TCR-mediated Notch signaling regulates proliferation and IFN-gamma production in peripheral T cells

scientific article published in September 2003

TCR-mediated Notch signaling regulates proliferation and IFN-gamma production in peripheral T cells is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.4049/JIMMUNOL.171.6.3019
P698PubMed publication ID12960327
P5875ResearchGate publication ID10579241

P2093author name stringLucio Miele
Todd E Golde
Tanapat Palaga
Barbara A Osborne
P433issue6
P407language of work or nameEnglishQ1860
P304page(s)3019-3024
P577publication date2003-09-01
P1433published inJournal of ImmunologyQ3521441
P1476titleTCR-mediated Notch signaling regulates proliferation and IFN-gamma production in peripheral T cells
P478volume171

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cites work (P2860)
Q55114872A Review of Notch Processing With New Insights Into Ligand-Independent Notch Signaling in T-Cells.
Q84115725A role for the atopy-associated gene PHF11 in T-cell activation and viability
Q33385380Aberrant expression of Notch signaling molecules in patients with immune thrombocytopenic purpura
Q64241193Adenosine A2A Receptor Stimulation Inhibits TCR-Induced Notch1 Activation in CD8+T-Cells
Q35666699Alternative routes to maturity: branch points and pathways for generating follicular and marginal zone B cells
Q37360497Amyloid precursor family proteins are expressed by thymic and lymph node stromal cells but are not required for lymphocyte development
Q35401923Blockade of Notch ligand δ1 promotes allograft survival by inhibiting alloreactive Th1 cells and cytotoxic T cell generation
Q95840974CD28 Signaling Drives Notch Ligand Expression on CD4 T Cells
Q58781616Cancer Cells Exploit Notch Signaling to Redefine a Supportive Cytokine Milieu
Q48278683Cancer stem cells as targets for immunotherapy
Q64907961Cymerus™ iPSC-MSCs significantly prolong survival in a pre-clinical, humanized mouse model of Graft-vs-host disease.
Q36328975Delta-Like-1 Changes the Immunomodulatory Property of OP9 Cells
Q64085682Determinant roles of dendritic cell-expressed Notch Delta-like and Jagged ligands on anti-tumor T cell immunity
Q29614838Differentiation of effector CD4 T cell populations (*)
Q37728915Direct regulation of interleukin-6 expression by Notch signaling in macrophages
Q33417841Disruption of hSWI/SNF complexes in T cells by WAS mutations distinguishes X-linked thrombocytopenia from Wiskott-Aldrich syndrome
Q24813057E3 ubiquitin ligases and their control of T cell autoreactivity
Q27026592Early signaling events that underlie fate decisions of naive CD4(+) T cells toward distinct T-helper cell subsets
Q35050406Emerging molecular targets for the treatment of pre-eclampsia
Q54392651Engagement of activated Notch signalling in collagen II-specific T helper type 1 (Th1)- and Th17-type expansion involving Notch3 and Delta-like1.
Q36639992Essential role of Notch signaling in effector memory CD8+ T cell-mediated airway hyperresponsiveness and inflammation.
Q89722136GCNT1-Mediated O-Glycosylation of the Sialomucin CD43 Is a Sensitive Indicator of Notch Signaling in Activated T Cells
Q46113876Gamma-secretase inhibitor reduces allergic pulmonary inflammation by modulating Th1 and Th2 responses.
