IL-4 inhibits TGF-beta-induced Foxp3+ T cells and, together with TGF-beta, generates IL-9+ IL-10+ Foxp3(-) effector T cells

scientific journal article

IL-4 inhibits TGF-beta-induced Foxp3+ T cells and, together with TGF-beta, generates IL-9+ IL-10+ Foxp3(-) effector T cells is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/NI.1677
P3181OpenCitations bibliographic resource ID2198139
P932PMC publication ID2999006
P698PubMed publication ID18997793
P5875ResearchGate publication ID232791245

P50authorSamia J. KhouryQ37372486
Raymond A SobelQ87841746
Vijay KuchrooQ87889159
P2093author name stringAmit Awasthi
Mohamed Oukka
Terry B Strom
Valérie Dardalhon
Wassim Elyaman
Wenda Gao
I-Cheng Ho
George Galileos
Meike Mitsdoerffer
Hyoung Kwon
P2860cites workA novel transcription factor, T-bet, directs Th1 lineage commitmentQ22253874
TGF-beta-induced Foxp3 inhibits T(H)17 cell differentiation by antagonizing RORgammat functionQ24314628
The biological functions of T helper 17 cell effector cytokines in inflammationQ24614431
Essential role for CD103 in the T cell-mediated regulation of experimental colitisQ24646106
Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3Q24672849
Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammationQ24676080
Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cellsQ27860460
Control of regulatory T cell development by the transcription factor Foxp3Q27860489
The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cellsQ27860620
Expression of interleukin-10 in intestinal lymphocytes detected by an interleukin-10 reporter knockin tiger mouseQ28589701
The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cellsQ29614226
GATA3-driven Th2 responses inhibit TGF-beta1-induced FOXP3 expression and the formation of regulatory T cells.Q33312509
Th17 cells: effector T cells with inflammatory propertiesQ33732092
A defect in interleukin-10 leads to enhanced malarial disease in Plasmodium chabaudi chabaudi infection in miceQ34001680
Stat6 and IRS-2 cooperate in interleukin 4 (IL-4)-induced proliferation and differentiation but are dispensable for IL-4-dependent rescue from apoptosisQ34290627
In vivo instruction of suppressor commitment in naive T cellsQ34548023
Mast cells are essential intermediaries in regulatory T-cell toleranceQ34559099
Regulatory T cell-derived interleukin-10 limits inflammation at environmental interfacesQ34590015
IL-10-producing T cells suppress immune responses in anergic tuberculosis patientsQ35159232
Control of autoimmunity by naturally arising regulatory CD4+ T cellsQ35623006
IL-10 is necessary for the expression of airway hyperresponsiveness but not pulmonary inflammation after allergic sensitizationQ35757072
Antagonistic nature of T helper 1/2 developmental programs in opposing peripheral induction of Foxp3+ regulatory T cellsQ36156864
Role of interleukin 10 in the B lymphocyte hyperactivity and autoantibody production of human systemic lupus erythematosusQ36364479
Tr1 cells: from discovery to their clinical application.Q36390028
Expression of interleukin 9 in the lungs of transgenic mice causes airway inflammation, mast cell hyperplasia, and bronchial hyperresponsivenessQ36401550
T cells that cannot respond to TGF-beta escape control by CD4(+)CD25(+) regulatory T cellsQ36402737
Regulatory T cells suppress systemic and mucosal immune activation to control intestinal inflammationQ36563545
Contextual regulation of inflammation: a duet by transforming growth factor-beta and interleukin-10.Q37133445
Induction and effector functions of T(H)17 cells.Q37194494
Pulmonary overexpression of IL-9 induces Th2 cytokine expression, leading to immune pathologyQ39737356
Cloning and characterization of a cDNA for a new mouse T cell growth factor (P40)Q41915051
Continuous administration of anti-interleukin 10 antibodies delays onset of autoimmunity in NZB/W F1 miceQ42942093
IL-10 inhibits parasite killing and nitrogen oxide production by IFN-gamma-activated macrophagesQ44173170
