scholarly article | Q13442814 |
P50 | author | Michiyuki Matsuda | Q51727894 |
P2093 | author name string | M Matsuda | |
M Shibuya | |||
K Nagashima | |||
S Tanaka | |||
H Hasegawa | |||
T Kurata | |||
N Gotoh | |||
E Kiyokawa | |||
P2860 | cites work | C3G, a guanine nucleotide-releasing protein expressed ubiquitously, binds to the Src homology 3 domains of CRK and GRB2/ASH proteins | Q24305258 |
A novel signaling molecule, p130, forms stable complexes in vivo with v-Crk and v-Src in a tyrosine phosphorylation-dependent manner | Q24318312 | ||
Association of the v-crk oncogene product with phosphotyrosine-containing proteins and protein kinase activity | Q24558728 | ||
Cloning of ASH, a ubiquitous protein composed of one Src homology region (SH) 2 and two SH3 domains, from human and rat cDNA libraries | Q24563818 | ||
CRK protein binds to two guanine nucleotide-releasing proteins for the Ras family and modulates nerve growth factor-induced activation of Ras in PC12 cells | Q24610534 | ||
Expression of the v-crk oncogene product in PC12 cells results in rapid differentiation by both nerve growth factor- and epidermal growth factor-dependent pathways | Q24613828 | ||
Two species of human CRK cDNA encode proteins with distinct biological activities | Q24629936 | ||
An analysis of vertebrate mRNA sequences: intimations of translational control | Q24642530 | ||
Identification of Rap1 as a target for the Crk SH3 domain-binding guanine nucleotide-releasing factor C3G | Q24651040 | ||
Signal transduction from the extracellular matrix | Q24675031 | ||
Protein modules and signalling networks | Q27860694 | ||
Efficient selection for high-expression transfectants with a novel eukaryotic vector | Q27860810 | ||
Association of Ash/Grb-2 with dynamin through the Src homology 3 domain | Q28250199 | ||
CLUSTAL: a package for performing multiple sequence alignment on a microcomputer | Q28293854 | ||
The SH3 domain of Crk binds specifically to a conserved proline-rich motif in Eps15 and Eps15R | Q28304242 | ||
SH2 and SH3 domains as molecular adhesives: the interactions of Crk and Abl | Q28307277 | ||
A novel viral oncogene with structural similarity to phospholipase C | Q28307371 | ||
The proto-oncogene product c-Cbl becomes tyrosine phosphorylated by stimulation with GM-CSF or Epo and constitutively binds to the SH3 domain of Grb2/Ash in human hematopoietic cells | Q28609032 | ||
Four proline-rich sequences of the guanine-nucleotide exchange factor C3G bind with unique specificity to the first Src homology 3 domain of Crk | Q28609801 | ||
Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase | Q28646514 | ||
Integrins and signal transduction pathways: the road taken | Q29547895 | ||
Modular binding domains in signal transduction proteins | Q29617351 | ||
The GTPase dynamin binds to and is activated by a subset of SH3 domains | Q29618141 | ||
Affinity and specificity requirements for the first Src homology 3 domain of the Crk proteins | Q30193419 | ||
Cellular proteins binding to the first Src homology 3 (SH3) domain of the proto-oncogene product c-Crk indicate Crk-specific signaling pathways | Q30193501 | ||
Crk interacts with tyrosine-phosphorylated p116 upon T cell activation | Q30193645 | ||
The C-terminal SH3 domain of the mouse c-Crk protein negatively regulates tyrosine-phosphorylation of Crk associated p130 in rat 3Y1 cells. | Q30194289 | ||
Structure and function of the SH3 domain | Q30194603 | ||
Identification and Characterization of a High-Affinity Interaction Between v-Crk and Tyrosine-Phosphorylated Paxillin in CT10-Transformed Fibroblasts | Q30194902 | ||
Both the SH2 and SH3 domains of human CRK protein are required for neuronal differentiation of PC12 cells | Q30194957 | ||
The product of the cellular crk gene consists primarily of SH2 and SH3 regions | Q30195339 | ||
Tyrosine-phosphorylated epidermal growth factor receptor and cellular p130 provide high affinity binding substrates to analyze Crk-phosphotyrosine-dependent interactions in vitro | Q30195371 | ||
Mutagenic analysis of the v-crk oncogene: requirement for SH2 and SH3 domains and correlation between increased cellular phosphotyrosine and transformation | Q30195822 | ||
