| review article | Q7318358 |
| scholarly article | Q13442814 |
| P356 | DOI | 10.1038/NRI2488 |
| P698 | PubMed publication ID | 19165228 |
| P50 | author | Richard Flavell | Q2149481 |
| P2093 | author name string | Derk Amsen | |
| Andrey Antov | |||
| P2860 | cites work | Differential effects of Notch ligands Delta-1 and Jagged-1 in human lymphoid differentiation | Q24291744 |
| Notch1 augments NF-kappaB activity by facilitating its nuclear retention | Q24297567 | ||
| Notch3 and pre-TCR interaction unveils distinct NF-kappaB pathways in T-cell development and leukemia. | Q24305527 | ||
| Binding of Delta1, Jagged1, and Jagged2 to Notch2 rapidly induces cleavage, nuclear translocation, and hyperphosphorylation of Notch2 | Q24550771 | ||
| Notch signaling: cell fate control and signal integration in development | Q27861061 | ||
| Cutting edge: Identification of an alternative GATA-3 promoter directing tissue-specific gene expression in mouse and human | Q28215575 | ||
| Essential role of Stat6 in IL-4 signalling | Q28276199 | ||
| Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene | Q28276209 | ||
| Activation of c-Kit in dendritic cells regulates T helper cell differentiation and allergic asthma | Q28584858 | ||
| IL-4 inhibits TGF-beta-induced Foxp3+ T cells and, together with TGF-beta, generates IL-9+ IL-10+ Foxp3(-) effector T cells | Q28590243 | ||
| Notch directly regulates Gata3 expression during T helper 2 cell differentiation | Q28594834 | ||
| Direct regulation of Gata3 expression determines the T helper differentiation potential of Notch | Q28594879 | ||
| F3/contactin acts as a functional ligand for Notch during oligodendrocyte maturation | Q28646270 | ||
| Notch signalling: a simple pathway becomes complex | Q29555851 | ||
| IL-17 family cytokines and the expanding diversity of effector T cell lineages | Q29619361 | ||
| Functional diversity of helper T lymphocytes | Q29619415 | ||
| Notch and presenilin regulate cellular expansion and cytokine secretion but cannot instruct Th1/Th2 fate acquisition | Q33356044 | ||
| Intramembrane proteolysis: theme and variations. | Q34342964 | ||
| Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells | Q34388169 | ||
| Target selectivity of vertebrate notch proteins. Collaboration between discrete domains and CSL-binding site architecture determines activation probability | Q34478018 | ||
| Mastermind-like transcriptional co-activators: emerging roles in regulating cross talk among multiple signaling pathways. | Q34817672 | ||
| Regulation of dendritic-cell differentiation by bone marrow stroma via different Notch ligands | Q35578604 | ||
| Dendritic-cell control of pathogen-driven T-cell polarization | Q35597117 | ||
| Turning it up a Notch: cross-talk between TGF beta and Notch signaling | Q36017991 | ||
| Type 2 immunity is controlled by IL-4/IL-13 expression in hematopoietic non-eosinophil cells of the innate immune system | Q36228614 | ||
| Notch ligand Delta-like 4 regulates disease pathogenesis during respiratory viral infections by modulating Th2 cytokines | Q36229204 | ||
| CD8- DCs induce IL-12-independent Th1 differentiation through Delta 4 Notch-like ligand in response to bacterial LPS | Q36229524 | ||
| CD4(+)CD25(-)Foxp3(-) Th1 cells are the source of IL-10-mediated immune suppression in chronic cutaneous leishmaniasis | Q36229713 | ||
| Conventional T-bet(+)Foxp3(-) Th1 cells are the major source of host-protective regulatory IL-10 during intracellular protozoan infection. | Q36229731 | ||
| A signal transducer and activator of transcription (Stat)4-independent pathway for the development of T helper type 1 cells | Q36401785 | ||
| Notch signaling is an important regulator of type 2 immunity. | Q36403646 | ||
