Alleviation of 1,N6-ethanoadenine genotoxicity by the Escherichia coli adaptive response protein AlkB

scientific article

Alleviation of 1,N6-ethanoadenine genotoxicity by the Escherichia coli adaptive response protein AlkB is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2007PNAS..104..755F
P356DOI10.1073/PNAS.0607377104
P932PMC publication ID1783386
P698PubMed publication ID17213319
P5875ResearchGate publication ID6588719

P2093author name stringCatherine L Drennan
John M Essigmann
James C Delaney
Cintyu Wong
Lauren E Frick
P2860cites workDemethylation of 3-methylthymine in DNA by bacterial and human DNA dioxygenasesQ44989680
AlkB restores the biological function of mRNA and tRNA inactivated by chemical methylationQ45094529
Assays for determining lesion bypass efficiency and mutagenicity of site-specific DNA lesions in vivo.Q51174834
Formation of the cross-link 1-[N3-deoxycytidyl),2-[N1-deoxyguanosinyl]ethane in DNA treated with N,N'-bis(2-chloroethyl)-N-nitrosourea.Q54513973
Repair deficient mice reveal mABH2 as the primary oxidative demethylase for repairing 1meA and 3meC lesions in DNAQ24544017
Mutagenesis, genotoxicity, and repair of 1-methyladenine, 3-alkylcytosines, 1-methylguanine, and 3-methylthymine in alkB Escherichia coliQ24564125
The DNA-repair protein AlkB, EGL-9, and leprecan define new families of 2-oxoglutarate- and iron-dependent dioxygenasesQ24796635
Oxidative demethylation by Escherichia coli AlkB directly reverts DNA base damageQ28201532
AlkB reverses etheno DNA lesions caused by lipid oxidation in vitro and in vivoQ28275203
Crystal structures of catalytic complexes of the oxidative DNA/RNA repair enzyme AlkBQ28297760
Repair of methylation damage in DNA and RNA by mammalian AlkB homologuesQ28506420
Human and bacterial oxidative demethylases repair alkylation damage in both RNA and DNAQ29618091
AlkB-mediated oxidative demethylation reverses DNA damage in Escherichia coliQ29618092
AlkB mystery solved: oxidative demethylation of N1-methyladenine and N3-methylcytosine adducts by a direct reversal mechanism.Q30332381
Probing the active site tightness of DNA polymerase in subangstrom incrementsQ34115892
The AidB component of the Escherichia coli adaptive response to alkylating agents is a flavin-containing, DNA-binding proteinQ34233279
Structural insights by molecular dynamics simulations into differential repair efficiency for ethano-A versus etheno-A adducts by the human alkylpurine-DNA N-glycosylaseQ34376519
Reversal of DNA alkylation damage by two human dioxygenasesQ34429515
Recent progress on the Ada response for inducible repair of DNA alkylation damageQ35026363
DNA repair by bacterial AlkB proteins.Q35550854
Suppression of Escherichia coli alkB mutants by Saccharomyces cerevisiae genesQ35593508
Repairing DNA-methylation damageQ35709509
Alkylation damage in DNA and RNA--repair mechanisms and medical significanceQ35893368
Direct repair of the exocyclic DNA adduct 1,N6-ethenoadenine by the DNA repair AlkB proteinsQ36728833
Metabolism of the chloroethylnitrosoureasQ37508672
DNA alkylation by the haloethylnitrosoureas: nature of modifications produced and their enzymatic repair or removalQ37984292
Chloroethylnitrosourea-derived ethano cytosine and adenine adducts are substrates for Escherichia coli glycosylases excising analogous etheno adductsQ38337257
Substrate specificities of bacterial and human AlkB proteinsQ38339406
Minimal methylated substrate and extended substrate range of Escherichia coli AlkB protein, a 1-methyladenine-DNA dioxygenaseQ38351039
DNA adducts and DNA damage by antineoplastic and carcinogenic N-nitrosocompoundsQ39749041
Genotoxicity of 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU).Q40550919
Repair of 3-methylthymine and 1-methylguanine lesions by bacterial and human AlkB proteinsQ40637390
Synthesis of para-benzoquinone and 1,3-bis(2-chloroethyl)nitrosourea adducts and their incorporation into oligonucleotidesQ41712907
DNA polymerase catalysis in the absence of Watson-Crick hydrogen bonds: analysis by single-turnover kineticsQ42164113
Nature and biological significance of DNA modification by the haloethylnitrosoureasQ42218246
Formation of cyclic adducts in nucleic acids by the haloethylnitrosoureasQ42223206
In vivo hprt mutant frequencies in T-cells of normal human newbornsQ44107832
Miscoding properties of 1,N6-ethanoadenine, a DNA adduct derived from reaction with the antitumor agent 1,3-bis(2-chloroethyl)-1-nitrosoureaQ44668728
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectEscherichia coliQ25419
genotoxicityQ1009245
P304page(s)755-60
P577publication date2007-01-16
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleAlleviation of 1,N6-ethanoadenine genotoxicity by the Escherichia coli adaptive response protein AlkB
P478volume104

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cites work (P2860)
Q339082691,3-Butadiene-Induced Adenine DNA Adducts Are Genotoxic but Only Weakly Mutagenic When Replicated in Escherichia coli of Various Repair and Replication Backgrounds
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Q64985712DNA repair enzymes ALKBH2, ALKBH3, and AlkB oxidize 5-methylcytosine to 5-hydroxymethylcytosine, 5-formylcytosine and 5-carboxylcytosine in vitro.
Q36538528Electrochemical characterization of Escherichia coli adaptive response protein AidB
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