Siglec-F antibody administration to mice selectively reduces blood and tissue eosinophils

scientific article

Siglec-F antibody administration to mice selectively reduces blood and tissue eosinophils is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1111/J.1398-9995.2008.01709.X
P3181OpenCitations bibliographic resource ID3256238
P932PMC publication ID2726770
P698PubMed publication ID18699932
P5875ResearchGate publication ID23167698

P50authorPaul R. CrockerQ37830080
P2093author name stringY Yamada
C Jones
N Zimmermann
B S Bochner
M E Rothenberg
M L McBride
K D Cromie
S A Hudson
P2860cites workSiglec-8. A novel eosinophil-specific member of the immunoglobulin superfamilyQ22011026
Discovery of a fusion kinase in EOL-1 cells and idiopathic hypereosinophilic syndromeQ24670121
Defining the in vivo function of Siglec-F, a CD33-related Siglec expressed on mouse eosinophilsQ24678441
Interleukin-5 priming of human eosinophils alters siglec-8 mediated apoptosis pathwaysQ24685595
A tyrosine kinase created by fusion of the PDGFRA and FIP1L1 genes as a therapeutic target of imatinib in idiopathic hypereosinophilic syndromeQ27824793
Identification of SAF-2, a novel siglec expressed on eosinophils, mast cells, and basophilsQ28138424
Ligation of Siglec-8: a selective mechanism for induction of human eosinophil apoptosisQ28212692
Mouse Siglec-F and human Siglec-8 are functionally convergent paralogs that are selectively expressed on eosinophils and recognize 6'-sulfo-sialyl Lewis X as a preferred glycan ligandQ28257968
Inhibition of FcepsilonRI-dependent mediator release and calcium flux from human mast cells by sialic acid-binding immunoglobulin-like lectin 8 engagementQ28258592
Siglecs--the major subfamily of I-type lectinsQ28261393
Mechanism of Siglec-8-induced human eosinophil apoptosis: role of caspases and mitochondrial injuryQ28271835
EosinophiliaQ28272028
Siglecs and their roles in the immune systemQ28294469
Glycan array screening reveals a candidate ligand for Siglec-8Q28295084
The murine inhibitory receptor mSiglec-E is expressed broadly on cells of the innate immune system whereas mSiglec-F is restricted to eosinophilsQ28505221
Siglec-9 transduces apoptotic and nonapoptotic death signals into neutrophils depending on the proinflammatory cytokine environmentQ34411053
The FIP1L1-PDGFRA fusion gene cooperates with IL-5 to induce murine hypereosinophilic syndrome (HES)/chronic eosinophilic leukemia (CEL)-like diseaseQ35848279
Distinct endocytic mechanisms of CD22 (Siglec-2) and Siglec-F reflect roles in cell signaling and innate immunityQ35950210
Pharmacological regulation of human eosinophil apoptosisQ36230399
Eosinophilia in transgenic mice expressing interleukin 5.Q36353850
Eotaxin is required for the baseline level of tissue eosinophilsQ37395472
Immunoglobulin G: functional sitesQ39820837
PKC412 overcomes resistance to imatinib in a murine model of FIP1L1-PDGFRα-induced myeloproliferative disease.Q40643306
Molecular analysis of human Siglec-8 orthologs relevant to mouse eosinophils: identification of mouse orthologs of Siglec-5 (mSiglec-F) and Siglec-10 (mSiglec-G)Q47442854
Eosinophil levels in mice are significantly higher in small blood vessels than in large blood vessels.Q53690659
Binding of complement subcomponent Clq to mouse IgGl, IgG2a AND IgG2b: A novel Clq binding assayQ57564256
Intravenous immunoglobulin preparations contain anti–Siglec-8 autoantibodiesQ61959765
Modulation of eosinophil chemotaxis by interleukin-5Q67592198
Cytokine priming of the respiratory burst in human eosinophils is Ca2+ independent and accompanied by induction of tyrosine kinase activityQ70682248
Eosinophil infiltration and degranulation in normal human tissueQ77539954
P433issue9
P407language of work or nameEnglishQ1860
P921main subjectantibodyQ79460
P304page(s)1156-1163
P577publication date2008-09-01
P1433published inAllergyQ2699825
P1476titleSiglec-F antibody administration to mice selectively reduces blood and tissue eosinophils
P478volume63

