| scholarly article | Q13442814 |
| P356 | DOI | 10.1038/S41577-018-0068-5 |
| P698 | PubMed publication ID | 30242265 |
| P50 | author | Bart Lambrecht | Q18402373 |
| P2093 | author name string | Hamida Hammad | |
| Matthias Vanderkerken | |||
| P2860 | cites work | Regulation of adult hematopoiesis by the a disintegrin and metalloproteinase 10 (ADAM10) | Q86757375 |
| The TspanC8 subgroup of tetraspanins interacts with A disintegrin and metalloprotease 10 (ADAM10) and regulates its maturation and cell surface expression | Q24300299 | ||
| TspanC8 tetraspanins regulate ADAM10/Kuzbanian trafficking and promote Notch activation in flies and mammals | Q24301578 | ||
| The disintegrin/metalloprotease ADAM 10 is essential for Notch signalling but not for alpha-secretase activity in fibroblasts | Q24307875 | ||
| Structural determinants of the ADAM inhibition by TIMP-3: crystal structure of the TACE-N-TIMP-3 complex | Q24315151 | ||
| Extracellular signal-regulated kinase phosphorylates tumor necrosis factor alpha-converting enzyme at threonine 735: a potential role in regulated shedding. | Q24531403 | ||
| ADAM, a novel family of membrane proteins containing A Disintegrin And Metalloprotease domain: multipotential functions in cell-cell and cell-matrix interactions | Q24651463 | ||
| ADAM and ADAMTS Family Proteins and Snake Venom Metalloproteinases: A Structural Overview | Q26747656 | ||
| Phosphatidylserine exposure is required for ADAM17 sheddase function | Q27317119 | ||
| Identification of SH3 domain proteins interacting with the cytoplasmic tail of the a disintegrin and metalloprotease 10 (ADAM10) | Q27318461 | ||
| Genome-wide CRISPR screen reveals novel host factors required for Staphylococcus aureus α-hemolysin-mediated toxicity. | Q27322587 | ||
| Discovery of a new selective inhibitor of A Disintegrin And Metalloprotease 10 (ADAM-10) able to reduce the shedding of NKG2D ligands in Hodgkin's lymphoma cell models | Q27704009 | ||
| A metalloproteinase disintegrin that releases tumour-necrosis factor-alpha from cells | Q28119154 | ||
| A novel proteolytic cleavage involved in Notch signaling: the role of the disintegrin-metalloprotease TACE | Q28139998 | ||
| A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain | Q28141707 | ||
| Association of the ADAM33 gene with asthma and bronchial hyperresponsiveness | Q28214089 | ||
| Notch ligand endocytosis: mechanistic basis of signaling activity | Q28258972 | ||
| Soluble ADAM33 initiates airway remodeling to promote susceptibility for allergic asthma in early life | Q28277648 | ||
| The ADAM metalloproteinases | Q28292696 | ||
| Mechanism and biological significance of CD44 cleavage | Q28298070 | ||
| Molecular insights into the multilayered regulation of ADAM17: The role of the extracellular region | Q39344646 | ||
| Scissor sisters: regulation of ADAM10 by the TspanC8 tetraspanins. | Q39376860 | ||
| Regulation of the trafficking and the function of the metalloprotease ADAM10 by tetraspanins. | Q39422025 | ||
| An arginine stretch limits ADAM10 exit from the endoplasmic reticulum | Q40074672 | ||
| ADAM10 and Notch1 on murine dendritic cells control the development of type 2 immunity and IgE production. | Q40119336 | ||
| Ligand-activated Notch undergoes DTX4-mediated ubiquitylation and bilateral endocytosis before ADAM10 processing. | Q40173860 | ||
| ADAM10-Interacting Tetraspanins Tspan5 and Tspan17 Regulate VE-Cadherin Expression and Promote T Lymphocyte Transmigration | Q40178318 | ||
| ADAM10 inhibition of human CD30 shedding increases specificity of targeted immunotherapy in vitro | Q40185345 | ||