IFN-alpha induces the human IL-10 gene by recruiting both IFN regulatory factor 1 and Stat3.Q47817002
Regulation of T helper cell differentiation by STAT moleculesQ47841624
IL-4 induces allergic-like inflammatory disease and alters T cell development in transgenic mice.Q54710076
A dominant function for interleukin 27 in generating interleukin 10-producing anti-inflammatory T cells.Q55045567
Interleukins 27 and 6 induce STAT3-mediated T cell production of interleukin 10Q56930023
Interleukin-9 is involved in host protective immunity to intestinal nematode infectionQ57194408
Regulatory T-cell functions are subverted and converted owing to attenuated Foxp3 expressionQ59048389
Characterization of Foxp3+CD4+CD25+ and IL-10-Secreting CD4+CD25+ T Cells during Cure of ColitisQ61779891
Cytokine control of parasite-specific anergy in human urinary schistosomiasis. IL-10 modulates lymphocyte reactivityQ71120550
Restoration of IFN-gamma production and lymphocyte proliferation in visceral leishmaniasisQ72526875
IL-10 and the dangers of immune polarization: excessive type 1 and type 2 cytokine responses induce distinct forms of lethal immunopathology in murine schistosomiasisQ73869153
Inducing and expanding regulatory T cell populations by foreign antigenQ81392563
P2507corrigendum / erratumErratum: IL-4 inhibits TGF-β-induced Foxp3+ T cells and, together with TGF-β, generates IL-9+ Foxp3− effector T cellsQ57083585
P433issue12
P407language of work or nameEnglishQ1860
P921main subjectForkhead box P3Q14865673
Interleukin 4Q14865947
Interleukin 9Q14874546
Interleukin 5Q14877652
Interleukin 13Q14878305
Transforming growth factor, beta 1Q14904616
Signal transducer and activator of transcription 6Q14914616
Interferon gammaQ21494550
Interleukin 17AQ21495876
GATA binding protein 3Q21497809
Tumor necrosis factorQ21992447
P304page(s)1347-1355
P577publication date2008-11-09
P1433published inNature ImmunologyQ1071725
P1476titleIL-4 inhibits TGF-beta-induced Foxp3+ T cells and, together with TGF-beta, generates IL-9+ IL-10+ Foxp3(-) effector T cells
P478volume9

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Q36639988Interleukin-9 is required for allergic airway inflammation mediated by the cytokine TSLP.
Q37776749Interleukin‐9 as a T helper type 17 cytokine
Q37245208Interruption of dendritic cell-mediated TIM-4 signaling induces regulatory T cells and promotes skin allograft survival
Q37600191Intestinal effector T cells in health and disease.
Q55259683Intraperitoneal administration of the anti-IL-23 antibody prevents the establishment of intestinal nematodes in mice.
Q34555643Involvement of IL-9 in Th17-associated inflammation and angiogenesis of psoriasis
Q42846660Isolation and expansion of human natural T regulatory cells for cellular therapy
Q36661584Itk is required for Th9 differentiation via TCR-mediated induction of IL-2 and IRF4
Q90591179JAK-STAT pathway targeting for the treatment of inflammatory bowel disease
Q89613150Janus or Hydra: The Many Faces of T Helper Cells in the Human Tumour Microenvironment
Q33853966KLF2 is a rate-limiting transcription factor that can be targeted to enhance regulatory T-cell production
Q42383187Leptin Enhances TH2 and ILC2 Responses in Allergic Airway Disease.
Q55279342Leptin Promotes Allergic Airway Inflammation through Targeting the Unfolded Protein Response Pathway.
Q34489206Lineage-specific Effects of 1,25-Dihydroxyvitamin D3 on the Development of Effector CD4 T Cells
Q48108959Long-term effects: Galectin-1 and specific immunotherapy for allergic responses in the intestine
Q35850380Malignancies in HIV/AIDS: from epidemiology to therapeutic challenges
Q84742904Mast cells
Q41196294Mechanisms of allergen-specific immunotherapy and immune tolerance to allergens
Q29027397Mechanisms of peripheral tolerance to allergens
Q37509047Mechanisms of tolerance and allergic sensitization in the airways and the lungs.