| Notch regulates IL-10 production by T helper 1 cells | Q36491342 | ||
| Essential role of Notch signaling in effector memory CD8+ T cell-mediated airway hyperresponsiveness and inflammation. | Q36639992 | ||
| Notch1 and TGFbeta1 cooperatively regulate Foxp3 expression and the maintenance of peripheral regulatory T cells | Q36843721 | ||
| T follicular helper (TFH) cells in normal and dysregulated immune responses | Q37049341 | ||
| Selected Toll-like receptor agonist combinations synergistically trigger a T helper type 1-polarizing program in dendritic cells | Q37139993 | ||
| Induction and effector functions of T(H)17 cells. | Q37194494 | ||
| The many facets of Notch ligands | Q37256458 | ||
| Functional conservation of mouse Notch receptor family members | Q38352139 | ||
| Stat6 regulation of in vivo IL-4 responses | Q39529330 | ||
| NF-kappaB2 is a putative target gene of activated Notch-1 via RBP-Jkappa | Q39631069 | ||
| Notch-1 associates with IKKalpha and regulates IKK activity in cervical cancer cells. | Q39971503 | ||
| Induction of antigen-specific regulatory T cells following overexpression of a Notch ligand by human B lymphocytes | Q39997530 | ||
| Acinetobacter lwoffii and Lactococcus lactis strains isolated from farm cowsheds possess strong allergy-protective properties | Q40137010 | ||
| Targeting the NF-kappaB signaling pathway in Notch1-induced T-cell leukemia. | Q40195204 | ||
| Notch 1 signaling regulates peripheral T cell activation | Q40566978 | ||
| Th2 differentiation is unaffected by Jagged2 expression on dendritic cells | Q41875479 | ||
| Suppression of Th2 cell development by Notch ligands Delta1 and Delta4 | Q41962999 | ||
| Treg-mediated immunosuppression involves activation of the Notch-HES1 axis by membrane-bound TGF-beta | Q42001733 | ||
| Jagged2-expressing hematopoietic progenitors promote regulatory T cell expansion in the periphery through notch signaling | Q42602502 | ||
| MyD88-mediated instructive signals in dendritic cells regulate pulmonary immune responses during respiratory virus infection | Q44165845 | ||
| Mice lacking IL-12 develop polarized Th1 cells during viral infection | Q44244442 | ||
| Host-dependent type 1 cytokine responses driven by inactivated viruses may fail to default in the absence of IL-12 or IFN-alpha/beta | Q44456708 | ||
| TCR-mediated Notch signaling regulates proliferation and IFN-gamma production in peripheral T cells | Q44576462 | ||
| Expression of activated Notch3 in transgenic mice enhances generation of T regulatory cells and protects against experimental autoimmune diabetes | Q44625248 | ||
| Partial loss of presenilins causes seborrheic keratosis and autoimmune disease in mice | Q44884968 | ||
| In the absence of IL-12, CD4(+) T cell responses to intracellular pathogens fail to default to a Th2 pattern and are host protective in an IL-10(-/-) setting | Q45069275 | ||
| Overexpression of the Notch ligand, Jagged-1, induces alloantigen-specific human regulatory T cells | Q45863413 | ||
| A notch-independent activity of suppressor of hairless is required for normal mechanoreceptor physiology | Q46703801 | ||
| Delta1-Notch3 interactions bias the functional differentiation of activated CD4+ T cells | Q47438852 | ||
| Regulation of alphabeta/gammadelta T cell lineage commitment and peripheral T cell responses by Notch/RBP-J signaling | Q47607371 | ||
| Instruction of distinct CD4 T helper cell fates by different notch ligands on antigen-presenting cells | Q47619638 | ||
| Notch signaling augments T cell responsiveness by enhancing CD25 expression | Q47640384 | ||
| NB-3/Notch1 pathway via Deltex1 promotes neural progenitor cell differentiation into oligodendrocytes | Q47769650 | ||
