scholarly article | Q13442814 |
P2093 | author name string | D M Noonan | |
R V Iozzo | |||
A Yayon | |||
D Aviezer | |||
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Abnormal expression of perlecan proteoglycan in metastatic melanomas | Q28240180 | ||
The degradation of human endothelial cell-derived perlecan and release of bound basic fibroblast growth factor by stromelysin, collagenase, plasmin, and heparanases | Q28278296 | ||
Requirement of heparan sulfate for bFGF-mediated fibroblast growth and myoblast differentiation | Q28296150 | ||
Formation of heparan sulfate or chondroitin/dermatan sulfate on recombinant domain I of mouse perlecan expressed in Chinese hamster ovary cells | Q28303061 | ||
Characterization of the murine BEK fibroblast growth factor (FGF) receptor: activation by three members of the FGF family and requirement for heparin | Q28316159 | ||
Cell surface, heparin-like molecules are required for binding of basic fibroblast growth factor to its high affinity receptor | Q29616189 | ||
The complete sequence of perlecan, a basement membrane heparan sulfate proteoglycan, reveals extensive similarity with laminin A chain, low density lipoprotein-receptor, and the neural cell adhesion molecule | Q34620069 | ||
A human beta-actin expression vector system directs high-level accumulation of antisense transcripts | Q34638492 | ||
Control of Angiogenesis by Heparin and Other Sulfated Polysaccharides | Q35150877 | ||
The FGF family of growth factors and oncogenes | Q35335377 | ||
Distribution and origin of the basement membrane component perlecan in rat liver and primary hepatocyte culture | Q35832611 | ||
Biosynthesis of heparan sulfate proteoglycan by human colon carcinoma cells and its localization at the cell surface | Q36210792 | ||
Autocrine regulation of cell growth and transformation by basic fibroblast growth factor | Q38037837 | ||
The fibroblast growth factor family: structural and biological properties | Q38218868 | ||
Receptor binding and mitogenic properties of mouse fibroblast growth factor 3. Modulation of response by heparin | Q38290375 | ||
Structural requirements in heparin for binding and activation of FGF-1 and FGF-4 are different from that for FGF-2. | Q38302156 | ||
Specific heparan sulfate saccharides mediate the activity of basic fibroblast growth factor. | Q38312077 | ||
Differential structural requirements of heparin and heparan sulfate proteoglycans that promote binding of basic fibroblast growth factor to its receptor | Q38312264 | ||
Inhibition of basic fibroblast growth factor-induced growth promotion by overexpression of syndecan-1. | Q38314271 | ||
Minimal sequence in heparin/heparan sulfate required for binding of basic fibroblast growth factor | Q38314305 | ||
Activating and inhibitory heparin sequences for FGF-2 (basic FGF). Distinct requirements for FGF-1, FGF-2, and FGF-4 | Q38314349 | ||
Heparin is required for cell-free binding of basic fibroblast growth factor to a soluble receptor and for mitogenesis in whole cells | Q38331586 | ||
Heparan sulphates as membrane receptors for the fibroblast growth factors. | Q40675786 | ||
Proliferation of human malignant melanomas is inhibited by antisense oligodeoxynucleotides targeted against basic fibroblast growth factor | Q40822228 | ||
Heparan sulfates mediate the binding of basic fibroblast growth factor to a specific receptor on neural precursor cells | Q41281609 | ||
Recombinant domain III of perlecan promotes cell attachment through its RGDS sequence | Q41381551 | ||
Regulation by heparan sulfate in fibroblast growth factor signaling | Q41505290 | ||
Transformation of murine melanocytes by basic fibroblast growth factor cDNA and oncogenes and selective suppression of the transformed phenotype in a reconstituted cutaneous environment | Q41760172 | ||
The biology of perlecan: the multifaceted heparan sulphate proteoglycan of basement membranes and pericellular matrices | Q42248769 | ||
Perlecan, basal lamina proteoglycan, promotes basic fibroblast growth factor-receptor binding, mitogenesis, and angiogenesis | Q42476789 | ||