Q27687830Mechanisms underlying helper T-cell plasticity: implications for immune-mediated disease
Q34412837Mechanistic target of rapamycin complex 1 expands Th17 and IL-4+ CD4-CD8- double-negative T cells and contracts regulatory T cells in systemic lupus erythematosus
Q52761834Messenger RNA Sequencing of Rare Cell Populations in the Lung and Lung-Draining Lymph Nodes.
Q92569677Metabolic regulation of TH17 cells
Q47701375MiR-125a targets effector programs to stabilize Treg-mediated immune homeostasis
Q51712811MicroRNAs regulate T-cell production of interleukin-9 and identify hypoxia-inducible factor-2α as an important regulator of T helper 9 and regulatory T-cell differentiation.
Q30483471Models of autoimmune demyelination in the central nervous system: on the way to translational medicine
Q56975174Modulation of regulatory T cell-Th17 balance by plasmacytoid dendritic cells
Q38203185Molecular biology of atopic dermatitis
Q30433245Much Ado about Adenosine: Adenosine Synthesis and Function in Regulatory T Cell Biology
Q37765944Multi-tasking of helper T cells
Q34356927Murine Th9 cells promote the survival of myeloid dendritic cells in cancer immunotherapy
Q35880106Mutated major histocompatibility complex class II transactivator up-regulates interleukin-33-dependent differentiation of Th2 subset through Nod2 binding for NLR (NOD-like receptor) signaling initiation
Q36102757Mycobacterium vaccae Nebulization Can Protect against Asthma in Balb/c Mice by Regulating Th9 Expression
Q37071542N-3-(oxododecanoyl)-L-homoserine lactone promotes the induction of regulatory T-cells by preventing human dendritic cell maturation
Q34993986NFIL3/E4BP4 controls type 2 T helper cell cytokine expression
Q34076106Natural Foxp3(+) regulatory T cells inhibit Th2 polarization but are biased toward suppression of Th17-driven lung inflammation
Q33609040Neutralization of Interleukin-9 Decreasing Mast Cells Infiltration in Experimental Autoimmune Encephalomyelitis
Q37621244New insights into the differentiation and function of T follicular helper cells.
Q33623326New insights into the regulation of T cells by gamma(c) family cytokines
Q38799600New insights into the role of T cells in pathogenesis of psoriasis and psoriatic arthritis
Q39442990New perspectives on the regulation of type II inflammation in asthma
Q84743158Nine lives for TH9s?
Q37292800Nine lives: plasticity among T helper cell subsets
Q34037524Nitric oxide enhances Th9 cell differentiation and airway inflammation
Q35041388Nitric oxide modulates TGF-beta-directive signals to suppress Foxp3+ regulatory T cell differentiation and potentiate Th1 development
Q42786561Nonredundant roles of IL-10 and TGF-β in suppression of immune responses to hepatic AAV-factor IX gene transfer
Q36609701Notch receptors and Smad3 signaling cooperate in the induction of interleukin-9-producing T cells
Q55380934Novel strategies in immunotherapy for allergic diseases.
Q35939766Nuclear factor of activated T cells 1 (NFAT1)-induced permissive chromatin modification facilitates nuclear factor-κB (NF-κB)-mediated interleukin-9 (IL-9) transactivation
Q37249618OX40 signaling favors the induction of T(H)9 cells and airway inflammation
Q48351328Old and New Lymphocyte Players in Inflammatory Bowel Disease
Q33561651Once a Treg, always a Treg?
Q37628032Opposing actions of IL-2 and IL-21 on Th9 differentiation correlate with their differential regulation of BCL6 expression
Q47701540Orchestration of epithelial-derived cytokines and innate immune cells in allergic airway inflammation.
Q33753888Organization of proximal signal initiation at the TCR:CD3 complex
Q33752778Overcoming the hurdles in using mouse genetic models that block TGF-beta signaling
Q37027348PLZF(+) Innate T Cells Support the TGF-β-Dependent Generation of Activated/Memory-Like Regulatory T Cells
Q38665573Pathogenic T cell subsets in allergic and chronic inflammatory bowel disorders
Q34285649Peripheral CD4+ T-cell differentiation regulated by networks of cytokines and transcription factors.
