scholarly article | Q13442814 |
P50 | author | Paul J van Diest | Q85899264 |
P2093 | author name string | Jan Meeldijk | |
Marc Vooijs | |||
Niels Bovenschen | |||
Geert van Tetering | |||
P2860 | cites work | Notch inhibits apoptosis by direct interference with XIAP ubiquitination and degradation | Q24298097 |
Intracellular cleavage of Notch leads to a heterodimeric receptor on the plasma membrane | Q24321237 | ||
Human homologs of a Drosophila Enhancer of split gene product define a novel family of nuclear proteins | Q24324093 | ||
Perforin-independent extracellular granzyme B activity contributes to abdominal aortic aneurysm | Q24645335 | ||
The Notch1 receptor is cleaved constitutively by a furin-like convertase | Q24671866 | ||
Mastermind mediates chromatin-specific transcription and turnover of the Notch enhancer complex | Q24675233 | ||
Structural basis for autoinhibition of Notch | Q27644319 | ||
Structural basis for proteolytic specificity of the human apoptosis-inducing granzyme M | Q27656093 | ||
A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain | Q28141707 | ||
The Anti-apoptotic Effect of Notch-1 Requires p56 -dependent, Akt/PKB-mediated Signaling in T Cells | Q28212977 | ||
Extracellular granzymes A and B in humans: detection of native species during CTL responses in vitro and in vivo | Q28266759 | ||
Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain | Q28273268 | ||
Physical interaction between a novel domain of the receptor Notch and the transcription factor RBP-J kappa/Su(H) | Q28286560 | ||
The canonical Notch signaling pathway: unfolding the activation mechanism | Q29547725 | ||
Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia | Q29614269 | ||
A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis | Q29617776 | ||
Granzyme B proteolyzes receptors important to proliferation and survival, tipping the balance toward apoptosis | Q33247896 | ||
Essential roles for ankyrin repeat and transactivation domains in induction of T-cell leukemia by notch1. | Q33965862 | ||
Notch interferes with the scaffold function of JNK-interacting protein 1 to inhibit the JNK signaling pathway | Q34063426 | ||
Cytotoxic and non-cytotoxic roles of the CTL/NK protease granzyme B. | Q34120058 | ||
Crystal structure of the CSL-Notch-Mastermind ternary complex bound to DNA. | Q34501252 | ||
Death by a thousand cuts: granzyme pathways of programmed cell death | Q34588821 | ||
Metalloprotease ADAM10 is required for Notch1 site 2 cleavage. | Q35000965 | ||
Activated Notch1 inhibits p53-induced apoptosis and sustains transformation by human papillomavirus type 16 E6 and E7 oncogenes through a PI3K-PKB/Akt-dependent pathway | Q35020680 | ||
Notch regulates cytolytic effector function in CD8+ T cells. | Q35219642 | ||
Extracellular granzymes: current perspectives | Q36567777 | ||
The different faces of Notch in T-helper-cell differentiation | Q37376021 | ||
Signal transduction by activated mNotch: importance of proteolytic processing and its regulation by the extracellular domain. | Q37724159 | ||
Orphan granzymes find a home | Q37763995 | ||
Roles of the ankyrin repeats and C-terminal region of the mouse notch1 intracellular region | Q39725752 | ||
Notch activation induces Akt signaling via an autocrine loop to prevent apoptosis in breast epithelial cells. | Q39843637 | ||
Active and zymogen forms of granzyme B are constitutively released from cytotoxic lymphocytes in the absence of target cell engagement. | Q39905527 | ||
Leukemia-associated mutations within the NOTCH1 heterodimerization domain fall into at least two distinct mechanistic classes | Q40273258 | ||
Cell binding, internalization and cytotoxic activity of human granzyme B expressed in the yeast Pichia pastoris | Q40342409 | ||
Ligand-induced signaling in the absence of furin processing of Notch1. | Q40833238 | ||
Involvement of RBP-J in biological functions of mouse Notch1 and its derivatives. | Q41078359 | ||
Benzyloxycarbonyl-Val-Ala-Asp (OMe) fluoromethylketone (Z-VAD.FMK) inhibits apoptosis by blocking the processing of CPP32. | Q42981625 | ||
Granzyme K displays highly restricted substrate specificity that only partially overlaps with granzyme A. | Q46211971 | ||
NK cell protease granzyme M targets alpha-tubulin and disorganizes the microtubule network | Q46560058 | ||
lag-1, a gene required for lin-12 and glp-1 signaling in Caenorhabditis elegans, is homologous to human CBF1 and Drosophila Su(H). | Q47069543 | ||
The suppressor of hairless protein participates in notch receptor signaling | Q47072502 | ||
Down-regulation of Notch-1 contributes to cell growth inhibition and apoptosis in pancreatic cancer cells. | Q53631737 | ||
Osmotic swelling of phospholipid vesicles causes them to fuse with a planar phospholipid bilayer membrane | Q72934239 | ||
Nuclear translocation of granzyme B in target cell apoptosis | Q73540343 | ||
A ligand-induced extracellular cleavage regulates gamma-secretase-like proteolytic activation of Notch1 | Q73958442 | ||
The levels of soluble granzyme A and B are elevated in plasma and synovial fluid of patients with rheumatoid arthritis (RA) | Q77774922 | ||
Granzyme B is critical for T cell receptor-induced cell death of type 2 helper T cells | Q80092770 | ||
Suppression of p53 by Notch in lymphomagenesis: implications for initiation and regression | Q81066571 | ||
Survival signaling by Notch1: mammalian target of rapamycin (mTOR)-dependent inhibition of p53 | Q83228672 | ||
P433 | issue | 2 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 313-322 | |
P577 | publication date | 2011-07-01 | |
P1433 | published in | Biochemical Journal | Q864221 |
P1476 | title | Cleavage of Notch1 by granzyme B disables its transcriptional activity. | |
P478 | volume | 437 |
Q37103319 | High NOTCH activity induces radiation resistance in non small cell lung cancer |
Q36779384 | IL-21-stimulated human plasmacytoid dendritic cells secrete granzyme B, which impairs their capacity to induce T-cell proliferation |
Q33569831 | Improved HSC reconstitution and protection from inflammatory stress and chemotherapy in mice lacking granzyme B. |
Q35595880 | Nonapoptotic and extracellular activity of granzyme B mediates resistance to regulatory T cell (Treg) suppression by HLA-DR-CD25hiCD127lo Tregs in multiple sclerosis and in response to IL-6. |
Q38993482 | Regulated proteolysis of NOTCH2 and NOTCH3 receptors by ADAM10 and presenilins |