| scholarly article | Q13442814 |
| P2093 | author name string | Bruce S Bochner | |
| Sherry A Hudson | |||
| Esra Nutku-Bilir | |||
| P2860 | cites work | Identification of SAF-2, a novel siglec expressed on eosinophils, mast cells, and basophils | Q28138424 |
| Ligation of Siglec-8: a selective mechanism for induction of human eosinophil apoptosis | Q28212692 | ||
| Siglecs--the major subfamily of I-type lectins | Q28261393 | ||
| Mechanism of Siglec-8-induced human eosinophil apoptosis: role of caspases and mitochondrial injury | Q28271835 | ||
| Glycan array screening reveals a candidate ligand for Siglec-8 | Q28295084 | ||
| Breaking the mitochondrial barrier | Q34286380 | ||
| The eosinophil | Q34503956 | ||
| Two categories of mammalian galactose-binding receptors distinguished by glycan array profiling | Q35545703 | ||
| Verdict in the case of therapies versus eosinophils: the jury is still out. | Q35624876 | ||
| Siglecs in innate immunity | Q36162931 | ||
| Bax-induced cytochrome C release from mitochondria is independent of the permeability transition pore but highly dependent on Mg2+ ions | Q36255553 | ||
| Molecules involved in the regulation of eosinophil apoptosis | Q36342176 | ||
| Age-related impairment of GM-CSF-induced signalling in neutrophils: role of SHP-1 and SOCS proteins | Q36671840 | ||
| Role for Bcl-xL in delayed eosinophil apoptosis mediated by granulocyte-macrophage colony-stimulating factor and interleukin-5. | Q38335200 | ||
| The adenoviral E4orf6 protein induces atypical apoptosis in response to DNA damage. | Q40195606 | ||
| Characterization of galectin-9-induced death of Jurkat T cells | Q40196844 | ||
| Bcl-Xl- and Bax-alpha-mediated regulation of apoptosis of human neutrophils via caspase-3. | Q40958624 | ||
| Bax-induced caspase activation and apoptosis via cytochrome c release from mitochondria is inhibitable by Bcl-xL. | Q40980272 | ||
| Interleukin-5 inhibits translocation of Bax to the mitochondria, cytochrome c release, and activation of caspases in human eosinophils | Q43745326 | ||
| Eosinophils from asthmatics release IL-5 in an autocrine fashion to prevent apoptosis through upregulation of Bcl-2 expression | Q46612556 | ||
| The scaffolding adapter Gab2, via Shp-2, regulates kit-evoked mast cell proliferation by activating the Rac/JNK pathway | Q50336720 | ||
| Intravenous immunoglobulin preparations contain anti–Siglec-8 autoantibodies | Q61959765 | ||
| Altered adhesion molecule expression and endothelial cell activation accompany the recruitment of human granulocytes to the lung after segmental antigen challenge | Q67542329 | ||
| Induction of apoptosis in human eosinophils by anti-Fas antibody treatment in vitro | Q71704501 | ||
| P433 | issue | 1 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | cell biology | Q7141 |
| interleukins | Q194908 | ||
| apoptotic process | Q14599311 | ||
| human eosinophil | Q101405048 | ||
| P304 | page(s) | 121-4 | |
| P577 | publication date | 2008-01-01 | |
| P1433 | published in | American Journal of Respiratory Cell and Molecular Biology | Q4744268 |
| P1476 | title | Interleukin-5 priming of human eosinophils alters siglec-8 mediated apoptosis pathways | |
| P478 | volume | 38 |
| Q36843245 | "Siglec"ting the allergic response for therapeutic targeting |
| Q92547616 | AK002, a Humanized Sialic Acid-Binding Immunoglobulin-Like Lectin-8 Antibody that Induces Antibody-Dependent Cell-Mediated Cytotoxicity against Human Eosinophils and Inhibits Mast Cell-Mediated Anaphylaxis in Mice |
| Q52320351 | Airway glycomic and allergic inflammatory consequences resulting from keratan sulfate galactose 6-O-sulfotransferase (CHST1) deficiency. |
| Q37348437 | Basic and clinical immunology of Siglecs |
| Q37986851 | CD33-related siglecs as potential modulators of inflammatory responses |
| Q89027053 | Characterization of Siglec-8 Expression on Lavage Cells after Segmental Lung Allergen Challenge |
| Q52619414 | Characterization of a novel mouse strain expressing human Siglec-8 only on eosinophils. |
