| scholarly article | Q13442814 |
| P50 | author | Andrew L. Kung | Q38544548 |
| Alejandro Villarino | Q43171336 | ||
| P2093 | author name string | D M Livingston | |
| S Y Yang | |||
| H W Lee | |||
| T P Yao | |||
| S L Reiner | |||
| N Cereb | |||
| A S Hutchins | |||
| A C Mullen | |||
| F A High | |||
| P433 | issue | 5523 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 1907-1910 | |
| P577 | publication date | 2001-06-01 | |
| P1433 | published in | Science | Q192864 |
| P1476 | title | Role of T-bet in commitment of TH1 cells before IL-12-dependent selection | |
| P478 | volume | 292 |
| Q34467924 | A Call to Arms: The Cytokine Selection Service |
| Q79273999 | A Distal Enhancer in the Interferon-γ (IFN-γ) Locus Revealed by Genome Sequence Comparison |
| Q44158836 | A Virtual Culture of CD4+ T Lymphocytes |
| Q44433415 | A continuous T-bet expression is required to silence the interleukin-4-producing potential in T helper type 1 cells |
| Q42090258 | A crucial role for T-bet in selectin ligand expression in T helper 1 (Th1) cells |
| Q37286978 | A genome-wide association study of atopic dermatitis identifies loci with overlapping effects on asthma and psoriasis |
| Q41968701 | A method for the generation of standardized qualitative dynamical systems of regulatory networks |
| Q47614392 | A novel polymorphic GATA site in the human IL-12Rbeta2 promoter region affects transcriptional activity |
| Q34304146 | A simple theoretical framework for understanding heterogeneous differentiation of CD4+ T cells. |
| Q36229330 | A subset of dendritic cells induces CD4+ T cells to produce IFN-gamma by an IL-12-independent but CD70-dependent mechanism in vivo. |
| Q41355686 | APC targeting enhances immunogenicity of a novel multistage Fc-fusion tuberculosis vaccine in mice. |
| Q47202508 | Abnormal Savda syndrome: long-term consequences of emotional and physical stress on endocrine and immune activities in an animal model. |
| Q80787010 | Activation of retinoic acid receptor-alpha favours regulatory T cell induction at the expense of IL-17-secreting T helper cell differentiation |
| Q38321775 | Alpha-toxin is produced by skin colonizing Staphylococcus aureus and induces a T helper type 1 response in atopic dermatitis |
| Q35164202 | An epigenetic view of helper T cell differentiation |
| Q40180245 | An inducible enhancer required for Il12b promoter activity in an insulated chromatin environment |
| Q42739331 | Anomalous type 17 response to viral infection by CD8+ T cells lacking T-bet and eomesodermin. |
| Q36156864 | Antagonistic nature of T helper 1/2 developmental programs in opposing peripheral induction of Foxp3+ regulatory T cells |
| Q42945025 | Anti-proliferative Activity of T-bet |
| Q95319571 | Antigen presentation by dendritic cells and their instruction of CD4+ T helper cell responses |
| Q35982511 | Application of Long-term cultured Interferon-γ Enzyme-linked Immunospot Assay for Assessing Effector and Memory T Cell Responses in Cattle |
| Q42182185 | Artesunate inhibits proliferation of naïve CD4(+) T cells but enhances function of effector T cells |
| Q41181715 | ArtinM Mediates Murine T Cell Activation and Induces Cell Death in Jurkat Human Leukemic T Cells. |
| Q37253957 | Asthma: T-bet--a master controller? |
| Q37728902 | Astragaloside II triggers T cell activation through regulation of CD45 protein tyrosine phosphatase activity |
| Q82269020 | Autoimmunity: increasing suspects in the CD4+ T cell lineup |
| Q37418406 | Biochemical signaling pathways for memory T cell recall |
| Q90365182 | Biological and clinical significance of T helper 17 cell plasticity |
| Q93147779 | CD5 on dendritic cells regulates CD4+ and CD8+ T cell activation and induction of immune responses |
| Q82388008 | CD8(+) T cells in facioscapulohumeral muscular dystrophy patients with inflammatory features at muscle MRI |
| Q35816448 | CD8(+)IL-17(+) T Cells Mediate Neutrophilic Airway Obliteration in T-bet-Deficient Mouse Lung Allograft Recipients |
| Q37259506 | CD8+ Th17 mediate costimulation blockade-resistant allograft rejection in T-bet-deficient mice |
| Q56901422 | CTLA-4 regulates allergen response by modulating GATA-3 protein level per cell |
| Q37333899 | CXCR3 deficiency increases susceptibility to genital herpes simplex virus type 2 infection: Uncoupling of CD8+ T-cell effector function but not migration |
| Q25257479 | Ca2+-signaling in airway smooth muscle cells is altered in T-bet knock-out mice |
| Q36544053 | Cell biology of T cell activation and differentiation |
| Q51061285 | Cell cycle controlling the silencing and functioning of mammalian activators |
| Q41905990 | Characterization of an adaptive immune response in microsatellite-instable colorectal cancer |
| Q24797282 | Chitosan IFN-gamma-pDNA Nanoparticle (CIN) Therapy for Allergic Asthma |
| Q38990744 | Circulating CXCR5+CXCR3+PD-1lo Tfh-like cells in HIV-1 controllers with neutralizing antibody breadth |
| Q36947101 | Clinical significance of T-bet, GATA-3, and Bcl-6 transcription factor expression in bladder carcinoma. |
| Q83304588 | Clozapine inhibits Th1 cell differentiation and causes the suppression of IFN-γ production in peripheral blood mononuclear cells |
