Phosphatidic Acid: From Pleiotropic Functions to Neuronal Pathology

scientific article published on 23 January 2019

Phosphatidic Acid: From Pleiotropic Functions to Neuronal Pathology is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3389/FNCEL.2019.00002
P932PMC publication ID6351798
P698PubMed publication ID30728767

P50authorHervé MoineQ42150752
Nicolas VitaleQ46428894
P2093author name stringEmeline Tanguy
Qili Wang
P2860cites workRare coding variants in the phospholipase D3 gene confer risk for Alzheimer's diseaseQ24312938
PIP5K-driven PtdIns(4,5)P2 synthesis: regulation and cellular functionsQ24314508
ADP ribosylation factor 6 (ARF6) promotes acrosomal exocytosis by modulating lipid turnover and Rab3A activation.Q27313594
Phosphatidylinositol 4-phosphate 5-kinase alpha is a downstream effector of the small G protein ARF6 in membrane ruffle formationQ28139699
Phospholipase D: a lipid centric reviewQ28270831
Phospholipase D1: a key factor for the exocytotic machinery in neuroendocrine cellsQ28364949
Phospholipase D1 is associated with amyloid precursor protein in Alzheimer's diseaseQ40263107
The simultaneous production of phosphatidic acid and diacylglycerol is essential for the translocation of protein kinase Cepsilon to the plasma membrane in RBL-2H3 cellsQ40286905
Dynamics and function of phospholipase D and phosphatidic acid during phagocytosisQ40312376
HS1BP3 negatively regulates autophagy by modulation of phosphatidic acid levelsQ42067218
Role of phosphoinositide signaling in the control of insulin exocytosisQ42482214
Pak1 regulates dendritic branching and spine formationQ42511375
A role for phosphatidic acid in COPI vesicle fission yields insights into Golgi maintenanceQ42575658
PLD3 variants in population studiesQ42725567
Phosphatidic acid-dependent recruitment and function of the Rac activator DOCK1 during dorsal ruffle formationQ42752703
An essential role for phospholipase D in the recruitment of vesicle amine transport protein-1 to membranes in human neutrophilsQ45199854
Comparative Characterization of Phosphatidic Acid Sensors and Their Localization during Frustrated PhagocytosisQ46428843
PLD3 in non-familial Alzheimer's diseaseQ48251025
The carboxy-terminal tail domain of vinculin contains a cryptic binding site for acidic phospholipidsQ49270032
The synaptic ribbon is a site of phosphatidic acid generation in ribbon synapses.Q50508564
PLD3 and sporadic Alzheimer's disease risk.Q53475066
Phosphatidic Acid-Mediated Signaling Regulates Microneme Secretion in Toxoplasma.Q54209312
The phosphatidic acid paradox: Too many actions for one molecule class? Lessons from plants.Q54977860
Review and gap analysis: molecular pathways leading to fetal alcohol spectrum disordersQ55162778
Protein⁻Phospholipid Interaction Motifs: A Focus on Phosphatidic Acid.Q55514290
Antineutrophil Cytoplasm Antibody-Stimulated Neutrophil Adhesion Depends on Diacylglycerol Kinase-Catalyzed Phosphatidic Acid FormationQ57268316
Phospholipase D1 Production of Phosphatidic Acid at the Plasma Membrane Promotes Exocytosis of Large Dense-core Granules at a Late StageQ58025406
Diacylglycerol stimulates acrosomal exocytosis by feeding into a PKC- and PLD1-dependent positive loop that continuously supplies phosphatidylinositol 4,5-bisphosphateQ58423681
Ral Isoforms Are Implicated in Fc R-Mediated Phagocytosis: Activation of Phospholipase D by RalAQ58423692
Phospholipase D1 is specifically required for regulated secretion of von Willebrand factor from endothelial cellsQ58423701
Of local translation control and lipid signaling in neuronsQ91820352
Membrane targeting of p21-activated kinase 1 (PAK1) induces neurite outgrowth from PC12 cellsQ28579492
Phospholipase d2 ablation ameliorates Alzheimer's disease-linked synaptic dysfunction and cognitive deficitsQ30497694
Phospholipase D is a target for inhibition of astroglial proliferation by ethanol.Q30968562
A role for phospholipase D1 in neurotransmitter release.Q33953145
Modulation of membrane curvature by phosphatidic acid and lysophosphatidic acidQ34186047
