miR-22 inhibits estrogen signaling by directly targeting the estrogen receptor alpha mRNA

scientific article

miR-22 inhibits estrogen signaling by directly targeting the estrogen receptor alpha mRNA is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1128/MCB.01875-08
P3181OpenCitations bibliographic resource ID501462
P932PMC publication ID2698751
P698PubMed publication ID19414598
P5875ResearchGate publication ID24400928

P2093author name stringDidier Picard
Deo Prakash Pandey
P2860cites workCharacterization of microRNA expression levels and their biological correlates in human cancer cell linesQ40158414
The micro-ribonucleic acid (miRNA) miR-206 targets the human estrogen receptor-alpha (ERalpha) and represses ERalpha messenger RNA and protein expression in breast cancer cell lines.Q40168734
The 3'-untranslated region of the human estrogen receptor alpha gene mediates rapid messenger ribonucleic acid turnoverQ40864729
Growth inhibition by anti-estrogens and progestins in TGF-beta-resistant and -sensitive breast-tumor cellsQ41226072
Estradiol up-regulates AUF1p45 binding to stabilizing regions within the 3'-untranslated region of estrogen receptor alpha mRNA.Q46888895
Regulation of the estrogen receptor in MCF-7 cells by estradiolQ68015751
Inefficient targeting to the endoplasmic reticulum by the signal recognition particle elicits selective defects in post-ER membrane traffickingQ79615611
A system for stable expression of short interfering RNAs in mammalian cellsQ27860875
Widespread changes in protein synthesis induced by microRNAsQ27860886
Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?Q27860893
MicroRNA signatures in human cancersQ27860962
MicroRNAs: genomics, biogenesis, mechanism, and functionQ27861070
Switching from repression to activation: microRNAs can up-regulate translationQ28131790
MicroRNA signatures in human ovarian cancerQ28249211
Identification of hundreds of conserved and nonconserved human microRNAsQ28257480
Anatomical profiling of nuclear receptor expression reveals a hierarchical transcriptional networkQ28259101
Altered MicroRNA expression confined to specific epithelial cell subpopulations in breast cancerQ28261558
Phylogenetic shadowing and computational identification of human microRNA genesQ28302536
The widespread impact of mammalian MicroRNAs on mRNA repression and evolutionQ29547173
Genome-wide analysis of estrogen receptor binding sitesQ29614765
Characterization of microRNA expression profiles in normal human tissuesQ29615492
Animal MicroRNAs confer robustness to gene expression and have a significant impact on 3'UTR evolutionQ29616370
Estrogen receptors: how do they signal and what are their targetsQ29617958
Repression of protein synthesis by miRNAs: how many mechanisms?Q29620361
RNA interference in mammalian cells using siRNAs synthesized with T7 RNA polymeraseQ33858008
Aryl hydrocarbon receptor-mediated transcription: ligand-dependent recruitment of estrogen receptor alpha to 2,3,7,8-tetrachlorodibenzo-p-dioxin-responsive promotersQ33863016
Human estrogen receptor-alpha: regulation by synthesis, modification and degradation.Q34712217
miR-206 Expression is down-regulated in estrogen receptor alpha-positive human breast cancerQ34791023
Genomic profiling of microRNA and messenger RNA reveals deregulated microRNA expression in prostate cancerQ34803786
Endocrine-responsive breast cancer and strategies for combating resistanceQ35084786
Inhibiting the mitochondrial fission machinery does not prevent Bax/Bak-dependent apoptosis.Q35131723
Activation of the unliganded estrogen receptor by EGF involves the MAP kinase pathway and direct phosphorylationQ35849279
Steroid hormones regulate gene expression posttranscriptionally by altering the stabilities of messenger RNAsQ36053373
Dissociation of estrogen receptor expression and in vivo stem cell activity in the mammary glandQ36117022
A role for microRNAs in maintenance of mouse mammary epithelial progenitor cellsQ36209715
Epigenetic information and estrogen receptor alpha expression in breast cancerQ36364262
Extranuclear steroid receptors: nature and actionsQ36960789
Estrogen receptors in resistance to hormone therapy.Q36997404
Small is beautiful: microRNAs and breast cancer-where are we now?Q37151040
Proteasome-dependent degradation of the human estrogen receptorQ37160826
MicroRNA-18a prevents estrogen receptor-alpha expression, promoting proliferation of hepatocellular carcinoma cellsQ39913331
Curcumin (diferuloylmethane) alters the expression profiles of microRNAs in human pancreatic cancer cellsQ40001498
AU-rich-element-mediated upregulation of translation by FXR1 and Argonaute 2.Q40154871
Human MicroRNA targetsQ21563637
MicroRNA targeting specificity in mammals: determinants beyond seed pairingQ24607724