| Antigen recognition induces phosphatidylserine exposure on the cell surface of human CD8+ T cells | Q40243201 | ||
| ADAM10 new selective inhibitors reduce NKG2D ligand release sensitizing Hodgkin lymphoma cells to NKG2D-mediated killing | Q40596798 | ||
| Dissecting the role of ADAM10 as a mediator of Staphylococcus aureus α-toxin action | Q40686973 | ||
| Myeloid A disintegrin and metalloproteinase domain 10 deficiency modulates atherosclerotic plaque composition by shifting the balance from inflammation toward fibrosis. | Q41467610 | ||
| Delta-like 1 is necessary for the generation of marginal zone B cells but not T cells in vivo | Q28509550 | ||
| Deficiency of the Metalloproteinase-Disintegrin ADAM8 Is Associated with Thymic Hyper-Cellularity | Q28512812 | ||
| The metalloprotease-disintegrin ADAM8 is essential for the development of experimental asthma | Q28587244 | ||
| Absence of marginal zone B cells in Pyk-2-deficient mice defines their role in the humoral response | Q28590125 | ||
| Notch-RBP-J signaling is involved in cell fate determination of marginal zone B cells | Q28594415 | ||
| Crystal Structure of a Full-Length Human Tetraspanin Reveals a Cholesterol-Binding Pocket | Q30395581 | ||
| Adam17-dependent shedding limits early neutrophil influx but does not alter early monocyte recruitment to inflammatory sites | Q30425907 | ||
| Asynchronous combinatorial action of four regulatory factors activates Bcl11b for T cell commitment | Q30787663 | ||
| ERK-mediated phosphorylation of Thr735 in TNFalpha-converting enzyme and its potential role in TACE protein trafficking | Q33216029 | ||
| ADAM17 deletion in thymic epithelial cells alters aire expression without affecting T cell developmental progression | Q33728091 | ||
| ADAM10 is essential for Notch2-dependent marginal zone B cell development and CD23 cleavage in vivo | Q33730084 | ||
| Notch2 is preferentially expressed in mature B cells and indispensable for marginal zone B lineage development | Q34197865 | ||
| Immune inhibitory molecules LAG-3 and PD-1 synergistically regulate T-cell function to promote tumoral immune escape | Q34241893 | ||
| Tumor necrosis factor signaling requires iRhom2 to promote trafficking and activation of TACE | Q34247194 | ||
| iRhom2 regulation of TACE controls TNF-mediated protection against Listeria and responses to LPS | Q34247201 | ||
| Marginal zone B cells: virtues of innate-like antibody-producing lymphocytes | Q34324243 | ||
| CD23 Sheddase A disintegrin and metalloproteinase 10 (ADAM10) is also required for CD23 sorting into B cell-derived exosomes | Q34333685 | ||
| ADAM10 regulates transcription factor expression required for plasma cell function | Q34374623 | ||
| Specific fibroblastic niches in secondary lymphoid organs orchestrate distinct Notch-regulated immune responses | Q34375200 | ||
| Membrane-enabled dimerization of the intrinsically disordered cytoplasmic domain of ADAM10. | Q34526248 | ||
| TACE activation by MAPK-mediated regulation of cell surface dimerization and TIMP3 association. | Q34626693 | ||
| SAP97-mediated ADAM10 trafficking from Golgi outposts depends on PKC phosphorylation | Q34662305 | ||
| The Immunological Genome Project: networks of gene expression in immune cells. | Q34830433 | ||
| Notch signaling regulates antigen sensitivity of naive CD4+ T cells by tuning co-stimulation | Q35041145 | ||
| The extracellular regulated kinase-1 (ERK1) controls regulated alpha-secretase-mediated processing, promoter transactivation, and mRNA levels of the cellular prion protein. | Q35310087 | ||
