Targeting perlecan in human keratinocytes reveals novel roles for perlecan in epidermal formation

scientific article

Targeting perlecan in human keratinocytes reveals novel roles for perlecan in epidermal formation is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M509500200
P698PubMed publication ID16269412
P5875ResearchGate publication ID7499513

P50authorRenato V. IozzoQ37371755
Reuven BergmanQ117264463
P2093author name stringDina Ron
Ifat Sher
Eri Arikawa-Hirasawa
Yoshihiko Yamada
Simona Zisman-Rozen
Dirk Breitkreutz
John M Whitelock
Nicole Maas-Szabowski
Norbert E Fusenig
Liat Eliahu
P2860cites workInhibition of basement membrane formation by a nidogen-binding laminin gamma1-chain fragment in human skin-organotypic coculturesQ24294215
Human KGF is FGF-related with properties of a paracrine effector of epithelial cell growthQ24295049
Heparan sulfate chains of perlecan are indispensable in the lens capsule but not in the kidneyQ24540314
Antisense targeting of perlecan blocks tumor growth and angiogenesis in vivoQ24564477
Suppression of autocrine and paracrine functions of basic fibroblast growth factor by stable expression of perlecan antisense cDNAQ24646731
Perlecan maintains the integrity of cartilage and some basement membranesQ24680954
Fibroblast growth factors, their receptors and signalingQ28140520
Organotypic keratinocyte cocultures in defined medium with regular epidermal morphogenesis and differentiationQ28143290
The Ki-67 protein: from the known and the unknownQ28143714
The protein core of the proteoglycan perlecan binds specifically to fibroblast growth factor-7Q28145823
Perlecan is essential for cartilage and cephalic developmentQ28146148
The C‐Terminal Domain V of Perlecan Promotes β1 Integrin‐Mediated Cell Adhesion, Binds Heparin, Nidogen and Fibulin‐2 and Can be Modified by GlycosaminoglycansQ28259215
Impaired angiogenesis, delayed wound healing and retarded tumor growth in perlecan heparan sulfate-deficient miceQ28272282
The N‐terminal globular domain of the laminin α1 chain binds to α1β1 and α2β1 integrins and to the heparan sulfate‐containing domains of perlecanQ28278214
Keratinocyte growth factor/fibroblast growth factor 7, a homeostatic factor with therapeutic potential for epithelial protection and repairQ28278567
Alternative splicing generates an isoform of the human Sef gene with altered subcellular localization and specificityQ28312213
Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell lineQ29547520
Serial cultivation of strains of human epidermal keratinocytes: the formation of keratinizing colonies from single cellsQ29614425
Functions of cell surface heparan sulfate proteoglycansQ29618521
Heparan sulfate: lessons from knockout miceQ30689506
Epidermal cell lineageQ33678380
Life without perlecan has its problemsQ33783384
FGFs, heparan sulfate and FGFRs: complex interactions essential for developmentQ33828280
Carcinogenesis in mouse and human cells: parallels and paradoxesQ33846175
Epidermal differentiation, apoptosis, and senescence: common pathways?Q33855465
Cellular functions of proteoglycans--an overview.Q34211741
Nrf2 transcription factor, a novel target of keratinocyte growth factor action which regulates gene expression and inflammation in the healing skin woundQ34283835
Heparan sulfate proteoglycans: intricate molecules with intriguing functions.Q34310368
Heparan sulfate proteoglycans: heavy hitters in the angiogenesis arenaQ34328750
Extracellular matrix and keratinocyte migration.Q34419124
Heparan sulfate proteoglycans and cancer.Q34441253
Science, medicine and the future: healing chronic woundsQ34499583
Role of integrins in regulating epidermal adhesion, growth and differentiationQ34764924
Perlecan and tumor angiogenesisQ35562693
Perlecan is required to inhibit thrombosis after deep vascular injury and contributes to endothelial cell-mediated inhibition of intimal hyperplasiaQ35799754
Endothelial cell-derived heparan sulfate binds basic fibroblast growth factor and protects it from proteolytic degradationQ36219245
Sequestration and release of basic fibroblast growth factorQ36463376
Dyssegmental dysplasias: clinical, radiographic, and morphologic evidence of heterogeneityQ39775578
Basement membrane (type IV) collagenQ40553053
Epidermal tissue regeneration and stromal interaction in HaCaT cells is initiated by TGF-alphaQ40644434
Vitamin D enhances mitogenesis mediated by keratinocyte growth factor receptor in keratinocytesQ40645723
Mutations uncouple human fibroblast growth factor (FGF)-7 biological activity and receptor binding and support broad specificity in the secondary receptor binding site of FGFs.Q40915825
Human perlecan immunopurified from different endothelial cell sources has different adhesive properties for vascular cells.Q40947660
Epidermal differentiation and basement membrane formation by HaCaT cells in surface transplantsQ41042865
Identification of glypican as a dual modulator of the biological activity of fibroblast growth factorsQ41110684
Involvement of heparan sulfate and related molecules in sequestration and growth promoting activity of fibroblast growth factorQ41140266
Supramolecular assembly of basement membranesQ41147111
Epidermis generated in vitro: practical considerations and applicationsQ41156888
A role for the perlecan protein core in the activation of the keratinocyte growth factor receptorQ41895425
Keratinocyte growth factor inhibits cross-linked envelope formation and nucleosomal fragmentation in cultured human keratinocytesQ42517338
Mutual induction of growth factor gene expression by epidermal-dermal cell interactionQ42769779
Expression of mouse telomerase reverse transcriptase during development, differentiation and proliferationQ42830375
Comparison of gene expression profiles in human keratinocyte mono-layer cultures, reconstituted epidermis and normal human skin; transcriptional effects of retinoid treatments in reconstituted human epidermisQ43959137
Non-viral liposomal keratinocyte growth factor (KGF) cDNA gene transfer improves dermal and epidermal regeneration through stimulation of epithelial and mesenchymal factorsQ45888073
Apoptosis of endothelial cells triggers a caspase-dependent anti-apoptotic paracrine loop active on VSMC.Q51025323
Dyssegmental dysplasia, Silverman-Handmaker type, is caused by functional null mutations of the perlecan geneQ52137443
There is binding of collagen IV to beta 1 integrin during early skin basement membrane assemblyQ52533549
Dynamics of Basement Membrane Formation by Keratinocyte–Fibroblast Interactions in Organotypic Skin CultureQ53435976
P433issue8
P407language of work or nameEnglishQ1860
P921main subjectkeratinocyteQ1473931
P304page(s)5178-5187
P577publication date2005-11-02
P1433published inJournal of Biological ChemistryQ867727
P1476titleTargeting perlecan in human keratinocytes reveals novel roles for perlecan in epidermal formation
P478volume281

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cites work (P2860)
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