MicroRNAs: target recognition and regulatory functionsQ24609584
A mammalian microRNA expression atlas based on small RNA library sequencingQ24644709
MicroRNA-221/222 negatively regulates estrogen receptor alpha and is associated with tamoxifen resistance in breast cancerQ24645663
Widespread microRNA repression by Myc contributes to tumorigenesisQ24647067
MicroRNA-221/222 confers tamoxifen resistance in breast cancer by targeting p27Kip1Q24648241
miRBase: tools for microRNA genomicsQ24649872
MicroRNA-373 induces expression of genes with complementary promoter sequencesQ24652547
The impact of microRNAs on protein outputQ24653549
Optimized high-throughput microRNA expression profiling provides novel biomarker assessment of clinical prostate and breast cancer biopsiesQ27497347
Prediction of mammalian microRNA targetsQ27860498
Combinatorial microRNA target predictionsQ27860510
Unique microRNA molecular profiles in lung cancer diagnosis and prognosisQ27860631
MicroRNA gene expression deregulation in human breast cancerQ27860690
Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targetsQ27860792
P433issue13
P407language of work or nameEnglishQ1860
P921main subjectestrogenQ277954
cell biologyQ7141
P304page(s)3783-90
P577publication date2009-07-01
P1433published inMolecular and Cellular BiologyQ3319478
P1476titlemiR-22 inhibits estrogen signaling by directly targeting the estrogen receptor alpha mRNA
P478volume29

Reverse relations

cites work (P2860)
Q553120062'-Hydroxyflavanone effectively targets RLIP76-mediated drug transport and regulates critical signaling networks in breast cancer.
Q906746936-Formylindolo[3,2-b]carbazole (FICZ) Enhances The Expression of Tumor Suppressor miRNAs, miR-22, miR-515-5p, and miR-124-3p in MCF-7 Cells
Q42501988A crossroad of microRNAs and immediate early genes (IEGs) encoding oncogenic transcription factors in breast cancer
Q33634277A link between mir-100 and FRAP1/mTOR in clear cell ovarian cancer
Q39032003A novel p53/microRNA-22/Cyr61 axis in synovial cells regulates inflammation in rheumatoid arthritis
Q37056916Aberrant Expression of Breast Development-Related MicroRNAs, miR-22, miR-132, and miR-212, in Breast Tumor Tissues
Q38237045Additional stories of microRNAs.
Q34146968Altered microRNA regulation in Huntington's disease models
Q33533878An estrogen receptor alpha suppressor, microRNA-22, is downregulated in estrogen receptor alpha-positive human breast cancer cell lines and clinical samples.
Q34140013An inhibitory effect of miR-22 on cell migration and invasion in ovarian cancer
Q37958686BRACking news on triple-negative/basal-like breast cancers: how BRCA1 deficiency may result in the development of a selective tumor subtype
Q34623204Characterization and differential expression of microRNAs in the ovaries of pregnant and non-pregnant goats (Capra hircus).
Q57092198Circulating MicroRNA Markers for Pulmonary Hypertension in Supervised Exercise Intervention and Nightly Oxygen Intervention
Q43512235Circulating microRNA-22 correlates with microRNA-122 and represents viral replication and liver injury in patients with chronic hepatitis B.
Q34246016Circulating microRNAs involved in multiple sclerosis
Q38339549Control of EVI-1 oncogene expression in metastatic breast cancer cells through microRNA miR-22.
Q51442271Crosstalk between the vitamin D receptor (VDR) and miR-214 in regulating SuFu, a hedgehog pathway inhibitor in breast cancer cells.
Q36589361Derailed estrogen signaling and breast cancer: an authentic couple.
Q35135063Developmental microRNA expression profiling of murine embryonic orofacial tissue
Q22000752Downregulation of the tumor-suppressor miR-16 via progestin-mediated oncogenic signaling contributes to breast cancer development
Q37682209Dynamics of miRNA transcriptome during gonadal development of zebrafish.
Q34119028ERalpha-negative and triple negative breast cancer: molecular features and potential therapeutic approaches
Q54314330Effect of curcumin on miRNA expression in human Y79 retinoblastoma cells.
Q37539078Elevated MiR-222-3p promotes proliferation and invasion of endometrial carcinoma via targeting ERα.
Q37211627Endocrine resistance in breast cancer: Current status and a perspective on the roles of miRNAs (Review).
Q37962586Epigenetic modulation: a novel therapeutic target for overcoming hormonal therapy resistance
Q24621879Epigenetic regulation of miR-184 by MBD1 governs neural stem cell proliferation and differentiation
Q38012175Epigenetics of estrogen receptor-negative primary breast cancer
Q54974230Estradiol and the Development of the Cerebral Cortex: An Unexpected Role?
Q36661810Estrogen receptors and human disease: an update
Q34521846Expression of miRNAs in ovine fetal gonads: potential role in gonadal differentiation.