Q46943642Gamma-secretase inhibitors exerts antitumor activity via down-regulation of Notch and Nuclear factor kappa B in human tongue carcinoma cells
Q26745893Hacker within! Ehrlichia chaffeensis Effector Driven Phagocyte Reprogramming Strategy
Q40717051Helicobacter pylori Infection of Gastric Epithelial Cells Affects NOTCH Pathway In Vitro
Q36306608Hypertonic saline attenuates expression of Notch signaling and proinflammatory mediators in activated microglia in experimentally induced cerebral ischemia and hypoxic BV-2 microglia
Q24313193IFN-lambda1 (IL-29) inhibits GATA3 expression and suppresses Th2 responses in human naive and memory T cells
Q36779384IL-21-stimulated human plasmacytoid dendritic cells secrete granzyme B, which impairs their capacity to induce T-cell proliferation
Q33921337Identification of novel targets of CSL-dependent Notch signaling in hematopoiesis
Q90640291Immunotherapy: Newer Therapeutic Armamentarium against Cancer Stem Cells
Q33419208Inactivation of Notch signaling reverses the Th17/Treg imbalance in cells from patients with immune thrombocytopenia
Q34364561Inhibition of γ-secretase cleavage in the notch signaling pathway blocks HSV-2-induced type I and type II interferon production
Q47619638Instruction of distinct CD4 T helper cell fates by different notch ligands on antigen-presenting cells
Q35321543Involvement of Notch signaling in hippocampal synaptic plasticity
Q35980526Involvement of Notch signaling pathway in regulating IL-12 expression via c-Rel in activated macrophages
Q33305435Involvement of notch signaling in wound healing
Q47762950Jagged1 regulates the activation of astrocytes via modulation of NFkappaB and JAK/STAT/SOCS pathways
Q35918324Mind bomb-1 in dendritic cells is specifically required for Notch-mediated T helper type 2 differentiation
Q41974098NOTCH signaling in immune-mediated bone marrow failure of aplastic anemia
Q39938670NOTCH1 Can Initiate NF-κB Activation via Cytosolic Interactions with Components of the T Cell Signalosome
Q24317458NUMBL interacts with TAB2 and inhibits TNFalpha and IL-1beta-induced NF-kappaB activation
Q37578833Non-Canonical Notch Signaling Drives Activation and Differentiation of Peripheral CD4(+) T Cells.
Q38299924Non-canonical notch signaling in cancer and immunity
Q36448329Notch 1 activation in the molecular pathogenesis of T-cell acute lymphoblastic leukaemia
Q40566978Notch 1 signaling regulates peripheral T cell activation
Q64885841Notch Signaling Regulates Immune Responses in Atherosclerosis.
Q55422791Notch Signaling and Immune Regulation in Alloimmunity.
Q39274325Notch Signaling in T Helper Cell Subsets: Instructor or Unbiased Amplifier?
Q36944897Notch and NFkappaB signaling pathways: Do they collaborate in normal vertebrate brain development and function?
Q37952793Notch and inflammatory T-cell response: new developments and challenges
Q33356044Notch and presenilin regulate cellular expansion and cytokine secretion but cannot instruct Th1/Th2 fate acquisition
Q79361598Notch and the immune system
Q28594834Notch directly regulates Gata3 expression during T helper 2 cell differentiation
Q47308030Notch ligand Delta-like1 enhances degranulation and cytokine production through a novel Notch/Dok-1/MAPKs pathway in vitro
Q52043238Notch ligands Delta-like1, Delta-like4 and Jagged1 differentially regulate activation of peripheral T helper cells.
Q35219642Notch regulates cytolytic effector function in CD8+ T cells.
Q35676281Notch regulation of lymphocyte development and function.
Q24656638Notch signaling in CD4 and CD8 T cell development
Q37002843Notch signaling in differentiation and function of dendritic cells
Q37594765Notch signaling in the hematopoietic system
Q42522636Notch signaling is activated by TLR stimulation and regulates macrophage functions
Q36403646Notch signaling is an important regulator of type 2 immunity.
Q37109326Notch signaling mediates G1/S cell-cycle progression in T cells via cyclin D3 and its dependent kinases
Q39258612Notch signaling regulates PD-1 expression during CD8(+) T-cell activation
Q37729629Notch signaling regulates expression of Mcl-1 and apoptosis in PPD-treated macrophages
Q35091395Notch signaling regulates mouse and human Th17 differentiation
Q81939673Notch signaling regulates the FOXP3 promoter through RBP-J- and Hes1-dependent mechanisms
Q87842237Notch signaling represents an important checkpoint between follicular T-helper and canonical T-helper 2 cell fate
Q37600797Notch signaling: key role in intrauterine infection/inflammation, embryonic development, and white matter damage?
Q36684906Notch signalling during peripheral T-cell activation and differentiation
Q50594755Notch signalling regulates cytokine production by CD8+ and CD4+ T cells.
