or -2 and induces TALLA1, a highly specific tumor marker of T-ALL

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