scholarly article | Q13442814 |
P50 | author | Daniel Pipeleers | Q64358610 |
P2093 | author name string | Gerard Gradwohl | |
Harry Heimberg | |||
Palle Serup | |||
Ole Madsen | |||
Yves Heremans | |||
Mark Van De Casteele | |||
Peter in't Veld | |||
P2860 | cites work | neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas | Q24647944 |
A simplified system for generating recombinant adenoviruses | Q24682328 | ||
Notch signaling: cell fate control and signal integration in development | Q27861061 | ||
Human and rat beta cells differ in glucose transporter but not in glucokinase gene expression | Q27865298 | ||
Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen | Q28141785 | ||
Autoregulation and maturity onset diabetes of the young transcription factors control the human PAX4 promoter | Q28145110 | ||
Notch signalling controls pancreatic cell differentiation | Q28504686 | ||
Paired-homeodomain transcription factor PAX4 acts as a transcriptional repressor in early pancreatic development | Q28504907 | ||
Control of endodermal endocrine development by Hes-1 | Q28513574 | ||
Modulation of rat pancreatic acinoductal transdifferentiation and expression of PDX-1 in vitro | Q28578821 | ||
Independent development of pancreatic alpha- and beta-cells from neurogenin3-expressing precursors: a role for the notch pathway in repression of premature differentiation | Q28594048 | ||
Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors | Q29619012 | ||
Biosynthesis of the prohormone convertase mPC1 in AtT-20 cells | Q30921107 | ||
Pancreas: how to get there from the gut? | Q33796338 | ||
Differentiation of embryonic stem cells to insulin-secreting structures similar to pancreatic islets. | Q33944464 | ||
Regulation of the pancreatic islet-specific gene BETA2 (neuroD) by neurogenin 3. | Q33963287 | ||
Transdifferentiation and metaplasia--switching cell types | Q34353179 | ||
Factors controlling pancreatic cell differentiation and function. | Q34398818 | ||
In vitro cultivation of human islets from expanded ductal tissue | Q35174217 | ||
The glucose sensor protein glucokinase is expressed in glucagon-producing alpha-cells | Q37483658 | ||
Key events of pancreas formation are triggered in gut endoderm by ectopic expression of pancreatic regulatory genes | Q40423677 | ||
Insulin production by human embryonic stem cells | Q40695005 | ||
Molecular basis of transdifferentiation of pancreas to liver | Q40833571 | ||
Expression of neurogenin3 reveals an islet cell precursor population in the pancreas | Q40867538 | ||
Pax4 represses pancreatic glucagon gene expression | Q40868934 | ||
Attenuation of green fluorescent protein half-life in mammalian cells | Q40909794 | ||
Expression of neuronal traits in pancreatic beta cells. Implication of neuron-restrictive silencing factor/repressor element silencing transcription factor, a neuron-restrictive silencer. | Q41133907 | ||
Diversity and pattern in the developing spinal cord | Q41191457 | ||
The beta cell transcription factors and development of the pancreas | Q41496269 | ||
Homeobox gene Nkx6.1 lies downstream of Nkx2.2 in the major pathway of beta-cell formation in the pancreas. | Q43408666 | ||
Ablation of insulin-producing neurons in flies: growth and diabetic phenotypes | Q43988822 | ||
Cationic liposomes enhance adenovirus entry via a pathway independent of the fiber receptor and alpha(v)-integrins | Q46216148 | ||
Extra-insular beta cells associated with ductules are frequent in adult human pancreas | Q47854299 | ||
Homeobox gene product Nkx 6.1 immunoreactivity in nuclei of endocrine cells of rat and mouse stomach | Q48035174 | ||
Insulin is released from rat brain neuronal cells in culture | Q48305708 | ||