| Q50263205 | Combination of selenium-enriched green tea polysaccharides and Huo-ji polysaccharides synergistically enhances antioxidant and immune activity in mice |
| Q41976420 | Combinations of CD45 isoforms are crucial for immune function and disease |
| Q92802132 | Combined in vitro IL-12 and IL-15 stimulation promotes cellular immune response in dogs with visceral leishmaniasis |
| Q34539858 | Common gamma chain (γc) cytokines differentially potentiate TNFR family signaling in antigen-activated CD8(+) T cells |
| Q28482191 | Compound A, a dissociated glucocorticoid receptor modulator, inhibits T-bet (Th1) and induces GATA-3 (Th2) activity in immune cells |
| Q36282244 | Comprehensive epigenetic profiling identifies multiple distal regulatory elements directing transcription of the gene encoding interferon-gamma |
| Q37377041 | Contribution of IL-12R mediated feedback loop to Th1 cell differentiation |
| Q28589387 | Control of Effector CD8 + T Cell Function by the Transcription Factor Eomesodermin |
| Q57078138 | Correlation between mRNA expression of Th1/Th2 cytokines and their specific transcription factors in human helper T-cell clones |
| Q34796730 | Critical roles of c-Rel in autoimmune inflammation and helper T cell differentiation |
| Q37379915 | Crystal structure of the DNA binding domain of the transcription factor T-bet suggests simultaneous recognition of distant genome sites |
| Q37929655 | Current understanding of Th2 cell differentiation and function |
| Q24301442 | Cutting Edge: Role of IL-27/WSX-1 Signaling for Induction of T-Bet Through Activation of STAT1 During Initial Th1 Commitment |
| Q37283066 | Cutting edge: Ikaros is a regulator of Th2 cell differentiation |
| Q35150010 | Cytokines and transcription factors that regulate T helper cell differentiation: new players and new insights. |
| Q56902320 | Cytotoxic T-lymphocyte antigen-4 inhibits GATA-3 but not T-bet mRNA expression during T helper cell differentiation |
| Q24673791 | DNA methylation maintains allele-specific KIR gene expression in human natural killer cells |
| Q35064733 | DNA methylation of Th2 lineage determination genes at birth is associated with allergic outcomes in childhood |
| Q38069828 | Defining the molecular blueprint that drives CD8(+) T cell differentiation in response to infection |
| Q41697162 | Dermatophagoides pteronyssinus immunotherapy changes the T-regulatory cell activity. |
| Q38092234 | Development and Maintenance of Regulatory T cells |
| Q35769454 | Development and function of T helper 1 cells |
| Q35176416 | Development and regulation of cell-mediated immunity in experimental leishmaniasis |
| Q77476285 | Development of Spontaneous Airway Changes Consistent with Human Asthma in Mice Lacking T-bet |
| Q28215355 | Developmental expression of the T-box transcription factor T-bet/Tbx21 during mouse embryogenesis |
| Q35785549 | Differential Regulation of Primary and Memory CD8 T Cell Immune Responses by Diacylglycerol Kinases |
| Q36284475 | Differential effects of IL-12 on Tregs and non-Treg T cells: roles of IFN-γ, IL-2 and IL-2R |
| Q29614838 | Differentiation of effector CD4 T cell populations (*) |
| Q28594879 | Direct regulation of Gata3 expression determines the T helper differentiation potential of Notch |
| Q44997621 | Discrete roles for histone acetylation in human T helper 1 cell-specific gene expression |
| Q40757721 | Distinct Effects of T-bet in T H 1 Lineage Commitment and IFN-γ Production in CD4 and CD8 T Cells |
| Q52011176 | Distinct lineages of T(H)1 cells have differential capacities for memory cell generation in vivo. |
| Q37191278 | Distinct patterns of dendritic cell cytokine release stimulated by fungal beta-glucans and toll-like receptor agonists |
| Q37117559 | Distinct regulation of effector and memory T-cell differentiation. |
| Q37065735 | Do Natural T Regulatory Cells become Activated to Antigen Specific T Regulatory Cells in Transplantation and in Autoimmunity? |
| Q34230513 | Dysfunctional CD8+ T cells in hepatitis B and C are characterized by a lack of antigen-specific T-bet induction |
| Q52545197 | Dysregulation of T lymphocyte function in itchy mice: a role for Itch in TH2 differentiation |
| Q34066925 | Ectopic T-bet expression licenses dendritic cells for IL-12-independent priming of type 1 T cells in vitro. |
| Q46814702 | Effect and mechanism of ligustrazine on Th1/Th2 cytokines in a rat asthma model |
| Q34126977 | Effector T cell plasticity: flexibility in the face of changing circumstances |
| Q34465675 | Effector and memory CD8+ T cell fate coupled by T-bet and eomesodermin |
| Q36184127 | Effects of Low Molecular Weight Yeast β-Glucan on Antioxidant and Immunological Activities in Mice |
| Q54965132 | Effects of PARP-1 deficiency on Th1 and Th2 cell differentiation. |
| Q37360656 | Emergence of the Th17 pathway and its role in host defense. |
| Q37371624 | Epigenetic control of T-helper-cell differentiation |
| Q36607880 | Epigenetic regulation of IL-12-dependent T cell proliferation |
| Q34543892 | Epigenetic regulation of T cell fate and function |
| Q37536992 | Epigenetic regulation of cytokine gene expression in T lymphocytes |
| Q34590978 | Epigenetics and T-cell immunity |
| Q36403225 | Ets-1, a functional cofactor of T-bet, is essential for Th1 inflammatory responses |