| The interleukin-4 enhancer CNS-2 is regulated by Notch signals and controls initial expression in NKT cells and memory-type CD4 T cells. | Q50726643 | ||
| Role of T-bet in commitment of TH1 cells before IL-12-dependent selection. | Q51065721 | ||
| Stat6-independent GATA-3 autoactivation directs IL-4-independent Th2 development and commitment. | Q51083007 | ||
| Accumulation of effector CD4 T cells during type 2 immune responses is negatively regulated by Stat6. | Q51968180 | ||
| Feedback regulation is central to Delta-Notch signalling required for Drosophila wing vein morphogenesis. | Q52192649 | ||
| Transforming growth factor-beta 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9-producing subset. | Q53446140 | ||
| Dendritic cell expression of the Notch ligandjagged2 is not essential for Th2 response inductionin vivo | Q56880711 | ||
| Inflammatory mediators are insufficient for full dendritic cell activation and promote expansion of CD4+ T cell populations lacking helper function | Q56880717 | ||
| Human immature myeloid dendritic cells trigger a TH2-polarizing program via Jagged-1/Notch interaction | Q61759284 | ||
| IL-12-deficient mice are defective in IFN gamma production and type 1 cytokine responses | Q71079171 | ||
| A critical role for NF-kappa B in GATA3 expression and TH2 differentiation in allergic airway inflammation | Q73339834 | ||
| Serrate1-induced notch signalling regulates the decision between immunity and tolerance made by peripheral CD4(+) T cells | Q73399528 | ||
| Single cell analysis reveals that IL-4 receptor/Stat6 signaling is not required for the in vivo or in vitro development of CD4+ lymphocytes with a Th2 cytokine profile | Q73520544 | ||
| Specificity of sn50 for NF-kappa B? | Q73933988 | ||
| Endotoxin can induce MyD88-deficient dendritic cells to support T(h)2 cell differentiation | Q74405327 | ||
| Toll-like receptors control activation of adaptive immune responses | Q74486847 | ||
| A 3' enhancer in the IL-4 gene regulates cytokine production by Th2 cells and mast cells | Q74548143 | ||
| Notch-1 regulates NF-kappaB activity in hemopoietic progenitor cells | Q74601849 | ||
| IL-12 is dispensable for innate and adaptive immunity against low doses of Listeria monocytogenes | Q77378930 | ||
| IL-12 is not required for induction of type 1 cytokine responses in viral infections | Q77899649 | ||
| Pancreas-infiltrating Th1 cells and diabetes develop in IL-12-deficient nonobese diabetic mice | Q78145332 | ||
| Off the beaten pathway: the complex cross talk between Notch and NF-kappaB | Q80146628 | ||
| Notch3 inhibition in myelin-reactive T cells down-regulates protein kinase C theta and attenuates experimental autoimmune encephalomyelitis | Q80633672 | ||
| JAGGED1 and delta1 differentially regulate the outcome of experimental autoimmune encephalomyelitis | Q81464305 | ||
| Inhibitors of gamma-secretase block in vivo and in vitro T helper type 1 polarization by preventing Notch upregulation of Tbx21 | Q95814547 | ||
| P433 | issue | 2 | |
| P921 | main subject | cell differentiation | Q210861 |
| P304 | page(s) | 116-124 | |
| P577 | publication date | 2009-02-01 | |
| P1433 | published in | Nature Reviews Immunology | Q43355 |
| P1476 | title | The different faces of Notch in T-helper-cell differentiation | |
| P478 | volume | 9 |
| Q34768853 | Alternative promoter usage at the Notch1 locus supports ligand-independent signaling in T cell development and leukemogenesis. |
| Q35180702 | An overview of notch signaling in adult tissue renewal and maintenance |
| Q47807019 | Anti-Jagged Immunotherapy Inhibits MDSCs and Overcomes Tumor-Induced Tolerance. |