Q42333747Peripheral blood Th9 cells are a possible pharmacodynamic biomarker of nivolumab treatment efficacy in metastatic melanoma patients
Q41549282Peripheral blood Th9 cells reconstitution and its relationship with acute graft-versus-host disease after matched-sibling peripheral blood hematopoietic stem cell transplantation
Q37832385Phenotypical and functional specialization of FOXP3+ regulatory T cells
Q40169229Physical attraction of Th9 cells is skin deep
Q37509592Plasticity of CD4(+) FoxP3(+) T cells
Q38310232Plasticity of human CD4 T cell subsets
Q36702429Plasticity within the αβ⁺CD4⁺ T-cell lineage: when, how and what for?
Q85759300Possible pathogenic role of T helper type 9 cells and interleukin (IL)-9 in atopic dermatitis
Q92879746Potential Mechanisms of T Cell-Mediated and Eosinophil-Independent Bronchial Hyperresponsiveness
Q37021660Potential roles of IL-9 in the pathogenesis of systemic lupus erythematosus
Q35523670Predisposition to the development of IL-9-secreting T cells in atopic infants
Q36837356Programmed cell death ligand 2 regulates TH9 differentiation and induction of chronic airway hyperreactivity
Q41075955Programmed death one homolog maintains the pool size of regulatory T cells by promoting their differentiation and stability
Q38053810Prospects and challenges of using chicken cytokines in disease prevention
Q97070167Proteome analysis revealed the essential functions of protein phosphatase PP2A in the induction of Th9 cells
Q36315992Pulmonary Epithelial Cell-Derived Cytokine TGF-β1 Is a Critical Cofactor for Enhanced Innate Lymphoid Cell Function
Q37987044RORγt-dependent IL-17A-producing cells in the pathogenesis of intestinal inflammation
Q31132719Rapamycin resistant murine th9 cells have a stable in vivo phenotype and inhibit graft-versus-host reactivity
Q40204242Reciprocal regulation of the Il9 locus by counteracting activities of transcription factors IRF1 and IRF4.
Q50507569Recombinant DNA immunotherapy ameliorate established airway allergy in a IL-10 dependent pathway.
Q43429271Recruitment and phenotypic characteristics of interleukin 9-producing CD4+ T cells in malignant pleural effusion
Q47845996Reducing the Levels of Akt Activation by PDK1 Knock-in Mutation Protects Neuronal Cultures against Synthetic Amyloid-Beta Peptides
Q37849438Regulating Il9 transcription in T helper cells
Q36713986Regulation of Foxp3+ inducible regulatory T cell stability by SOCS2
Q33682703Regulation of IL-9 expression by IL-25 signaling.
Q38979322Regulation of Interleukin-10 Expression
Q38004975Regulation of T helper cell differentiation by interferon regulatory factor family members
Q38035601Regulation of TGFβ in the immune system: an emerging role for integrins and dendritic cells.
Q34953484Regulation of human Th9 differentiation by type I interferons and IL-21
Q38105858Regulation of innate and adaptive immunity by Notch
Q37802427Regulation of the Ifng locus in the context of T-lineage specification and plasticity.
Q39097028Regulation of the Immune Response by TGF-β: From Conception to Autoimmunity and Infection
Q33860019Regulation of the T helper cell type 2 (Th2)/T regulatory cell (Treg) balance by IL-4 and STAT6
Q35196374Regulatory T cell reprogramming toward a Th2-cell-like lineage impairs oral tolerance and promotes food allergy
Q36064548Regulatory T cells in asthma
Q38620803Regulatory T cells in atherosclerosis: critical immune regulatory function and therapeutic potential.