Q36838871Hierarchical paracrine interaction of breast cancer associated fibroblasts with cancer cells via hMAPK-microRNAs to drive ER-negative breast cancer phenotype
Q54963939Identification of cancer-related miRNA-lncRNA biomarkers using a basic miRNA-lncRNA network.
Q26782613Integrating genetics and epigenetics in breast cancer: biological insights, experimental, computational methods and therapeutic potential
Q28816965Integrative analysis of miRNA and gene expression reveals regulatory networks in tamoxifen-resistant breast cancer
Q28284772Let-7 family miRNAs regulate estrogen receptor alpha signaling in estrogen receptor positive breast cancer
Q38267349Light-regulated microRNAs
Q38186042Links between oestrogen receptor activation and proteolysis: relevance to hormone-regulated cancer therapy.
Q58718563Mechanisms for estrogen receptor expression in human cancer
Q33637461Meeting report: nuclear receptors: transcription factors and drug targets connecting basic research with translational medicine
Q28079075MiRNAs and miRNA Polymorphisms Modify Drug Response
Q35625498MicroRNA Expression Profile in Bovine Granulosa Cells of Preovulatory Dominant and Subordinate Follicles during the Late Follicular Phase of the Estrous Cycle.
Q61999299MicroRNA Expression Profiling and Its Clinical Impact in Breast Cancer
Q36618667MicroRNA Pharmacoepigenetics: Posttranscriptional Regulation Mechanisms behind Variable Drug Disposition and Strategy to Develop More Effective Therapy
Q60421653MicroRNA Regulation of Endocrine Functions in the Ovary
Q41885247MicroRNA Regulatory Networks Provide Feedback Mechanisms for Steroid Receptor Signaling
Q54944098MicroRNA and Breast Cancer: Understanding Pathogenesis, Improving Management.
Q35811140MicroRNA expression profiles of bovine milk exosomes in response to Staphylococcus aureus infection
Q39535231MicroRNA miR-335 is crucial for the BRCA1 regulatory cascade in breast cancer development
Q50989062MicroRNA profiling in migraine without aura: pilot study.
Q33721789MicroRNA-101-mediated Akt activation and estrogen-independent growth
Q41136545MicroRNA-135b regulates ERα, AR and HIF1AN and affects breast and prostate cancer cell growth
Q37111953MicroRNA-22 and promoter motif polymorphisms at the Chga locus in genetic hypertension: functional and therapeutic implications for gene expression and the pathogenesis of hypertension.
Q34228326MicroRNA-22 can reduce parathymosin expression in transdifferentiated hepatocytes
Q43693182MicroRNA-22 expression in hepatocellular carcinoma and its correlation with ezrin protein
Q38638014MicroRNA-22 inhibits cell growth and metastasis in breast cancer via targeting of SIRT1.
Q40434551MicroRNA-22 promotes cell survival upon UV radiation by repressing PTEN.
Q37038566MicroRNA-22 regulates cardiac hypertrophy and remodeling in response to stress
Q33918344MicroRNA-22 regulates hypoxia signaling in colon cancer cells
Q47073092MicroRNA-22 regulates inflammation and angiogenesis via targeting VE-cadherin
Q30414321MicroRNA-608 and microRNA-34a regulate chordoma malignancy by targeting EGFR, Bcl-xL and MET.
Q37156452MicroRNA-antagonism regulates breast cancer stemness and metastasis via TET-family-dependent chromatin remodeling.
Q37941371MicroRNA-mediated breast cancer metastasis: from primary site to distant organs
Q38235604MicroRNAs as key regulators of xenobiotic biotransformation and drug response.
Q36032709MicroRNAs link estrogen receptor alpha status and Dicer levels in breast cancer
Q37755682Modulation of steroid hormone receptor activity
Q37588086Molecular mechanisms and clinical applications of miR-22 in regulating malignant progression in human cancer (Review).
Q41660975Myeloperoxidase oxidized LDL interferes with endothelial cell motility through miR-22 and heme oxygenase 1 induction: possible involvement in reendothelialization of vascular injuries
Q89597721Non-Coding RNAs as Regulators and Markers for Targeting of Breast Cancer and Cancer Stem Cells
Q37605740Novel blood-based microRNA biomarker panel for early diagnosis of pancreatic cancer
Q37835900Nuclear receptors and microRNAs: Who regulates the regulators in neural stem cells?
Q37529397Oestrogen receptor negativity in breast cancer: a cause or consequence?
Q42755954Overcoming Resistance to Endocrine Therapy in Breast Cancer: New Approaches to a Nagging Problem
Q37878207Pharmocoepigenetics: a new approach to predicting individual drug responses and targeting new drugs
Q39011089Prediction of treatment response to adalimumab: a double-blind placebo-controlled study of circulating microRNA in patients with early rheumatoid arthritis.