| Q42525548 | Evolution of developmental functions by the Eomesodermin, T-brain-1, Tbx21 subfamily of T-box genes: insights from amphioxus |
| Q37494109 | Evolutionarily conserved sequence elements that positively regulate IFN-gamma expression in T cells |
| Q47135666 | Expression of Th1 and Th2 Cytokine and Associated Transcription Factors in Peripheral Blood Mononuclear Cells and Correlation with Disease Severity |
| Q81082199 | Expression of human pim family genes is selectively up-regulated by cytokines promoting T helper type 1, but not T helper type 2, cell differentiation |
| Q92222186 | Extracellular Vesicles in Cancer Immune Microenvironment and Cancer Immunotherapy |
| Q37081522 | Extrinsic and intrinsic regulation of early natural killer cell development |
| Q38799374 | Fcγ1 fragment of IgG1 as a powerful affinity tag in recombinant Fc-fusion proteins: immunological, biochemical and therapeutic properties. |
| Q30698666 | FcγRIIIa-Syk Co-signal Modulates CD4+ T-cell Response and Up-regulates Toll-like Receptor (TLR) Expression |
| Q35107473 | Functional Involvement of Dual Specificity Phosphatase 16 (DUSP16), a c-Jun N-terminal Kinase-specific Phosphatase, in the Regulation of T Helper Cell Differentiation |
| Q34744638 | Further checkpoints in Th1 development |
| Q36391825 | GATA-3 promotes Th2 responses through three different mechanisms: induction of Th2 cytokine production, selective growth of Th2 cells and inhibition of Th1 cell-specific factors |
| Q73153297 | GATA-3 suppresses Th1 development by downregulation of Stat4 and not through effects on IL-12Rbeta2 chain or T-bet |
| Q37754742 | Gene expression patterns and susceptibility to allergic responses. |
| Q40714185 | Gene silencing quantitatively controls the function of a developmental trans-activator |
| Q52005548 | Genetic Reprogramming of Primary Human T Cells Reveals Functional Plasticity in Th Cell Differentiation |
| Q37498951 | Genetic and epigenetic networks controlling T helper 1 cell differentiation. |
| Q34062170 | Genetic diversity in cytokines associated with immune variation and resistance to multiple pathogens in a natural rodent population |
| Q39591718 | Genetic regulation on ex vivo differentiated natural killer cells from human umbilical cord blood CD34+ cells |
| Q47896557 | Genistein attenuated allergic airway inflammation by modulating the transcription factors T-bet, GATA-3 and STAT-6 in a murine model of asthma. |
| Q40642335 | Gingival Toll-like receptor and cytokine messenger RNA levels in equine periodontitis and oral health. |
| Q42753243 | Glucosamine Improved Atopic Dermatitis‐like Skin Lesions in NC/Nga Mice by Inhibition of Th2 Cell Development |
| Q33642117 | Goblet cell-derived resistin-like molecule beta augments CD4+ T cell production of IFN-gamma and infection-induced intestinal inflammation |
| Q50332623 | Graft-versus-host disease is independent of innate signaling pathways triggered by pathogens in host hematopoietic cells |
| Q96136568 | Graphene quantum dots as anti-inflammatory therapy for colitis |
| Q74243910 | Growth factor independent-1 induced by IL-4 regulates Th2 cell proliferation |
| Q37620249 | Gαq Regulates the Development of Rheumatoid Arthritis by Modulating Th1 Differentiation. |
| Q64266217 | HIV Infection Functionally Impairs Mycobacterium tuberculosis-Specific CD4 and CD8 T-Cell Responses |
| Q35676339 | Heat shock protein X purified from Mycobacterium tuberculosis enhances the efficacy of dendritic cells-based immunotherapy for the treatment of allergic asthma |
| Q92342000 | Helper T cell differentiation |
| Q35176407 | Helper T cell differentiation and the problem of cellular inheritance |
| Q38202009 | Helper T-cell differentiation in graft-versus-host disease after allogeneic hematopoietic stem cell transplantation |
| Q34658525 | Hematopoietic cytokines, transcription factors and lineage commitment |
| Q36202704 | Heterogeneity and cell-fate decisions in effector and memory CD8+ T cell differentiation during viral infection |
| Q38400261 | Higher numbers of T-bet+ intratumoral lymphoid cells correlate with better survival in gastric cancer |
| Q37337172 | Highly polarized Th17 cells induce EAE via a T-bet independent mechanism |
| Q33791226 | Histone acetylation at the Ifng promoter in tolerized CD4 cells is associated with increased IFN-gamma expression during subsequent immunization to the same antigen |
| Q40726351 | Hlx is induced by and genetically interacts with T-bet to promote heritable T(H)1 gene induction |
| Q37717313 | Host bone marrow-derived IL-12 enhances donor T cell engraftment in a mouse model of bone marrow transplantation |
| Q37502276 | How diverse--CD4 effector T cells and their functions |
| Q34453939 | How to Deal with Polarized Th2 Cells: Exploring the Achilles’ Heel |
| Q50959583 | Human T helper (Th) cell lineage commitment is not directly linked to the secretion of IFN-gamma or IL-4: characterization of Th cells isolated by FACS based on IFN-gamma and IL-4 secretion |
| Q42497613 | IFN-alpha is not sufficient to drive Th1 development due to lack of stable T-bet expression |
| Q34989661 | IFN-gamma-inducing transcription factor, T-bet is upregulated by estrogen in murine splenocytes: role of IL-27 but not IL-12 |