Implantation of standardized beta-cell grafts in a liver segment of IDDM patients: graft and recipients characteristics in two cases of insulin-independence under maintenance immunosuppression for prior kidney graft. | Q51570519 | ||
The Notch ligand, X-Delta-2, mediates segmentation of the paraxial mesoderm in Xenopus embryos. | Q52195971 | ||
The Pax4 gene is essential for differentiation of insulin-producing β cells in the mammalian pancreas | Q59069706 | ||
Inhibition of cytokine-induced NF-kappaB activation by adenovirus-mediated expression of a NF-kappaB super-repressor prevents beta-cell apoptosis | Q64379478 | ||
Cytokeratins as Markers of Ductal Cell Differentiation and Islet Neogenesis in the Neonatal Rat Pancreas | Q71650182 | ||
Developmental biology of the pancreas | Q71845371 | ||
Adult human pancreatic duct and islet cells exhibit similarities in expression and differences in phosphorylation and complex formation of the homeodomain protein Ipf-1 | Q73933782 | ||
P433 | issue | 2 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | cell biology | Q7141 |
P304 | page(s) | 303-12 | |
P577 | publication date | 2002-10-28 | |
P1433 | published in | Journal of Cell Biology | Q1524550 |
P1476 | title | Recapitulation of embryonic neuroendocrine differentiation in adult human pancreatic duct cells expressing neurogenin 3 | |
P478 | volume | 159 |
Q52714852 | (Re)generating Human Beta Cells: Status, Pitfalls, and Perspectives. |
Q30441221 | A feat of metabolic proportions: Pdx1 orchestrates islet development and function in the maintenance of glucose homeostasis |
Q34611802 | A mouse model for monitoring islet cell genesis and developing therapies for diabetes |
Q34460933 | Adenoviral vectors stimulate glucagon transcription in human mesenchymal stem cells expressing pancreatic transcription factors. |
Q35157499 | Alternative sources of beta cells for cell therapy of diabetes. |
Q46440920 | Association of childhood type 1 diabetes mellitus with a variant of PAX4: possible link to beta cell regenerative capacity |
Q33646501 | Beta Cell Formation in vivo Through Cellular Networking, Integration and Processing (CNIP) in Wild Type Adult Mice |
Q46853965 | Beta-cell differentiation from nonendocrine epithelial cells of the adult human pancreas. |
Q33395873 | Bipotential mouse embryonic liver (BMEL) cells spontaneously express Pdx1 and Ngn3 but do not undergo further pancreatic differentiation upon Hes1 down-regulation |
Q43096569 | CD45+/CD133+ positive cells expanded from umbilical cord blood expressing PDX-1 and markers of pluripotency |
Q35684842 | Cell therapies for type 1 diabetes mellitus |
Q37709553 | Cellular plasticity within the pancreas--lessons learned from development |
Q35934188 | Cellular sources of new pancreatic beta cells and therapeutic implications for regenerative medicine |
Q48331147 | Changes on the Pancreas in Experimental Diabetes and the Effect of Lycopene on These Changes: Pdx-1, Ngn-3, and Nestin Expressions. |
Q39687182 | Characterization of human pancreatic progenitor cells. |
Q58771324 | Characterization of induced tissue-specific stem cells from pancreas by a synthetic self-replicative RNA |
Q36935754 | Conserved role for the Drosophila Pax6 homolog Eyeless in differentiation and function of insulin-producing neurons. |
Q39138391 | Coxsackievirus B4 can infect human pancreas ductal cells and persist in ductal-like cell cultures which results in inhibition of Pdx1 expression and disturbed formation of islet-like cell aggregates. |
Q36523570 | Culture Conditions for Mouse Pancreatic Stem Cells |
Q28586023 | Dachshund homologues play a conserved role in islet cell development |
Q37326969 | Developmental biology of the pancreas: a comprehensive review |
