| scholarly article | Q13442814 |
| P356 | DOI | 10.1038/NI807 |
| P698 | PubMed publication ID | 12055627 |
| P2093 | author name string | Lewis A Chodosh | |
| Steven L Reiner | |||
| Frances A High | |||
| Kara J Sykes | |||
| Alan C Mullen | |||
| Anne S Hutchins | |||
| Hubert W Lee | |||
| P2860 | cites work | DNA methylation patterns and epigenetic memory | Q22065780 |
| A novel transcription factor, T-bet, directs Th1 lineage commitment | Q22253874 | ||
| Tbx5 associates with Nkx2-5 and synergistically promotes cardiomyocyte differentiation | Q24291385 | ||
| Plasma cell differentiation requires the transcription factor XBP-1 | Q24291453 | ||
| Cell division regulates the T cell cytokine repertoire, revealing a mechanism underlying immune class regulation | Q24680549 | ||
| Compilation and analysis of sequences upstream from the translational start site in eukaryotic mRNAs | Q27860573 | ||
| A pituitary cell-restricted T box factor, Tpit, activates POMC transcription in cooperation with Pitx homeoproteins | Q28210920 | ||
| IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA | Q28214814 | ||
| Helper T cell differentiation is controlled by the cell cycle | Q28281505 | ||
| The T protein encoded by Brachyury is a tissue-specific transcription factor | Q28513249 | ||
| Hlx homeo box gene is essential for an inductive tissue interaction that drives expansion of embryonic liver and gut | Q28513958 | ||
| Tbx19, a tissue-selective regulator of POMC gene expression | Q28585325 | ||
| A murine model of Holt-Oram syndrome defines roles of the T-box transcription factor Tbx5 in cardiogenesis and disease | Q28594121 | ||
| Notch1 regulates maturation of CD4+ and CD8+ thymocytes by modulating TCR signal strength | Q28594158 | ||
| Notch-RBP-J signaling is involved in cell fate determination of marginal zone B cells | Q28594415 | ||
| Production of high-titer helper-free retroviruses by transient transfection | Q29547802 | ||
| High density synthetic oligonucleotide arrays | Q29616560 | ||
| Opening of compacted chromatin by early developmental transcription factors HNF3 (FoxA) and GATA-4 | Q29618736 | ||
| IL-18-stimulated GADD45 beta required in cytokine-induced, but not TCR-induced, IFN-gamma production. | Q31929678 | ||
| T-bet is rapidly induced by interferon-gamma in lymphoid and myeloid cells | Q33952975 | ||
| T-targets: clues to understanding the functions of T-box proteins | Q34124665 | ||
| Helper T cell differentiation, inside and out. | Q34282360 | ||
| Novel murine homeo box gene on chromosome 1 expressed in specific hematopoietic lineages and during embryogenesis | Q34530752 | ||
| GATA-3 induces T helper cell type 2 (Th2) cytokine expression and chromatin remodeling in committed Th1 cells | Q35834668 | ||
| Heterogeneity of helper/inducer T lymphocytes. I. Lymphokine production and lymphokine responsiveness | Q36354289 | ||
| Distinct methylation of the interferon gamma (IFN-gamma) and interleukin 3 (IL-3) genes in newly activated primary CD8+ T lymphocytes: regional IFN-gamma promoter demethylation and mRNA expression are heritable in CD44(high)CD8+ T cells | Q36851717 | ||
| A nuclease-hypersensitive region forms de novo after chromosome replication | Q36923158 | ||
| Distinct effects of T-bet in TH1 lineage commitment and IFN-gamma production in CD4 and CD8 T cells | Q40757721 | ||
| Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice | Q41185362 | ||
| Ectopic expression of activated Stat6 induces the expression of Th2-specific cytokines and transcription factors in developing Th1 cells | Q41712990 | ||
| Instruction for cytokine expression in T helper lymphocytes in relation to proliferation and cell cycle progression | Q42267729 | ||
| Early transcription and silencing of cytokine genes underlie polarization of T helper cell subsets. | Q46001789 | ||
| Cell cycle controlling the silencing and functioning of mammalian activators. | Q51061285 | ||
| Pax5/BSAP maintains the identity of B cells in late B lymphopoiesis. | Q51065317 | ||
