scholarly article | Q13442814 |
P50 | author | Renato V. Iozzo | Q37371755 |
John Whitelock | Q72877139 | ||
P2093 | author name string | Shiu-Ying Ho | |
Angela McQuillan | |||
Jason J Zoeller | |||
P2860 | cites work | p53 activation by knockdown technologies | Q21563456 |
Heparan sulfate chains of perlecan are indispensable in the lens capsule but not in the kidney | Q24540314 | ||
Antisense targeting of perlecan blocks tumor growth and angiogenesis in vivo | Q24564477 | ||
Suppression of autocrine and paracrine functions of basic fibroblast growth factor by stable expression of perlecan antisense cDNA | Q24646731 | ||
Perlecan maintains the integrity of cartilage and some basement membranes | Q24680954 | ||
Perlecan is essential for cartilage and cephalic development | Q28146148 | ||
Role of perlecan in skeletal development and diseases | Q28207258 | ||
Endorepellin, a novel inhibitor of angiogenesis derived from the C terminus of perlecan | Q28215134 | ||
A role for perlecan in the suppression of growth and invasion in fibrosarcoma cells | Q28241050 | ||
Developmental expression of perlecan during murine embryogenesis | Q28251854 | ||
Impaired angiogenesis, delayed wound healing and retarded tumor growth in perlecan heparan sulfate-deficient mice | Q28272282 | ||
Matrix proteoglycans: from molecular design to cellular function | Q28284300 | ||
BMP-1/Tolloid-like metalloproteases process endorepellin, the angiostatic C-terminal fragment of perlecan | Q28297745 | ||
Hedgehog signaling is essential for endothelial tube formation during vasculogenesis | Q28587747 | ||
Absence of acetylcholinesterase at the neuromuscular junctions of perlecan-null mice | Q28588415 | ||
Effective targeted gene 'knockdown' in zebrafish | Q29547445 | ||
Angiogenesis in life, disease and medicine | Q29614539 | ||
Heparan sulphate proteoglycans fine-tune mammalian physiology | Q29619329 | ||
In vivo imaging of embryonic vascular development using transgenic zebrafish | Q29619921 | ||
Patterning of angiogenesis in the zebrafish embryo | Q31039755 | ||
Systematic Analysis of proteoglycan modification sites in Caenorhabditis elegans by scanning mutagenesis | Q33279266 | ||
Disruption of perlecan binding and matrix assembly by post-translational or genetic disruption of dystroglycan function | Q33289428 | ||
The Drosophila Perlecan gene trol regulates multiple signaling pathways in different developmental contexts | Q33304884 | ||
Notch signaling is required for arterial-venous differentiation during embryonic vascular development. | Q34093638 | ||
Heparan sulfate proteoglycans: heavy hitters in the angiogenesis arena | Q34328750 | ||
Hedgehog signaling is required for adult blood stem cell formation in zebrafish embryos | Q34398804 | ||
Basement membrane proteoglycans: from cellar to ceiling | Q34439478 | ||
Perlecan, a candidate gene for the CAPB locus, regulates prostate cancer cell growth via the Sonic Hedgehog pathway | Q34499215 | ||
Distinct genetic interactions between multiple Vegf receptors are required for development of different blood vessel types in zebrafish | Q34597815 | ||
The zebrafish as a model for muscular dystrophy and congenital myopathy | Q35540869 | ||
Expression and localization of acetylcholinesterase at the neuromuscular junction | Q35700819 | ||
Endorepellin, the C-terminal angiostatic module of perlecan, enhances collagen-platelet responses via the alpha2beta1-integrin receptor | Q35804438 | ||
Heparan sulfate: a complex polymer charged with biological activity | Q36190979 | ||
Acetylcholinesterase clustering at the neuromuscular junction involves perlecan and dystroglycan | Q36256611 | ||
Endorepellin causes endothelial cell disassembly of actin cytoskeleton and focal adhesions through alpha2beta1 integrin. | Q36322054 | ||
Diagnosis and cell-based therapy for Duchenne muscular dystrophy in humans, mice, and zebrafish | Q36438833 | ||
Perlecan signaling: helping hedgehog stimulate prostate cancer growth | Q36496152 | ||
Proteomic profiling of endorepellin angiostatic activity on human endothelial cells | Q36509450 | ||
Modeling human muscle disease in zebrafish | Q36578338 | ||
Perlecan: how does one molecule do so many things? | Q36585177 | ||
Distinct requirements for zebrafish angiogenesis revealed by a VEGF-A morphant | Q36750445 | ||
Perlecan and Dystroglycan act at the basal side of the Drosophila follicular epithelium to maintain epithelial organization | Q37366097 | ||
Integrin alpha2beta1 is the required receptor for endorepellin angiostatic activity | Q40048806 | ||