Q37156679 | Diabetes mellitus: an opportunity for therapy with stem cells? |
Q37541907 | Differentiation of Mouse Pancreatic Stem Cells Into Insulin-Producing Cells by Recombinant Sendai Virus-Mediated Gene Transfer Technology |
Q40623131 | Discovery of Gene Networks Regulating Cytokine-Induced Dysfunction and Apoptosis in Insulin-Producing INS-1 Cells |
Q54693383 | EGF-induced proliferation of adult human pancreatic duct cells is mediated by the MEK/ERK cascade. |
Q36950245 | Early pancreatic islet fate and maturation is controlled through RBP-Jκ |
Q33869785 | Ectopic expression of E2F1 stimulates beta-cell proliferation and function. |
Q50728586 | Ectopic expression of neurogenin 3 in neonatal pig pancreatic precursor cells induces (trans)differentiation to functional alpha cells. |
Q43859421 | Efficient transfection of sendai virus vector to mouse pancreatic stem cells in the floating state. |
Q41913675 | Enriched human pancreatic ductal cultures obtained from selective death of acinar cells express pancreatic and duodenal homeobox gene-1 age-dependently |
Q82950558 | Epithelial cells within the human pancreas do not coexpress mesenchymal antigens: epithelial-mesenchymal transition is an artifact of cell culture |
Q39796077 | Establishment of mouse pancreatic stem cell line |
Q58744470 | Exome sequencing-based identification of novel type 2 diabetes risk allele loci in the Qatari population |
Q30416277 | Expansion and conversion of human pancreatic ductal cells into insulin-secreting endocrine cells |
Q38316969 | Expansion of mesenchymal stem cells from human pancreatic ductal epithelium |
Q53676084 | Expression of progenitor cell markers during expansion of sorted human pancreatic beta cells. |
Q37839897 | Facultative stem cells in liver and pancreas: fact and fancy. |
Q34286940 | Gene regulatory factors in pancreatic development |
Q36751590 | Gene therapy for type 1 diabetes: is it ready for the clinic? |
Q35841821 | Generation of surrogate beta cells from tissue stem cells |
Q79255376 | Global profiling of double stranded RNA- and IFN-?-induced genes in rat pancreatic beta cells |
Q37634920 | Growth Factor Independence-1 (Gfi1) Is Required for Pancreatic Acinar Unit Formation and Centroacinar Cell Differentiation |
Q35985310 | Harnessing the gut to treat diabetes |
Q28590347 | Hnf6 and Tcf2 (MODY5) are linked in a gene network operating in a precursor cell domain of the embryonic pancreas |
Q24306349 | IA1 is NGN3-dependent and essential for differentiation of the endocrine pancreas |
Q24338308 | Identification and differentiation of PDX1 β-cell progenitors within the human pancreatic epithelium |
Q38636706 | Identification of novel biomarkers to monitor β-cell function and enable early detection of type 2 diabetes risk. |
Q28509631 | Identification of the bHLH factor Math6 as a novel component of the embryonic pancreas transcriptional network |
Q57035930 | Immunohistochemical analysis of OTP and NKX6.1 in neuroendocrine tumors of the lung and pancreas |
Q24298172 | In vitro expression of NGN3 identifies RAB3B as the predominant Ras-associated GTP-binding protein 3 family member in human islets |
Q28292190 | In vivo reprogramming of adult pancreatic exocrine cells to beta-cells |
Q55389351 | Induced Tissue-Specific Stem Cells and Epigenetic Memory in Induced Pluripotent Stem Cells. |
Q64264355 | Induction of Expandable Tissue-Specific Progenitor Cells from Human Pancreatic Tissue through Transient Expression of Defined Factors |
Q40171133 | Induction of pancreatic stem/progenitor cells into insulin-producing cells by adenoviral-mediated gene transfer technology. |
Q34675268 | Induction of tissue-specific stem cells by reprogramming factors, and tissue-specific selection |