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cites work (P2860)
Q36843245"Siglec"ting the allergic response for therapeutic targeting
Q35631650Additive anti-allergic effects of anti-interleukin-33 and anti-Siglec-F treatments in a murine model of allergic asthma
Q52320351Airway glycomic and allergic inflammatory consequences resulting from keratan sulfate galactose 6-O-sulfotransferase (CHST1) deficiency.
Q24645925Anti-Siglec-F antibody reduces allergen-induced eosinophilic inflammation and airway remodeling
Q37348437Basic and clinical immunology of Siglecs
Q38240474Biological Modulators in Eosinophilic Diseases.
Q37986851CD33-related siglecs as potential modulators of inflammatory responses
Q52619414Characterization of a novel mouse strain expressing human Siglec-8 only on eosinophils.
Q24608549Characterization of expression of glycan ligands for Siglec-F in normal mouse lungs
Q21284418Chronic OVA allergen challenged Siglec-F deficient mice have increased mucus, remodeling, and epithelial Siglec-F ligands which are up-regulated by IL-4 and IL-13
Q38210619Clinical implications and pathogenesis of esophageal remodeling in eosinophilic esophagitis
Q37431918Control of lung defence by mucins and macrophages: ancient defence mechanisms with modern functions
Q35441422Critical role of the neutrophil-associated high-affinity receptor for IgE in the pathogenesis of experimental cerebral malaria
Q36811319Cyclophilin D regulates necrosis, but not apoptosis, of murine eosinophils
Q24634555Developmental, malignancy-related, and cross-species analysis of eosinophil, mast cell, and basophil siglec-8 expression
Q35266949Early murine T-lymphocyte activation is accompanied by a switch from N-Glycolyl- to N-acetyl-neuraminic acid and generation of ligands for siglec-E
Q38662897Emerging Roles for Eosinophils in the Tumor Microenvironment
Q33758139Eosinophil survival and apoptosis in health and disease
Q41874438Eosinophil-derived IL-4 drives progression of myocarditis to inflammatory dilated cardiomyopathy
Q38353914Eosinophil-selective binding and proapoptotic effect in vitro of a synthetic Siglec-8 ligand, polymeric 6'-sulfated sialyl Lewis x.
Q42223600Eosinophils are not required for the induction and maintenance of an alloantibody response
Q51024387Eosinophils are required for the maintenance of plasma cells in the bone marrow.
Q38234940Eosinophils in the lung - modulating apoptosis and efferocytosis in airway inflammation.
Q52948211Eosinophils orchestrate cancer rejection by normalizing tumor vessels and enhancing infiltration of CD8(+) T cells.
Q35946412Expression and preliminary functional analysis of Siglec-F on mouse macrophages
Q47281057FACS isolation of live mouse eosinophils at high purity via a protocol that does not target Siglec F.
Q90061148Frontline Science: Superior mouse eosinophil depletion in vivo targeting transgenic Siglec-8 instead of endogenous Siglec-F: Mechanisms and pitfalls
Q24622257Galactose 6-O-sulfotransferases are not required for the generation of Siglec-F ligands in leukocytes or lung tissue
Q41207923Glycobiology of Eosinophilic Inflammation: Contributions of Siglecs, Glycans, and Other Glycan-Binding Proteins.
Q35898996Granulocyte Macrophage Colony-Stimulating Factor-Activated Eosinophils Promote Interleukin-23 Driven Chronic Colitis
Q34641855Human versus mouse eosinophils: "that which we call an eosinophil, by any other name would stain as red".
Q84698017IL-33 Exacerbates Eosinophil-Mediated Airway Inflammation
Q40146282IL-33 restricts tumor growth and inhibits pulmonary metastasis in melanoma-bearing mice through eosinophils.