Binding of Transforming Protein, P47 gag-crk , to a Broad Range of Phosphotyrosine-containing Proteins | Q30195844 | ||
pp125FAK-dependent tyrosine phosphorylation of paxillin creates a high-affinity binding site for Crk | Q30452729 | ||
Signal transduction through integrins: a central role for focal adhesion kinase? | Q30464970 | ||
Focal adhesion kinase and associated proteins | Q30465310 | ||
Signal transduction in T lymphocytes using a conditional allele of Sos | Q33871535 | ||
Epidermal growth factor-receptor mutant lacking the autophosphorylation sites induces phosphorylation of Shc protein and Shc-Grb2/ASH association and retains mitogenic activity | Q34914079 | ||
Membrane-targeting potentiates guanine nucleotide exchange factor CDC25 and SOS1 activation of Ras transforming activity | Q35722860 | ||
Human Colon Carcinoma Ki-ras2 Oncogene and Its Corresponding Proto-Oncogene | Q36946669 | ||
Membrane targeting of the nucleotide exchange factor Sos is sufficient for activating the Ras signaling pathway. | Q39481540 | ||
Integrin-mediated cell adhesion promotes tyrosine phosphorylation of p130Cas, a Src homology 3-containing molecule having multiple Src homology 2-binding motifs | Q41334070 | ||
The hunt for Ras targets | Q59095565 | ||
P433 | issue | 4 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | cell morphology | Q66568582 |
P304 | page(s) | 1770-6 | |
P577 | publication date | 1996-04-01 | |
P1433 | published in | Molecular and Cellular Biology | Q3319478 |
P1476 | title | DOCK180, a major CRK-binding protein, alters cell morphology upon translocation to the cell membrane | |
P478 | volume | 16 |
Q34623781 | A Minimal Rac Activation Domain in the Unconventional Guanine Nucleotide Exchange Factor Dock180 |
Q24296060 | A Steric-inhibition model for regulation of nucleotide exchange via the Dock180 family of GEFs |
Q24535521 | A direct interaction between JNK1 and CrkII is critical for Rac1-induced JNK activation |
Q24539212 | A novel and evolutionarily conserved PtdIns(3,4,5)P3-binding domain is necessary for DOCK180 signalling |
Q30008856 | A pre-metazoan origin of the CRK gene family and co-opted signaling network |
Q34048799 | Activation of Cdc42 is necessary for sustained oscillations of Ca2+ and PIP2 stimulated by antigen in RBL mast cells |
Q35570177 | Activation of Rac1 by Src-dependent phosphorylation of Dock180(Y1811) mediates PDGFRα-stimulated glioma tumorigenesis in mice and humans |
Q22007972 | Activation of Rac1 by a Crk SH3-binding protein, DOCK180 |
Q40525953 | Activation of Rac1 by paxillin-Crk-DOCK180 signaling complex is antagonized by Rap1 in migrating NBT-II cells |
Q36854898 | Activation of Rac1 by the guanine nucleotide exchange factor Dck1 is required for invasive filamentous growth in the pathogen Candida albicans |
Q27657391 | Activation of Rho GTPases by DOCK exchange factors is mediated by a nucleotide sensor |
Q34324446 | Activation of rac and cdc42 video imaged by fluorescent resonance energy transfer-based single-molecule probes in the membrane of living cells |
Q30168248 | Activation of the focal adhesion kinase signaling pathway by structural alterations in the carboxyl-terminal region of c-Crk II. |
Q30307290 | Alterations in the focal adhesion kinase/Src signal transduction pathway correlate with increased migratory capacity of prostate carcinoma cells |
Q33940235 | An appetite for apoptotic cells? Controversies and challenges |
Q24304056 | An isoform of GTPase regulator DOCK4 localizes to the stereocilia in the inner ear and binds to harmonin (USH1C) |
Q24313047 | Ankyrin repeat domain 28 (ANKRD28), a novel binding partner of DOCK180, promotes cell migration by regulating focal adhesion formation |
Q47071234 | Antisocial, an intracellular adaptor protein, is required for myoblast fusion in Drosophila |
Q35719265 | Apoptotic cell and phagocyte interplay: recognition and consequences in different cell systems |
Q30277892 | Apoptotic cell recognition receptors and scavenger receptors |
Q30167608 | Apoptotic regulation by the Crk adapter protein mediated by interactions with Wee1 and Crm1/exportin |