Q37728843Regulatory T cells: immune suppression and beyond
Q48115866Resolution of inflammation by interleukin-9-producing type 2 innate lymphoid cells
Q37801396Responding to infection and apoptosis — a task for TH17 cells
Q36224502Resveratrol analogue HS-1793 induces the modulation of tumor-derived T cells
Q41283266Retinoic acid hypersensitivity promotes peripheral tolerance in recent thymic emigrants
Q24601213Robust tumor immunity to melanoma mediated by interleukin-9-producing T cells
Q39157106Role of ATP as a Key Signaling Molecule Mediating Radiation-Induced Biological Effects
Q37773234Role of CD4+ cytotoxic T lymphocytes in the control of viral diseases and cancer
Q38187410Role of IL-9 and STATs in hematological malignancies (Review).
Q37729059Role of T cells in graft rejection and transplantation tolerance.
Q37053851Role of Th17 cells in the pathogenesis of CNS inflammatory demyelination
Q34023371Role of Tyk-2 in Th9 and Th17 cells in allergic asthma
Q90225030Role of Zinc in Immune System and Anti-Cancer Defense Mechanisms
Q38076482SMAD regulatory networks construct a balanced immune system
Q39121162STAT5 and CD4 + T Cell Immunity.
Q100307068STAT5 promotes accessibility and is required for BATF-mediated plasticity at the Il9 locus
Q37076055STAT6 controls the number of regulatory T cells in vivo, thereby regulating allergic lung inflammation
Q35114346STAT6 expression in multiple cell types mediates the cooperative development of allergic airway disease
Q35685708STAT6-dependent regulation of Th9 development
Q49909082Selective autophagy restricts IL-9 secretion from TH9 cells: relevance in cancer growth
Q41701341Selective degradation of PU.1 during autophagy represses the differentiation and antitumour activity of TH9 cells
Q37809744Shaping the T-cell repertoire in the periphery
Q57054689Signal transducer and activator of transcription 4 limits the development of adaptive regulatory T cells
Q26778375Single-cell technologies to study the immune system
Q34742199Sirtuin-1 targeting promotes Foxp3+ T-regulatory cell function and prolongs allograft survival.
Q37414801Skin inflammation arising from cutaneous regulatory T cell deficiency leads to impaired viral immune responses.
Q47643463Specifically differentiated T cell subset promotes tumor immunity over fatal immunity.
Q85167476Synergistic Effect of IL-6 and IL-4 in Driving Fate Revision of Natural Foxp3+ Regulatory T Cells
Q34793513T Cell Activation and Proinflammatory Cytokine Production in Clinically Cured Tuberculosis Are Time-Dependent and Accompanied by Upregulation of IL-10.
Q47576343T Cell Receptor and Co-Stimulatory Signals for Th9 Generation
Q26823613T Cells: Soldiers and Spies--The Surveillance and Control of Effector T Cells by Regulatory T Cells
Q92634783T Helper 9 Cells: A New Player in Immune-Related Diseases
Q38245734T Helper Cells Fate Mapping by Co-stimulatory Molecules and its Functions in Allograft Rejection and Tolerance
Q89860707T Helper Cells: The Modulators of Inflammation in Multiple Sclerosis
Q28081582T Helper Lymphocyte Subsets and Plasticity in Autoimmunity and Cancer: An Overview
Q90055083T Lymphocyte-Mediated Liver Immunopathology of Schistosomiasis
Q42727084T cell responses: naive to memory and everything in between
Q35558638T cell subsets and their signature cytokines in autoimmune and inflammatory diseases
Q38134677T helper cells plasticity in inflammation.
Q34180508T regulatory cells control antigen-induced recruitment of mast cell progenitors to the lungs of C57BL/6 mice
Q36109798T(H)2 heterogeneity: Does function follow form?
Q37891668T-bet in disease.
Q33723154T-cell based immunotherapy in experimental autoimmune encephalomyelitis and multiple sclerosis
Q37902883T-helper cells in the etiopathogenesis of periodontal disease: A mini review
Q33999342TGF-beta and 'adaptive' Foxp3(+) regulatory T cells
Q37316137TGF-beta can leave you breathless
Q34113303TGF-beta induces IL-9 production from human Th17 cells.
Q33566661TGF-β activation and function in immunity
Q39408352TGF-β and Th17 Cells Related Injuries in Patients with Sulfur Mustard Exposure.