| A Staphylococcus aureus pore-forming toxin subverts the activity of ADAM10 to cause lethal infection in mice | Q35332249 | ||
| Soluble T cell immunoglobulin mucin domain 3 is shed from CD8+ T cells by the sheddase ADAM10, is increased in plasma during untreated HIV infection, and correlates with HIV disease progression | Q35487768 | ||
| Notch2 receptor signaling controls functional differentiation of dendritic cells in the spleen and intestine. | Q35577590 | ||
| The Functional Maturation of A Disintegrin and Metalloproteinase (ADAM) 9, 10, and 17 Requires Processing at a Newly Identified Proprotein Convertase (PC) Cleavage Site | Q35583121 | ||
| Metalloproteases regulate T-cell proliferation and effector function via LAG-3 | Q35612460 | ||
| iRhoms 1 and 2 are essential upstream regulators of ADAM17-dependent EGFR signaling | Q35616369 | ||
| Identification of function for CD44 intracytoplasmic domain (CD44-ICD): modulation of matrix metalloproteinase 9 (MMP-9) transcription via novel promoter response element | Q36003640 | ||
| Notch controls the magnitude of T helper cell responses by promoting cellular longevity. | Q36061611 | ||
| Human and Murine Interleukin 23 Receptors Are Novel Substrates for A Disintegrin and Metalloproteases ADAM10 and ADAM17. | Q41510241 | ||
| Notch controls the survival of memory CD4+ T cells by regulating glucose uptake | Q41602132 | ||
| ADAM10 regulates endothelial permeability and T-Cell transmigration by proteolysis of vascular endothelial cadherin. | Q41840639 | ||
| Polo-like kinase 2, a novel ADAM17 signaling component, regulates tumor necrosis factor α ectodomain shedding | Q41903115 | ||
| A disintegrin and metalloprotease (ADAM) 10 and ADAM17 are major sheddases of T cell immunoglobulin and mucin domain 3 (Tim-3) | Q41980551 | ||
| TREM2 shedding by cleavage at the H157-S158 bond is accelerated for the Alzheimer's disease-associated H157Y variant | Q41997591 | ||
| Adam8 limits the development of allergic airway inflammation in mice. | Q42150169 | ||
| Soluble CD40-ligand (sCD40L, sCD154) plays an immunosuppressive role via regulatory T cell expansion in HIV infection. | Q42212835 | ||
| Sputum ADAM8 expression is increased in severe asthma and COPD. | Q42260613 | ||
| PKCθ links proximal T cell and Notch signaling through localized regulation of the actin cytoskeleton | Q42321322 | ||
| Macrophage ADAM17 deficiency augments CD36-dependent apoptotic cell uptake and the linked anti-inflammatory phenotype | Q43114569 | ||
| Visualization of splenic marginal zone B-cell shuttling and follicular B-cell egress. | Q43118025 | ||
| Anticancer chemotherapy inhibits MHC class I-related chain a ectodomain shedding by downregulating ADAM10 expression in hepatocellular carcinoma | Q43262193 | ||
| Soluble ligands for the NKG2D receptor are released during HIV-1 infection and impair NKG2D expression and cytotoxicity of NK cells | Q43974773 | ||
| Transitional B cells commit to marginal zone B cell fate by Taok3-mediated surface expression of ADAM10. | Q45050470 | ||
| ADAM10-Mediated ICOS Ligand Shedding on B Cells Is Necessary for Proper T Cell ICOS Regulation and T Follicular Helper Responses. | Q45065459 | ||
| The Notch regulator Numb links the Notch and TCR signaling pathways | Q45213459 | ||
| Notch activity influences the alphabeta versus gammadelta T cell lineage decision | Q45345198 | ||
| T-cell immunoglobulin and mucin domain 2 (TIM-2) is a target of ADAM10-mediated ectodomain shedding | Q45799693 | ||