Q28298373 | B cell antigen receptor signaling induces the formation of complexes containing the Crk adapter proteins |
Q28257171 | BCR/ABL-induced leukemogenesis causes phosphorylation of Hef1 and its association with Crkl |
Q28144317 | Beta 1-integrin-mediated cell signaling in T lymphocytes |
Q30008899 | Binding Mechanism of the N-Terminal SH3 Domain of CrkII and Proline-Rich Motifs in cAbl |
Q28306511 | C-terminal SH3 domain of CrkII regulates the assembly and function of the DOCK180/ELMO Rac-GEF |
Q39750201 | C. elegans CED-12 acts in the conserved crkII/DOCK180/Rac pathway to control cell migration and cell corpse engulfment. |
Q24336487 | C. elegans phagocytosis and cell-migration protein CED-5 is similar to human DOCK180 |
Q24311510 | CAS/Crk coupling serves as a "molecular switch" for induction of cell migration |
Q30306838 | CAS/Crk signalling mediates uptake of Yersinia into human epithelial cells |
Q24291780 | CED-12/ELMO, a novel member of the CrkII/Dock180/Rac pathway, is required for phagocytosis and cell migration |
Q39749591 | CED-2/CrkII and CED-10/Rac control phagocytosis and cell migration in Caenorhabditis elegans |
Q64900712 | CRKII overexpression promotes the in vitro proliferation, migration and invasion potential of murine hepatocarcinoma Hca-P cells. |
Q38112644 | Cbl-family proteins as regulators of cytoskeleton-dependent phenomena |
Q35107552 | Cell and molecular biology of myoblast fusion |
Q30437225 | Cell migration is regulated by platelet-derived growth factor receptor endocytosis |
Q29616711 | Cell migration: Rho GTPases lead the way |
Q30439052 | Characterization of a novel interaction between ELMO1 and ERM proteins |
Q33891506 | Chat, a Cas/HEF1-associated adaptor protein that integrates multiple signaling pathways |
Q30433781 | Clearance of apoptotic cells: implications in health and disease |
Q54231841 | Comparison of normal human skin gene expression using cDNA microarrays. |
Q30176172 | Constitutive association of EGF receptor with the CrkII-23 mutant that inhibits transformation of NRK cells by EGF and TGF-beta |
Q33744987 | Control of cell migration during Caenorhabditis elegans development |
Q30157305 | Crk adaptor protein-induced phosphorylation of Gab1 on tyrosine 307 via Src is important for organization of focal adhesions and enhanced cell migration |
Q41942048 | Crk and CrkL adaptor proteins: networks for physiological and pathological signaling |
Q30155850 | Crk and CrkL present with different expression and significance in epithelial ovarian carcinoma |
Q30167857 | Crk family adaptors-signalling complex formation and biological roles |
Q48185910 | Crk proteins transduce FGF signaling to promote lens fiber cell elongation |
Q30175335 | CrkL mediates Ras-dependent activation of the Raf/ERK pathway through the guanine nucleotide exchange factor C3G in hematopoietic cells stimulated with erythropoietin or interleukin-3. |
Q30175868 | DEF-1, a novel Src SH3 binding protein that promotes adipogenesis in fibroblastic cell lines |
Q24304336 | DOCK2 mediates T cell receptor-induced activation of Rac2 and IL-2 transcription |
Q28182054 | DOCK4, a GTPase activator, is disrupted during tumorigenesis |
Q28116715 | DOCK5 and DOCK1 regulate Caco-2 intestinal epithelial cell spreading and migration on collagen IV |
Q30008878 | Dedicator of Cytokinesis 2 in Cell Signaling Regulation and Disease Development |
Q30485463 | Dictyostelium Dock180-related RacGEFs regulate the actin cytoskeleton during cell motility |
Q22253384 | Differential interaction of CrkII adaptor protein with platelet-derived growth factor alpha- and beta-receptors is determined by its internal tyrosine phosphorylation |
Q24678407 | Disruption of a novel member of a sodium/hydrogen exchanger family and DOCK3 is associated with an attention deficit hyperactivity disorder-like phenotype |
Q42374728 | Distinct molecular pathways mediate glial activation and engulfment of axonal debris after axotomy |
Q30157067 | Distinct roles for Crk adaptor isoforms in actin reorganization induced by extracellular signals |