| Q52316983 | Attenuated Notch signaling in schizophrenia and bipolar disorder. |
| Q37762225 | Basophils are potent antigen-presenting cells that selectively induce Th2 cells |
| Q52560201 | Bcl11b is essential for licensing Th2 differentiation during helminth infection and allergic asthma. |
| Q53368019 | Biological therapy induces expression changes in Notch pathway in psoriasis. |
| Q36733439 | Blockade of individual Notch ligands and receptors controls graft-versus-host disease |
| Q47770493 | Bone marrow transplant-induced alterations in Notch signaling promote pathologic Th17 responses to γ-herpesvirus infection. |
| Q36544872 | Bortezomib enhances expression of effector molecules in anti-tumor CD8+ T lymphocytes by promoting Notch-nuclear factor-κB crosstalk |
| Q35360046 | CD4 T-cell transcriptome analysis reveals aberrant regulation of STAT3 and Wnt signaling pathways in rheumatoid arthritis: evidence from a case-control study |
| Q40477823 | Cleavage of Notch1 by granzyme B disables its transcriptional activity. |
| Q37901573 | Co-ordination of incoming and outgoing traffic in antigen-presenting cells by pattern recognition receptors and T cells |
| Q36199919 | Control of peripheral tolerance by regulatory T cell-intrinsic Notch signaling. |
| Q38919640 | CpG in Combination with an Inhibitor of Notch Signaling Suppresses Formalin-Inactivated Respiratory Syncytial Virus-Enhanced Airway Hyperresponsiveness and Inflammation by Inhibiting Th17 Memory Responses and Promoting Tissue-Resident Memory Cells i |
| Q38957582 | DLL4+ dendritic cells: Key regulators of Notch Signaling in effector T cell responses |
| Q34577734 | Defective IL-10 signaling in hyper-IgE syndrome results in impaired generation of tolerogenic dendritic cells and induced regulatory T cells. |
| Q36717891 | Delta-like ligand 4 identifies a previously uncharacterized population of inflammatory dendritic cells that plays important roles in eliciting allogeneic T cell responses in mice |
| Q61803781 | Dendritic Cell Regulation of Graft-Vs.-Host Disease: Immunostimulation and Tolerance |
| Q34015306 | Dendritic cell c-kit signaling and adaptive immunity: implications for the upper airways |
| Q64085682 | Determinant roles of dendritic cell-expressed Notch Delta-like and Jagged ligands on anti-tumor T cell immunity |
| Q35089039 | Development of a unique epigenetic signature during in vivo Th17 differentiation |
| Q37590222 | Diesel exhaust particle-treated human bronchial epithelial cells upregulate Jagged-1 and OX40 ligand in myeloid dendritic cells via thymic stromal lymphopoietin |
| Q51646353 | Different profiles of notch signaling in cigarette smoke-induced pulmonary emphysema and bleomycin-induced pulmonary fibrosis. |
| Q93108507 | Effects of Moxibustion and Moxa Smoke on Behavior Changes and Energy Metabolism in APP/PS1 Mice |
| Q54442995 | Expression analysis of Notch-related molecules in peripheral blood T helper cells of patients with rheumatoid arthritis. |
| Q85370236 | Expression levels of Notch1 and Delta-like 4 in peripheral lymphocytes and their relationship with T helper 17 (Th17) cells in renal transplant recipients |
| Q36163412 | Ferulic Acid Induces Th1 Responses by Modulating the Function of Dendritic Cells and Ameliorates Th2-Mediated Allergic Airway Inflammation in Mice |
| Q43184369 | Functional and Phenotypic Plasticity of CD4(+) T Cell Subsets |
| Q38803570 | Future perspectives: therapeutic targeting of notch signalling may become a strategy in patients receiving stem cell transplantation for hematologic malignancies |
| Q24569631 | GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation |
| Q38133656 | Histone methyltransferase and histone methylation in inflammatory T-cell responses |