Endorepellin in vivo: targeting the tumor vasculature and retarding cancer growth and metabolism | Q40208428 | ||
Isolation and purification of proteoglycans. | Q40724158 | ||
The vascular anatomy of the developing zebrafish: an atlas of embryonic and early larval development | Q40728953 | ||
Interaction of skeletal muscle cells with collagen type IV is mediated by perlecan associated with the cell surface | Q40916274 | ||
Human perlecan immunopurified from different endothelial cell sources has different adhesive properties for vascular cells. | Q40947660 | ||
The relationship between perlecan and dystroglycan and its implication in the formation of the neuromuscular junction. | Q40999408 | ||
Perlecan heparan sulfate proteoglycan: a novel receptor that mediates a distinct pathway for ligand catabolism | Q41921681 | ||
Binding of the G domains of laminin alpha1 and alpha2 chains and perlecan to heparin, sulfatides, alpha-dystroglycan and several extracellular matrix proteins | Q42001102 | ||
Perlecan, basal lamina proteoglycan, promotes basic fibroblast growth factor-receptor binding, mitogenesis, and angiogenesis | Q42476789 | ||
Limits to the development of fast neuromuscular transmission in zebrafish. | Q42513644 | ||
Hyperplastic conotruncal endocardial cushions and transposition of great arteries in perlecan-null mice. | Q42524186 | ||
Reduced perlecan in mice results in chondrodysplasia resembling Schwartz-Jampel syndrome | Q42832135 | ||
Acetylcholinesterase is required for neuronal and muscular development in the zebrafish embryo | Q43830797 | ||
Conjugation of LG domains of agrins and perlecan to polymerizing laminin-2 promotes acetylcholine receptor clustering | Q46748108 | ||
Dystrophin is required for the formation of stable muscle attachments in the zebrafish embryo | Q47073103 | ||
Removal of dystroglycan causes severe muscular dystrophy in zebrafish embryos. | Q47073130 | ||
Genes controlling and mediating locomotion behavior of the zebrafish embryo and larva. | Q47073234 | ||
sonic hedgehog and vascular endothelial growth factor act upstream of the Notch pathway during arterial endothelial differentiation | Q47074043 | ||
Delta-sarcoglycan is required for early zebrafish muscle organization | Q47074188 | ||
Drosophila perlecan modulates FGF and hedgehog signals to activate neural stem cell division | Q48360653 | ||
Spectrum ofHSPG2(Perlecan) mutations in patients with Schwartz-Jampel syndrome | Q57639997 | ||
Rapid analysis of angiogenesis drugs in a live fluorescent zebrafish assay | Q73376523 | ||
Development of the coronary arteries in a murine model of transposition of great arteries | Q73556346 | ||
Angiogenic network formation in the developing vertebrate trunk | Q73898704 | ||
Increased intimal hyperplasia and smooth muscle cell proliferation in transgenic mice with heparan sulfate-deficient perlecan | Q75318637 | ||
P433 | issue | 2 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | cell biology | Q7141 |
circulatory system | Q11068 | ||
P304 | page(s) | 381-394 | |
P577 | publication date | 2008-04-01 | |
P1433 | published in | Journal of Cell Biology | Q1524550 |
P1476 | title | A central function for perlecan in skeletal muscle and cardiovascular development | |
P478 | volume | 181 |
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Q30392738 | A current view of perlecan in physiology and pathology: A mosaic of functions |
Q30489730 | A key role for the integrin alpha2beta1 in experimental and developmental angiogenesis. |
Q42156659 | Abnormal retinal development in Cloche mutant zebrafish |
Q49490232 | Are mechanically sensitive regulators involved in the function and (patho)physiology of cerebral palsy-related contractures? |
Q41570390 | At the Start of the Sarcomere: A Previously Unrecognized Role for Myosin Chaperones and Associated Proteins during Early Myofibrillogenesis |
Q37739297 | Basement membrane components are key players in specialized extracellular matrices |
Q37494563 | Basement membrane proteoglycans: modulators Par Excellence of cancer growth and angiogenesis. |
Q46222214 | Betaglycan knock-down causes embryonic angiogenesis defects in zebrafish |
Q34304413 | Blood vessel repair and regeneration in the ischaemic heart |
Q34512935 | Collagen type IV and Perlecan exhibit dynamic localization in the Allantoic Core Domain, a putative stem cell niche in the murine allantois |
Q26801397 | Decoding the Matrix: Instructive Roles of Proteoglycan Receptors |
Q34439113 | Decorin antagonizes Met receptor activity and down-regulates {beta}-catenin and Myc levels |