The Coffin-Lowry syndrome-associated protein RSK2 regulates neurite outgrowth through phosphorylation of phospholipase D1 (PLD1) and synthesis of phosphatidic acid.Q34391853
Phospholipase D1 corrects impaired betaAPP trafficking and neurite outgrowth in familial Alzheimer's disease-linked presenilin-1 mutant neuronsQ34478763
SNARE-catalyzed fusion events are regulated by Syntaxin1A-lipid interactionsQ34713785
Live-cell imaging of phosphatidic acid dynamics in pollen tubes visualized by Spo20p-derived biosensor.Q35153444
ESI-MS/MS and MALDI-IMS Localization Reveal Alterations in Phosphatidic Acid, Diacylglycerol, and DHA in Glioma Stem Cell XenograftsQ35603809
PLD1 participates in BDNF-induced signalling in cortical neuronsQ36123489
Functions and pathophysiological roles of phospholipase D in the brainQ36206662
Phospholipids stimulate phosphorylation of vinculin by the tyrosine-specific protein kinase of Rous sarcoma virusQ36306117
Phosphatidic acid regulation of PIPKI is critical for actin cytoskeletal reorganizationQ36387173
Phosphatidic acid- and phosphatidylserine-binding proteinsQ36453653
Phospholipase D activity regulates integrin-mediated cell spreading and migration by inducing GTP-Rac translocation to the plasma membraneQ36739944
The Coffin-Lowry syndrome-associated protein RSK2 is implicated in calcium-regulated exocytosis through the regulation of PLD1.Q36751561
Fragile X Mental Retardation Protein (FMRP) controls diacylglycerol kinase activity in neuronsQ37065097
Lipids in Regulated Exocytosis: What are They Doing?Q37178033
Phosphatidic acid signaling to mTOR: signals for the survival of human cancer cellsQ37380645
X-linked mental retardation: focus on synaptic function and plasticity.Q37381788
Phospholipase D in calcium-regulated exocytosis: lessons from chromaffin cellsQ37415686
Complex lipid requirements for SNARE- and SNARE chaperone-dependent membrane fusionQ37447913
Phospholipase D2 mediates survival signaling through direct regulation of Akt in glioblastoma cellsQ37459257
The Coffin-Lowry syndrome-associated protein RSK2 and neurosecretion.Q37808140
Lipid dynamics in exocytosis.Q37809768
Understanding of the roles of phospholipase D and phosphatidic acid through their binding partnersQ37972787
Phosphatidic acid in neuronal development: a node for membrane and cytoskeleton rearrangementsQ38238870
Lipids implicated in the journey of a secretory granule: from biogenesis to fusionQ38560548
Fragile X syndrome: Are signaling lipids the missing culprits?Q38946926
Phosphatidic acid and neurotransmissionQ38965341
Syntenin-ALIX exosome biogenesis and budding into multivesicular bodies are controlled by ARF6 and PLD2.Q39014592
Dual regulation of RA-RhoGAP activity by phosphatidic acid and Rap1 during neurite outgrowthQ39618349
Sequential regulation of DOCK2 dynamics by two phospholipids during neutrophil chemotaxis.Q39867658
Overexpression of phospholipase D enhances matrix metalloproteinase-2 expression and glioma cell invasion via protein kinase C and protein kinase A/NF-kappaB/Sp1-mediated signaling pathwaysQ39898182
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P407language of work or nameEnglishQ1860
P921main subjectpathologyQ7208
lipid signalingQ117982
phospholipase DQ700007
pleiotropyQ1134884
P304page(s)2
P577publication date2019-01-23
P1433published inFrontiers in Cellular NeuroscienceQ2131509
P1476titlePhosphatidic Acid: From Pleiotropic Functions to Neuronal Pathology
P478volume13

Reverse relations

cites work (P2860)
Q110178376Convergent use of phosphatidic acid for hepatitis C virus and SARS-CoV-2 replication organelle formation
Q98771694DDHD1, but Not DDHD2, Suppresses Neurite Outgrowth in SH-SY5Y and PC12 Cells by Regulating Protein Transport From Recycling Endosomes
Q92542864Protein Amphipathic Helix Insertion: A Mechanism to Induce Membrane Fission
Q92728609Robbing Host Phosphatidic Acid to Survive: A Strategy of a Fly Parasite
Q92715789The Structure and Function of Acylglycerophosphate Acyltransferase 4/ Lysophosphatidic Acid Acyltransferase Delta (AGPAT4/LPAATδ)

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