Q40470939Notch1 antiapoptotic activity is abrogated by caspase cleavage in dying T lymphocytes.
Q24297567Notch1 augments NF-kappaB activity by facilitating its nuclear retention
Q52562489Notch1 co-localizes with CD4 on activated T cells and Notch signaling is required for IL-10 production.
Q45345853Notch2 integrates signaling by the transcription factors RBP-J and CREB1 to promote T cell cytotoxicity.
Q47232433Novel TCR-Mediated Mechanisms of Notch Activation and Signaling.
Q80146628Off the beaten pathway: the complex cross talk between Notch and NF-kappaB
Q42409435Osteoclast-Primed Foxp3+ CD8 T Cells Induce T-bet, Eomesodermin, and IFN-γ To Regulate Bone Resorption.
Q90706153PD-L1 expression levels on tumor cells affect their immunosuppressive activity
Q42321322PKCθ links proximal T cell and Notch signaling through localized regulation of the actin cytoskeleton
Q42833516Pancreatic regeneration in chronic pancreatitis requires activation of the notch signaling pathway
Q48113221Perspectives on the discovery of NOTCH2-specific inhibitors
Q35007792Phase 2 study of RO4929097, a gamma-secretase inhibitor, in metastatic melanoma: SWOG 0933.
Q33760888Photosensitivity diseases: cutaneous lupus erythematosus
Q28587555Presenilins regulate alphabeta T cell development by modulating TCR signaling
Q47292277RBPJ mediates uterine repair in the mouse and is reduced in women with recurrent pregnancy loss.
Q49222919Regulation of CD8+ T Cells and Antitumor Immunity by Notch Signaling
Q47607371Regulation of alphabeta/gammadelta T cell lineage commitment and peripheral T cell responses by Notch/RBP-J signaling
Q37700831Regulation of dendritic cell differentiation and function by Notch and Wnt pathways
Q38105858Regulation of innate and adaptive immunity by Notch
Q28256001Regulation of interferon-gamma during innate and adaptive immune responses
Q36794296Regulation of lymphocyte development by Notch signaling
Q34017104Rescue of notch-1 signaling in antigen-specific CD8+ T cells overcomes tumor-induced T-cell suppression and enhances immunotherapy in cancer
Q55315202Rotenone Treatment Reveals a Role for Electron Transport Complex I in the Subcellular Localization of Key Transcriptional Regulators During T Helper Cell Differentiation.
Q39402895Spectrum of T-lymphocyte activities regulating allergic lung inflammation
Q41962999Suppression of Th2 cell development by Notch ligands Delta1 and Delta4
Q35131705T cells develop normally in the absence of both Deltex1 and Deltex2
Q91620717Targeting signalling pathways and the immune microenvironment of cancer stem cells - a clinical update
Q64905994The Notch ligand DNER regulates macrophage IFNγ release in chronic obstructive pulmonary disease.
Q39015607The deposition of Notch1 in hepatitis B virus-associated nephropathy and its role in hepatitis B virus X protein-induced epithelial-mesenchymal transdifferentiation and immunity disorder in renal tubular epithelial cells
Q37376021The different faces of Notch in T-helper-cell differentiation
Q27002959The immunological synapse: the gateway to the HIV reservoir
Q50726643The interleukin-4 enhancer CNS-2 is regulated by Notch signals and controls initial expression in NKT cells and memory-type CD4 T cells.
Q37412934The transcription factor E74-like factor 4 suppresses differentiation of proliferating CD4+ T cells to the Th17 lineage
Q36973664Therapeutic targeting of NOTCH signaling ameliorates immune-mediated bone marrow failure of aplastic anemia
Q37773429Transcription factor regulation of CD8+ T-cell memory and exhaustion
Q42428739Transcriptional Profiling of Th2 Cells Identifies Pathogenic Features Associated with Asthma
Q51945372Transcriptional regulation of GATA3 in T helper cells by the integrated activities of transcription factors downstream of the interleukin-4 receptor and T cell receptor.
Q42001733Treg-mediated immunosuppression involves activation of the Notch-HES1 axis by membrane-bound TGF-beta
Q40584271p53 regulates thymic Notch1 activation