scholarly article | Q13442814 |
P819 | ADS bibcode | 2007PNAS..104..755F |
P356 | DOI | 10.1073/PNAS.0607377104 |
P932 | PMC publication ID | 1783386 |
P698 | PubMed publication ID | 17213319 |
P5875 | ResearchGate publication ID | 6588719 |
P2093 | author name string | Catherine L Drennan | |
John M Essigmann | |||
James C Delaney | |||
Cintyu Wong | |||
Lauren E Frick | |||
P2860 | cites work | Demethylation of 3-methylthymine in DNA by bacterial and human DNA dioxygenases | Q44989680 |
AlkB restores the biological function of mRNA and tRNA inactivated by chemical methylation | Q45094529 | ||
Assays for determining lesion bypass efficiency and mutagenicity of site-specific DNA lesions in vivo. | Q51174834 | ||
Formation of the cross-link 1-[N3-deoxycytidyl),2-[N1-deoxyguanosinyl]ethane in DNA treated with N,N'-bis(2-chloroethyl)-N-nitrosourea. | Q54513973 | ||
Repair deficient mice reveal mABH2 as the primary oxidative demethylase for repairing 1meA and 3meC lesions in DNA | Q24544017 | ||
Mutagenesis, genotoxicity, and repair of 1-methyladenine, 3-alkylcytosines, 1-methylguanine, and 3-methylthymine in alkB Escherichia coli | Q24564125 | ||
The DNA-repair protein AlkB, EGL-9, and leprecan define new families of 2-oxoglutarate- and iron-dependent dioxygenases | Q24796635 | ||
Oxidative demethylation by Escherichia coli AlkB directly reverts DNA base damage | Q28201532 | ||
AlkB reverses etheno DNA lesions caused by lipid oxidation in vitro and in vivo | Q28275203 | ||
Crystal structures of catalytic complexes of the oxidative DNA/RNA repair enzyme AlkB | Q28297760 | ||
Repair of methylation damage in DNA and RNA by mammalian AlkB homologues | Q28506420 | ||
Human and bacterial oxidative demethylases repair alkylation damage in both RNA and DNA | Q29618091 | ||
AlkB-mediated oxidative demethylation reverses DNA damage in Escherichia coli | Q29618092 | ||
AlkB mystery solved: oxidative demethylation of N1-methyladenine and N3-methylcytosine adducts by a direct reversal mechanism. | Q30332381 | ||
Probing the active site tightness of DNA polymerase in subangstrom increments | Q34115892 | ||
The AidB component of the Escherichia coli adaptive response to alkylating agents is a flavin-containing, DNA-binding protein | Q34233279 | ||
Structural insights by molecular dynamics simulations into differential repair efficiency for ethano-A versus etheno-A adducts by the human alkylpurine-DNA N-glycosylase | Q34376519 | ||
Reversal of DNA alkylation damage by two human dioxygenases | Q34429515 | ||
Recent progress on the Ada response for inducible repair of DNA alkylation damage | Q35026363 | ||
DNA repair by bacterial AlkB proteins. | Q35550854 | ||
Suppression of Escherichia coli alkB mutants by Saccharomyces cerevisiae genes | Q35593508 | ||
Repairing DNA-methylation damage | Q35709509 | ||
Alkylation damage in DNA and RNA--repair mechanisms and medical significance | Q35893368 | ||
Direct repair of the exocyclic DNA adduct 1,N6-ethenoadenine by the DNA repair AlkB proteins | Q36728833 | ||
Metabolism of the chloroethylnitrosoureas | Q37508672 | ||
DNA alkylation by the haloethylnitrosoureas: nature of modifications produced and their enzymatic repair or removal | Q37984292 | ||
Chloroethylnitrosourea-derived ethano cytosine and adenine adducts are substrates for Escherichia coli glycosylases excising analogous etheno adducts | Q38337257 | ||
Substrate specificities of bacterial and human AlkB proteins | Q38339406 | ||
Minimal methylated substrate and extended substrate range of Escherichia coli AlkB protein, a 1-methyladenine-DNA dioxygenase | Q38351039 | ||
DNA adducts and DNA damage by antineoplastic and carcinogenic N-nitrosocompounds | Q39749041 | ||
Genotoxicity of 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU). | Q40550919 | ||
Repair of 3-methylthymine and 1-methylguanine lesions by bacterial and human AlkB proteins | Q40637390 | ||
Synthesis of para-benzoquinone and 1,3-bis(2-chloroethyl)nitrosourea adducts and their incorporation into oligonucleotides | Q41712907 | ||
DNA polymerase catalysis in the absence of Watson-Crick hydrogen bonds: analysis by single-turnover kinetics | Q42164113 | ||
Nature and biological significance of DNA modification by the haloethylnitrosoureas | Q42218246 | ||
Formation of cyclic adducts in nucleic acids by the haloethylnitrosoureas | Q42223206 | ||
In vivo hprt mutant frequencies in T-cells of normal human newborns | Q44107832 | ||
Miscoding properties of 1,N6-ethanoadenine, a DNA adduct derived from reaction with the antitumor agent 1,3-bis(2-chloroethyl)-1-nitrosourea | Q44668728 | ||
P433 | issue | 3 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | Escherichia coli | Q25419 |