| An activated form of Notch influences the choice between CD4 and CD8 T cell lineages | Q46109980 | ||
| Release of soluble CD30 after allogeneic stimulation is mediated by memory T cells and regulated by IFN-γ and IL-2. | Q46441254 | ||
| Impairment of thymocyte development by dominant-negative Kuzbanian (ADAM-10) is rescued by the Notch ligand, delta-1. | Q46768820 | ||
| Structural Basis for Regulated Proteolysis by the α-Secretase ADAM10. | Q47311068 | ||
| Epsin-Dependent Ligand Endocytosis Activates Notch by Force. | Q47341755 | ||
| Survival of resting mature B lymphocytes depends on BCR signaling via the Igalpha/beta heterodimer | Q47372605 | ||
| Regulation of alphabeta/gammadelta T cell lineage commitment and peripheral T cell responses by Notch/RBP-J signaling | Q47607371 | ||
| Instruction of distinct CD4 T helper cell fates by different notch ligands on antigen-presenting cells | Q47619638 | ||
| Delta-toxin from Clostridium perfringens perturbs intestinal epithelial barrier function in Caco-2 cell monolayers | Q47680902 | ||
| Expression and regulation of a disintegrin and metalloproteinase (ADAM) 8 in experimental asthma | Q47755798 | ||
| Tetraspanin15 regulates cellular trafficking and activity of the ectodomain sheddase ADAM10. | Q47984887 | ||
| BAFF- and TACI-Dependent Processing of BAFFR by ADAM Proteases Regulates the Survival of B Cells. | Q50453463 | ||
| The duration of antigen receptor signalling determines CD4+ versus CD8+ T-cell lineage fate. | Q51081581 | ||
| Notch signaling is necessary for adult, but not fetal, development of RORγt(+) innate lymphoid cells. | Q51854388 | ||
| ADAM10 is essential for proteolytic activation of Notch during thymocyte development. | Q51952311 | ||
| Dual functions of cell-autonomous and non-cell-autonomous ADAM10 activity in granulopoiesis. | Q53208988 | ||
| Regulated shedding of transmembrane chemokines by the disintegrin and metalloproteinase 10 facilitates detachment of adherent leukocytes. | Q53548573 | ||
| ADAM10 regulates FasL cell surface expression and modulates FasL-induced cytotoxicity and activation-induced cell death. | Q53572097 | ||
| Notch Signaling Facilitates In Vitro Generation of Cross-Presenting Classical Dendritic Cells | Q58620994 | ||
| The prognostic significance of soluble NKG2D ligands in B-cell chronic lymphocytic leukemia | Q60345328 | ||
| A ligand-induced extracellular cleavage regulates gamma-secretase-like proteolytic activation of Notch1 | Q73958442 | ||
| ADAM10 is a principal 'sheddase' of the low-affinity immunoglobulin E receptor CD23 | Q79314167 | ||
| The effects of Th2 cytokines on the expression of ADAM33 in allergen-induced chronic airway inflammation | Q84300377 | ||
| Ligand-Independent Mechanisms of Notch Activity | Q36236844 | ||
| Cleavage of Signal Regulatory Protein α (SIRPα) Enhances Inflammatory Signaling | Q36407323 | ||
| Distinct TCR signaling pathways drive proliferation and cytokine production in T cells | Q36625346 | ||
| The precursor region of a protein active in sperm-egg fusion contains a metalloprotease and a disintegrin domain: structural, functional, and evolutionary implications | Q36673157 | ||
| Interferon-γ Protects from Staphylococcal Alpha Toxin-Induced Keratinocyte Death through Apolipoprotein L1 | Q36731065 | ||
| TspanC8 tetraspanins differentially regulate the cleavage of ADAM10 substrates, Notch activation and ADAM10 membrane compartmentalization. | Q36762907 | ||
| Ectodomain Shedding of Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE-1) Is Induced by Vascular Endothelial Growth Factor A (VEGF-A) | Q36898186 | ||