Q33721926Proteasome inhibition represses ERalpha gene expression in ER+ cells: a new link between proteasome activity and estrogen signaling in breast cancer
Q37802877Proteomics of osteoarthritic chondrocytes and cartilage
Q48297415Role of MicroRNA Regulation in Obesity-Associated Breast Cancer: Nutritional Perspectives
Q26778413Role of Sex Hormones in the Development and Progression of Hepatitis B Virus-Associated Hepatocellular Carcinoma
Q37710885Role of estrogen in hepatocellular carcinoma: is inflammation the key?
Q36677690Role of microRNAs in breast cancer
Q37995667Role of microRNAs in the regulation of drug metabolizing and transporting genes and the response to environmental toxicants
Q54918383Serum miR-22 as potential non-invasive predictor of poor clinical outcome in newly diagnosed, uniformly treated patients with diffuse large B-cell lymphoma: an explorative pilot study.
Q48044643Sex-specific, reciprocal regulation of ERα and miR-22 controls muscle lipid metabolism in male mice
Q37811192Steroid receptors and microRNAs: Relationships revealed
Q38827031Systematic integration of molecular profiles identifies miR-22 as a regulator of lipid and folate metabolism in breast cancer cells
Q36562356TIP60-miR-22 axis as a prognostic marker of breast cancer progression
Q27003230Targeting CSC-related miRNAs for cancer therapy by natural agents
Q26830734The Akt-associated microRNAs
Q37210542The biological kinship of hypoxia with CSC and EMT and their relationship with deregulated expression of miRNAs and tumor aggressiveness.
Q37903655The different roles of ER subtypes in cancer biology and therapy
Q26822987The effects of microRNA on the absorption, distribution, metabolism and excretion of drugs
Q37354147The estrogen receptor-alpha-induced microRNA signature regulates itself and its transcriptional response.
Q36367578The impact of microRNA expression on cellular proliferation
Q42324249The inhibition role of miR-22 in hepatocellular carcinoma cell migration and invasion via targeting CD147.
Q34408630The many faces of estrogen signaling.
Q38381678The novel role of miRNAs for tamoxifen resistance in human breast cancer
Q41098508The zinc-finger transcriptional factor Slug transcriptionally downregulates ERα by recruiting lysine-specific demethylase 1 in human breast cancer
Q37895810Toxicological implications of modulation of gene expression by microRNAs.
Q44608082Tumor suppressor miR-22 determines p53-dependent cellular fate through post-transcriptional regulation of p21.
Q39367785Tumor suppressor miR-22 suppresses lung cancer cell progression through post-transcriptional regulation of ErbB3.
Q35746187Uterine microRNA signature and consequence of their dysregulation in uterine disorders.
Q34117084Variation among rainbow trout (Oncorhynchus mykiss) estrogen receptor isoform 3' untranslated regions and the effect of 17beta-estradiol on mRNA stability in hepatocyte culture
Q48096559Whole blood microRNAs as potential biomarkers in post-operative early breast cancer patients
Q34517731miR-22 controls Irf8 mRNA abundance and murine dendritic cell development
Q21091130miR-22 forms a regulatory loop in PTEN/AKT pathway and modulates signaling kinetics
Q34225020miR-22 in cardiac remodeling and disease
Q39006097miR-22 inhibits proliferation and invasion in estrogen receptor α-positive endometrial endometrioid carcinomas cells
Q37536852miR-22 inhibits tumor growth and metastasis by targeting ATP citrate lyase: evidence in osteosarcoma, prostate cancer, cervical cancer and lung cancer
Q34825182miR-22 represses cancer progression by inducing cellular senescence
Q36603816miR-342 is associated with estrogen receptor-α expression and response to tamoxifen in breast cancer
Q38905249miR-491-5p functions as a tumor suppressor by targeting JMJD2B in ERα-positive breast cancer
Q36902949miRNA expression profiling of 51 human breast cancer cell lines reveals subtype and driver mutation-specific miRNAs
Q35946984miRNAs and estrogen action
Q35912303miRNAs regulated by estrogens, tamoxifen, and endocrine disruptors and their downstream gene targets.
Q57106025microRNA Regulation in Estrogen Receptor-Positive Breast Cancer and Endocrine Therapy
Q33954625microRNA and cancer
Q38827929microRNA profiling in atherosclerosis, diabetes, and migraine.
Q24620203microRNA-22, downregulated in hepatocellular carcinoma and correlated with prognosis, suppresses cell proliferation and tumourigenicity
Q37760459microRNAs and EMT in mammary cells and breast cancer.
Q38336073microRNAs in breast cancer: regulatory roles governing the hallmarks of cancer
Q37246198microRNAs in liver disease: from diagnostics to therapeutics

Search more.