| Q51031016 | IFN-γ and IL-12 synergize to convert in vivo generated Th17 into Th1/Th17 cells |
| Q41035582 | IL-12 Influence mTOR to Modulate CD8+ T Cells Differentiation through T-bet and Eomesodermin in Response to Invasive Pulmonary Aspergillosis |
| Q37276907 | IL-12 can alleviate Th17-mediated allergic lung inflammation through induction of pulmonary IL-10 expression |
| Q37349766 | IL-12 family members in experimental colitis |
| Q81342452 | IL-12 up-regulates T-bet independently of IFN-gamma in human CD4+ T cells |
| Q36447548 | IL-12-Dependent Cytomegalovirus-Specific CD4+ T Cell Proliferation, T-bet Induction, and Effector Multifunction during Primary Infection Are Key Determinants for Early Immune Control |
| Q45422550 | IL-12-independent Th1 polarization in human mononuclear cells infected with varicella-zoster virus |
| Q37184595 | IL-12R beta 2 promotes the development of CD4+CD25+ regulatory T cells |
| Q53529589 | IL-15 exacerbates collagen-induced arthritis with an enhanced CD4+ T cell response to produce IL-17. |
| Q24629447 | IL-2 family cytokines: new insights into the complex roles of IL-2 as a broad regulator of T helper cell differentiation |
| Q34489128 | IL-23: A Cytokine That Acts on Memory T Cells |
| Q50335939 | IL-27 and IFN-αSignal via Stat1 and Stat3 and Induce T-Bet and IL-12Rβ2 in Naive T Cells |
| Q24569645 | IL-27 regulates IL-12 responsiveness of naive CD4+ T cells through Stat1-dependent and -independent mechanisms |
| Q35776074 | IRF3 deficiency impacts granzyme B expression and maintenance of memory T cell function in response to viral infection. |
| Q36007570 | Identification of a distant T-bet enhancer responsive to IL-12/Stat4 and IFNgamma/Stat1 signals. |
| Q33593953 | Ikaros silences T-bet expression and interferon-gamma production during T helper 2 differentiation |
| Q51757389 | Imbalance between T helper type 17 and T regulatory cells in patients with primary biliary cirrhosis: the serum cytokine profile and peripheral cell population |
| Q54335961 | Imbalance of Th1 and Th2 cells in cardiac injury induced by ambient fine particles |
| Q54619147 | Imbalance of Th1/Th2 transcription factors in patients with lupus nephritis. |
| Q36993451 | Immunological decision-making: how does the immune system decide to mount a helper T-cell response? |
| Q36093333 | Immunology and mathematics: crossing the divide |
| Q22241677 | Immunology of Crohn's Disease |
| Q45069275 | In the absence of IL-12, CD4(+) T cell responses to intracellular pathogens fail to default to a Th2 pattern and are host protective in an IL-10(-/-) setting |
| Q36035967 | Individual T helper cells have a quantitative cytokine memory |
| Q36369473 | Induction of cytotoxic T lymphocyte antigen 4 (CTLA-4) restricts clonal expansion of helper T cells |
| Q53590555 | Induction of maternal tolerance to fetal alloantigens by RANTES production |
| Q34976848 | Infection-Triggered Regulatory Mechanisms Override the Role of STAT 4 in Control of the Immune Response to Influenza Virus Antigens |
| Q47279406 | Inhibition of JAK-STAT Signaling Suppresses Pathogenic Immune Responses in Medium and Large Vessel Vasculitis. |
| Q51797595 | Instruction of naive CD4+ T-cell fate to T-bet expression and T helper 1 development: roles of T-cell receptor-mediated signals |
| Q28395500 | Interleukin 12 a key immunoregulatory cytokine in infection applications |
| Q29547871 | Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages |
| Q24673146 | Interleukin 21 is a T helper (Th) cell 2 cytokine that specifically inhibits the differentiation of naive Th cells into interferon gamma-producing Th1 cells |
| Q39665949 | Interleukin-12 (IL-12p70) Promotes Induction of Highly Potent Th1-Like CD4(+)CD25(+) T Regulatory Cells That Inhibit Allograft Rejection in Unmodified Recipients. |
| Q29614602 | Interleukin-12 and the regulation of innate resistance and adaptive immunity |
| Q35783782 | Interleukin-12 drives the Th1 signaling pathway in Helicobacter pylori-infected human gastric mucosa. |
| Q36494218 | Interleukin-12 to interleukin 'infinity': the rationale for future therapeutic cytokine targeting. |
| Q34452458 | Interleukin-2-inducible T cell kinase (Itk) network edge dependence for the maturation of iNKT cell |
| Q33774610 | Interleukin-6 in Allogeneic Stem Cell Transplantation: Its Possible Importance for Immunoregulation and As a Therapeutic Target |
| Q37276852 | Interplay between effector Th17 and regulatory T cells |
| Q57116002 | Intestinal Irradiation and Fibrosis in a Th1-Deficient Environment |
| Q35957480 | Intravenous tolerance effectively overcomes enhanced pro-inflammatory responses and experimental autoimmune encephalomyelitis severity in the absence of IL-12 receptor signaling |
| Q37217375 | Intrinsic and extrinsic control of effector T cell survival and memory T cell development |
| Q28592990 | Issues in T-helper 1 development--resolved and unresolved |
| Q34647024 | JAK-STAT signaling in asthma |
| Q41643177 | Janus-kinase-3-dependent signals induce chromatin remodeling at the Ifng locus during T helper 1 cell differentiation |
| Q36853486 | Kinetic analysis of genomewide gene expression reveals molecule circuitries that control T cell activation and Th1/2 differentiation |
