review article | Q7318358 |
scholarly article | Q13442814 |
P2093 | author name string | Bor-Luen Chiang | |
Chiao-Juno Chiu | |||
Miao-Tzu Huang | |||
P2860 | cites work | The notch ligands Dll4 and Jagged1 have opposing effects on angiogenesis | Q45345843 |
Overexpression of the Notch ligand, Jagged-1, induces alloantigen-specific human regulatory T cells | Q45863413 | ||
Heart disease modelling adds a Notch to its belt. | Q45951426 | ||
Gamma-secretase inhibitor reduces allergic pulmonary inflammation by modulating Th1 and Th2 responses. | Q46113876 | ||
Mechanisms of allergen immunotherapy for inhaled allergens and predictive biomarkers | Q47314389 | ||
Instruction of distinct CD4 T helper cell fates by different notch ligands on antigen-presenting cells | Q47619638 | ||
Notch Signaling: Linking Embryonic Lung Development and Asthmatic Airway Remodeling | Q47660302 | ||
Antibody therapy for the management of severe asthma with eosinophilic inflammation | Q47773104 | ||
Allergen exposure of mouse airways evokes remodeling of both bronchi and large pulmonary vessels | Q47921757 | ||
Anti-Dll4 Antibody Inhibits the Differentiation of Th17 Cells in Asthmatic Mice | Q47947293 | ||
Notch Balances Th17 and Induced Regulatory T Cell Functions in Dendritic Cells by Regulating Aldh1a2 Expression | Q47988873 | ||
Beyond epithelial-to-mesenchymal transition: Common suppression of differentiation programs underlies epithelial barrier dysfunction in mild, moderate, and severe asthma. | Q48298703 | ||
Dynamic Ligand Discrimination in the Notch Signaling Pathway. | Q49344558 | ||
The CD46-Jagged1 interaction is critical for human TH1 immunity | Q24301407 | ||
Regulation of Notch1 and Dll4 by vascular endothelial growth factor in arterial endothelial cells: implications for modulating arteriogenesis and angiogenesis | Q24540581 | ||
Sequence of the notch locus of Drosophila melanogaster: relationship of the encoded protein to mammalian clotting and growth factors | Q24617135 | ||
Delta-like ligand 4 (Dll4) is induced by VEGF as a negative regulator of angiogenic sprouting | Q24685542 | ||
Angiogenesis in the pathogenesis of inflammatory joint and lung diseases | Q24805418 | ||
Resolution of airway inflammation and hyperreactivity after in vivo transfer of CD4+CD25+ regulatory T cells is interleukin 10 dependent. | Q25255561 | ||
γ-Secretase inhibitors and modulators | Q26830462 | ||
Non-canonical Notch signaling: emerging role and mechanism | Q26863550 | ||
Notch signaling as a novel regulator of metabolism | Q27014152 | ||
Severe asthma: anti-IgE or anti-IL-5? | Q28071832 | ||
Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain | Q28273268 | ||
Fringe glycosyltransferases differentially modulate Notch1 proteolysis induced by Delta1 and Jagged1 | Q28509366 | ||
Activation of c-Kit in dendritic cells regulates T helper cell differentiation and allergic asthma | Q28584858 | ||
Nuclear access and action of notch in vivo | Q28646384 | ||
The canonical Notch signaling pathway: unfolding the activation mechanism | Q29547725 | ||
A microbial symbiosis factor prevents intestinal inflammatory disease | Q29614263 | ||
Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis | Q29614939 | ||
The microbial metabolites, short-chain fatty acids, regulate colonic Treg cell homeostasis | Q29616351 | ||
Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells | Q29618126 | ||
Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation | Q29620116 | ||
Interleukin 10 attenuates neointimal proliferation and inflammation in aortic allografts by a heme oxygenase-dependent pathway | Q33775328 | ||
Extracellular matrix, inflammation, and the angiogenic response | Q33795730 | ||
Nucleotide sequence from the neurogenic locus notch implies a gene product that shares homology with proteins containing EGF-like repeats | Q34195800 | ||
