| scholarly article | Q13442814 |
| review article | Q7318358 |
| P2093 | author name string | Susan Winandy | |
| Martin Peter Steinbuck | |||
| P2860 | cites work | TrkA receptor activation by nerve growth factor induces shedding of the p75 neurotrophin receptor followed by endosomal gamma-secretase-mediated release of the p75 intracellular domain | Q48314000 |
| Evidence for a role for notch signaling in the cytokine-dependent survival of activated T cells | Q79174343 | ||
| Stage-specific and differential notch dependency at the alphabeta and gammadelta T lineage bifurcation | Q79825014 | ||
| Expression of Notch receptors and ligands on immature and mature T cells | Q83396424 | ||
| Inhibitors of gamma-secretase block in vivo and in vitro T helper type 1 polarization by preventing Notch upregulation of Tbx21 | Q95814547 | ||
| The interleukin-4 enhancer CNS-2 is regulated by Notch signals and controls initial expression in NKT cells and memory-type CD4 T cells | Q50726643 | ||
| Notch1 expression in early lymphopoiesis influences B versus T lineage determination | Q51085324 | ||
| Presenilin/gamma-secretase activity regulates protein clearance from the endocytic recycling compartment. | Q51808109 | ||
| Notch ligands Delta-like1, Delta-like4 and Jagged1 differentially regulate activation of peripheral T helper cells. | Q52043238 | ||
| Drosophila deltex mediates suppressor of Hairless-independent and late-endosomal activation of Notch signaling. | Q52086514 | ||
| Requirement for dynamin during Notch signaling in Drosophila neurogenesis. | Q52191286 | ||
| Specific truncations of Drosophila Notch define dominant activated and dominant negative forms of the receptor. | Q52223825 | ||
| Requirements for presenilin-dependent cleavage of notch and other transmembrane proteins. | Q52583319 | ||
| Roles of Drosophila deltex in Notch receptor endocytic trafficking and activation. | Q52715119 | ||
| Antiparallel segregation of notch components in the immunological synapse directs reciprocal signaling in allogeneic Th:DC conjugates. | Q53542217 | ||
| Structural and functional properties of the human notch-1 ligand binding region. | Q53630243 | ||
| A ligand-induced extracellular cleavage regulates gamma-secretase-like proteolytic activation of Notch1 | Q73958442 | ||
| Endogenous presenilin-1 targets to endocytic rather than biosynthetic compartments | Q74104478 | ||
| Expression of Notch ligands, Jagged1, 2 and Delta1 in antigen presenting cells in mice | Q77632288 | ||
| AIP4/Itch regulates Notch receptor degradation in the absence of ligand | Q21144278 | ||
| Expression pattern of notch1, 2 and 3 and Jagged1 and 2 in lymphoid and stromal thymus components: distinct ligand-receptor interactions in intrathymic T cell development | Q22010181 | ||
| Human deltex is a conserved regulator of Notch signalling | Q24317290 | ||
| TAN-1, the human homolog of the Drosophila Notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms | Q24320364 | ||
| Notch signaling in CD4 and CD8 T cell development | Q24656638 | ||
| Identification of a conserved negative regulatory sequence that influences the leukemogenic activity of NOTCH1 | Q24670708 | ||
| The Notch1 receptor is cleaved constitutively by a furin-like convertase | Q24671866 | ||
| Structural basis for autoinhibition of Notch | Q27644319 | ||
| Structure of the Notch1-negative regulatory region: implications for normal activation and pathogenic signaling in T-ALL | Q27653136 | ||
| A novel proteolytic cleavage involved in Notch signaling: the role of the disintegrin-metalloprotease TACE | Q28139998 | ||
| A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain | Q28141707 | ||
| Protein kinase C-dependent alpha-secretase competes with beta-secretase for cleavage of amyloid-beta precursor protein in the trans-golgi network | Q28143129 | ||
| Regulated intramembrane proteolysis: a control mechanism conserved from bacteria to humans | Q28145545 | ||
| The dynamin superfamily: universal membrane tubulation and fission molecules? | Q28252404 | ||
| The epsin protein family: coordinators of endocytosis and signaling | Q28274114 | ||
| Presenilin-1, Nicastrin, Amyloid Precursor Protein, and γ-Secretase Activity Are Co-localized in the Lysosomal Membrane | Q28568133 | ||
| Notch-RBP-J signaling is involved in cell fate determination of marginal zone B cells | Q28594415 | ||
| Notch directly regulates Gata3 expression during T helper 2 cell differentiation | Q28594834 | ||
| Calcium depletion dissociates and activates heterodimeric notch receptors | Q28609673 | ||
| Kuzbanian controls proteolytic processing of Notch and mediates lateral inhibition during Drosophila and vertebrate neurogenesis | Q28646378 | ||
| Mechanisms of endocytosis | Q29547609 | ||
| The canonical Notch signaling pathway: unfolding the activation mechanism | Q29547725 | ||
| Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia | Q29614269 | ||
| Endocytosis and signalling: intertwining molecular networks | Q29616848 | ||
| Amyloid precursor protein trafficking, processing, and function | Q29617429 | ||
| The nuts and bolts of AGC protein kinases | Q29617465 | ||
| Molecular architecture of the multisubunit homotypic fusion and vacuole protein sorting (HOPS) tethering complex | Q30505172 | ||
| Notch and presenilin regulate cellular expansion and cytokine secretion but cannot instruct Th1/Th2 fate acquisition | Q33356044 | ||
| The vacuolar ATPase is required for physiological as well as pathological activation of the Notch receptor | Q33840072 | ||
| Notch signaling in T cell development | Q33860554 | ||
| Ligand endocytosis drives receptor dissociation and activation in the Notch pathway | Q33892395 | ||
| Presenilin-dependent gamma-secretase activity modulates thymocyte development | Q33930862 | ||
| γ-secretase-dependent cleavage initiates notch signaling from the plasma membrane | Q34057805 | ||
| Transport vesicle uncoating: it's later than you think | Q34058499 | ||
| The endocytic protein alpha-Adaptin is required for numb-mediated asymmetric cell division in Drosophila | Q34145953 | ||
| Genetic analyses of adaptin function from yeast to mammals. | Q34594223 | ||
| An invitation to T and more: notch signaling in lymphopoiesis | Q34619778 | ||
| When cell biology meets development: endocytic regulation of signaling pathways | Q34671656 | ||
| The role of Notch signaling during hematopoietic lineage commitment | Q34941712 | ||
| kuzbanian-mediated cleavage of Drosophila Notch | Q35005131 | ||
| Differential surface expression of ADAM10 and ADAM17 on human T lymphocytes and tumor cells | Q35018592 | ||
| T cells develop normally in the absence of both Deltex1 and Deltex2 | Q35131705 | ||
| A voltage-gated calcium channel regulates lysosomal fusion with endosomes and autophagosomes and is required for neuronal homeostasis | Q35219922 | ||
| Defective downregulation of receptor tyrosine kinases in cancer | Q35824123 | ||
| DSL ligand endocytosis physically dissociates Notch1 heterodimers before activating proteolysis can occur | Q36117781 | ||
| Control of peripheral tolerance by regulatory T cell-intrinsic Notch signaling. | Q36199919 | ||
| The requirement for Notch signaling at the beta-selection checkpoint in vivo is absolute and independent of the pre-T cell receptor. | Q36227978 | ||
| Ligand-Independent Mechanisms of Notch Activity | Q36236844 | ||
| Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles | Q36366728 | ||
| Endosomal entry regulates Notch receptor activation in Drosophila melanogaster | Q36492053 | ||
| Distinct TCR signaling pathways drive proliferation and cytokine production in T cells | Q36625346 | ||
| Notch1 and TGFbeta1 cooperatively regulate Foxp3 expression and the maintenance of peripheral regulatory T cells | Q36843721 | ||
| Delta-like 4 is the essential, nonredundant ligand for Notch1 during thymic T cell lineage commitment. | Q36946535 | ||
| Notch simultaneously orchestrates multiple helper T cell programs independently of cytokine signals. | Q37146430 | ||
| The vacuolar proton pump, V-ATPase, is required for notch signaling and endosomal trafficking in Drosophila | Q37378404 | ||
| Notch subunit heterodimerization and prevention of ligand-independent proteolytic activation depend, respectively, on a novel domain and the LNR repeats | Q37574133 | ||
| Non-Canonical Notch Signaling Drives Activation and Differentiation of Peripheral CD4(+) T Cells. | Q37578833 | ||
| Tickets to ride: selecting cargo for clathrin-regulated internalization. | Q37583575 | ||
| Ion flux and the function of endosomes and lysosomes: pH is just the start: the flux of ions across endosomal membranes influences endosome function not only through regulation of the luminal pH. | Q37817875 | ||
| Notch signaling: simplicity in design, versatility in function | Q37914480 | ||
| Notch in T Cell Differentiation: All Things Considered | Q38652678 | ||
| T cell migration, search strategies and mechanisms. | Q38725372 | ||
| Mechanical Allostery: Evidence for a Force Requirement in the Proteolytic Activation of Notch | Q38866592 | ||
| Pharmacologic inhibition of vacuolar H+ ATPase reduces physiologic and oncogenic Notch signaling | Q39048013 | ||
| The mazy case of Notch and immunoregulatory cells. | Q39178393 | ||
| Distinct spatial and molecular features of notch pathway assembly in regulatory T cells | Q39308967 | ||
| Selective use of ADAM10 and ADAM17 in activation of Notch1 signaling | Q39808768 | ||
| Dynamic regulation of notch 1 and notch 2 surface expression during T cell development and activation revealed by novel monoclonal antibodies | Q39929085 | ||