Q35903214TGF-β converts apoptotic stimuli into the signal for Th9 differentiation
Q36458347TGF-β in tolerance, development and regulation of immunity
Q92480505TGF-β induces ST2 and programs ILC2 development
Q42702792TGF-β induces the expression of the adaptor Ndfip1 to silence IL-4 production during iTreg cell differentiation
Q84389025TGF-β interactions with IL-1 family members trigger IL-4-independent IL-9 production by mouse CD4(+) T cells
Q39094862TGF-β regulation of encephalitogenic and regulatory T cells in multiple sclerosis
Q42973784TGF-β1: Mediator of a feedback loop in eosinophilic esophagitis--or should we really say mastocytic esophagitis?
Q37967132TGF-β: the sword, the wand, and the shield of FOXP3(+) regulatory T cells
Q34276027TGFβ in T cell biology and tumor immunity: Angel or devil?
Q37526777TGFβ receptor mutations impose a strong predisposition for human allergic disease
Q64103921TGFβ-activation by dendritic cells drives Th17 induction and intestinal contractility and augments the expulsion of the parasite Trichinella spiralis in mice
Q38107790TH2, allergy and group 2 innate lymphoid cells
Q37688655TH9 cell differentiation, transcriptional control and function in inflammation, autoimmune diseases and cancer.
Q37575177TH9 cells in anti-tumor immunity
Q38948052TH9 cells in skin disorders
Q56671802TH9 cells that express the transcription factor PU.1 drive T cell–mediated colitis via IL-9 receptor signaling in intestinal epithelial cells
Q54117525TIM‑4 blockade of KCs combined with exogenous TGF‑β injection helps to reverse acute rejection and prolong the survival rate of mice receiving liver allografts.
Q61800300TNF-α enhances Th9 cell differentiation and antitumor immunity via TNFR2-dependent pathways
Q35105613Tailored immune responses: novel effector helper T cell subsets in protective immunity
Q34157827Targeting ganglioside epitope 3G11 on the surface of CD4+ T cells suppresses EAE by altering the Treg/Th17 cell balance
Q89628639Targeting the IL-9 pathway in cancer immunotherapy
Q85741340Tc9 cells, a new subset of CD8(+) T cells, support Th2-mediated airway inflammation
Q33894387Th 17 cells interplay with Foxp3+ Tregs in regulation of inflammation and autoimmunity
Q34066077Th1, Th17, and Th9 effector cells induce experimental autoimmune encephalomyelitis with different pathological phenotypes
Q34146417Th17 cells demonstrate stable cytokine production in a proallergic environment
Q40594670Th2 and Th9 responses in patients with chronic mucocutaneous candidiasis and hyper-IgE syndrome
Q89909329Th2 cells as an intermediate for the differentiation of naïve T cells into Th9 cells, associated with the Smad3/Smad4 and IRF4 pathway
Q37436865Th9 Cells Drive Host Immunity against Gastrointestinal Worm Infection
Q40224197Th9 Cells and Parasitic Inflammation: Use of Nippostrongylus and Schistosoma Models
Q40224209Th9 Cells: New Member of T Helper Cell Family.
Q37552040Th9 and allergic disease
Q39011698Th9 and other IL-9-producing cells in allergic asthma
Q37259259Th9 cell development requires a BATF-regulated transcriptional network
Q91771408Th9 cells in allergic diseases: A role for the microbiota?
Q39006003Th9 cells in inflammatory bowel diseases
Q39008798Th9 cells in the pathogenesis of EAE and multiple sclerosis
Q36357944Th9 cells promote antitumor immune responses in vivo
Q40690742Th9 cells: a new population of helper T cells
Q37696777Th9 cells: differentiation and disease.
Q37700776Th9/IL-9 profile in human echinococcosis: their involvement in immune response during infection by Echinococcus granulosus
Q37835840Th9: a new player in asthma pathogenesis?
Q58764816The -> and -> in the Gene Are Associated With Viral Load and Liver Enzyme Levels in Patients With Chronic Viral Liver Diseases
Q50077079The Common Cytokine Receptor γ Chain Family of Cytokines
Q37215886The Current STATus of lymphocyte signaling: new roles for old players.