| Q24608549 | Characterization of expression of glycan ligands for Siglec-F in normal mouse lungs |
| Q39627809 | Chemoattractant-Induced Signaling via the Ras–ERK and PI3K–Akt Networks, along with Leukotriene C4 Release, Is Dependent on the Tyrosine Kinase Lyn in IL-5– and IL-3–Primed Human Blood Eosinophils |
| Q24634555 | Developmental, malignancy-related, and cross-species analysis of eosinophil, mast cell, and basophil siglec-8 expression |
| Q35979630 | Electroacupuncture Attenuates Ovalbumin-Induced Allergic Asthma via Modulating CD4(+)CD25(+) Regulatory T Cells |
| Q45287479 | Enhancement of Siglec-8 expression predicts adverse prognosis in patients with clear cell renal cell carcinoma |
| Q33758139 | Eosinophil survival and apoptosis in health and disease |
| Q38353914 | Eosinophil-selective binding and proapoptotic effect in vitro of a synthetic Siglec-8 ligand, polymeric 6'-sulfated sialyl Lewis x. |
| Q34630341 | Eosinophils: multifaceted biological properties and roles in health and disease |
| Q35165332 | Expression of ligands for Siglec-8 and Siglec-9 in human airways and airway cells |
| Q41207923 | Glycobiology of Eosinophilic Inflammation: Contributions of Siglecs, Glycans, and Other Glycan-Binding Proteins. |
| Q37111287 | Glycobiology simplified: diverse roles of glycan recognition in inflammation |
| Q50068947 | Human eosinophils and mast cells: Birds of a feather flock together |
| Q24631401 | IL-33 enhances Siglec-8 mediated apoptosis of human eosinophils |
| Q42371492 | Lyn mediates FIP1L1-PDGFRA signal pathway facilitating IL-5RA intracellular signal through FIP1L1-PDGFRA/JAK2/Lyn/Akt network complex in CEL. |
| Q28290873 | Mechanism of Siglec-8-mediated cell death in IL-5-activated eosinophils: role for reactive oxygen species-enhanced MEK/ERK activation |
| Q21132992 | Mechanisms of Siglec-F-induced eosinophil apoptosis: a role for caspases but not for SHP-1, Src kinases, NADPH oxidase or reactive oxygen |
| Q24624727 | Mice deficient in the St3gal3 gene product α2,3 sialyltransferase (ST3Gal-III) exhibit enhanced allergic eosinophilic airway inflammation |
| Q34329191 | Polymorphisms in the sialic acid-binding immunoglobulin-like lectin-8 (Siglec-8) gene are associated with susceptibility to asthma |
| Q46484443 | Regulation of Siglec-8-induced intracellular reactive oxygen species production and eosinophil cell death by Src family kinases |
| Q38676224 | Regulation of airway inflammation by Siglec-8 and Siglec-9 sialoglycan ligand expression |
| Q35164415 | Role of siglecs and related glycan-binding proteins in immune responses and immunoregulation |
| Q46309701 | Sialic acid-binding immunoglobulin-like lectin 8 (Siglec-8) is an activating receptor mediating β2-integrin-dependent function in human eosinophils |
| Q89165774 | Sialylated keratan sulfate proteoglycans are Siglec-8 ligands in human airways |
| Q38860125 | Siglec-8 and Siglec-9 binding specificities and endogenous airway ligand distributions and properties |
| Q37983131 | Siglec-8 and Siglec-F, the new therapeutic targets in asthma |
| Q36655884 | Siglec-8 as a drugable target to treat eosinophil and mast cell-associated conditions |
| Q37343465 | Siglec-8 on human eosinophils and mast cells, and Siglec-F on murine eosinophils, are functionally related inhibitory receptors |
| Q24651513 | Siglec-F antibody administration to mice selectively reduces blood and tissue eosinophils |
| Q37693833 | Siglec-F inhibition reduces esophageal eosinophilia and angiogenesis in a mouse model of eosinophilic esophagitis |
| Q33710652 | Siglec-F-dependent negative regulation of allergen-induced eosinophilia depends critically on the experimental model |
| Q34314957 | Siglec-mediated regulation of immune cell function in disease. |
| Q37126813 | Structural basis for sulfation-dependent self-glycan recognition by the human immune-inhibitory receptor Siglec-8 |
| Q35222976 | The role of lung epithelial ligands for Siglec-8 and Siglec-F in eosinophilic inflammation. |
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