| Q50918353 | Histone modifications of Notch1 promoter affect lung CD4+ T cell differentiation in asthmatic rats. |
| Q42031458 | Human stem/progenitor cells from bone marrow enhance glial differentiation of rat neural stem cells: a role for transforming growth factor β and Notch signaling |
| Q57796939 | ILC-poiesis: Ensuring tissue ILC differentiation at the right place and time |
| Q38889051 | Immunogenomics of gastrointestinal nematode infection in ruminants - breeding for resistance to produce food sustainably and safely |
| Q37523472 | Inhibition of Notch signaling prevents experimental fibrosis and induces regression of established fibrosis. |
| Q39292313 | Innate Control of Adaptive Immunity: Beyond the Three-Signal Paradigm. |
| Q33515881 | Integrating extrinsic and intrinsic cues into a minimal model of lineage commitment for hematopoietic progenitors |
| Q35980526 | Involvement of Notch signaling pathway in regulating IL-12 expression via c-Rel in activated macrophages |
| Q36905544 | Jagged2 acts as a Delta-like Notch ligand during early hematopoietic cell fate decisions |
| Q86485270 | Jagged2-signaling promotes IL-6-dependent transplant rejection |
| Q91810683 | Magnolol exerts anti-asthmatic effects by regulating Janus kinase-signal transduction and activation of transcription and Notch signaling pathways and modulating Th1/Th2/Th17 cytokines in ovalbumin-sensitized asthmatic mice |
| Q37509047 | Mechanisms of tolerance and allergic sensitization in the airways and the lungs. |
| Q36252614 | Microbial heat shock protein 65 attenuates airway hyperresponsiveness and inflammation by modulating the function of dendritic cells |
| Q35918324 | Mind bomb-1 in dendritic cells is specifically required for Notch-mediated T helper type 2 differentiation |
| Q42699781 | Modulation of Signal Strength Switches Notch from an Inducer of T Cells to an Inducer of ILC2. |
| Q26795618 | Modulatory effects of bortezomib on host immune cell functions |
| Q91993914 | Multi-Faceted Notch in Allergic Airway Inflammation |
| Q36296504 | Multivalent Forms of the Notch Ligand DLL-1 Enhance Antitumor T-cell Immunity in Lung Cancer and Improve Efficacy of EGFR-Targeted Therapy |
| Q58789958 | NOTCH and Graft-Versus-Host Disease |
| Q46706247 | Nicotine exposure alters the mRNA expression of Notch ligands in dendritic cells and their response to Th1-/Th2-promoting stimuli |
| Q39274325 | Notch Signaling in T Helper Cell Subsets: Instructor or Unbiased Amplifier? |
| Q54309935 | Notch activation on effector T cells increases their sensitivity to Treg cell-mediated suppression through upregulation of TGF-βRII expression. |
| Q37952793 | Notch and inflammatory T-cell response: new developments and challenges |
| Q39116742 | Notch as a tumour suppressor. |
| Q41602132 | Notch controls the survival of memory CD4+ T cells by regulating glucose uptake |
| Q35848780 | Notch ligand delta-like 4 blockade alleviates experimental autoimmune encephalomyelitis by promoting regulatory T cell development |
| Q27320168 | Notch ligand delta-like 4-pretreated dendritic cells alleviate allergic airway responses by enhancing IL-10 production |
| Q51369795 | Notch pathway plays a novel and critical role in regulating responses of T and antigen-presenting cells in aGVHD. |
| Q36609701 | Notch receptors and Smad3 signaling cooperate in the induction of interleukin-9-producing T cells |
| Q37325713 | Notch signaling in hematopoietic cell transplantation and T cell alloimmunity. |
| Q38845270 | Notch signaling in lung diseases: focus on Notch1 and Notch3. |
| Q37594765 | Notch signaling in the hematopoietic system |