| Q37220886 | Lactococcus lactis carrying the pValac eukaryotic expression vector coding for IL-4 reduces chemically-induced intestinal inflammation by increasing the levels of IL-10-producing regulatory cells |
| Q26828561 | Long Intergenic Non-Coding RNAs: Novel Drivers of Human Lymphocyte Differentiation |
| Q64260848 | Loss of Jak2 protects cardiac allografts from chronic rejection by attenuating Th1 response along with increased regulatory T cells |
| Q36403957 | Loss of T-bet, but not STAT1, prevents the development of experimental autoimmune encephalomyelitis |
| Q36399080 | Low dose Leishmania major promotes a transient T helper cell type 2 response that is down-regulated by interferon gamma-producing CD8+ T cells |
| Q37412380 | Lung airway-surveilling CXCR3(hi) memory CD8(+) T cells are critical for protection against influenza A virus |
| Q36077074 | Macrophage migration inhibitory factor: a downregulator of early T cell-dependent IFN-gamma responses in Plasmodium chabaudi adami (556 KA)-infected mice. |
| Q37849185 | Maternal signals for progeny prevention against allergy and asthma |
| Q39249563 | Mechanism of Action of Inhibition of Allergic Immune Responses by a Novel Antedrug TLR7 Agonist |
| Q33867509 | Mechanism of T cell hyporesponsiveness to HBcAg is associated with regulatory T cells in chronic hepatitis B |
| Q36369726 | Mechanism of transforming growth factor beta-induced inhibition of T helper type 1 differentiation |
| Q46573212 | Mechanisms altering airway smooth muscle cell Ca+ homeostasis in two asthma models |
| Q35207708 | Mechanisms of interferon-γ production by neutrophils and its function during Streptococcus pneumoniae pneumonia. |
| Q40687886 | Memory and flexibility of cytokine gene expression as separable properties of human T(H)1 and T(H)2 lymphocytes |
| Q40103848 | Memory-phenotype CD4+ T cells spontaneously generated under steady-state conditions exert innate TH1-like effector function |
| Q38872550 | Mixed Th1 and Th2 Mycobacterium tuberculosis-specific CD4 T cell responses in patients with active pulmonary tuberculosis from Tanzania |
| Q41400504 | Modular utilization of distal cis-regulatory elements controls Ifng gene expression in T cells activated by distinct stimuli |
| Q35831305 | Modulation of cytokine receptors by IL-2 broadly regulates differentiation into helper T cell lineages |
| Q37331068 | Modulation of cytokines and transcription factors (T-Bet and GATA3) in CD4 enriched cervical cells of Chlamydia trachomatis infected fertile and infertile women upon stimulation with chlamydial inclusion membrane proteins B and C. |
| Q35178738 | More than just a T-box: the role of T-bet as a possible biomarker and therapeutic target in autoimmune diseases. |
| Q46535142 | NF-kappaB activation by the viral oncoprotein StpC enhances IFN-gamma production in T cells |
| Q33281042 | NF-kappaB-regulated suppression of T-bet in T cells represses Th1 immune responses in pregnancy |
| Q46971707 | Naive CD4+ T Cells Carrying a TLR2 Agonist Overcome TGF-β-Mediated Tumor Immune Evasion. |
| Q33840153 | Naturally occurring altered peptide ligands control Salmonella-specific CD4+ T cell proliferation, IFN-gamma production, and protective potency |
| Q41095586 | New Tricks from an Old Master |
| Q36528999 | Not-so-great expectations: re-assessing the essence of T-cell memory. |
| Q33745759 | Novel Method of Monitoring Trace Cytokines and Activated STAT Molecules in the Paws of Arthritic Mice using Multiplex Bead Technology |
| Q34143892 | Nuclear role of WASp in the pathogenesis of dysregulated TH1 immunity in human Wiskott-Aldrich syndrome |
| Q38291705 | Onecut transcription factor OC2 is a direct target of T-bet in type-1 T-helper cells |
| Q37821498 | Osteopontin and allergic disease: pathophysiology and implications for diagnostics and therapy |
| Q34913467 | PPAR and immune system--what do we know? |
| Q34285649 | Peripheral CD4+ T-cell differentiation regulated by networks of cytokines and transcription factors. |
| Q51031021 | Persistence of effector memory Th1 cells is regulated by Hopx |
| Q42238387 | Phenotypic and transcriptional profile correlates with functional plasticity of antigen-specific CD4+ T cells. |
| Q43018871 | Plant-originated glycoprotein (36 kDa) suppresses interleukin-4 and -10 in bisphenol A-stimulated primary cultured mouse lymphocytes |
| Q54664979 | Polarization of Th1/Th2 in human CD4 T cells separated by CD62L: analysis by transcription factors. |
| Q38962452 | Pro- and anti-inflammatory cytokines in cutaneous leishmaniasis: a review |
| Q41341715 | Prognostic role of tumor-infiltrating lymphocytes in gastric cancer: a meta-analysis |
| Q28280634 | Proviral integration site for Moloney murine leukemia virus (PIM) kinases promote human T helper 1 cell differentiation |
| Q83503541 | RG-II from Panax ginseng C.A. Meyer suppresses asthmatic reaction |
| Q50042871 | RSK2 phosphorylates T-bet to attenuate colon cancer metastasis and growth |
| Q40080152 | Radiotherapy augments the immune response to prostate cancer in a time-dependent manner |
| Q34628368 | Rapamycin-sensitive signals control TCR/CD28-driven Ifng, Il4 and Foxp3 transcription and promoter region methylation |