Q50566729The DNA-binding inhibitor Id3 regulates IL-9 production in CD4(+) T cells.
Q92857692The Endless Saga of Monocyte Diversity
Q87405889The Escherichia coli heat-labile enterotoxin B subunit protects from allergic airway disease development by inducing CD4+ regulatory T cells
Q58090901The Foxp3+ regulatory T-cell population requires IL-4Rα signaling to control inflammation during helminth infections
Q43246232The Immunogenicity of Branded and Biosimilar Infliximab in Rheumatoid Arthritis According to Th9-Related Responses
Q38880764The Molecular Mechanisms of Vitamin A Deficiency in Multiple Sclerosis.
Q26799454The Newly Identified T Helper 22 Cells Lodge in Leukemia
Q41948431The Other T Helper Cells in Asthma Pathogenesis
Q35680673The Profile of T Helper Subsets in Bone Marrow Microenvironment Is Distinct for Different Stages of Acute Myeloid Leukemia Patients and Chemotherapy Partly Ameliorates These Variations
Q33593742The ST2/IL-33 Axis in Immune Cells during Inflammatory Diseases
Q26799347The TNF-family cytokine TL1A: from lymphocyte costimulator to disease co-conspirator
Q41197326The TNF-family ligand TL1A and its receptor DR3 promote T cell-mediated allergic immunopathology by enhancing differentiation and pathogenicity of IL-9-producing T cells.
Q34312117The acute environment, rather than T cell subset pre-commitment, regulates expression of the human T cell cytokine amphiregulin
Q36703636The autophagy gene Atg16l1 differentially regulates Treg and TH2 cells to control intestinal inflammation.
Q37782213The cellular orchestra in skin allergy; are differences to lung and nose relevant?
Q28083375The development and in vivo function of T helper 9 cells
Q37982395The deviated balance between regulatory T cell and Th17 in autoimmunity
Q37376021The different faces of Notch in T-helper-cell differentiation
Q56607716The dual nature of TH17 cells: shifting the focus to function
Q38040749The dual roles of inflammatory cytokines and chemokines in the regulation of autoimmune diseases and their clinical implications
Q27001581The effects of TLR activation on T-cell development and differentiation
Q21131158The environment of regulatory T cell biology: cytokines, metabolites, and the microbiome
Q37106490The expression of inflammatory genes is upregulated in peripheral blood of patients with type 1 diabetes
Q38365115The immune suppressive function of transforming growth factor-β (TGF-β) in human diseases
Q26823691The immunomodulatory and neuroprotective effects of mesenchymal stem cells (MSCs) in experimental autoimmune encephalomyelitis (EAE): a model of multiple sclerosis (MS)
Q53161765The many lives of IL-9: a question of survival?
Q35490792The molecular mechanisms of Foxp3 gene regulation.
Q38023601The role of costimulatory molecules in directing the functional differentiation of alloreactive T helper cells
Q33855162The signaling suppressor CIS controls proallergic T cell development and allergic airway inflammation.
Q37988164The symphony of the ninth: the development and function of Th9 cells
Q51521238The synergistic effect of surface topography and sustained release of TGF-β1 on myogenic differentiation of human mesenchymal stem cells.
Q36470838The tick salivary protein sialostatin L inhibits the Th9-derived production of the asthma-promoting cytokine IL-9 and is effective in the prevention of experimental asthma.
Q38980079The transcription factor IRF1 dictates the IL-21-dependent anticancer functions of TH9 cells
Q35105032The transcription factor PU.1 is required for the development of IL-9-producing T cells and allergic inflammation.
Q42230758The transcription factor Sox4 is a downstream target of signaling by the cytokine TGF-β and suppresses T(H)2 differentiation
Q41470945The transcription factor musculin promotes the unidirectional development of peripheral Treg cells by suppressing the TH2 transcriptional program
Q39006000The transcription factor network in Th9 cells
Q37830196The unexpected link between infection-induced apoptosis and a TH17 immune response.
