Regulation of Siglec-8-induced intracellular reactive oxygen species production and eosinophil cell death by Src family kinases

scientific article published on 20 September 2016

Regulation of Siglec-8-induced intracellular reactive oxygen species production and eosinophil cell death by Src family kinases is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.IMBIO.2016.09.006
P932PMC publication ID5154890
P698PubMed publication ID27682013

P50authorBruce S. BochnerQ50069005
P2093author name stringNives Zimmermann
Gen Kano
P2860cites workChronic OVA allergen challenged Siglec-F deficient mice have increased mucus, remodeling, and epithelial Siglec-F ligands which are up-regulated by IL-4 and IL-13Q21284418
Siglec-8. A novel eosinophil-specific member of the immunoglobulin superfamilyQ22011026
Mice deficient in the St3gal3 gene product α2,3 sialyltransferase (ST3Gal-III) exhibit enhanced allergic eosinophilic airway inflammationQ24624727
How mitochondria produce reactive oxygen speciesQ24643882
Defining the in vivo function of Siglec-F, a CD33-related Siglec expressed on mouse eosinophilsQ24678441
Interleukin-5 priming of human eosinophils alters siglec-8 mediated apoptosis pathwaysQ24685595
Identification of SAF-2, a novel siglec expressed on eosinophils, mast cells, and basophilsQ28138424
Ligation of Siglec-8: a selective mechanism for induction of human eosinophil apoptosisQ28212692
CD22 regulates B cell receptor-mediated signals via two domains that independently recruit Grb2 and SHP-1Q28215970
Inhibition of FcepsilonRI-dependent mediator release and calcium flux from human mast cells by sialic acid-binding immunoglobulin-like lectin 8 engagementQ28258592
Mechanism of Siglec-8-induced human eosinophil apoptosis: role of caspases and mitochondrial injuryQ28271835
Mechanism of Siglec-8-mediated cell death in IL-5-activated eosinophils: role for reactive oxygen species-enhanced MEK/ERK activationQ28290873
cIAP1 and TAK1 protect cells from TNF-induced necrosis by preventing RIP1/RIP3-dependent reactive oxygen species productionQ28591258
Eosinophil extracellular DNA trap cell death mediates lytic release of free secretion-competent eosinophil granules in humans.Q30537562
Siglec-mediated regulation of immune cell function in disease.Q34314957
Polymorphisms in the sialic acid-binding immunoglobulin-like lectin-8 (Siglec-8) gene are associated with susceptibility to asthmaQ34329191
Negative regulation of immunoreceptor signalingQ34542282
ROS-triggered phosphorylation of complex II by Fgr kinase regulates cellular adaptation to fuel useQ34762124
Role of siglecs and related glycan-binding proteins in immune responses and immunoregulationQ35164415
Endogenous airway mucins carry glycans that bind Siglec-F and induce eosinophil apoptosis.Q35612914
Siglec-8 as a drugable target to treat eosinophil and mast cell-associated conditionsQ36655884
Multiple roles of Lyn kinase in myeloid cell signaling and functionQ37416257
Intracellular generation of superoxide by the phagocyte NADPH oxidase: how, where, and what for?Q37792519
Eosinophil-selective binding and proapoptotic effect in vitro of a synthetic Siglec-8 ligand, polymeric 6'-sulfated sialyl Lewis x.Q38353914
Eosinophils oxidize damage-associated molecular pattern molecules derived from stressed cellsQ39793141
Cellular defenses against damage from reactive oxygen speciesQ40808542
Myeloid specific human CD33 is an inhibitory receptor with differential ITIM function in recruiting the phosphatases SHP-1 and SHP-2.Q40869447
Immunoreceptor tyrosine-based inhibitory motif (ITIM)-mediated inhibitory signaling is regulated by sequential phosphorylation mediated by distinct nonreceptor tyrosine kinases: a case study involving PECAM-1Q41137784
Regulation of B cell functions by the sialic acid-binding receptors siglec-G and CD22.Q42144247
Class I phosphoinositide-3-kinases and SRC kinases play a nonredundant role in regulation of adhesion-independent and -dependent neutrophil reactive oxygen species generationQ43085735
The induction of eosinophil peroxidase release: improved methods of measurement and stimulationQ45042220
Autophosphorylation of Src and Yes blocks their inactivation by Csk phosphorylationQ77483301
P433issue2
P921main subjectreactive oxygen speciesQ424361
P304page(s)343-349
P577publication date2016-09-20
P1433published inImmunobiologyQ15754985
P1476titleRegulation of Siglec-8-induced intracellular reactive oxygen species production and eosinophil cell death by Src family kinases
P478volume222

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cites work (P2860)
Q89027053Characterization of Siglec-8 Expression on Lavage Cells after Segmental Lung Allergen Challenge
Q41207923Glycobiology of Eosinophilic Inflammation: Contributions of Siglecs, Glycans, and Other Glycan-Binding Proteins.
Q40116200Recent advances in understanding eosinophil biology
Q46309701Sialic acid-binding immunoglobulin-like lectin 8 (Siglec-8) is an activating receptor mediating β2-integrin-dependent function in human eosinophils

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