Delta-like ligand 4 identifies a previously uncharacterized population of inflammatory dendritic cells that plays important roles in eliciting allogeneic T cell responses in mice

scientific article published on 25 February 2013

Delta-like ligand 4 identifies a previously uncharacterized population of inflammatory dendritic cells that plays important roles in eliciting allogeneic T cell responses in mice is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.4049/JIMMUNOL.1202820
P932PMC publication ID3608722
P698PubMed publication ID23440416
P5875ResearchGate publication ID235730017

P2093author name stringShan He
Yi Zhang
Hideo Yagita
Shin Mineishi
Yajun Guo
Fang Xie
Koji Kato
Qing Tong
Izumi Mochizuki
Kazuhiro Mochizuki
Yongnian Liu
P2860cites workHistone deacetylase inhibition modulates indoleamine 2,3-dioxygenase–dependent DC functions and regulates experimental graft-versus-host disease in miceQ24288997
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Blood monocytes consist of two principal subsets with distinct migratory propertiesQ29614286
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Acute graft-vs-host disease: pathobiology and managementQ33940061
Gene regulation and chromatin remodeling by IL-12 and type I IFN in programming for CD8 T cell effector function and memoryQ33946269
In vivo conversion of BM plasmacytoid DC into CD11b+ conventional DC during virus infectionQ33964570
Advances in graft-versus-host disease biology and therapyQ34031916
Delta4, an endothelial specific notch ligand expressed at sites of physiological and tumor angiogenesisQ34110003
Plasmacytoid dendritic cells: one-trick ponies or workhorses of the immune system?Q34149930
Notch Ligand Delta-Like 4 Regulates Development and Pathogenesis of Allergic Airway Responses by Modulating IL-2 Production and Th2 ImmunityQ34306829
Intrasplenic steady-state dendritic cell precursors that are distinct from monocytesQ34522666
Bone marrow myeloid-derived suppressor cells (MDSCs) inhibit graft-versus-host disease (GVHD) via an arginase-1-dependent mechanism that is up-regulated by interleukin-13Q34541778
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Steady-state and inflammatory dendritic-cell developmentQ34591334
Graft-versus-leukemia effects of transplantation and donor lymphocytesQ34887477
Delta-like ligand 4 regulates central nervous system T cell accumulation during experimental autoimmune encephalomyelitisQ35175775
Profound depletion of host conventional dendritic cells, plasmacytoid dendritic cells, and B cells does not prevent graft-versus-host disease inductionQ35884088
Regulation of lymphoid development, differentiation, and function by the Notch pathway.Q36072476
CD8- DCs induce IL-12-independent Th1 differentiation through Delta 4 Notch-like ligand in response to bacterial LPSQ36229524
Prevention of acute graft-versus-host disease by blocking T-cell entry to secondary lymphoid organsQ36478455
Induction of tumor immunity following allogeneic stem cell transplantationQ36490755
Depletion of host Langerhans cells before transplantation of donor alloreactive T cells prevents skin graft-versus-host diseaseQ36505142
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TLR9 regulates the mycobacteria-elicited pulmonary granulomatous immune response in mice through DC-derived Notch ligand delta-like 4Q37036047
Demystifying the development of dendritic cell subtypes, a littleQ37139265
The different faces of Notch in T-helper-cell differentiationQ37376021
Acute graft-versus-host disease: from the bench to the bedsideQ37420496
Haploinsufficiency of delta-like 4 ligand results in embryonic lethality due to major defects in arterial and vascular development.Q37594746
Bone marrow plasmacytoid dendritic cells can differentiate into myeloid dendritic cells upon virus infection.Q37684743
Deciphering the transcriptional network of the dendritic cell lineageQ37700905
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Notch and inflammatory T-cell response: new developments and challengesQ37952793
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Notch2 signaling is required for potent antitumor immunity in vivo.Q39721274
Preterminal host dendritic cells in irradiated mice prime CD8+ T cell-mediated acute graft-versus-host diseaseQ39737912
Jagged1 suppresses collagen-induced arthritis by indirectly providing a negative signal in CD8+ T cells.Q39876476
Role of ephrinB2 in nonproductive angiogenesis induced by Delta-like 4 blockadeQ39883638
Suppression of Th2 cell development by Notch ligands Delta1 and Delta4Q41962999
Graft-versus-host disease prevents the maturation of plasmacytoid dendritic cellsQ43825047
APCs in the liver and spleen recruit activated allogeneic CD8+ T cells to elicit hepatic graft-versus-host diseaseQ44241989
Recipient nonhematopoietic antigen-presenting cells are sufficient to induce lethal acute graft-versus-host diseaseQ44925138
Notch2 integrates signaling by the transcription factors RBP-J and CREB1 to promote T cell cytotoxicity.Q45345853
Ameliorating effects of anti-Dll4 mAb on Theiler's murine encephalomyelitis virus-induced demyelinating diseaseQ45373997
Host dendritic cells alone are sufficient to initiate acute graft-versus-host diseaseQ47371499
Instruction of distinct CD4 T helper cell fates by different notch ligands on antigen-presenting cellsQ47619638
Differential regulation of splenic CD8- dendritic cells and marginal zone B cells by Notch ligands.Q50620064
Identification of CCR9- murine plasmacytoid DC precursors with plasticity to differentiate into conventional DCs.Q50632368
Delta-like 1 is essential for the maintenance of marginal zone B cells in normal mice but not in autoimmune mice.Q50654232
Dendritic cell-activated CD44hiCD8+ T cells are defective in mediating acute graft-versus-host disease but retain graft-versus-leukemia activity.Q52002812
An experimental model of idiopathic pneumonia syndrome after bone marrow transplantation: I. The roles of minor H antigens and endotoxinQ71881409
Acute graft-versus-host disease does not require alloantigen expression on host epitheliumQ74221421
Prevention of graft versus host disease by inactivation of host antigen-presenting cellsQ78016071
Donor APCs are required for maximal GVHD but not for GVLQ80402910
Distinct roles for donor- and host-derived antigen-presenting cells and costimulatory molecules in murine chronic graft-versus-host disease: requirements depend on target organQ80952289
A crucial role for antigen-presenting cells and alloantigen expression in graft-versus-leukemia responsesQ81357571
JAGGED1 and delta1 differentially regulate the outcome of experimental autoimmune encephalomyelitisQ81464305
Notch signaling in the immune systemQ82881379
Plasmacytoid dendritic cells prime alloreactive T cells to mediate graft-versus-host disease as antigen-presenting cellsQ83187973
Expression of Notch receptors and ligands on immature and mature T cellsQ83396424
Graft-versus-host diseaseQ83468020
Recipient plasmacytoid DCs are not required to prime allogeneic T-cell responses after BMTQ84004827
Regulation of T cell activation by Notch ligand, DLL4, promotes IL-17 production and Rorc activationQ95816367
P433issue7
P407language of work or nameEnglishQ1860
P921main subjectdendritic cellQ506253
P304page(s)3772-3782
P577publication date2013-02-25
P1433published inJournal of ImmunologyQ3521441
P1476titleDelta-like ligand 4 identifies a previously uncharacterized population of inflammatory dendritic cells that plays important roles in eliciting allogeneic T cell responses in mice
P478volume190