Q35773980 | Decorin antagonizes the angiogenic network: concurrent inhibition of Met, hypoxia inducible factor 1α, vascular endothelial growth factor A, and induction of thrombospondin-1 and TIMP3. |
Q37020797 | Diverse cell signaling events modulated by perlecan. |
Q30497859 | Embryonic mouse blood flow and oxygen correlate with early pancreatic differentiation |
Q36481790 | Endorepellin affects angiogenesis by antagonizing diverse vascular endothelial growth factor receptor 2 (VEGFR2)-evoked signaling pathways: transcriptional repression of hypoxia-inducible factor 1α and VEGFA and concurrent inhibition of nuclear fact |
Q90604542 | Endorepellin evokes an angiostatic stress signaling cascade in endothelial cells |
Q33718473 | Endorepellin evokes autophagy in endothelial cells |
Q24312922 | Endorepellin laminin-like globular 1/2 domains bind Ig3-5 of vascular endothelial growth factor (VEGF) receptor 2 and block pro-angiogenic signaling by VEGFA in endothelial cells |
Q24303934 | Endorepellin, the angiostatic module of perlecan, interacts with both the α2β1 integrin and vascular endothelial growth factor receptor 2 (VEGFR2): a dual receptor antagonism |
Q41049426 | Endorepellin-evoked Autophagy Contributes to Angiostasis. |
Q36578668 | Endostatin and endorepellin: A common route of action for similar angiostatic cancer avengers |
Q37488302 | EphA2 is a functional receptor for the growth factor progranulin. |
Q38423857 | Extracellular matrix communication and turnover in cardiac physiology and pathology |
Q37354921 | Force measurement during contraction to assess muscle function in zebrafish larvae. |
Q28087402 | Hanging on for the ride: adhesion to the extracellular matrix mediates cellular responses in skeletal muscle morphogenesis and disease |
Q37071520 | In vitro and in vivo characterization of the anticancer activity of Thai stingless bee (Tetragonula laeviceps) cerumen |
Q96230847 | Is HSPG2 a modifier gene for Marfan syndrome? |
Q36531788 | Laminin-211 in skeletal muscle function |
Q30496686 | Mtmr8 is essential for vasculature development in zebrafish embryos. |
Q33735983 | NGS nominated CELA1, HSPG2, and KCNK5 as candidate genes for predisposition to Balkan endemic nephropathy |
Q34126666 | Perlecan deficiency causes muscle hypertrophy, a decrease in myostatin expression, and changes in muscle fiber composition |
Q34548326 | Perlecan maintains microvessel integrity in vivo and modulates their formation in vitro |
Q24653433 | Perlecan regulates developmental angiogenesis by modulating the VEGF-VEGFR2 axis. |
Q55280437 | Perlecan, a heparan sulfate proteoglycan, regulates systemic metabolism with dynamic changes in adipose tissue and skeletal muscle. |
Q92881075 | Production of Extracellular Matrix Proteins in the Cytoplasm of E. coli: Making Giants in Tiny Factories |
Q21710680 | Proteoglycan form and function: A comprehensive nomenclature of proteoglycans |
Q36787608 | Proteoglycans in cancer biology, tumour microenvironment and angiogenesis |
Q36884215 | Proteoglycans regulate autophagy via outside-in signaling: an emerging new concept |
Q35806361 | Reverse genetic screening reveals poor correlation between morpholino-induced and mutant phenotypes in zebrafish. |
Q37458773 | Soft texture of atlantic salmon fillets is associated with glycogen accumulation |
Q91606840 | Temporal characterization of optic fissure basement membrane composition suggests nidogen may be an initial target of remodeling |
Q30540461 | The Popeye domain containing 2 (popdc2) gene in zebrafish is required for heart and skeletal muscle development |
Q38281725 | The cardiovascular triad of dysfunctional angiogenesis. |
Q39063783 | The nature and biology of basement membranes |
Q34783479 | The proteoglycan Trol controls the architecture of the extracellular matrix and balances proliferation and differentiation of blood progenitors in the Drosophila lymph gland |
Q36542074 | The role of extracellular matrix in vascular branching morphogenesis |
Q26800258 | The role of perlecan and endorepellin in the control of tumor angiogenesis and endothelial cell autophagy |
Q37271260 | The role of vascular-derived perlecan in modulating cell adhesion, proliferation and growth factor signaling. |
Q103837757 | Two different sources of Perlecan cooperate for its function in the basement membrane of the Drosophila wing imaginal disc |
Q38172265 | Urinary biomarkers of physical activity: candidates and clinical utility. |
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