| iRhom2 controls the substrate selectivity of stimulated ADAM17-dependent ectodomain shedding. | Q37010654 | ||
| A-Disintegrin and Metalloproteinase (ADAM) 17 Enzymatically Degrades Interferon-gamma | Q37215829 | ||
| The different faces of Notch in T-helper-cell differentiation | Q37376021 | ||
| Disturbed follicular architecture in B cell A disintegrin and metalloproteinase (ADAM)10 knockouts is mediated by compensatory increases in ADAM17 and TNF-α shedding | Q37393294 | ||
| IRF4 controls the positioning of mature B cells in the lymphoid microenvironments by regulating NOTCH2 expression and activity. | Q37397830 | ||
| Tetraspanin-enriched microdomains: a functional unit in cell plasma membranes | Q37587580 | ||
| The follicular versus marginal zone B lymphocyte cell fate decision | Q37621246 | ||
| Evidence of a genetic contribution to lung function decline in asthma. | Q37900722 | ||
| The role of ADAM17 in metabolic inflammation. | Q38079339 | ||
| Tetraspanin proteins promote multiple cancer stages | Q38186043 | ||
| Function of the tetraspanin molecule CD81 in B and T cells | Q38187573 | ||
| TspanC8 Tetraspanins and A Disintegrin and Metalloprotease 10 (ADAM10) Interact via Their Extracellular Regions: EVIDENCE FOR DISTINCT BINDING MECHANISMS FOR DIFFERENT TspanC8 PROTEINS. | Q38377767 | ||
| Frontline Science: Tim-3-mediated dysfunctional engulfment of apoptotic cells in SLE. | Q38654341 | ||
| Deletions in the cytoplasmic domain of iRhom1 and iRhom2 promote shedding of the TNF receptor by the protease ADAM17. | Q38822173 | ||
| Shedding of Endogenous Interleukin-6 Receptor (IL-6R) Is Governed by A Disintegrin and Metalloproteinase (ADAM) Proteases while a Full-length IL-6R Isoform Localizes to Circulating Microvesicles | Q38836137 | ||
| Extracellular Juxtamembrane Segment of ADAM17 Interacts with Membranes and Is Essential for Its Shedding Activity | Q38837058 | ||
| The tetraspanin web revisited by super-resolution microscopy | Q38852168 | ||
| Regulation of A disintegrin and metalloproteinase (ADAM) family sheddases ADAM10 and ADAM17: The emerging role of tetraspanins and rhomboids. | Q38852399 | ||
| Mechanical Allostery: Evidence for a Force Requirement in the Proteolytic Activation of Notch | Q38866592 | ||
| Subcellular localization and activation of ADAM proteases in the context of FasL shedding in T lymphocytes | Q38902955 | ||
| Post-Translational Modification Control of Innate Immunity | Q38903391 | ||
| TREM2 mutations implicated in neurodegeneration impair cell surface transport and phagocytosis | Q38978510 | ||
| Leukocytes require ADAM10 but not ADAM17 for their migration and inflammatory recruitment into the alveolar space | Q38994499 | ||
| CD154 is released from T-cells by a disintegrin and metalloproteinase domain-containing protein 10 (ADAM10) and ADAM17 in a CD40 protein-dependent manner | Q39067245 | ||
| A disintegrin and metalloproteinase 10 regulates antibody production and maintenance of lymphoid architecture | Q39132527 | ||
| LAG3 (CD223) as a cancer immunotherapy target | Q39160974 | ||
| Shedding of endogenous MHC class I-related chain molecules A and B from different human tumor entities: heterogeneous involvement of the "a disintegrin and metalloproteases" 10 and 17. | Q39176227 | ||
| P433 | issue | 12 | |
| P304 | page(s) | 745-758 | |
| P577 | publication date | 2018-12-01 | |
| P1433 | published in | Nature Reviews Immunology | Q43355 |
| P1476 | title | The emerging role of ADAM metalloproteinases in immunity | |
| P478 | volume | 18 |
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