| Q40064418 | Reduced generation of lung tissue-resident memory T cells during infancy. |
| Q46702165 | Reduced responsiveness of HLA-B27 transgenic rat cells to TGF-beta and IL-10-mediated regulation of IFN-gamma production |
| Q83630587 | Regulated suppression of NF-κB throughout pregnancy maintains a favourable cytokine environment necessary for pregnancy success |
| Q37592689 | Regulation of NK Cell Activation and Effector Functions by the IL-12 Family of Cytokines: The Case of IL-27. |
| Q74183099 | Regulation of T(H)1 differentiation--controlling the controllers |
| Q37382233 | Regulation of immunity at tissue sites of inflammation |
| Q28256001 | Regulation of interferon-gamma during innate and adaptive immune responses |
| Q38099414 | Regulators of chromatin state and transcription in CD4 T‐cell polarization |
| Q82644053 | Regulatory T cells fail to suppress CD4T+-bet+ T cells in relapsing multiple sclerosis patients |
| Q104736862 | Relationships between immune gene expression and circulating cytokine levels in wild house mice |
| Q97423592 | Requirements for the differentiation of innate T-bethigh memory-phenotype CD4+ T lymphocytes under steady state |
| Q35307873 | Retinal self-antigen induces a predominantly Th1 effector response in Axl and Mertk double-knockout mice |
| Q59645294 | Role of Environmental Epigenetics in Perinatal and Neonatal Development |
| Q38572497 | Role of Ets Proteins in Development, Differentiation, and Function of T-Cell Subsets |
| Q52956094 | Role of IL-12 Receptor β1 in Regulation of T Cell Response by APC in Experimental Autoimmune Encephalomyelitis |
| Q47659867 | SOCS1 gene expression is increased in severe pulmonary tuberculosis. |
| Q40634602 | STAT1 is essential for antimicrobial effector function but dispensable for gamma interferon production during Toxoplasma gondii infection. |
| Q41720069 | STAT1-Activating Cytokines Limit Th17 Responses through Both T-bet–Dependent and –Independent Mechanisms |
| Q47355847 | STAT4 and T-bet control follicular helper T cell development in viral infections. |
| Q34059593 | STAT4 deficiency fails to induce lung Th2 or Th17 immunity following primary or secondary respiratory syncytial virus (RSV) challenge but enhances the lung RSV-specific CD8+ T cell immune response to secondary challenge |
| Q28590165 | STAT4 serine phosphorylation is critical for IL-12-induced IFN-gamma production but not for cell proliferation |
| Q36431152 | STATs shape the active enhancer landscape of T cell populations |
| Q30433441 | Selectins in T-cell recruitment to non-lymphoid tissues and sites of inflammation |
| Q33756678 | Self-antigen prevents CD8 T cell effector differentiation by CD134 and CD137 dual costimulation |
| Q84667672 | Serine protease inhibitor, 4-(2-aminoethyl)-benzene sulfonyl fluoride, impairs IL-12-induced activation of pSTAT4β, NFκB, and select pro-inflammatory mediators from estrogen-treated mice |
| Q37400372 | Signal transducer and activator of transcription 4 is required for the transcription factor T-bet to promote T helper 1 cell-fate determination |
| Q57054689 | Signal transducer and activator of transcription 4 limits the development of adaptive regulatory T cells |
| Q35951819 | Signaling by IL-12 and IL-23 and the immunoregulatory roles of STAT4. |
| Q34208020 | Signaling pathways that lead to the silencing of the interleukin-4-producing potential in Th1 cells. |
| Q35207085 | Similarities and differences in CD4+ and CD8+ effector and memory T cell generation |
| Q47734878 | Small Nuclear Ribonucleoprotein Polypeptide A-Mediated Alternative Polyadenylation of STAT5B during Th1 Cell Differentiation |
| Q36399273 | Specific regulation of T helper cell 1-mediated murine colitis by CEACAM1. |
| Q34970100 | Stable T-bet(+)GATA-3(+) Th1/Th2 hybrid cells arise in vivo, can develop directly from naive precursors, and limit immunopathologic inflammation. |
| Q34995567 | Stat4 is critical for the balance between Th17 cells and regulatory T cells in colitis |
| Q36207257 | Stepwise regulation of TH1 responses in autoimmunity: IL-12-related cytokines and their receptors. |
| Q34762112 | Strategies for designing vaccines eliciting Th1 responses in humans |
| Q42002627 | T Helper Cell Differentiation, Heterogeneity, and Plasticity. |
| Q28081582 | T Helper Lymphocyte Subsets and Plasticity in Autoimmunity and Cancer: An Overview |
| Q35685186 | T cell directives for transcriptional regulation in asthma |
| Q42727084 | T cell responses: naive to memory and everything in between |
| Q92382973 | T follicular helper cell heterogeneity: Time, space, and function |
| Q46819043 | T helper 1-inducing property of IL-27/WSX-1 signaling is required for the induction of experimental colitis |
| Q35940715 | T helper 2 (Th2) cell differentiation, type 2 innate lymphoid cell (ILC2) development and regulation of interleukin-4 (IL-4) and IL-13 production |
| Q34612549 | T helper cell differentiation: on again, off again |
| Q41966167 | T helper cell polarisation in coeliac disease: any (T-)bet ? |
| Q34537828 | T helper subset development: roles of instruction, selection, and transcription |
| Q38238831 | T helper subsets in allergic eye disease |