| Role of T-bet in commitment of TH1 cells before IL-12-dependent selection. | Q51065721 | ||
| DNA replication in vitro erases a Xenopus 5S RNA gene transcription complex. | Q52136956 | ||
| Interleukin-12 regulates the proliferation of Th1, but not Th2 or Th0, clones. | Q54560001 | ||
| Regulation of B lymphocyte and macrophage development by graded expression of PU.1. | Q55033922 | ||
| Inhibition of Th1 Development Mediated by GATA-3 through an IL-4-Independent Mechanism | Q61357092 | ||
| Cell-type-restricted binding of the transcription factor NFAT to a distal IL-4 enhancer in vivo | Q73998192 | ||
| Modulation of chromatin structure regulates cytokine gene expression during T cell differentiation | Q77769108 | ||
| P433 | issue | 7 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 652-658 | |
| P577 | publication date | 2002-06-10 | |
| P1433 | published in | Nature Immunology | Q1071725 |
| P1476 | title | Hlx is induced by and genetically interacts with T-bet to promote heritable T(H)1 gene induction | |
| P478 | volume | 3 |
| Q38106128 | 'All things considered': transcriptional regulation of T helper type 2 cell differentiation from precursor to effector activation |
| Q58799723 | A metabolic interplay coordinated by HLX regulates myeloid differentiation and AML through partly overlapping pathways |
| Q36497388 | ATF3 regulates MCMV infection in mice by modulating IFN-gamma expression in natural killer cells |
| Q41052256 | An atlas of mouse CD4(+) T cell transcriptomes |
| Q35164202 | An epigenetic view of helper T cell differentiation |
| Q31089432 | Analysis of the transcriptomes downstream of Eyeless and the Hedgehog, Decapentaplegic and Notch signaling pathways in Drosophila melanogaster |
| Q42739331 | Anomalous type 17 response to viral infection by CD8+ T cells lacking T-bet and eomesodermin. |
| Q42287218 | Asymmetric proteasome segregation as a mechanism for unequal partitioning of the transcription factor T-bet during T lymphocyte division |
| Q37418406 | Biochemical signaling pathways for memory T cell recall |
| Q33682719 | C/EBPepsilon directs granulocytic-vs-monocytic lineage determination and confers chemotactic function via Hlx. |
| Q50054341 | CD38-NAD+Axis Regulates Immunotherapeutic Anti-Tumor T Cell Response |
| Q34813153 | CD4 T cells: fates, functions, and faults |
| Q36831813 | CD44 Reciprocally regulates the differentiation of encephalitogenic Th1/Th17 and Th2/regulatory T cells through epigenetic modulation involving DNA methylation of cytokine gene promoters, thereby controlling the development of experimental autoimmun |
| Q37999790 | CD4⁺T cells: differentiation and functions |
| Q36544053 | Cell biology of T cell activation and differentiation |
| Q50955426 | Cell division curtails helper phenotype plasticity and expedites helper T-cell differentiation. |
| Q36794284 | Cell lineage regulators in B and T cell development |
| Q42929533 | Chromatin remodeling by the SWI/SNF-like BAF complex and STAT4 activation synergistically induce IL-12Rbeta2 expression during human Th1 cell differentiation |
| Q57271625 | Coffee Consumption and Whole-Blood Gene Expression in the Norwegian Women and Cancer Post-Genome Cohort |
| Q34240220 | Complex interactions of transcription factors in mediating cytokine biology in T cells |
| Q36282244 | Comprehensive epigenetic profiling identifies multiple distal regulatory elements directing transcription of the gene encoding interferon-gamma |
| Q28589387 | Control of Effector CD8 + T Cell Function by the Transcription Factor Eomesodermin |
| Q37163479 | Control of IL-4 expression in T helper 1 and 2 cells. |
| Q37283066 | Cutting edge: Ikaros is a regulator of Th2 cell differentiation |
| Q35150010 | Cytokines and transcription factors that regulate T helper cell differentiation: new players and new insights. |
| Q38851770 | DNA Methylation: a New Player in Multiple Sclerosis |
| Q36080339 | De novo DNA methylation is required to restrict T helper lineage plasticity |
