HIV-1 nuclear import: matrix protein is back on center stage, this time together with Vpr

scientific article

HIV-1 nuclear import: matrix protein is back on center stage, this time together with Vpr is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P932PMC publication ID2230352
P698PubMed publication ID9562972

P2093author name stringM I Bukrinsky
O K Haffar
P2860cites workIdentification of NTF2, a cytosolic factor for nuclear import that interacts with nuclear pore complex protein p62Q24317417
Two different subunits of importin cooperate to recognize nuclear localization signals and bind them to the nuclear envelopeQ24320769
Viral protein R regulates nuclear import of the HIV-1 pre-integration complexQ24533072
Human major HSP70 protein complements the localization and functional defects of cytoplasmic mutant SV40 T antigen in Swiss 3T3 mouse fibroblast cellsQ42825476
Importin provides a link between nuclear protein import and U snRNA exportQ48059143
Role of the nuclear transport factor p10 in nuclear importQ48064951
The nuclear pore‐targeting complex binds to nuclear pores after association with a karyophileQ48072038
Biochemical mechanism of HIV-1 Vpr function. Oligomerization mediated by the N-terminal domain.Q54188872
Assembly of the Preprotein Receptor MOM72/MAS70 into the Protein Import Complex of the Outer Membrane of MitochondriaQ63026756
70-kDa heat-shock cognate protein colocalizes with karyophilic proteins into the nucleus during their transport in vitroQ70680886
Infant-maternal HIV-specific immunoglobulin G1 antibody ratios as an indicator of vertical transmissionQ73535496
Identification of different roles for RanGDP and RanGTP in nuclear protein importQ24561933
Active nuclear import of human immunodeficiency virus type 1 preintegration complexesQ24564507
The Vpr protein of human immunodeficiency virus type 1 influences nuclear localization of viral nucleic acids in nondividing host cellsQ24564509
The nuclear localization signal of the matrix protein of human immunodeficiency virus type 1 allows the establishment of infection in macrophages and quiescent T lymphocytesQ24564711
Critical role of reverse transcriptase in the inhibitory mechanism of CNI-H0294 on HIV-1 nuclear translocationQ24603577
HIV-1 Vpr interacts with the nuclear transport pathway to promote macrophage infectionQ24608690
HIV-1 infection of nondividing cells through the recognition of integrase by the importin/karyopherin pathwayQ24642513
Role of the basic domain of human immunodeficiency virus type 1 matrix in macrophage infectionQ24673913
Role of the karyopherin pathway in human immunodeficiency virus type 1 nuclear importQ24684268
Mutational analysis of cell cycle arrest, nuclear localization and virion packaging of human immunodeficiency virus type 1 VprQ24684633
Crystal structures of the trimeric human immunodeficiency virus type 1 matrix protein: implications for membrane association and assemblyQ27732646
Nuclear targeting sequences--a consensus?Q27860997
Identification of a yeast karyopherin heterodimer that targets import substrate to mammalian nuclear pore complexesQ27934056
Protein import into nuclei: association and dissociation reactions involving transport substrate, transport factors, and nucleoporinsQ28131733
A nuclear localization signal within HIV-1 matrix protein that governs infection of non-dividing cellsQ28249434
HIV-1 entry into quiescent primary lymphocytes: molecular analysis reveals a labile, latent viral structureQ28283258
The glucocorticoid receptor type II complex is a target of the HIV-1 vpr gene productQ28368083
Multiply attenuated lentiviral vector achieves efficient gene delivery in vivoQ29616612
The GTP-binding protein Ran/TC4 is required for protein import into the nucleusQ29620192
Inhibition of nuclear protein import by nonhydrolyzable analogues of GTP and identification of the small GTPase Ran/TC4 as an essential transport factorQ29620193
Cytosolic proteins that specifically bind nuclear location signals are receptors for nuclear importQ29620195
Purification of a Ran-interacting protein that is required for protein import into the nucleusQ29620570
HIV-1 infection of non-dividing cells: evidence that the amino-terminal basic region of the viral matrix protein is important for Gag processing but not for post-entry nuclear import.Q33887160
Integration of murine leukemia virus DNA depends on mitosisQ34051046
Biochemical mechanism of HIV-I Vpr function. Specific interaction with a cellular protein.Q34341976
Nuclear protein importQ34426767
Subcellular localization of avian sarcoma virus and human immunodeficiency virus type 1 integrasesQ35876147
Nuclear import, virion incorporation, and cell cycle arrest/differentiation are mediated by distinct functional domains of human immunodeficiency virus type 1 Vpr.Q35890940
Highly efficient and sustained gene transfer in adult neurons with a lentivirus vector.Q35891440
The effects of variations in the number and sequence of targeting signals on nuclear uptakeQ36219342
RanBP1 stabilizes the interaction of Ran with p97 nuclear protein importQ36237637
Integration is not necessary for expression of human immunodeficiency virus type 1 protein productsQ36806287
The transport of proteins into the nucleus requires the 70-kilodalton heat shock protein or its cytosolic cognateQ36815000
Passage through mitosis is required for oncoretroviruses but not for the human immunodeficiency virusQ40037960
Human immunodeficiency virus type 1 DNA synthesis, integration, and efficient viral replication in growth-arrested T cells.Q40045880
Differential expression and sequence-specific interaction of karyopherin alpha with nuclear localization sequencesQ41127829
In vivo nuclear transport kinetics in Saccharomyces cerevisiae: a role for heat shock protein 70 during targeting and translocationQ42772500
P433issue3
P407language of work or nameEnglishQ1860
P304page(s)138-43
P577publication date1998-03-01
P1433published inMolecular MedicineQ6895961
P1476titleHIV-1 nuclear import: matrix protein is back on center stage, this time together with Vpr
P478volume4

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cites work (P2860)
Q40624947Assessment of the role of the central DNA flap in human immunodeficiency virus type 1 replication by using a single-cycle replication system
Q22010464Cloning and characterization of hIF2, a human homologue of bacterial translation initiation factor 2, and its interaction with HIV-1 matrix
Q33883977Equine infectious anemia virus Gag p9 function in early steps of virus infection and provirus production
Q36368186Expression of the c-myc proto-oncogene is essential for HIV-1 infection in activated T cells.
Q28478027Nuclear exportin receptor CAS regulates the NPI-1-mediated nuclear import of HIV-1 Vpr
Q39594236Oligomerization within virions and subcellular localization of human immunodeficiency virus type 1 integrase
Q35980749Quantitative proteomic analysis of HIV-1 infected CD4+ T cells reveals an early host response in important biological pathways: protein synthesis, cell proliferation, and T-cell activation.
Q38003158The HIV-1 passage from cytoplasm to nucleus: the process involving a complex exchange between the components of HIV-1 and cellular machinery to access nucleus and successful integration.
Q21245211The Vpr protein from HIV-1: distinct roles along the viral life cycle
Q39592447The karyophilic properties of human immunodeficiency virus type 1 integrase are not required for nuclear import of proviral DNA.

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