Characterization of Siglec-8 Expression on Lavage Cells after Segmental Lung Allergen Challenge

scientific article published on 07 June 2018

Characterization of Siglec-8 Expression on Lavage Cells after Segmental Lung Allergen Challenge is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1159/000488951
P932PMC publication ID6105496
P698PubMed publication ID29879704

P50authorNizar N JarjourQ88330675
P2093author name stringBruce S Bochner
Elizabeth A Kelly
Mats W Johansson
Christopher L Nguyen
P2860cites workRegulation of Eosinophil Recruitment and Activation by Galectins in Allergic AsthmaQ39377433
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Regulation of Eosinophil and Group 2 Innate Lymphoid Cell Trafficking in AsthmaQ41370706
Dissection of the hyperadhesive phenotype of airway eosinophils in asthmaQ41975092
Mepolizumab for prednisone-dependent asthma with sputum eosinophiliaQ46098864
Sialic acid-binding immunoglobulin-like lectin 8 (Siglec-8) is an activating receptor mediating β2-integrin-dependent function in human eosinophilsQ46309701
Regulation of Siglec-8-induced intracellular reactive oxygen species production and eosinophil cell death by Src family kinasesQ46484443
Mepolizumab Attenuates Airway Eosinophil Numbers, but Not Their Functional Phenotype, in Asthma.Q47786031
IL-3 up-regulates and activates human eosinophil CD32 and αMβ2 integrin causing degranulation.Q48014771
IL-5-stimulated eosinophils adherent to periostin undergo stereotypic morphological changes and ADAM8-dependent migrationQ48318859
Identification of IgE-bearing cells in the late-phase response to antigen in the lung as basophils.Q50774303
Eosinophil's role remains uncertain as anti-interleukin-5 only partially depletes numbers in asthmatic airway.Q51699174
Immunophenotypic study of basophils by multiparameter flow cytometryQ81240091
Eosinophil beta 1 integrin activation state correlates with asthma activity in a blind study of inhaled corticosteroid withdrawalQ83917010
IL-33 enhances Siglec-8 mediated apoptosis of human eosinophilsQ24631401
Interleukin-5 priming of human eosinophils alters siglec-8 mediated apoptosis pathwaysQ24685595
Identification of SAF-2, a novel siglec expressed on eosinophils, mast cells, and basophilsQ28138424
Ligation of Siglec-8: a selective mechanism for induction of human eosinophil apoptosisQ28212692
Decreased expression of membrane IL-5 receptor alpha on human eosinophils: I. Loss of membrane IL-5 receptor alpha on airway eosinophils and increased soluble IL-5 receptor alpha in the airway after allergen challengeQ28215560
Eosinophil Activation Status in Separate Compartments and Association with AsthmaQ33785627
IL-5 induces suspended eosinophils to undergo unique global reorganization associated with primingQ33799642
A role for eosinophils in airway remodelling in asthmaQ34550355
Safety of and cellular response to segmental bronchoprovocation in allergic asthmaQ34558188
Eosinophils: changing perspectives in health and diseaseQ35170969
Activation of beta1 integrins on blood eosinophils by P-selectinQ35528037
Endogenous airway mucins carry glycans that bind Siglec-F and induce eosinophil apoptosis.Q35612914
Platelet activation, P-selectin, and eosinophil β1-integrin activation in asthmaQ35813671
Expression and preliminary functional analysis of Siglec-F on mouse macrophagesQ35946412
Flow Cytometric Analysis of Myeloid Cells in Human Blood, Bronchoalveolar Lavage, and Lung TissuesQ36549074
Anti-IL-5 attenuates activation and surface density of β(2) -integrins on circulating eosinophils after segmental antigen challenge.Q36630280
"Siglec"ting the allergic response for therapeutic targetingQ36843245
Up-regulation and activation of eosinophil integrins in blood and airway after segmental lung antigen challengeQ36980346
Mepolizumab and exacerbations of refractory eosinophilic asthmaQ37711391
Tissue Remodeling in Chronic Eosinophilic Esophageal Inflammation: Parallels in Asthma and Therapeutic PerspectivesQ38613170
Leveraging Siglec-8 endocytic mechanisms to kill human eosinophils and malignant mast cellsQ38696593
P4510describes a project that usesImageJQ1659584
P433issue1
P304page(s)16-28
P577publication date2018-06-07
P1433published inInternational Archives of Allergy and ImmunologyQ2189251
P1476titleCharacterization of Siglec-8 Expression on Lavage Cells after Segmental Lung Allergen Challenge
P478volume177

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cites work (P2860)
Q98237564A FACS-based approach to obtain viable eosinophils from human adipose tissue
Q92547616AK002, a Humanized Sialic Acid-Binding Immunoglobulin-Like Lectin-8 Antibody that Induces Antibody-Dependent Cell-Mediated Cytotoxicity against Human Eosinophils and Inhibits Mast Cell-Mediated Anaphylaxis in Mice
Q60939538Mast Cell-Specific Expression of Human Siglec-8 in Conditional Knock-in Mice
Q60305285Modulation of Immune Tolerance via Siglec-Sialic Acid Interactions

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