Enhancing the understanding of asthma | Q34216556 | ||
A critical role for regulatory T cell-mediated control of inflammation in the absence of commensal microbiota | Q34243359 | ||
Notch and the awesome power of genetics | Q34287433 | ||
Airway wall remodelling and hyperresponsiveness: modelling remodelling in vitro and in vivo. | Q34305525 | ||
Notch Ligand Delta-Like 4 Regulates Development and Pathogenesis of Allergic Airway Responses by Modulating IL-2 Production and Th2 Immunity | Q34306829 | ||
Intrinsic activity of the Lin-12 and Notch intracellular domains in vivo | Q34352020 | ||
A phase I dose escalation and expansion study of the anticancer stem cell agent demcizumab (anti-DLL4) in patients with previously treated solid tumors. | Q34443946 | ||
Up-regulation of delta-like 4 ligand in human tumor vasculature and the role of basal expression in endothelial cell function | Q34456711 | ||
Up-regulation of the Notch ligand Delta-like 4 inhibits VEGF-induced endothelial cell function | Q34458950 | ||
A role for eosinophils in airway remodelling in asthma | Q34550355 | ||
Endothelial signalling by the Notch ligand Delta-like 4 restricts angiogenesis. | Q34605909 | ||
Notch signalling limits angiogenic cell behaviour in developing zebrafish arteries | Q34607158 | ||
Airway remodelling in the pathogenesis of asthma | Q34607541 | ||
Mast cells can promote the development of multiple features of chronic asthma in mice | Q34619598 | ||
Asthma: an epidemic of dysregulated immunity | Q34765268 | ||
Notch signaling in vascular development | Q35077358 | ||
Gut microbiota metabolism of dietary fiber influences allergic airway disease and hematopoiesis | Q35081904 | ||
Type 2 inflammation in asthma--present in most, absent in many | Q35322784 | ||
Influence of intestinal bacteria on induction of regulatory T cells: lessons from a transfer model of colitis | Q35597887 | ||
The Notch ligand Delta-like 4 negatively regulates endothelial tip cell formation and vessel branching. | Q35652503 | ||
Notch regulation of lymphocyte development and function. | Q35676281 | ||
Inhibition of Dll4-mediated signaling induces proliferation of immature vessels and results in poor tissue perfusion | Q35828791 | ||
Notch ligand delta-like 4 blockade alleviates experimental autoimmune encephalomyelitis by promoting regulatory T cell development | Q35848780 | ||
IL-17A produced by αβ T cells drives airway hyper-responsiveness in mice and enhances mouse and human airway smooth muscle contraction | Q35874754 | ||
Dll4-Notch signaling in Flt3-independent dendritic cell development and autoimmunity in mice | Q35946087 | ||
γ-Secretase Inhibitor Alleviates Acute Airway Inflammation of Allergic Asthma in Mice by Downregulating Th17 Cell Differentiation | Q35962890 | ||
Anti-IL-5 treatment reduces deposition of ECM proteins in the bronchial subepithelial basement membrane of mild atopic asthmatics | Q36001230 | ||
Notch system in the linkage of innate and adaptive immunity | Q36055999 | ||
Metabolic reprogramming induces resistance to anti-NOTCH1 therapies in T cell acute lymphoblastic leukemia | Q36137651 | ||
Vascular endothelial growth factor (VEGF) induces remodeling and enhances TH2-mediated sensitization and inflammation in the lung. | Q36209876 | ||
Reversal of airway hyperresponsiveness by induction of airway mucosal CD4+CD25+ regulatory T cells | Q36228134 | ||
Notch ligand Delta-like 4 regulates disease pathogenesis during respiratory viral infections by modulating Th2 cytokines | Q36229204 | ||
Recent insights into the role of Notch signaling in tumorigenesis | Q36314431 | ||
TLR4 signaling in stromal cells is critical for the initiation of allergic Th2 responses to inhaled antigen. | Q50784151 | ||