| Notch1 signaling and regulatory T cell function | Q40010266 | ||
| Ligand-activated Notch undergoes DTX4-mediated ubiquitylation and bilateral endocytosis before ADAM10 processing. | Q40173860 | ||
| Leukemia-associated mutations within the NOTCH1 heterodimerization domain fall into at least two distinct mechanistic classes | Q40273258 | ||
| Aph-1 interacts at the cell surface with proteins in the active gamma-secretase complex and membrane-tethered Notch. | Q40457394 | ||
| Gamma-secretase exists on the plasma membrane as an intact complex that accepts substrates and effects intramembrane cleavage | Q40486950 | ||
| Monoubiquitination and endocytosis direct gamma-secretase cleavage of activated Notch receptor | Q40538132 | ||
| Notch 1 signaling regulates peripheral T cell activation | Q40566978 | ||
| Cutting edge: protective effects of notch-1 on TCR-induced apoptosis. | Q40978448 | ||
| PKCθ links proximal T cell and Notch signaling through localized regulation of the actin cytoskeleton | Q42321322 | ||
| Notch1 endocytosis is induced by ligand and is required for signal transduction. | Q42818799 | ||
| TCR-mediated Notch signaling regulates proliferation and IFN-gamma production in peripheral T cells | Q44576462 | ||
| Notch activity influences the alphabeta versus gammadelta T cell lineage decision | Q45345198 | ||
| Deficient T cell fate specification in mice with an induced inactivation of Notch1. | Q45345200 | ||
| An activated form of Notch influences the choice between CD4 and CD8 T cell lineages | Q46109980 | ||
| Nicastrin functions as a gamma-secretase-substrate receptor | Q46646587 | ||
| Drosophila Nedd4 regulates endocytosis of notch and suppresses its ligand-independent activation | Q47070716 | ||
| Cytosolic interaction between deltex and Notch ankyrin repeats implicates deltex in the Notch signaling pathway. | Q47071878 | ||
| Drosophila HOPS and AP-3 complex genes are required for a Deltex-regulated activation of notch in the endosomal trafficking pathway | Q47071885 | ||
| The metalloprotease-disintegrin Kuzbanian participates in Notch activation during growth and patterning of Drosophila imaginal discs | Q47072430 | ||
| Novel TCR-Mediated Mechanisms of Notch Activation and Signaling. | Q47232433 | ||
| Epsin-Dependent Ligand Endocytosis Activates Notch by Force. | Q47341755 | ||
| Delta1-Notch3 interactions bias the functional differentiation of activated CD4+ T cells | Q47438852 | ||
| Regulation of alphabeta/gammadelta T cell lineage commitment and peripheral T cell responses by Notch/RBP-J signaling | Q47607371 | ||
| Instruction of distinct CD4 T helper cell fates by different notch ligands on antigen-presenting cells | Q47619638 | ||
| Notch signaling augments T cell responsiveness by enhancing CD25 expression | Q47640384 | ||
| P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P921 | main subject | cell | Q7868 |
| signal transduction | Q828130 | ||
| transcription factor | Q407384 | ||
| membrane protein | Q423042 | ||
| hemic and immune systems | Q70202933 | ||
| P304 | page(s) | 1230 | |
| P577 | publication date | 2018-06-01 | |
| P1433 | published in | Frontiers in Immunology | Q27723748 |
| P1476 | title | A Review of Notch Processing With New Insights Into Ligand-Independent Notch Signaling in T-Cells | |
| P478 | volume | 9 |
| Q64241193 | Adenosine A2A Receptor Stimulation Inhibits TCR-Induced Notch1 Activation in CD8+T-Cells |
| Q92995778 | Bidirectional linkage between the B-cell receptor and NOTCH1 in chronic lymphocytic leukemia and in Richter's syndrome: therapeutic implications |
| Q95840974 | CD28 Signaling Drives Notch Ligand Expression on CD4 T Cells |
| Q92186299 | Disruption of NOTCH signaling by a small molecule inhibitor of the transcription factor RBPJ |
| Q89916811 | Engineering Cellular Biosensors with Customizable Antiviral Responses Targeting Hepatitis B Virus |
| Q98467304 | IFN signaling and neutrophil degranulation transcriptional signatures are induced during SARS-CoV-2 infection |
| Q107547988 | IFN signaling and neutrophil degranulation transcriptional signatures are induced during SARS-CoV-2 infection |
| Q89771857 | Insulin-dependent Non-canonical Activation of Notch in Drosophila: A Story of Notch-Induced Muscle Stem Cell Proliferation |
| Q92409386 | Modulation of Nerve Cell Differentiation: Role of Polyphenols and of Contactin Family Components |
| Q100415796 | Molecular signatures of anthroponotic cutaneous leishmaniasis in the lesions of patients infected with Leishmania tropica |
| Q99248397 | NOTCH3 signaling is essential for NF-κB activation in TLR-activated macrophages |
| Q90631800 | Notch3 in Development, Health and Disease |
| Q90608633 | Synthetic immunity by remote control |
| Q104135130 | Targeting Notch in oncology: the path forward |
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