Q28187402 | Dock180 and ELMO1 proteins cooperate to promote evolutionarily conserved Rac-dependent cell migration |
Q28296792 | Dock180-ELMO cooperation in Rac activation |
Q52671777 | Dock2 in the development of inflammation and cancer. |
Q28267493 | Dock4 is regulated by RhoG and promotes Rac-dependent cell migration |
Q34596325 | Dock6, a Dock-C subfamily guanine nucleotide exchanger, has the dual specificity for Rac1 and Cdc42 and regulates neurite outgrowth |
Q53175756 | Dock7: a GEF for Rho-family GTPases and a novel myosin VI-binding partner in neuronal PC12 cells. |
Q37230539 | Drosophila ELMO/CED-12 interacts with Myoblast city to direct myoblast fusion and ommatidial organization |
Q24676790 | Drosophila myoblast city encodes a conserved protein that is essential for myoblast fusion, dorsal closure, and cytoskeletal organization |
Q24623558 | ELMO1 and Dock180, a bipartite Rac1 guanine nucleotide exchange factor, promote human glioma cell invasion |
Q27340506 | Early mechanisms of pathobiology are revealed by transcriptional temporal dynamics in hippocampal CA1 neurons of prion infected mice |
Q52655711 | Ecdysone regulates morphogenesis and function of Malpighian tubules in Drosophila melanogaster through EcR-B2 isoform. |
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Q30445079 | Engulfment of apoptotic cells: signals for a good meal |
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Q55055558 | Epidermal growth factor-dependent dissociation of CrkII proto-oncogene product from the epidermal growth factor receptor in human glioma cells. |
Q24648256 | ErbB2 directly activates the exchange factor Dock7 to promote Schwann cell migration |
Q33744526 | Essential genes for myoblast fusion in Drosophila embryogenesis |
Q30176064 | Evidence that DOCK180 up-regulates signals from the CrkII-p130(Cas) complex |
Q21261467 | Examination of NRCAM, LRRN3, KIAA0716, and LAMB1 as autism candidate genes |
Q92661891 | FAK-Dependent Cell Motility and Cell Elongation |
Q34300201 | Focal adhesions require catalytic activity of Src family kinases to mediate integrin-matrix adhesion |
Q34056991 | Function of Rho family proteins in actin dynamics during phagocytosis and engulfment |
Q26998955 | Functional roles of fibroblast growth factor receptors (FGFRs) signaling in human cancers |
Q24633334 | GEF what? Dock180 and related proteins help Rac to polarize cells in new ways |
Q74543058 | GEF without a Dbl domain? |
Q30436337 | GRASP and IPCEF promote ARF-to-Rac signaling and cell migration by coordinating the association of ARNO/cytohesin 2 with Dock180. |
Q31150208 | Genetic and functional evidence for a locus controlling otitis media at chromosome 10q26.3. |
Q37112620 | Genetic control of muscle development: learning from Drosophila |
Q43762442 | Guidance of cell migration by the Drosophila PDGF/VEGF receptor |
Q28512928 | Haematopoietic cell-specific CDM family protein DOCK2 is essential for lymphocyte migration |
Q24550885 | Hic-5-reduced cell spreading on fibronectin: competitive effects between paxillin and Hic-5 through interaction with focal adhesion kinase |
Q33314672 | Host-pathogen systems biology: logical modelling of hepatocyte growth factor and Helicobacter pylori induced c-Met signal transduction |
Q38284377 | I'm coming to GEF you: Regulation of RhoGEFs during cell migration |
Q28203896 | Identification and kinetic analysis of the interaction between Nck-2 and DOCK180 |
Q27219697 | Identification of a Drosophila homologue to vertebrate Crk by interaction with MBC |
Q32066807 | Identification of novel Drosophila neural precursor genes using a differential embryonic head cDNA screen |
Q30442947 | Identification of two signaling submodules within the CrkII/ELMO/Dock180 pathway regulating engulfment of apoptotic cells. |
Q24649740 | Identification of tyrosine residues on ELMO1 that are phosphorylated by the Src-family kinase Hck. |
Q40051860 | Identification, Characterization, and Structure of Tm16 from Trichuris muris |
Q35563190 | Immunohistochemichal Assessment of the CrkII Proto-oncogene Expression in Common Malignant Salivary Gland Tumors and Pleomorphic Adenoma |