Intestinal commensal bacteria promote T cell hyporesponsiveness and down-regulate the serum antibody responses induced by dietary antigen. | Q51045890 | ||
Type 2 cytokines in the pathogenesis of sustained airway dysfunction and airway remodeling in mice. | Q51636510 | ||
Notch signaling confers antigen-presenting cell functions on mast cells. | Q51782619 | ||
Notch ligand Delta-like4 inhibits the development of murine experimental allergic conjunctivitis. | Q51784180 | ||
Anti-DLL4 has broad spectrum activity in pancreatic cancer dependent on targeting DLL4-Notch signaling in both tumor and vasculature cells. | Q52629451 | ||
Cutting edge: Plasmacytoid dendritic cells induce IL-10 production in T cells via the Delta-like-4/Notch axis. | Q52906696 | ||
Jagged1 on dendritic cells and Notch on CD4+ T cells initiate lung allergic responsiveness by inducing IL-4 production. | Q53378578 | ||
Is IgE or eosinophils the key player in allergic asthma pathogenesis? Are we asking the right question? | Q55370774 | ||
Impaired regulatory T cell function in germ-free mice | Q56901969 | ||
Increased surface expression of NOTCH on memory T cells in peripheral blood from asthma patients | Q57184851 | ||
NK Cell Deficiency Predisposes to Viral-Induced Th2-Type Allergic Inflammation via Epithelial-Derived IL-25 | Q57966252 | ||
Acute Allergen-Induced Airway Remodeling in Atopic Asthma | Q57966293 | ||
Boosting airway T-regulatory cells by gastrointestinal stimulation as a strategy for asthma control | Q58385177 | ||
Jagged gives an edge to TH1 cells | Q62002305 | ||
Notch-Hes1 pathway is required for the development of IL-17-producing T cells | Q62735634 | ||
IL-23 and Th17 Cells Enhance Th2-Cell–mediated Eosinophilic Airway Inflammation in Mice | Q62735710 | ||
Expression of vascular endothelial growth factor, basic fibroblast growth factor, and angiogenin immunoreactivity in asthmatic airways and its relationship to angiogenesis | Q73431447 | ||
Increased vascularity of the bronchial mucosa in mild asthma | Q73528703 | ||
Bronchial angiogenesis in severe glucocorticoid-dependent asthma | Q73966635 | ||
Linked suppression in peripheral T cell tolerance to the house dust mite derived allergen Der p 1 | Q77388868 | ||
Remodeling and airway hyperresponsiveness but not cellular inflammation persist after allergen challenge in asthma | Q79711349 | ||
JAGGED1 and delta1 differentially regulate the outcome of experimental autoimmune encephalomyelitis | Q81464305 | ||
Epithelial cell-intrinsic Notch signaling plays an essential role in the maintenance of gut immune homeostasis | Q83328392 | ||
Regulatory T cells negatively regulate neovasculature of airway remodeling via DLL4-Notch signaling | Q84558490 | ||
Asthma and allergy: Complementing the IL-17 axis in asthma | Q85108020 | ||
Asthma and allergy: An IFNγ bias in severe asthma | Q85619272 | ||
A first-in-human phase 1a study of the bispecific anti-DLL4/anti-VEGF antibody navicixizumab (OMP-305B83) in patients with previously treated solid tumors | Q91528336 | ||
The use of biologics for immune modulation in allergic disease | Q92435887 | ||
Regulation of T cell activation by Notch ligand, DLL4, promotes IL-17 production and Rorc activation | Q95816367 | ||
Jagged 1 Rescues the Duchenne Muscular Dystrophy Phenotype | Q36344905 | ||
CD4+CD25+ T cells protect against experimentally induced asthma and alter pulmonary dendritic cell phenotype and function | Q36403998 | ||
Different assemblies of Notch receptors coordinate the distribution of the major bronchial Clara, ciliated and neuroendocrine cells | Q36432890 | ||
Notch regulates IL-10 production by T helper 1 cells | Q36491342 | ||
Essential role of Notch signaling in effector memory CD8+ T cell-mediated airway hyperresponsiveness and inflammation. | Q36639992 | ||