| Q36228628 | T helper type 1-specific Brg1 recruitment and remodeling of nucleosomes positioned at the IFN-gamma promoter are Stat4 dependent |
| Q36765453 | T(H)-17 cells in the circle of immunity and autoimmunity |
| Q34797098 | T-Bet and Eomes Regulate the Balance between the Effector/Central Memory T Cells versus Memory Stem Like T Cells |
| Q33709760 | T-bet and eomesodermin play critical roles in directing T cell differentiation to Th1 versus Th17. |
| Q43006165 | T-bet and mucosal Th1 responses in the gastrointestinal tract |
| Q44586207 | T-bet as a possible therapeutic target in autoimmune disease |
| Q33756668 | T-bet down-modulation in tolerized Th1 effector CD4 cells confers a TCR-distal signaling defect that selectively impairs IFN-gamma expression |
| Q35212682 | T-bet expression in intratumoral lymphoid structures after neoadjuvant trastuzumab plus docetaxel for HER2-overexpressing breast carcinoma predicts survival |
| Q50078078 | T-bet expression in the iris and spleen parallels disease expression during endotoxin-induced uveitis |
| Q35895185 | T-bet expression is upregulated in active Behcet's disease |
| Q37891668 | T-bet in disease. |
| Q74082060 | T-bet is a STAT1-induced regulator of IL-12R expression in naïve CD4+ T cells |
| Q51981141 | T-bet is essential for the progression of experimental autoimmune encephalomyelitis |
| Q33952975 | T-bet is rapidly induced by interferon-γ in lymphoid and myeloid cells |
| Q36228767 | T-bet negatively regulates autoimmune myocarditis by suppressing local production of interleukin 17 |
| Q28588979 | T-bet regulates IgG class switching and pathogenic autoantibody production |
| Q36228437 | T-bet regulates Th1 responses through essential effects on GATA-3 function rather than on IFNG gene acetylation and transcription |
| Q35596780 | T-bet upregulation and subsequent interleukin 12 stimulation are essential for induction of Th1 mediated immunopathology in Crohn's disease. |
| Q41809838 | T-bet's ability to regulate individual target genes requires the conserved T-box domain to recruit histone methyltransferase activity and a separate family member-specific transactivation domain |
| Q28274670 | T-bet+ Treg Cells Undergo Abortive Th1 Cell Differentiation due to Impaired Expression of IL-12 Receptor β2 |
| Q38151473 | T-bet: a bridge between innate and adaptive immunity. |
| Q26772704 | TCR Signal Strength Alters T-DC Activation and Interaction Times and Directs the Outcome of Differentiation |
| Q39947013 | TGF-beta/Smad signaling defects in inflammatory bowel disease: mechanisms and possible novel therapies for chronic inflammation |
| Q82710916 | TOX regulates the differentiation of human natural killer cells from hematopoietic stem cells in vitro |
| Q40008934 | Tat-mediated intracellular delivery of T-bet protein into THP-1 cells can induce Th1-type response |
| Q38258564 | Tests for evaluating non-immediate allergic drug reactions. |
| Q42594137 | Th1 Cell Induction in Lymph Nodes According to a Red-Blue Chemokine Map |
| Q80373654 | Th1 and Th2 cytokine production is suppressed at the level of transcriptional regulation in Kawasaki disease |
| Q24800068 | Th1 and Th2 cytokines regulate proteoglycan-specific autoantibody isotypes and arthritis |
| Q39686503 | Th2 cell-specific cytokine expression and allergen-induced airway inflammation depend on JunB. |
| Q34312284 | The CD27 and CD70 Costimulatory Pathway Inhibits Effector Function of T Helper 17 Cells and Attenuates Associated Autoimmunity |
| Q46685523 | The CD4+CD26- T-cell population in classical Hodgkin's lymphoma displays a distinctive regulatory T-cell profile |
| Q35582560 | The IL-12 family of heterodimeric cytokines: new players in the regulation of T cell responses |
| Q47388000 | The IL-27R (WSX-1) is required to suppress T cell hyperactivity during infection |
| Q93158307 | The Immunobiology of the Interleukin-12 Family: Room for Discovery |
| Q41948431 | The Other T Helper Cells in Asthma Pathogenesis |
| Q37276576 | The PD-1/PD-L pathway is up-regulated during IL-12-induced suppression of EAE mediated by IFN-gamma |
| Q35607698 | The PDL1-PD1 Axis Converts Human T H 1 Cells into Regulatory T Cells |
| Q44928641 | The analysis of immunological profiles in wild animals: a case study on immunodynamics in the field vole, Microtus agrestis. |
| Q40689926 | The antiviral effects of acteoside and the underlying IFN-γ-inducing action |
| Q37038260 | The central memory CD4+ T cell population generated during Leishmania major infection requires IL-12 to produce IFN-gamma |
| Q80146459 | The contribution of transcription factor IRF1 to the interferon-gamma-interleukin 12 signaling axis and TH1 versus TH-17 differentiation of CD4+ T cells |
| Q35884264 | The development of effector and memory T cells in cutaneous leishmaniasis: the implications for vaccine development. |
| Q37376021 | The different faces of Notch in T-helper-cell differentiation |
| Q84923161 | The dynamic changes of T-bet(+)/GATA-3(+) and RORgammat(+)/FOXP3(+) cells in recipient spleens and grafts after rat orthotopic liver transplantation |
| Q27001581 | The effects of TLR activation on T-cell development and differentiation |
| Q92209373 | The evolving role of T-bet in resistance to infection |