Q35028879 | Insulin but not glucagon gene is silenced in human pancreas-derived mesenchymal stem cells |
Q46678828 | Insulin-producing cells derived from human pancreatic non-endocrine cell cultures reverse streptozotocin-induced hyperglycaemia in mice |
Q33848224 | Insulinoma-associated antigen-1 zinc-finger transcription factor promotes pancreatic duct cell trans-differentiation |
Q41830502 | Intestinal Neurogenin 3 directs differentiation of a bipotential secretory progenitor to endocrine cell rather than goblet cell fate. |
Q52571161 | Islet hypertrophy following pancreatic disruption of Smad4 signaling. |
Q36523574 | Isolation Efficiency of Mouse Pancreatic Stem Cells Is Age Dependent |
Q43035117 | Isolation of genes involved in pancreas regeneration by subtractive hybridization. |
Q41281975 | Ligand-bound thyroid hormone receptor contributes to reprogramming of pancreatic acinar cells into insulin-producing cells |
Q89881041 | Long-term expansion, genomic stability and in vivo safety of adult human pancreas organoids |
Q34432947 | Loss of Fbw7 reprograms adult pancreatic ductal cells into α, δ, and β cells |
Q38951192 | Making β(-like)-cells from exocrine pancreas. |
Q51975119 | MicroRNA profiling of developing and regenerating pancreas reveal post-transcriptional regulation of neurogenin3. |
Q35546573 | Molecular development of the pancreatic β cell: implications for cell replacement therapy |
Q46428263 | Morphogenetic plasticity of adult human pancreatic islets of Langerhans |
Q42090137 | Multi-site Neurogenin3 Phosphorylation Controls Pancreatic Endocrine Differentiation. |
Q36000674 | NEUROG3 is a critical downstream effector for STAT3-regulated differentiation of mammalian stem and progenitor spermatogonia |
Q50287843 | NEUROG3-dependent synthesis of NEUROD1 |
Q50287844 | NEUROG3-dependent synthesis of NKX2-2 |
Q50287842 | NEUROG3-dependent synthesis of PAX4 protein |
Q24536173 | NeuroD1/E47 regulates the E-box element of a novel zinc finger transcription factor, IA-1, in developing nervous system |
Q34490166 | Neurogenin 3 Expressing Cells in the Human Exocrine Pancreas Have the Capacity for Endocrine Cell Fate |
Q37278665 | Neurogenin 3 is regulated by neurotrophic tyrosine kinase receptor type 2 (TRKB) signaling in the adult human exocrine pancreas |
Q36796789 | Neurogenin3 cooperates with Foxa2 to autoactivate its own expression. |
Q43136225 | Neurogenin3 is sufficient for transdetermination of hepatic progenitor cells into neo-islets in vivo but not transdifferentiation of hepatocytes |
Q58603205 | Neurogenin3 phosphorylation controls reprogramming efficiency of pancreatic ductal organoids into endocrine cells |
Q44930824 | New beta-cells from old acini |
Q28577625 | Ngn3 expression during postnatal in vitro beta cell neogenesis induced by the JAK/STAT pathway |
Q37662799 | Notch signaling in pancreatic endocrine cell and diabetes |
Q50539750 | Notch-mediated post-translational control of Ngn3 protein stability regulates pancreatic patterning and cell fate commitment. |
Q51717533 | Optimization and Scale-up Isolation and Culture of Neonatal Porcine Islets: Potential for Clinical Application. |
Q24314780 | Overexpression of the coactivator bridge-1 results in insulin deficiency and diabetes |
Q59092532 | Pancreas regeneration |
Q39356850 | Pancreatic differentiation of human dental pulp CD117⁺ stem cells |
Q34148810 | Pancreatic stem/progenitor cells for the treatment of diabetes. |
Q33346071 | Perplexing Pax: from puzzle to paradigm. |
Q37225110 | Phenotype reversion in fetal human liver epithelial cells identifies the role of an intermediate meso-endodermal stage before hepatic maturation |
Q34273843 | Plasticity of adult human pancreatic duct cells by neurogenin3-mediated reprogramming |