| Q35769454 | Development and function of T helper 1 cells |
| Q35089039 | Development of a unique epigenetic signature during in vivo Th17 differentiation |
| Q47161655 | Differential Expression of Serum MicroRNAs Supports CD4⁺ T Cell Differentiation into Th2/Th17 Cells in Severe Equine Asthma. |
| Q38621051 | Differential Expression of miRNA Regulates T Cell Differentiation and Plasticity During Visceral Leishmaniasis Infection |
| Q29614838 | Differentiation of effector CD4 T cell populations (*) |
| Q36181281 | Diversity of human and mouse homeobox gene expression in development and adult tissues |
| Q35081245 | Dual function of polycomb group proteins in differentiated murine T helper (CD4+) cells |
| Q34465675 | Effector and memory CD8+ T cell fate coupled by T-bet and eomesodermin |
| Q30636150 | Epigenetic Activation and Silencing of the Gene that Encodes IFN-γ. |
| Q40464790 | Epigenetic changes in the repression and induction of asparagine synthetase in human leukemic cell lines. |
| Q37371624 | Epigenetic control of T-helper-cell differentiation |
| Q38107626 | Epigenetic control of cytokine gene expression: regulation of the TNF/LT locus and T helper cell differentiation |
| Q35084270 | Epigenetic mechanisms that regulate antigen receptor gene expression |
| Q37386440 | Epigenetic targets for reversing immune defects caused by alcohol exposure |
| Q36403225 | Ets-1, a functional cofactor of T-bet, is essential for Th1 inflammatory responses |
| Q35067776 | Feed-forward transcriptional programming by nuclear receptors: regulatory principles and therapeutic implications |
| Q45902839 | Fetal Epigenetic Mechanisms and Innate Immunity in Asthma |
| Q58478744 | GATA-3 Promotes Maturation, IFN-γ Production, and Liver-Specific Homing of NK Cells |
| Q73153297 | GATA-3 suppresses Th1 development by downregulation of Stat4 and not through effects on IL-12Rbeta2 chain or T-bet |
| Q52005548 | Genetic Reprogramming of Primary Human T Cells Reveals Functional Plasticity in Th Cell Differentiation |
| Q37498951 | Genetic and epigenetic networks controlling T helper 1 cell differentiation. |
| Q37620249 | Gαq Regulates the Development of Rheumatoid Arthritis by Modulating Th1 Differentiation. |
| Q92342000 | Helper T cell differentiation |
| Q35176407 | Helper T cell differentiation and the problem of cellular inheritance |
| Q36623362 | Helper T-cell identity and evolution of differential transcriptomes and epigenomes. |
| Q28077926 | Histone Posttranslational Modifications of CD4⁺ T Cell in Autoimmune Diseases |
| Q24683785 | Hlx homeobox transcription factor negatively regulates interferon-gamma production in monokine-activated natural killer cells |
| Q37502276 | How diverse--CD4 effector T cells and their functions |
| Q50959583 | Human T helper (Th) cell lineage commitment is not directly linked to the secretion of IFN-gamma or IL-4: characterization of Th cells isolated by FACS based on IFN-gamma and IL-4 secretion. |
| Q40098428 | Hypermethylation of MIR21 in CD4+ T cells from patients with relapsing-remitting multiple sclerosis associates with lower miRNA-21 levels and concomitant up-regulation of its target genes |
| Q36403717 | IL-2 production in developing Th1 cells is regulated by heterodimerization of RelA and T-bet and requires T-bet serine residue 508. |
| Q40044539 | IL-4 enhances IL-10 production in Th1 cells: implications for Th1 and Th2 regulation. |
| Q33593953 | Ikaros silences T-bet expression and interferon-gamma production during T helper 2 differentiation |
| Q37194984 | In vitro and in vivo differentiated effector CD8 T cells display divergent histone acetylation patterns within the Ifng locus |
| Q51977261 | Induction of a Th1 response from Th2-polarized T cells by activated dendritic cells: dependence on TCR:peptide-MHC interaction, ICAM-1, IL-12, and IFN-gamma. |
| Q34976848 | Infection-Triggered Regulatory Mechanisms Override the Role of STAT 4 in Control of the Immune Response to Influenza Virus Antigens |