Blockade of individual Notch ligands and receptors controls graft-versus-host disease | Q36733439 | ||
Notch signaling in blood vessels: who is talking to whom about what? | Q36843651 | ||
TLR9 regulates the mycobacteria-elicited pulmonary granulomatous immune response in mice through DC-derived Notch ligand delta-like 4 | Q37036047 | ||
Obesity and Asthma: Microbiome-Metabolome Interactions | Q37088255 | ||
Epithelial Notch signaling regulates lung alveolar morphogenesis and airway epithelial integrity | Q37126807 | ||
Mature human eosinophils express functional Notch ligands mediating eosinophil autocrine regulation | Q37143667 | ||
The different faces of Notch in T-helper-cell differentiation | Q37376021 | ||
Notch Ligand DLL4 Alleviates Allergic Airway Inflammation via Induction of a Homeostatic Regulatory Pathway | Q37681701 | ||
Canonical and non-canonical Notch ligands | Q37785194 | ||
Mechanism and significance of cis-inhibition in Notch signalling. | Q37826900 | ||
Pathophysiology of allergic inflammation | Q37891126 | ||
Asthma phenotypes and the use of biologic medications in asthma and allergic disease: the next steps toward personalized care | Q38348052 | ||
Cellular and molecular mechanisms of inflammation-induced angiogenesis | Q38433996 | ||
Anti-DLL4, a cancer therapeutic with multiple mechanisms of action | Q38540667 | ||
Notch in T Cell Differentiation: All Things Considered | Q38652678 | ||
Gamma secretase inhibitors: a patent review (2013 - 2015). | Q38738605 | ||
γ-Secretase inhibitors in cancer clinical trials are pharmacologically and functionally distinct | Q38766437 | ||
Notch signaling in lung diseases: focus on Notch1 and Notch3. | Q38845270 | ||
Notch signalling in context | Q38923306 | ||
JAG1-Mediated Notch Signaling Regulates Secretory Cell Differentiation of the Human Airway Epithelium | Q39742269 | ||
Sequential Notch activation regulates ventricular chamber development | Q39752995 | ||
Inhibition of Dll4 signalling inhibits tumour growth by deregulating angiogenesis | Q40191484 | ||
Blockade of Dll4 inhibits tumour growth by promoting non-productive angiogenesis | Q40191493 | ||
Notch Ligand Delta-like 4 Promotes Regulatory T Cell Identity in Pulmonary Viral Infection | Q40375954 | ||
PTTG1IP and MAML3, novel genomewide association study genes for severity of hyperresponsiveness in adult asthma | Q40552310 | ||
Bronchial biopsies in asthma. An ultrastructural, quantitative study and correlation with hyperreactivity. | Q40768651 | ||
Fringe differentially modulates Jagged1 and Delta1 signalling through Notch1 and Notch2. | Q40862987 | ||
Notch signaling mediates granulocyte-macrophage colony-stimulating factor priming-induced transendothelial migration of human eosinophils | Q41110691 | ||
The immunology of asthma | Q41673436 | ||
Suppression of Th2 cell development by Notch ligands Delta1 and Delta4 | Q41962999 | ||
A Notch ligand, Delta-like 1 functions as an adhesion molecule for mast cells. | Q42814849 | ||
Inhaled corticosteroids decrease vascularity of the bronchial mucosa in patients with asthma | Q43650596 | ||
Dysfunction and remodeling of the mouse airway persist after resolution of acute allergen-induced airway inflammation | Q44191932 | ||
Th17/Treg dysregulation in allergic asthmatic children is associated with elevated notch expression | Q45058212 | ||
P275 | copyright license | Creative Commons Attribution | Q6905323 |
P6216 | copyright status | copyrighted | Q50423863 |
P433 | issue | 14 | |
P921 | main subject | asthma | Q35869 |
signal transduction | Q828130 | ||
P577 | publication date | 2019-07-17 | |
P1433 | published in | International Journal of Molecular Sciences | Q3153277 |
P1476 | title | Multi-Faceted Notch in Allergic Airway Inflammation | |
P478 | volume | 20 |
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