Q30448603 | Proendocrine genes coordinate the pancreatic islet differentiation program in vitro |
Q37878871 | Recent advances in stem cell research for the treatment of diabetes |
Q45381358 | Recombinant sendai virus-mediated gene transfer to mouse pancreatic stem cells. |
Q36267776 | Regulation of pancreatic beta-cell mass |
Q64904804 | Reprogramming Cells to Make Insulin. |
Q37139609 | Reprogramming adult human dermal fibroblasts to islet-like cells by epigenetic modification coupled to transcription factor modulation |
Q37629220 | Reprogramming into pancreatic endocrine cells based on developmental cues |
Q34452113 | Reprogramming of human pancreatic exocrine cells to β-like cells. |
Q34206308 | Revealing transcription factors during human pancreatic β cell development |
Q30420070 | Role of chromatin accessibility in the occupancy and transcription of the insulin gene by the pancreatic and duodenal homeobox factor 1. |
Q35035110 | Serum circulating microRNA profiling for identification of potential type 2 diabetes and obesity biomarkers |
Q36210472 | Significance of Notch1-signaling pathway in human pancreatic development and carcinogenesis |
Q37748390 | Small RNAs have a big impact on regeneration |
Q38800188 | Sources of beta cells inside the pancreas |
Q34972366 | Sox9: a master regulator of the pancreatic program |
Q37369660 | Stem Cells in the Treatment of Insulin-Dependent Diabetes Mellitus |
Q37696268 | Stem cell therapy for type 1 diabetes mellitus |
Q36309570 | Stem cells in the treatment of diabetes |
Q37305062 | Stem cells to pancreatic beta-cells: new sources for diabetes cell therapy |
Q35622965 | Stem cells: a promising source of pancreatic islets for transplantation in type 1 diabetes |
Q40245749 | Stimulation of cAMP signalling allows isolation of clonal pancreatic precursor cells from adult mouse pancreas. |
Q35061915 | Streptozotocin-induced expression of Ngn3 and Pax4 in neonatal rat pancreatic α-cells |
Q33865250 | Switching of mesodermal and endodermal properties in hTERT-modified and expanded fetal human pancreatic progenitor cells |
Q50421781 | Targeted Mutation of NGN3 Gene Disrupts Pancreatic Endocrine Cell Development in Pigs. |
Q38731193 | Targeting pancreatic expressed PAX genes for the treatment of diabetes mellitus and pancreatic neuroendocrine tumors. |
Q37724128 | The Diabetes-Linked Transcription Factor PAX4: From Gene to Functional Consequences |
Q35252235 | The Krüppel-like zinc finger protein GLIS3 transactivates neurogenin 3 for proper fetal pancreatic islet differentiation in mice. |
Q24675974 | The diabetes-linked transcription factor PAX4 promotes {beta}-cell proliferation and survival in rat and human islets |
Q36275668 | The molecular basis of transdifferentiation. |
Q38211528 | The regulation of pre- and post-maturational plasticity of mammalian islet cell mass. |
Q28567289 | The transcription factor PAX4 acts as a survival gene in INS-1E insulinoma cells |
Q38262028 | The use of β-cell transcription factors in engineering artificial β cells from non-pancreatic tissue |
Q50794436 | Towards the elucidation of the regulatory network guiding the insulin producing cells' differentiation. |
Q35857682 | Transcriptional networks controlling pancreatic development and beta cell function. |
Q34699211 | Transdifferentiation of pancreatic α-cells into insulin-secreting cells: From experimental models to underlying mechanisms |
Q35767225 | Transplantation: focus on kidney, liver and islet cells |
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Q42293235 | ptf1a+ , ela3l- cells are developmentally maintained progenitors for exocrine regeneration following extreme loss of acinar cells in zebrafish larvae |
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