| Q27489517 | Inhibition of Intrahepatic Gamma Interferon Production by Hepatitis C Virus Nonstructural Protein 5A in Transgenic Mice |
| Q79366613 | Involvement of GATA3 in protein kinase C theta-induced Th2 cytokine expression |
| Q41643177 | Janus-kinase-3-dependent signals induce chromatin remodeling at the Ifng locus during T helper 1 cell differentiation |
| Q64260848 | Loss of Jak2 protects cardiac allografts from chronic rejection by attenuating Th1 response along with increased regulatory T cells |
| Q37849185 | Maternal signals for progeny prevention against allergy and asthma |
| Q27687830 | Mechanisms underlying helper T-cell plasticity: implications for immune-mediated disease |
| Q36385668 | Methylomic markers of persistent childhood asthma: a longitudinal study of asthma-discordant monozygotic twins |
| Q56988839 | NK cells gain higher IFN-γ competence during terminal differentiation |
| Q33246618 | New approach to in situ quantification of ovarian gene expression in rat using a laser microdissection technique: relationship between follicle types and regulation of inhibin-alpha and cytochrome P450aromatase genes in the rat ovary |
| Q35762439 | Novel ChIP-based strategies to uncover transcription factor target genes in the immune system |
| Q50989710 | Nuclear repositioning marks the selective exclusion of lineage-inappropriate transcription factor loci during T helper cell differentiation. |
| Q38291705 | Onecut transcription factor OC2 is a direct target of T-bet in type-1 T-helper cells |
| Q28771486 | Opposing roles of STAT4 and Dnmt3a in Th1 gene regulation |
| Q34285649 | Peripheral CD4+ T-cell differentiation regulated by networks of cytokines and transcription factors. |
| Q42238387 | Phenotypic and transcriptional profile correlates with functional plasticity of antigen-specific CD4+ T cells. |
| Q28256001 | Regulation of interferon-gamma during innate and adaptive immune responses |
| Q37802427 | Regulation of the Ifng locus in the context of T-lineage specification and plasticity. |
| Q38099414 | Regulators of chromatin state and transcription in CD4 T-cell polarization |
| Q38147883 | Regulatory mechanisms that control T-follicular helper and T-helper 1 cell flexibility |
| Q36173322 | Relationship between susceptibility of Blackface sheep to Teladorsagia circumcincta infection and an inflammatory mucosal T cell response |
| Q36028191 | Roles of interferon-regulatory factors in T-helper-cell differentiation |
| Q33756678 | Self-antigen prevents CD8 T cell effector differentiation by CD134 and CD137 dual costimulation |
| Q37400372 | Signal transducer and activator of transcription 4 is required for the transcription factor T-bet to promote T helper 1 cell-fate determination |
| Q34208020 | Signaling pathways that lead to the silencing of the interleukin-4-producing potential in Th1 cells. |
| Q81180288 | Sliding doors in the immune response |
| Q34970100 | Stable T-bet(+)GATA-3(+) Th1/Th2 hybrid cells arise in vivo, can develop directly from naive precursors, and limit immunopathologic inflammation. |
| Q42130325 | Stat4 limits DNA methyltransferase recruitment and DNA methylation of the IL-18Ralpha gene during Th1 differentiation |
| Q34916338 | Stochastic cytokine expression induces mixed T helper cell States |
| Q80726846 | Superantigen-induced CD4+ T cell tolerance is associated with DNA methylation and histone hypo-acetylation at cytokine gene loci |
| Q35685186 | T cell directives for transcriptional regulation in asthma |
| Q58606230 | T cell epigenetic remodeling and accelerated epigenetic aging are linked to long-term immune alterations in childhood cancer survivors |
| Q28506783 | T helper 17 lineage differentiation is programmed by orphan nuclear receptors ROR alpha and ROR gamma |
| Q36228628 | T helper type 1-specific Brg1 recruitment and remodeling of nucleosomes positioned at the IFN-gamma promoter are Stat4 dependent |
| Q43006165 | T-bet and mucosal Th1 responses in the gastrointestinal tract |