| Q34568892 | Notch signaling is a critical regulator of allogeneic CD4+ T-cell responses mediating graft-versus-host disease. |
| Q37075692 | Notch signaling regulates T cell accumulation and function in the central nervous system during experimental autoimmune encephalomyelitis. |
| Q54379266 | Notch signaling regulates the development of a novel type of Thy1-expressing dendritic cell in the thymus. |
| Q87842237 | Notch signaling represents an important checkpoint between follicular T-helper and canonical T-helper 2 cell fate |
| Q37146430 | Notch simultaneously orchestrates multiple helper T cell programs independently of cytokine signals. |
| Q36055999 | Notch system in the linkage of innate and adaptive immunity |
| Q41993883 | Notch-mediated conversion of activated T cells into stem cell memory-like T cells for adoptive immunotherapy. |
| Q37173575 | RBPJ Controls Development of Pathogenic Th17 Cells by Regulating IL-23 Receptor Expression |
| Q64067672 | Rbpj expression in regulatory T cells is critical for restraining T2 responses |
| Q34186971 | Redundant Notch1 and Notch2 signaling is necessary for IFNγ secretion by T helper 1 cells during infection with Leishmania major |
| Q38979322 | Regulation of Interleukin-10 Expression |
| Q38105858 | Regulation of innate and adaptive immunity by Notch |
| Q34574231 | Regulatory T cells in many flavors control asthma |
| Q34017104 | Rescue of notch-1 signaling in antigen-specific CD8+ T cells overcomes tumor-induced T-cell suppression and enhances immunotherapy in cancer |
| Q36939870 | Rheumatoid arthritis-associated RBPJ polymorphism alters memory CD4+ T cells |
| Q38615145 | Role of CSL-dependent and independent Notch signaling pathways in cell apoptosis |
| Q27001202 | STAT6-dependent and -independent mechanisms in Th2 polarization |
| Q26767443 | Signaling in T cells - is anything the m(a)TOR with the picture(s)? |
| Q36811035 | Signaling of c-kit in dendritic cells influences adaptive immunity |
| Q37669790 | T helper 17 cells: discovery, function, and physiological trigger |
| Q33637184 | Temporal induction of immunoregulatory processes coincides with age-dependent resistance to viral-induced type 1 diabetes |
| Q39008798 | Th9 cells in the pathogenesis of EAE and multiple sclerosis |
| Q24301407 | The CD46-Jagged1 interaction is critical for human TH1 immunity |
| Q35657090 | The Expression of Notch/Notch Ligand, IL-35, IL-17, and Th17/Treg in Preeclampsia |
| Q42439250 | The Notch Ligand DLL4 Defines a Capability of Human Dendritic Cells in Regulating Th1 and Th17 Differentiation. |
| Q34071370 | The critical role of Notch ligand Delta-like 1 in the pathogenesis of influenza A virus (H1N1) infection |
| Q91640081 | The emerging role of ADAM metalloproteinases in immunity |
| Q33747604 | The female lower genital tract is a privileged compartment with IL-10 producing dendritic cells and poor Th1 immunity following Chlamydia trachomatis infection |
| Q36576209 | The linkage of innate and adaptive immune response during granulomatous development |
| Q37027292 | Transcription Factor KLF2 in Dendritic Cells Downregulates Th2 Programming via the HIF-1α/Jagged2/Notch Axis |
| Q48158819 | Transcription factor RBP-J-mediated signalling regulates basophil immunoregulatory function in mouse asthma model. |
| Q37938910 | Transcriptional control of T-cell development |
| Q35164666 | Transient blockade of delta-like Notch ligands prevents allograft rejection mediated by cellular and humoral mechanisms in a mouse model of heart transplantation. |
| Q35931425 | Vehicular exhaust particles promote allergic airway inflammation through an aryl hydrocarbon receptor-notch signaling cascade |
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