Requirement for heparan sulphate proteoglycans to mediate basic fibroblast growth factor (FGF-2)-induced stimulation of Leydig cell steroidogenesis. | Q42479092 | ||
Myoepithelial and basement membrane antigens in benign and malignant human breast tumors | Q42509695 | ||
Primary structure of the human heparan sulfate proteoglycan from basement membrane (HSPG2/perlecan). A chimeric molecule with multiple domains homologous to the low density lipoprotein receptor, laminin, neural cell adhesion molecules, and epidermal | Q42610425 | ||
Developmental Regulation of Neural Response to FGF-1 and FGF-2 by Heparan Sulfate Proteoglycan | Q52225676 | ||
Heparin-induced oligomerization of FGF molecules is responsible for FGF receptor dimerization, activation, and cell proliferation | Q54246457 | ||
bFGF as an autocrine growth factor for human melanomas | Q56428502 | ||
In vitro changes in plasma membrane heparan sulfate proteoglycans and in perlecan expression participate in the regulation of fibroblast growth factor 2 mitogenic activity | Q70890126 | ||
Multivalent Ligand-Receptor Binding Interactions in the Fibroblast Growth Factor System Produce a Cooperative Growth Factor and Heparin Mechanism for Receptor Dimerization | Q71642294 | ||
KIT ligand (mast cell growth factor) inhibits the growth of KIT-expressing melanoma cells | Q72088611 | ||
Potential markers (enzymes, proteoglycans) for human liver tumors | Q72888162 | ||
P433 | issue | 4 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 1938-46 | |
P577 | publication date | 1997-04-01 | |
P1433 | published in | Molecular and Cellular Biology | Q3319478 |
P1476 | title | Suppression of autocrine and paracrine functions of basic fibroblast growth factor by stable expression of perlecan antisense cDNA | |
P478 | volume | 17 |
Q24648227 | A central function for perlecan in skeletal muscle and cardiovascular development |
Q33292070 | A novel interaction between perlecan protein core and progranulin: potential effects on tumor growth |
Q41895425 | A role for the perlecan protein core in the activation of the keratinocyte growth factor receptor |
Q24564477 | Antisense targeting of perlecan blocks tumor growth and angiogenesis in vivo |
Q37941513 | Antithetic roles of proteoglycans in cancer. |
Q37494563 | Basement membrane proteoglycans: modulators Par Excellence of cancer growth and angiogenesis. |
Q48205871 | Basic fibroblast growth factor in the primary olfactory pathway: mitogenic effect on ensheathing cells |
Q36802889 | Bladder defense molecules, urothelial differentiation, urinary biomarkers, and interstitial cystitis |
Q35768716 | Brain metastases in melanoma: roles of neurotrophins |
Q35552852 | Brain-metastatic melanoma: a neurotrophic perspective |
Q52375995 | Cell surface chondroitin sulphate proteoglycan 4 (CSPG4) binds to the basement membrane heparan sulphate proteoglycan, perlecan, and is involved in cell adhesion. |
Q28251854 | Developmental expression of perlecan during murine embryogenesis |
Q92965276 | Discovery of HSPG2 (Perlecan) as a Therapeutic Target in Triple Negative Breast Cancer |
Q36481790 | Endorepellin affects angiogenesis by antagonizing diverse vascular endothelial growth factor receptor 2 (VEGFR2)-evoked signaling pathways: transcriptional repression of hypoxia-inducible factor 1α and VEGFA and concurrent inhibition of nuclear fact |
Q33718473 | Endorepellin evokes autophagy in endothelial cells |
Q24312922 | Endorepellin laminin-like globular 1/2 domains bind Ig3-5 of vascular endothelial growth factor (VEGF) receptor 2 and block pro-angiogenic signaling by VEGFA in endothelial cells |
Q24303934 | Endorepellin, the angiostatic module of perlecan, interacts with both the α2β1 integrin and vascular endothelial growth factor receptor 2 (VEGFR2): a dual receptor antagonism |
Q36578668 | Endostatin and endorepellin: A common route of action for similar angiostatic cancer avengers |
Q39005090 | Epac1 increases migration of endothelial cells and melanoma cells via FGF2-mediated paracrine signaling |
