scholarly article | Q13442814 |
P50 | author | Yoshinori Fukui | Q57167803 |
Jean-François Côté | Q89637925 | ||
Akihiko Nishikimi | Q39867863 | ||
P2093 | author name string | Yasunori Kanaho | |
Fumiyuki Sanematsu | |||
Yoshihiko Tanaka | |||
Tsunaki Hongu | |||
Mayuki Watanabe | |||
P2860 | cites work | CED-12/ELMO, a novel member of the CrkII/Dock180/Rac pathway, is required for phagocytosis and cell migration | Q24291780 |
Unconventional Rac-GEF activity is mediated through the Dock180-ELMO complex | Q24301883 | ||
A common lipid links Mfn-mediated mitochondrial fusion and SNARE-regulated exocytosis | Q24306318 | ||
An alpha-helical extension of the ELMO1 pleckstrin homology domain mediates direct interaction to DOCK180 and is critical in Rac signaling | Q24310171 | ||
STAT5 as a molecular regulator of proliferation, differentiation and apoptosis in hematopoietic cells | Q24534351 | ||
A novel and evolutionarily conserved PtdIns(3,4,5)P3-binding domain is necessary for DOCK180 signalling | Q24539212 | ||
DOCK180, a major CRK-binding protein, alters cell morphology upon translocation to the cell membrane | Q24650136 | ||
Molecular mechanisms of N-formyl-methionyl-leucyl-phenylalanine-induced superoxide generation and degranulation in mouse neutrophils: phospholipase D is dispensable | Q42531338 | ||
5-Fluoro-2-indolyl des-chlorohalopemide (FIPI), a phospholipase D pharmacological inhibitor that alters cell spreading and inhibits chemotaxis | Q42805401 | ||
Phosphatidic acid that accumulates in platelet-derived growth factor-stimulated Balb/c 3T3 cells is a potential mitogenic signal | Q42818777 | ||
Phospholipase D2-generated phosphatidic acid couples EGFR stimulation to Ras activation by Sos. | Q42828551 | ||
Differential Roles of WAVE1 and WAVE2 in Dorsal and Peripheral Ruffle Formation for Fibroblast Cell Migration | Q44612166 | ||
T helper type 2 differentiation and intracellular trafficking of the interleukin 4 receptor-alpha subunit controlled by the Rac activator Dock2. | Q50889452 | ||
Macropinocytosis | Q58323386 | ||
Blockage of chemotactic peptide-induced stimulation of neutrophils by wortmannin as a result of selective inhibition of phosphatidylinositol 3-kinase | Q72237914 | ||
DOCK2 is a Rac activator that regulates motility and polarity during neutrophil chemotaxis | Q24683000 | ||
Structural Basis of Membrane Targeting by the Dock180 Family of Rho Family Guanine Exchange Factors (Rho-GEFs) | Q27659933 | ||
Multiple Factors Confer Specific Cdc42 and Rac Protein Activation by Dedicator of Cytokinesis (DOCK) Nucleotide Exchange Factors | Q27668010 | ||
Cell migration: integrating signals from front to back | Q27860670 | ||
DOCK2 regulates Rac activation and cytoskeletal reorganization through interaction with ELMO1 | Q28182421 | ||
Dock180 and ELMO1 proteins cooperate to promote evolutionarily conserved Rac-dependent cell migration | Q28187402 | ||
Identification and kinetic analysis of the interaction between Nck-2 and DOCK180 | Q28203896 | ||
Identification of an evolutionarily conserved superfamily of DOCK180-related proteins with guanine nucleotide exchange activity | Q28214812 | ||
Phospholipase D | Q28253553 | ||
Phospholipase D: a lipid centric review | Q28270831 | ||
Characterization of two alternately spliced forms of phospholipase D1. Activation of the purified enzymes by phosphatidylinositol 4,5-bisphosphate, ADP-ribosylation factor, and Rho family monomeric GTP-binding proteins and protein kinase C-alpha | Q28302448 | ||
Haematopoietic cell-specific CDM family protein DOCK2 is essential for lymphocyte migration | Q28512928 | ||
DOCK2 is essential for antigen-induced translocation of TCR and lipid rafts, but not PKC-theta and LFA-1, in T cells | Q28593591 | ||
PIP2 and PIP3: complex roles at the cell surface | Q28609413 | ||
Guanine nucleotide exchange factors for Rho GTPases: turning on the switch | Q29618403 | ||
Netrin signal transduction and the guanine nucleotide exchange factor DOCK180 in attractive signaling | Q30443470 | ||
Rac1-null mouse embryonic fibroblasts are motile and respond to platelet-derived growth factor | Q30477161 | ||
A dynamin-cortactin-Arp2/3 complex mediates actin reorganization in growth factor-stimulated cells | Q30477658 | ||