| Q24556669 | T-bet antagonizes mSin3a recruitment and transactivates a fully methylated IFN-gamma promoter via a conserved T-box half-site |
| Q35848548 | T-bet concomitantly controls migration, survival, and effector functions during the development of Valpha14i NKT cells |
| Q37478410 | T-bet dependent removal of Sin3A-histone deacetylase complexes at the Ifng locus drives Th1 differentiation |
| Q33756668 | T-bet down-modulation in tolerized Th1 effector CD4 cells confers a TCR-distal signaling defect that selectively impairs IFN-gamma expression |
| Q42742129 | T-bet is a critical determinant in the instability of the IL-17-secreting T-helper phenotype. |
| Q36228437 | T-bet regulates Th1 responses through essential effects on GATA-3 function rather than on IFNG gene acetylation and transcription |
| Q41809838 | T-bet's ability to regulate individual target genes requires the conserved T-box domain to recruit histone methyltransferase activity and a separate family member-specific transactivation domain |
| Q35848328 | T-bet, a Th1 transcription factor, is up-regulated in T cells from patients with aplastic anemia |
| Q38151473 | T-bet: a bridge between innate and adaptive immunity. |
| Q42782373 | T-box gene eomesodermin and the homeobox-containing Mix/Bix gene mtx2 regulate epiboly movements in the zebrafish |
| Q28732344 | TBX21 and HLX1 polymorphisms influence cytokine secretion at birth |
| Q24558608 | TBX21: a functional variant predicts improvement in asthma with the use of inhaled corticosteroids |
| Q34275513 | The Coherent Feedforward Loop Serves as a Sign-sensitive Delay Element in Transcription Networks |
| Q34988184 | The VEGF-regulated transcription factor HLX controls the expression of guidance cues and negatively regulates sprouting of endothelial cells |
| Q37038260 | The central memory CD4+ T cell population generated during Leishmania major infection requires IL-12 to produce IFN-gamma |
| Q80146459 | The contribution of transcription factor IRF1 to the interferon-gamma-interleukin 12 signaling axis and TH1 versus TH-17 differentiation of CD4+ T cells |
| Q27001581 | The effects of TLR activation on T-cell development and differentiation |
| Q29614841 | The lineage decisions of helper T cells |
| Q43199035 | The mTOR kinase determines effector versus memory CD8+ T cell fate by regulating the expression of transcription factors T-bet and Eomesodermin |
| Q88721030 | The transcription factor Bhlhe40 is a switch of inflammatory versus antiinflammatory Th1 cell fate determination |
| Q28590652 | The transcription factor GATA3 actively represses RUNX3 protein-regulated production of interferon-gamma |
| Q35105032 | The transcription factor PU.1 is required for the development of IL-9-producing T cells and allergic inflammation. |
| Q34249605 | Transcription factor T-bet regulates inflammatory arthritis through its function in dendritic cells |
| Q38123463 | Transcription factor interplay in T helper cell differentiation |
| Q37059174 | Transcription factor-dependent chromatin remodeling of Il18r1 during Th1 and Th2 differentiation |
| Q79462842 | Transcription factors T-bet and Runx3 cooperate to activate Ifng and silence Il4 in T helper type 1 cells |
| Q34631682 | Transcriptional and epigenetic regulation of T-helper lineage specification |
| Q35090249 | Transcriptional control of rapid recall by memory CD4 T cells |
| Q38820302 | Transcriptional regulation of mast cell and basophil lineage commitment. |
| Q36015482 | Transcriptional regulatory networks for CD4 T cell differentiation |
| Q37191628 | Transmethylation in immunity and autoimmunity |
| Q28207959 | Tumor suppression by Ink4a-Arf: progress and puzzles |
| Q24337273 | Txk, a member of the non-receptor tyrosine kinase of the Tec family, forms a complex with poly(ADP-ribose) polymerase 1 and elongation factor 1alpha and regulates interferon-gamma gene transcription in Th1 cells |
| Q39738458 | c-Rel delivers a one-two punch in Th1 cell differentiation |
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