genotoxicity | Q1009245 | ||
P304 | page(s) | 755-60 | |
P577 | publication date | 2007-01-16 | |
P1433 | published in | Proceedings of the National Academy of Sciences of the United States of America | Q1146531 |
P1476 | title | Alleviation of 1,N6-ethanoadenine genotoxicity by the Escherichia coli adaptive response protein AlkB | |
P478 | volume | 104 |
Q33908269 | 1,3-Butadiene-Induced Adenine DNA Adducts Are Genotoxic but Only Weakly Mutagenic When Replicated in Escherichia coli of Various Repair and Replication Backgrounds |
Q33873044 | Adaptive Response Enzyme AlkB Preferentially Repairs 1-Methylguanine and 3-Methylthymine Adducts in Double-Stranded DNA |
Q36508674 | AlkB dioxygenase preferentially repairs protonated substrates: specificity against exocyclic adducts and molecular mechanism of action |
Q36734574 | Alkbh2 protects against lethality and mutation in primary mouse embryonic fibroblasts |
Q37467370 | Bioinformatics and functional analysis define four distinct groups of AlkB DNA-dioxygenases in bacteria |
Q93048317 | Biological Evaluation of DNA Biomarkers in a Chemically Defined and Site-Specific Manner |
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Q33575712 | Chemical biology of mutagenesis and DNA repair: cellular responses to DNA alkylation |
Q36745140 | Comprehensive Assessment of Oxidatively Induced Modifications of DNA in a Rat Model of Human Wilson's Disease |
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Q38071280 | DNA repair by reversal of DNA damage |
Q64985712 | DNA repair enzymes ALKBH2, ALKBH3, and AlkB oxidize 5-methylcytosine to 5-hydroxymethylcytosine, 5-formylcytosine and 5-carboxylcytosine in vitro. |
Q36538528 | Electrochemical characterization of Escherichia coli adaptive response protein AidB |
Q27657178 | Enzymological and structural studies of the mechanism of promiscuous substrate recognition by the oxidative DNA repair enzyme AlkB |
Q35997782 | Exocyclic carbons adjacent to the N6 of adenine are targets for oxidation by the Escherichia coli adaptive response protein AlkB. |
Q27675105 | Flavin-Induced Oligomerization in Escherichia coli Adaptive Response Protein AidB |
Q28485078 | Human ALKBH4 interacts with proteins associated with transcription |
Q36328944 | Kinetic studies of Escherichia coli AlkB using a new fluorescence-based assay for DNA demethylation |
Q34181987 | Mechanism of repair of acrolein- and malondialdehyde-derived exocyclic guanine adducts by the α-ketoglutarate/Fe(II) dioxygenase AlkB |
Q46007896 | Mutagenic potency of MMS-induced 1meA/3meC lesions in E. coli. |
Q35770590 | Next-generation sequencing reveals the biological significance of the N(2),3-ethenoguanine lesion in vivo |
Q37727692 | Nucleic acid oxidation in DNA damage repair and epigenetics |
Q33874560 | Oncometabolites d- and l-2-Hydroxyglutarate Inhibit the AlkB Family DNA Repair Enzymes under Physiological Conditions |
Q38218590 | Oxidative demethylation of DNA and RNA mediated by non-heme iron-dependent dioxygenases. |
Q35184695 | Protozoan ALKBH8 oxygenases display both DNA repair and tRNA modification activities |
Q36440706 | Quantitative measurement of transcriptional inhibition and mutagenesis induced by site-specifically incorporated DNA lesions in vitro and in vivo |
Q30858523 | Recognition and processing of a new repertoire of DNA substrates by human 3-methyladenine DNA glycosylase (AAG). |
Q37108058 | Removal of N-alkyl modifications from N(2)-alkylguanine and N(4)-alkylcytosine in DNA by the adaptive response protein AlkB |
Q34247869 | Repair of DNA Alkylation Damage by the Escherichia coli Adaptive Response Protein AlkB as Studied by ESI-TOF Mass Spectrometry. |
Q37287385 | Roles of Aag, Alkbh2, and Alkbh3 in the Repair of Carboxymethylated and Ethylated Thymidine Lesions |
Q34032004 | Schizosaccharomyces pombe Ofd2 is a nuclear 2-oxoglutarate and iron dependent dioxygenase interacting with histones |
Q24317323 | Spectroscopic and magnetic studies of wild-type and mutant forms of the Fe(II)- and 2-oxoglutarate-dependent decarboxylase ALKBH4 |
Q35978195 | The AlkB Family of Fe(II)/α-Ketoglutarate-dependent Dioxygenases: Repairing Nucleic Acid Alkylation Damage and Beyond |
Q36144836 | The DNA dioxygenase ALKBH2 protects Arabidopsis thaliana against methylation damage |
Q36018582 | The aminoglycoside antibiotic kanamycin damages DNA bases in Escherichia coli: caffeine potentiates the DNA-damaging effects of kanamycin while suppressing cell killing by ciprofloxacin in Escherichia coli and Bacillus anthracis |
Q36909341 | Viral AlkB proteins repair RNA damage by oxidative demethylation |
Q36672334 | XRCC1 and base excision repair balance in response to nitric oxide |