Q28142123 | Fibroblast growth factor-binding protein is a novel partner for perlecan protein core |
Q28283514 | Fibroblast growth factors as multifunctional signaling factors |
Q34033148 | From the outside in: extracellular activities of HIV Tat. |
Q37728933 | Functional genomics of endothelial cells treated with anti-angiogenic or angiopreventive drugs |
Q34441253 | Heparan sulfate proteoglycans and cancer. |
Q34328750 | Heparan sulfate proteoglycans: heavy hitters in the angiogenesis arena |
Q38418286 | Heparin/Heparan sulfate proteoglycans glycomic interactome in angiogenesis: biological implications and therapeutical use. |
Q47878776 | Inhibition of DNA topoisomerase I activity by heparan sulfate and modulation by basic fibroblast growth factor. |
Q40048806 | Integrin alpha2beta1 is the required receptor for endorepellin angiostatic activity |
Q40916274 | Interaction of skeletal muscle cells with collagen type IV is mediated by perlecan associated with the cell surface |
Q48685507 | Intracellular trafficking in neurones and glia of fibroblast growth factor-2, fibroblast growth factor receptor 1 and heparan sulphate proteoglycans in the injured adult rat cerebral cortex |
Q37094730 | Novel interactions of perlecan: unraveling perlecan's role in angiogenesis. |
Q35562693 | Perlecan and tumor angiogenesis |
Q39078431 | Perlecan domain I promotes fibroblast growth factor 2 delivery in collagen I fibril scaffolds. |
Q52945127 | Perlecan heparan sulfate deficiency impairs pulmonary vascular development and attenuates hypoxic pulmonary hypertension. |
Q28146148 | Perlecan is essential for cartilage and cephalic development |
Q54069183 | Perlecan mediates the antiproliferative effect of apolipoprotein E on smooth muscle cells. An underlying mechanism for the modulation of smooth muscle cell growth? |
Q24653433 | Perlecan regulates developmental angiogenesis by modulating the VEGF-VEGFR2 axis. |
Q28140820 | Phenotypic alterations in Kaposi's sarcoma cells by antisense reduction of perlecan |
Q21710680 | Proteoglycan form and function: A comprehensive nomenclature of proteoglycans |
Q34706643 | Proteoglycans and tumor progression: Janus-faced molecules with contradictory functions in cancer. |
Q36787608 | Proteoglycans in cancer biology, tumour microenvironment and angiogenesis |
Q37636855 | Proteoglycans: master modulators of paracrine fibroblast-carcinoma cell interactions |
Q36509450 | Proteomic profiling of endorepellin angiostatic activity on human endothelial cells |
Q58058008 | Recruitment of a Heparan Sulfate Subunit to the Interleukin-1 Receptor Complex |
Q28245112 | Spatial and temporal expression of perlecan in the early chick embryo |
Q45885892 | Suppression of invasive behavior of melanoma cells by stable expression of anti-sense perlecan cDNA. |
Q31971336 | Syndecan-1 expression inhibits myoblast differentiation through a basic fibroblast growth factor-dependent mechanism. |
Q30850721 | Syndecan-2 is involved in the mitogenic activity and signaling of granulocyte-macrophage colony-stimulating factor in osteoblasts. |
Q38319148 | Targeting perlecan in human keratinocytes reveals novel roles for perlecan in epidermal formation |
Q33304884 | The Drosophila Perlecan gene trol regulates multiple signaling pathways in different developmental contexts |
Q33361929 | The Extracellular Matrix in Epithelial Ovarian Cancer - A Piece of a Puzzle |
Q28145823 | The protein core of the proteoglycan perlecan binds specifically to fibroblast growth factor-7 |
Q36376753 | The role of heparan sulfate and perlecan in bone-regenerative procedures |
Q26800258 | The role of perlecan and endorepellin in the control of tumor angiogenesis and endothelial cell autophagy |
Q37289299 | The role of the biochemical and biophysical environment in chondrogenic stem cell differentiation assays and cartilage tissue engineering |
Q37271260 | The role of vascular-derived perlecan in modulating cell adhesion, proliferation and growth factor signaling. |
Q28262244 | Transcriptional silencing of perlecan gene expression by interferon-gamma |
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