T Cell Activation and Proinflammatory Cytokine Production in Clinically Cured Tuberculosis Are Time-Dependent and Accompanied by Upregulation of IL-10.

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T Cell Activation and Proinflammatory Cytokine Production in Clinically Cured Tuberculosis Are Time-Dependent and Accompanied by Upregulation of IL-10. is …
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scholarly articleQ13442814

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P819ADS bibcode2013PLoSO...865492S
P356DOI10.1371/JOURNAL.PONE.0065492
P8608Fatcat IDrelease_7evzz4qax5ggpdvn3hjz2mjct4
P932PMC publication ID3688829
P698PubMed publication ID23824716
P5875ResearchGate publication ID245028951

P50authorLúcio R CastellanoQ75839793
P2093author name stringVirmondes Rodrigues
Juliana R Machado
Rafael F Oliveira
Marcos Vinícius da Silva
Denise B R Rodrigues
Sanívia A L Pereira
Amanda A Figueiredo
Gladstone E L Faria
Patricia B D Alexandre
P2860cites workCutting edge: CD8+CD122+ regulatory T cells produce IL-10 to suppress IFN-gamma production and proliferation of CD8+ T cells.Q51316721
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IL-10 is required to prevent immune hyperactivity during infection with Trypanosoma cruziQ58843169
T cell activation via Leu-23 (CD69)Q69212672
Differential spontaneous expression of mRNA for IL-4, IL-10, IL-13, IL-2 and interferon-gamma (IFN-gamma) in peripheral blood mononuclear cells (PBMC) from atopic patientsQ70909111
T cell-derived IL-10 antagonizes macrophage function in mycobacterial infectionQ71929941
Rapid flow cytometric method for measuring lymphocyte subset activationQ72034591
IL-10 is required for prevention of necrosis in the small intestine and mortality in both genetically resistant BALB/c and susceptible C57BL/6 mice following peroral infection with Toxoplasma gondiiQ73755946
Differential effects of TNF and LTalpha in the host defense against M. bovis BCGQ74122559
High spontaneous IL-10 production in unrelated bone marrow transplant recipients is associated with fewer transplant-related complications and early deathsQ77925510
Serum cytokine concentrations do not parallel Mycobacterium tuberculosis-induced cytokine production in patients with tuberculosisQ78687288
Adherence influences monocyte responsiveness to interleukin-10Q78785499
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T(H)1 cells control themselves by producing interleukin-10.Q36831662
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Th1-Th2 polarisation and autophagy in the control of intracellular mycobacteria by macrophages.Q37463450
Decreased IFN- gamma and increased IL-4 production by human CD8(+) T cells in response to Mycobacterium tuberculosis in tuberculosis patientsQ39473484
Monocyte cytokine secretion in patients with pulmonary tuberculosis differs from that of healthy infected subjects and correlates with clinical manifestationsQ40541640
The activation antigen CD69.Q40558412
Reprogramming of IL-10 activity and signaling by IFN-gamma.Q40618355
Positive tuberculin test and risk of infection by Mycobacterium tuberculosis in a tuberculosis clinic settled in an upright building, in Minas Gerais, BrazilQ42280376
Novel human immunodeficiencies reveal the essential role of type-I cytokines in immunity to intracellular bacteriaQ43487749
Mice incapable of making IL-4 or IL-10 display normal resistance to infection with Mycobacterium tuberculosisQ44390333
Interferon-gamma-treated murine macrophages inhibit growth of tubercle bacilli via the generation of reactive nitrogen intermediatesQ44828688
Mycobacterium tuberculosis induces high production of nitric oxide in coordination with production of tumour necrosis factor-alpha in patients with fresh active tuberculosis but not in MDR tuberculosisQ45000171
Natural T, gammadelta, and NK cells in mycobacterial, Salmonella, and human immunodeficiency virus infectionsQ45741366
Th1/Th2 immune responses are associated with active cutaneous leishmaniasis and clinical cure is associated with strong interferon-gamma production.Q47694485
Reactivation of tuberculosis is associated with a shift from type 1 to type 2 cytokinesQ48245059
Balance of IL-10 and interferon-gamma plasma levels in human visceral leishmaniasis: implications in the pathogenesisQ25256772
A human IFNGR1 small deletion hotspot associated with dominant susceptibility to mycobacterial infectionQ28140734
Tuberculosis associated with infliximab, a tumor necrosis factor alpha-neutralizing agentQ28191546
IL-4 inhibits TGF-beta-induced Foxp3+ T cells and, together with TGF-beta, generates IL-9+ IL-10+ Foxp3(-) effector T cellsQ28590243
Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophagesQ29547420
Immunology of tuberculosisQ29614370
Differentiation of effector CD4 T cell populations (*)Q29614838
Naturally arising CD4+ regulatory t cells for immunologic self-tolerance and negative control of immune responsesQ29619908
Effector T cells control lung inflammation during acute influenza virus infection by producing IL-10.Q30438825
Surprisingly high specificity of the PPD skin test for M. tuberculosis infection from recent exposure in The GambiaQ30828531
Dynamic changes in pro- and anti-inflammatory cytokine profiles and gamma interferon receptor signaling integrity correlate with tuberculosis disease activity and response to curative treatmentQ33265416
CD69 expression on CD4+ T lymphocytes after in vitro stimulation with tuberculin is an indicator of immune sensitization against Mycobacterium tuberculosis antigensQ33593498
Suboptimal activation of antigen-specific CD4+ effector cells enables persistence of M. tuberculosis in vivoQ33921252
Spontaneous cytokine production and its effect on induced productionQ33945317
Comparison of serum and cell-specific cytokines in humansQ33999709
Dichotomy of cytokine profiles in patients and high-risk healthy subjects exposed to tuberculosisQ34002304
Endogenous interleukin-10 is required for prevention of a hyperinflammatory intracerebral immune response in Listeria monocytogenes meningoencephalitisQ34008352
Identification of M. tuberculosis-specific Th1 cells expressing CD69 generated in vivo in pleural fluid cells from patients with tuberculous pleurisyQ34009517
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CD4+CD25+ regulatory T cells control Leishmania major persistence and immunityQ34529549
TGF-beta and IL-6 drive the production of IL-17 and IL-10 by T cells and restrain T(H)-17 cell-mediated pathologyQ34712326
T-cell cytokine responses in human infection with Mycobacterium tuberculosisQ35433339
Regulation of neutrophils by interferon-γ limits lung inflammation during tuberculosis infectionQ35441389
Absence of a prominent Th2 cytokine response in human tuberculosisQ35483311
Production of interleukin-10 and transforming growth factor beta by peripheral blood mononuclear cells in Q fever endocarditisQ35523970
IL-17 and IFN-γ expression in lymphocytes from patients with active tuberculosis correlates with the severity of the diseaseQ35988589
CD4+ T cell-dependent IFN-γ production by CD8+ effector T cells in Mycobacterium tuberculosis infectionQ36179457
Infected site-restricted Foxp3+ natural regulatory T cells are specific for microbial antigensQ36228356
Conventional T-bet(+)Foxp3(-) Th1 cells are the major source of host-protective regulatory IL-10 during intracellular protozoan infection.Q36229731
Human T cell activation. III. Rapid induction of a phosphorylated 28 kD/32 kD disulfide-linked early activation antigen (EA 1) by 12-o-tetradecanoyl phorbol-13-acetate, mitogens, and antigensQ36353203
Secreted lymphotoxin-alpha is essential for the control of an intracellular bacterial infection.Q36369043
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue6
P407language of work or nameEnglishQ1860
P921main subjecttuberculosisQ12204
P304page(s)e65492
P577publication date2013-06-18
P1433published inPLOS OneQ564954
P1476titleT Cell Activation and Proinflammatory Cytokine Production in Clinically Cured Tuberculosis Are Time-Dependent and Accompanied by Upregulation of IL-10
P478volume8

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cites work (P2860)
Q64239886Asthma and atopy prevalence are not reduced among former tuberculosis patients compared with controls in Lima, Peru
Q26779956Complexity and Controversies over the Cytokine Profiles of T Helper Cell Subpopulations in Tuberculosis
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Q40602539Evaluation of IL-2, IL-10, IL-17 and IP-10 as potent discriminative markers for active tuberculosis among pulmonary tuberculosis suspects
Q40524081Expression pattern of transcription factors and intracellular cytokines reveals that clinically cured tuberculosis is accompanied by an increase in Mycobacterium-specific Th1, Th2, and Th17 cells.
Q91811514In vitro Evidence of Human Immune Responsiveness Shows the Improved Potential of a Recombinant BCG Strain for Bladder Cancer Treatment
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Q55287141TNF-α blockade impairs in vitro tuberculous granuloma formation and down modulate Th1, Th17 and Treg cytokines.
Q40683257Unraveling methylation changes of host macrophages in Mycobacterium tuberculosis infection.

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