Q36150043IL-33-Induced Cytokine Secretion and Survival of Mouse Eosinophils Is Promoted by Autocrine GM-CSF
Q52719869Identification of a Siglec-F+ granulocyte-macrophage progenitor.
Q52851663Isolation of Eosinophils from the Lamina Propria of the Murine Small Intestine.
Q38696593Leveraging Siglec-8 endocytic mechanisms to kill human eosinophils and malignant mast cells
Q28290873Mechanism of Siglec-8-mediated cell death in IL-5-activated eosinophils: role for reactive oxygen species-enhanced MEK/ERK activation
Q21132992Mechanisms of Siglec-F-induced eosinophil apoptosis: a role for caspases but not for SHP-1, Src kinases, NADPH oxidase or reactive oxygen
Q24624727Mice deficient in the St3gal3 gene product α2,3 sialyltransferase (ST3Gal-III) exhibit enhanced allergic eosinophilic airway inflammation
Q60305285Modulation of Immune Tolerance via Siglec-Sialic Acid Interactions
Q54324728Mouse Eosinophils: Identification, Isolation, and Functional Analysis.
Q35108579Non-invasive optical imaging of eosinophilia during the course of an experimental allergic airways disease model and in response to therapy.
Q34444620Novel targeted therapies for eosinophil-associated diseases and allergy
Q36763565Novel targeted therapies for eosinophilic disorders
Q38850676Paired Ig-like Receptor B Inhibits IL-13-Driven Eosinophil Accumulation and Activation in the Esophagus
Q52913728Phenotypic plasticity and targeting of Siglec-F(high) CD11c(low) eosinophils to the airway in a murine model of asthma.
Q34329191Polymorphisms in the sialic acid-binding immunoglobulin-like lectin-8 (Siglec-8) gene are associated with susceptibility to asthma
Q38676224Regulation of airway inflammation by Siglec-8 and Siglec-9 sialoglycan ligand expression
Q38256352Regulation of spontaneous eosinophil apoptosis-a neglected area of importance
Q35164415Role of siglecs and related glycan-binding proteins in immune responses and immunoregulation
Q92399549Sex differences in IL-17 contribute to chronicity in male versus female urinary tract infection
Q37983131Siglec-8 and Siglec-F, the new therapeutic targets in asthma
Q36655884Siglec-8 as a drugable target to treat eosinophil and mast cell-associated conditions
Q37343465Siglec-8 on human eosinophils and mast cells, and Siglec-F on murine eosinophils, are functionally related inhibitory receptors
Q37693833Siglec-F inhibition reduces esophageal eosinophilia and angiogenesis in a mouse model of eosinophilic esophagitis
Q33710652Siglec-F-dependent negative regulation of allergen-induced eosinophilia depends critically on the experimental model
Q34314957Siglec-mediated regulation of immune cell function in disease.
Q26992091Siglecs and immune regulation
Q37440061Siglecs as targets for therapy in immune-cell-mediated disease
Q38075409Targeting eosinophils in allergy, inflammation and beyond
Q90208339The emerging roles of eosinophils in mucosal homeostasis
Q35222976The role of lung epithelial ligands for Siglec-8 and Siglec-F in eosinophilic inflammation.
Q34485066The schistosome glutathione S-transferase P28GST, a unique helminth protein, prevents intestinal inflammation in experimental colitis through a Th2-type response with mucosal eosinophils
Q38598881Therapeutic Targeting of Siglecs using Antibody- and Glycan-Based Approaches.
Q38613170Tissue Remodeling in Chronic Eosinophilic Esophageal Inflammation: Parallels in Asthma and Therapeutic Perspectives
Q33987218What targeting eosinophils has taught us about their role in diseases

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