Q28296782 | In vitro guanine nucleotide exchange activity of DHR-2/DOCKER/CZH2 domains |
Q24533233 | Insulin regulates the dynamic balance between Ras and Rap1 signaling by coordinating the assembly states of the Grb2-SOS and CrkII-C3G complexes. |
Q35547365 | Integrin signaling to the actin cytoskeleton. |
Q30448862 | Integrin-mediated mechanotransduction pathway of low-intensity continuous ultrasound in human chondrocytes |
Q30423615 | Integrins and extracellular matrix in mechanotransduction |
Q28281847 | Interaction between the amino-terminal SH3 domain of CRK and its natural target proteins |
Q30009578 | Interaction of crk with Myosin-1c participates in fibronectin-induced cell spreading |
Q37998461 | Interplay of polarity proteins and GTPases in T-lymphocyte function. |
Q28272714 | Interplay of the proto-oncogene proteins CrkL and CrkII in insulin-like growth factor-I receptor-mediated signal transduction |
Q40313652 | Involvement of adaptor protein Crk in malignant feature of human ovarian cancer cell line MCAS. |
Q30175432 | Involvement of the adapter protein CRKL in integrin-mediated adhesion |
Q30009282 | Iterative tyrosine phosphorylation controls non-canonical domain utilization in Crk. |
Q24680571 | Listeria monocytogenes exploits normal host cell processes to spread from cell to cell |
Q30453539 | Mechanisms of CAS substrate domain tyrosine phosphorylation by FAK and Src |
Q24532348 | Membrane recruitment of DOCK180 by binding to PtdIns(3,4,5)P3 |
Q30175408 | Membrane-targeting of signalling molecules by SH2/SH3 domain-containing adaptor proteins |
Q30009961 | Models of crk adaptor proteins in cancer |
Q30165527 | Molecular and immunohistochemical analysis of signaling adaptor protein Crk in human cancers |
Q27668010 | Multiple Factors Confer Specific Cdc42 and Rac Protein Activation by Dedicator of Cytokinesis (DOCK) Nucleotide Exchange Factors |
Q34574378 | Muscle differentiation: how two cells become one. |
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Q24596003 | Myoblast city, the Drosophila homolog of DOCK180/CED-5, is required in a Rac signaling pathway utilized for multiple developmental processes |
Q37147237 | Myoblast fusion in fly and vertebrates: new genes, new processes and new perspectives. |
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Q30481422 | Myoblasts and macrophages share molecular components that contribute to cell-cell fusion |
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Q53198380 | Overexpression of dedicator of cytokinesis I (Dock180) in ovarian cancer correlated with aggressive phenotype and poor patient survival. |
Q37592539 | PVR plays a critical role via JNK activation in thorax closure during Drosophila metamorphosis |
Q24646926 | Parallel phosphatidylinositol 3-kinase (PI3K)-dependent and Src-dependent pathways lead to CXCL8-mediated Rac2 activation and chemotaxis |
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Q30416374 | Phosphatidylserine receptor BAI1 and apoptotic cells as new promoters of myoblast fusion |
Q28274831 | Phosphorylation of CrkII adaptor protein at tyrosine 221 by epidermal growth factor receptor |
Q30009346 | Phosphorylation of Dok1 by Abl family kinases inhibits CrkI transforming activity |
Q30175229 | Phosphorylation of tyrosine residues 31 and 118 on paxillin regulates cell migration through an association with CRK in NBT-II cells |
Q33937108 | Plexina1 autoinhibition by the plexin sema domain. |
Q37119206 | Prenylation and membrane localization of Cdc42 are essential for activation by DOCK7. |
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Q30156056 | Proteins that bind the Src homology 3 domain of CrkI have distinct roles in Crk transformation |
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Q30433703 | Rac1 is essential for basement membrane-dependent epiblast survival |
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Q36306178 | Reduced DOCK4 expression leads to erythroid dysplasia in myelodysplastic syndromes. |
Q30157247 | Regulation of focal adhesion and cell migration by ANKRD28-DOCK180 interaction |
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