Q35973941The unique features of Th9 cells and their products
Q37567423Therapeutic manipulation of immune tolerance in allergic disease
Q41635365Therapeutic potential of adipose stem cell-derived conditioned medium against pulmonary hypertension and lung fibrosis.
Q39161228Thrombospondin immune regulation and the kidney
Q86008535Thymic stromal lymphopoietin-induced interleukin-17A is involved in the development of IgE-mediated atopic dermatitis-like skin lesions in mice
Q37511971Trans-presentation of IL-6 by dendritic cells is required for the priming of pathogenic TH17 cells
Q40224202Transcription Factor Binding Studies in CD4+ T Cells: siRNA Transfection, Chromatin Immunoprecipitation, and Liquid Luminescent DNA Precipitation Assay
Q50669352Transcription Factors Downstream of IL-4 and TGF-β Signals: Analysis by Quantitative PCR, Western Blot, and Flow Cytometry.
Q42266549Transcription factor Foxo1 is essential for IL-9 induction in T helper cells
Q55280345Transcriptional Control of Th9 Cells: Role of Foxo1 in Interleukin-9 Induction.
Q35064355Transcriptional and epigenetic networks of helper T and innate lymphoid cells.
Q37858466Transcriptional regulation by STAT6.
Q26823406Transforming growth factor-beta1 in inflammatory airway disease: a key for understanding inflammation and remodeling
Q53126400Transforming growth factor-β, interleukin-17, and IL-23 gene expression profiles associated with human peri-implantitis.
Q37780481Transgenic mouse models of multiple sclerosis
Q37632472Translational mini-review series on Th17 cells: CD4 T helper cells: functional plasticity and differential sensitivity to regulatory T cell-mediated regulation
Q91526449Treg expression of CIS suppresses allergic airway inflammation through antagonizing an autonomous TH2 program
Q56474910Tregs in immunotherapy: opportunities and challenges
Q38530619Tumor necrosis factor receptor- associated factor 6 (TRAF6) regulation of development, function, and homeostasis of the immune system
Q38868314Tumor-specific Th2 responses inhibit growth of CT26 colon-cancer cells in mice via converting intratumor regulatory T cells to Th9 cells
Q35226496Type 1 regulatory T cells (Tr1) in autoimmunity
Q50558366Unlike αβ T cells, γδ T cells, LTi cells and NKT cells do not require IRF4 for the production of IL-17A and IL-22.
Q40104447Up-regulation of transient receptor potential vanilloid (TRPV) and down-regulation of brain-derived neurotrophic factor (BDNF) expression in patients with functional dyspepsia (FD).
Q34610624Vaccination strategies to promote mucosal antibody responses.
Q92128397What's old is new again: Batf transcription factors and Th9 cells
Q52689973When worlds collide: Th17 and Treg cells in cancer and autoimmunity.
Q61808840Yangyin Qingre Huoxue Method in Traditional Chinese Medicine Ameliorates Atherosclerosis in ApoE Mice Suffering from High-Fat Diet and HSP65 Aggression
Q42333675Yoking OX40 to regulation of IL-9.
Q53638799[Effector T cells].
Q84542814[Th9 cells. Functionally important or just an epiphenomenon?]
Q95642020miR-145 Inhibits Th9 Cell Differentiation by Suppressing Activation of the PI3K/Akt/mTOR/p70S6K/HIF-1α Pathway in Malignant Ascites from Liver Cancer
Q90189626ncRNAs in Type-2 Immunity
Q35807045p-STAT6, PU.1, and NF-κB are involved in allergen-induced late-phase airway inflammation in asthma patients
Q49545801α4β7+ CD4+ effector/effector memory T cells differentiate into productively and latently infected central memory T cells by TGFβ1 during HIV-1 infection.
Q34434443γδ T cells enhance autoimmunity by restraining regulatory T cell responses via an interleukin-23-dependent mechanism.

Q57083585Erratum: IL-4 inhibits TGF-β-induced Foxp3+ T cells and, together with TGF-β, generates IL-9+ Foxp3− effector T cellsmain subjectP921

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