| Q33861361 | The expressions of inflammatory factors and tissue inhibitor of matrix metalloproteinase-2 in human chronic periodontitis with type 2 diabetes mellitus. |
| Q35208763 | The function role of GATA-3 in Th1 and Th2 differentiation. |
| Q35143136 | The immunogenic peptide for Th1 development |
| Q38940423 | The immunosuppressive effects of Agyrolobium roseum and pinitol in experimental animals |
| Q36873811 | The infiltration, and prognostic importance, of Th1 lymphocytes vary in molecular subgroups of colorectal cancer |
| Q37103780 | The inflammatory Th 17 subset in immunity against self and non-self antigens |
| Q29614841 | The lineage decisions of helper T cells |
| Q37639934 | The multi-faceted influences of estrogen on lymphocytes: toward novel immuno-interventions strategies for autoimmunity management. |
| Q53011053 | The number of tumor infiltrating T-cell subsets in lymph nodes from patients with Hodgkin lymphoma is associated with the outcome after first line ABVD therapy |
| Q52923839 | The pro- and anti-inflammatory potential of IL-12: the dual role of Th1 cells |
| Q92463066 | The protective role of TBX21-1514T>C polymorphism in susceptibility to multiple sclerosis |
| Q35951809 | The role of IL-27 in the development of T-cell responses during parasitic infections |
| Q39388632 | The role of JAK-STAT signaling pathway and its regulators in the fate of T helper cells. |
| Q42514630 | The role of Sp1 and NF-kappa B in regulating CD40 gene expression |
| Q34664905 | The role of Th1/Th2 polarization in mucosal immunity |
| Q36165896 | The role of interferon-gamma on immune and allergic responses |
| Q38328527 | The role of upstream stimulatory factor 1 in the transcriptional regulation of the human TBX21 promoter mediated by the T-1514C polymorphism associated with systemic lupus erythematosus |
| Q35590727 | The split personality of NKT cells in malignancy, autoimmune and allergic disorders |
| Q41762357 | The transcription factor T-bet controls regulatory T cell homeostasis and function during type 1 inflammation |
| Q37029283 | The transcription factor T-bet is induced by multiple pathways and prevents an endogenous Th2 cell program during Th1 cell responses |
| Q36370178 | The transcription factor T-bet regulates mucosal T cell activation in experimental colitis and Crohn's disease |
| Q24321949 | The transcription factors T-bet and GATA-3 control alternative pathways of T-cell differentiation through a shared set of target genes |
| Q59812414 | Thy-1 (CD90) Signaling Preferentially Promotes RORγt Expression and a Th17 Response |
| Q36181770 | Tipifarnib-mediated suppression of T-bet-dependent signaling pathways |
| Q91945259 | Tissue-infiltrating immune cells as prognostic markers in oral squamous cell carcinoma: a systematic review and meta-analysis |
| Q37546067 | Tle4 regulates epigenetic silencing of gamma interferon expression during effector T helper cell tolerance. |
| Q34976886 | Tmevpg1, a candidate gene for the control of Theiler's virus persistence, could be implicated in the regulation of gamma interferon. |
| Q34249605 | Transcription factor T-bet regulates inflammatory arthritis through its function in dendritic cells |
| Q41825142 | Transcription factor T-bet represses expression of the inhibitory receptor PD-1 and sustains virus-specific CD8+ T cell responses during chronic infection. |
| Q34619808 | Transcription: tantalizing times for T cells |
| Q37875298 | Transcriptional Control of Natural Killer Cell Development and Function |
| Q40092481 | Transcriptional control of human T-BET expression: the role of Sp1. |
| Q36015482 | Transcriptional regulatory networks for CD4 T cell differentiation |
| Q34572232 | Transforming growth factor-beta in T-cell biology |
| Q37728121 | Treatment of allergic inflammation and hyperresponsiveness by a simple compound, Bavachinin, isolated from Chinese herbs |
| Q56895359 | Trichloroethylene-induced hypersensitivity dermatitis was associated with hepatic metabolic enzyme genes and immune-related genes |
| Q36710911 | Tumor infiltration by Tbet+ effector T cells and CD20+ B cells is associated with survival in gastric cancer patients |
| Q35593914 | Upregulation of T-bet expression in peripheral blood mononuclear cells during Vogt-Koyanagi-Harada disease |
| Q42269784 | Vaccination of Atlantic salmon, Salmo salar L., with Aeromonas salmonicida and infectious pancreatic necrosis virus (IPNV) showed a mixed Th1/Th2/Treg response |
| Q34519904 | Vaccine-induced protection against 3 systemic mycoses endemic to North America requires Th17 cells in mice. |
| Q37700167 | Virus-specific CD4 and CD8 T cell responses in the absence of Th1-associated transcription factors |
| Q35139941 | c-Abl-Mediated Tyrosine Phosphorylation of the T-bet DNA-Binding Domain Regulates CD4+ T-Cell Differentiation and Allergic Lung Inflammation |
| Q39738458 | c-Rel delivers a one-two punch in Th1 cell differentiation |
| Q37613173 | c‐Rel is an essential transcription factor for the development of acute graft‐versus‐host disease in mice |
| Q37062017 | ifn-γ-dependent secretion of IL-10 from Th1 cells and microglia/macrophages contributes to functional recovery after spinal cord injury |
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