CtBP1/BARS is an activator of phospholipase D1 necessary for agonist-induced macropinocytosis | Q30486803 | ||
Sequential signaling in plasma-membrane domains during macropinosome formation in macrophages | Q30489942 | ||
The atypical Rac activator Dock180 (Dock1) regulates myoblast fusion in vivo | Q33372285 | ||
Selective control of type I IFN induction by the Rac activator DOCK2 during TLR-mediated plasmacytoid dendritic cell activation. | Q33794944 | ||
Zizimin1, a novel Cdc42 activator, reveals a new GEF domain for Rho proteins | Q34143927 | ||
Heterogeneity of phosphatidic acid levels and distribution at the plasma membrane in living cells as visualized by a Föster resonance energy transfer (FRET) biosensor | Q34285394 | ||
Rab5 is a signalling GTPase involved in actin remodelling by receptor tyrosine kinases | Q34321861 | ||
Differential requirement for DOCK2 in migration of plasmacytoid dendritic cells versus myeloid dendritic cells | Q34736661 | ||
Foot and mouth: podosomes, invadopodia and circular dorsal ruffles | Q35887297 | ||
Phosphatidic acid- and phosphatidylserine-binding proteins | Q36453653 | ||
Get off my back! Rapid receptor internalization through circular dorsal ruffles. | Q36673646 | ||
Key roles for the lipid signaling enzyme phospholipase d1 in the tumor microenvironment during tumor angiogenesis and metastasis | Q37041152 | ||
DOCK180 is a Rac activator that regulates cardiovascular development by acting downstream of CXCR4. | Q39657420 | ||
Sequential regulation of DOCK2 dynamics by two phospholipids during neutrophil chemotaxis. | Q39867658 | ||
Opening up on ELMO regulation: New insights into the control of Rac signaling by the DOCK180/ELMO complex | Q40647051 | ||
P433 | issue | 12 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 8092-8100 | |
P577 | publication date | 2013-01-29 | |
P1433 | published in | Journal of Biological Chemistry | Q867727 |
P1476 | title | Phosphatidic acid-dependent recruitment and function of the Rac activator DOCK1 during dorsal ruffle formation | |
P478 | volume | 288 |
Q91936025 | A real-time, click chemistry imaging approach reveals stimulus-specific subcellular locations of phospholipase D activity |
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Q36268883 | DOCK2 and DOCK5 act additively in neutrophils to regulate chemotaxis, superoxide production, and extracellular trap formation |
Q30582096 | DOCK5 functions as a key signaling adaptor that links FcεRI signals to microtubule dynamics during mast cell degranulation |
Q28066088 | Diacylglycerol Kinases: Shaping Diacylglycerol and Phosphatidic Acid Gradients to Control Cell Polarity |
Q38713729 | ELMO proteins transduce G protein-coupled receptor signal to control reorganization of actin cytoskeleton in chemotaxis of eukaryotic cells |
Q47593066 | G-Protein Gα13 Functions with Abl Kinase to Regulate Actin Cytoskeletal Reorganization |
Q101476135 | Genetic analyses in mouse fibroblast and melanoma cells demonstrate novel roles for PDGF-AB ligand and PDGF receptor alpha |
Q38196631 | Insights into the biological functions of Dock family guanine nucleotide exchange factors |
Q58586388 | Macropinocytosis: New Insights Into Its Underappreciated Role in Innate Immune Cell Surveillance |
Q61811029 | Phosphatidic Acid: From Pleiotropic Functions to Neuronal Pathology |
Q37665324 | Phospholipase D (PLD) drives cell invasion, tumor growth and metastasis in a human breast cancer xenograph model |
Q47386895 | Proliferative and metastatic roles for Phospholipase D in mouse models of cancer. |
Q37721163 | The focal adhesion-associated proteins DOCK5 and GIT2 comprise a rheostat in control of epithelial invasion. |
Q38936522 | The life cycle of phagosomes: formation, maturation, and resolution |
Q28082479 | The phospholipase D superfamily as therapeutic targets |
Q36909364 | The transcription factors Slug (SNAI2) and Snail (SNAI1) regulate phospholipase D (PLD) promoter in opposite ways towards cancer cell invasion |
Q27345292 | p53 Down regulates PDGF-induced formation of circular dorsal ruffles in rat aortic smooth muscle cells |
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