Disrupting antibiotic resistance propagation by inhibiting the conjugative DNA relaxase

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Disrupting antibiotic resistance propagation by inhibiting the conjugative DNA relaxase is …
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scholarly articleQ13442814

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P819ADS bibcode2007PNAS..10412282L
P356DOI10.1073/PNAS.0702760104
P3181OpenCitations bibliographic resource ID2968758
P932PMC publication ID1916486
P698PubMed publication ID17630285
P5875ResearchGate publication ID6208507

P50authorScott A LujanQ80609547
Matthew R RedinboQ87113704
P2093author name stringLaura M Guogas
Steven W Matson
Heather Ragonese
P2860cites workStructural Insights into Single-Stranded DNA Binding and Cleavage by F Factor TraIQ27642498
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F plasmid conjugative DNA transfer: the TraI helicase activity is essential for DNA strand transferQ73130846
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The mechanism of plasmid curing in bacteriaQ36536551
Concerted action of three distinct domains in the DNA cleaving-joining reaction catalyzed by relaxase (TraI) of conjugative plasmid RP4.Q38311809
Unveiling the molecular mechanism of a conjugative relaxase: The structure of TrwC complexed with a 27-mer DNA comprising the recognition hairpin and the cleavage site.Q38314980
Two active-site tyrosyl residues of protein TrwC act sequentially at the origin of transfer during plasmid R388 conjugationQ38315911
Site-specific nicking in vitro at ori T by the DNA relaxase of Tn5252.Q38350000
Mechanisms of initiation and termination reactions in conjugative DNA processing. Independence of tight substrate binding and catalytic activity of relaxase (TraI) of IncPalpha plasmid RP4.Q38357475
NikAB- or NikB-dependent intracellular recombination between tandemly repeated oriT sequences of plasmid R64 in plasmid or single-stranded phage vectorsQ39775222
Inhibition of R-plasmid transfer in Escherichia coli by 4-quinolonesQ39827963
Conjugation-independent, site-specific recombination at the oriT of the IncW plasmid R388 mediated by TrwC.Q39932074
Nucleotide sequence and functions of the oriT operon in IncI1 plasmid R64Q39941075
Technetium-99m labelled imidodiphosphate: an improved bone-scanning radiopharmaceuticalQ39994327
In vitrocleavage of double- and single-stranded DNA by plasmid RSF1010-encoded mobilization proteinsQ40411335
Novel fluorescent technology platform for high throughput cytotoxicity and proliferation assaysQ40868499
Inhibition of conjugal transfer of R plasmids by pipemidic acid and related compoundsQ40947651
Enzymology of DNA transfer by conjugative mechanismsQ41080217
Endonuclease activity of Escherichia coli DNA helicase I directed against the transfer origin of the F factor.Q41082261
Nicking by transesterification: the reaction catalysed by a relaxaseQ41627061
Genetic organization of the conjugal DNA processing region of the IncW plasmid R388.Q42611720
Complete sequence of the IncP-9 TOL plasmid pWW0 from Pseudomonas putidaQ42692935
Escherichia coli DNA helicase I catalyzes a site- and strand-specific nicking reaction at the F plasmid oriTQ44108270
The absolute bioavailability of clodronate from two different oral dosesQ44136623
Genomic analysis of a multidrug-resistant strain of enterohaemorrhagic Escherichia coli O157:H7 causing a family outbreak in Japan.Q46642961
Nosocomial spread of multi-resistant Klebsiella pneumoniae containing a plasmid encoding multiple beta-lactamasesQ46642963
Comparison of technetium-99m pyrophosphate and technetium-99m methylene diphosphonate with variable amounts of stannous chloride in the detection of acute myocardial infarctionQ49300165
Carica papaya seed macerate as inhibitor of conjugative R plasmid transfer from Salmonella typhimurium to Escherichia coli in vitro and in the digestive tract of gnotobiotic miceQ50091257
Intestinal absorption of disodium ethane-1-hydroxy-1,1-diphosphonate (disodium etidronate) using a deconvolution technique.Q52947776
Covalent association of the traI gene product of plasmid RP4 with the 5'-terminal nucleotide at the relaxation nick site.Q53033546
Inhibition of conjugal transfer of R plasmids by nitrofurans.Q54445173
Effect of bambermycins, in vitro, on plasmid-mediated antimicrobial resistanceQ54466510
Conjugative DNA synthesis: R1162 and the question of rolling-circle replication.Q54534213
Structure-function analysis of Escherichia coli DNA helicase I reveals non-overlapping transesterase and helicase domains.Q54538025
Inhibition of F'lac transfer by various antibacterial drugs in Escherichia coli.Q54644387
Escherichia coli DNA helicase I catalyzes a unidirectional and highly processive unwinding reaction.Q54751630
Effect of subinhibitory concentrations of ampicillin on the R plasmid transfer in Escherichia coli.Q54762804
Inhibition of conjugal transfer by new quinolinic compounds.Q54797008
The effects of cannabispiro compounds and tetrahydrocannabidiolic acid on the plasmid transfer and maintenance in Escherichia coliQ68947904
Evidence that DNA helicase I and oriT site-specific nicking are both functions of the F TraI proteinQ69847405
Hydrolysis of adenyl-5-yl imidodiphosphate by beef heart mitochondrial ATPaseQ69875842
P433issue30
P407language of work or nameEnglishQ1860
P921main subjectantibiotic resistanceQ380775
P304page(s)12282-12287
P577publication date2007-07-13
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleDisrupting antibiotic resistance propagation by inhibiting the conjugative DNA relaxase
P478volume104

Reverse relations

cites work (P2860)
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