Repairing DNA-methylation damage

scientific article published on February 2004

Repairing DNA-methylation damage is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.1038/NRM1312
P8608Fatcat IDrelease_c64diyxas5ckfk2e3pbpqt4vf4
P698PubMed publication ID15040447

P2093author name stringBarbara Sedgwick
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Alteration in the choice of DNA repair pathway with increasing sequence selective DNA alkylation in the minor grooveQ74297565
Detection of concomitant formation of O6-carboxymethyl- and O6-methyl-2'-deoxyguanosine in DNA exposed to nitrosated glycine derivatives using a combined immunoaffinity/HPLC methodQ77810415
Methylation-induced blocks to in vitro DNA replicationQ93559108
Hyperthermostable protein structure maintained by intra and inter-helix ion-pairs in archaeal O6-methylguanine-DNA methyltransferaseQ27619727
Crystal structure of the human O(6)-alkylguanine-DNA alkyltransferaseQ27620779
Structural basis for the functional switch of the E. coli Ada proteinQ27630962
3-Methyladenine DNA glycosylase I is an unexpected helix-hairpin-helix superfamily memberQ27639455
A novel zinc snap motif conveys structural stability to 3-methyladenine DNA glycosylase IQ27640782
The essential Gcd10p-Gcd14p nuclear complex is required for 1-methyladenosine modification and maturation of initiator methionyl-tRNA.Q27933930
Cloning a eukaryotic DNA glycosylase repair gene by the suppression of a DNA repair defect in Escherichia coliQ27937308
Molecular cloning and functional analysis of a human cDNA encoding an Escherichia coli AlkB homolog, a protein involved in DNA alkylation damage repairQ28116035
Regulatory responses of the adaptive response to alkylation damage: a simple regulon with complex regulatory featuresQ28143623
Structural studies of human alkyladenine glycosylase and E. coli 3-methyladenine glycosylaseQ28143932
Oxidative demethylation by Escherichia coli AlkB directly reverts DNA base damageQ28201532
Human Alkyladenine DNA Glycosylase Uses Acid−Base Catalysis for Selective Excision of Damaged PurinesQ28211163
Increased spontaneous mutation and alkylation sensitivity of Escherichia coli strains lacking the ogt O6-methylguanine DNA repair methyltransferaseQ28268090
Regulation and expression of the adaptive response to alkylating agentsQ28289093
MutT protein specifically hydrolyses a potent mutagenic substrate for DNA synthesisQ28343030
Separation of killing and tumorigenic effects of an alkylating agent in mice defective in two of the DNA repair genesQ28586442
Excision of hypoxanthine from DNA containing dIMP residues by the Escherichia coli, yeast, rat, and human alkylpurine DNA glycosylasesQ28610597
Human and bacterial oxidative demethylases repair alkylation damage in both RNA and DNAQ29618091
AlkB-mediated oxidative demethylation reverses DNA damage in Escherichia coliQ29618092
Excision of 8-methylguanine site-specifically incorporated into oligonucleotide substrates by the AlkA protein of Escherichia coli.Q31123523
Alkylpurine-DNA-N-glycosylase knockout mice show increased susceptibility to induction of mutations by methyl methanesulfonateQ33780508
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Release of normal bases from intact DNA by a native DNA repair enzymeQ33888049
Unmasking a killer: DNA O(6)-methylguanine and the cytotoxicity of methylating agentsQ33892805
Base excision repair in yeast and mammalsQ33984258
Conserved structural motifs governing the stoichiometric repair of alkylated DNA by O(6)-alkylguanine-DNA alkyltransferaseQ34006340
The iron(II) and 2-oxoacid-dependent dioxygenases and their role in metabolismQ34051063
Chloride methylation by plant pectin: an efficient environmentally significant process.Q34213537
Crystallizing thoughts about DNA base excision repairQ34367271
The major human abasic endonuclease: formation, consequences and repair of abasic lesions in DNA.Q34390593
Reversal of DNA alkylation damage by two human dioxygenasesQ34429515
O6-alkylguanine-DNA alkyltransferase: role in carcinogenesis and chemotherapyQ34561510
Clinical relevance of MGMT in the treatment of cancerQ34617664
Non-heme iron oxygenasesQ34662093
Recent progress on the Ada response for inducible repair of DNA alkylation damageQ35026363
Improvement of chemotherapy efficacy by inactivation of a DNA-repair pathwayQ35040981
DNA repair by bacterial AlkB proteins.Q35550854
Suppression of Escherichia coli alkB mutants by Saccharomyces cerevisiae genesQ35593508
The Ada protein acts as both a positive and a negative modulator of Escherichia coli's response to methylating agents.Q35809531
The Escherichia coli AlkB protein protects human cells against alkylation-induced toxicityQ35979427
DNA alkylation repair limits spontaneous base substitution mutations in Escherichia coliQ36107979
Escherichia coli mutants deficient in deoxyuridine triphosphataseQ36419435
Release of N2,3-ethenoguanine from chloroacetaldehyde-treated DNA by Escherichia coli 3-methyladenine DNA glycosylase IIQ37233432
Possible depletion of a DNA repair enzyme in human lymphoma cells by subversive repairQ37527471
Active site and complete sequence of the suicidal methyltransferase that counters alkylation mutagenesisQ37685706
The E. coli ogt geneQ37984295
Substrate specificity of human methylpurine DNA N-glycosylaseQ38315191
Effect of base, pentose, and phosphodiester backbone structures on binding and repair of pyrimidine dimers by Escherichia coli DNA photolyaseQ38333470
Minimal methylated substrate and extended substrate range of Escherichia coli AlkB protein, a 1-methyladenine-DNA dioxygenaseQ38351039
The RNA Modification Database: 1999 updateQ38548527
Interactions of the human, rat, Saccharomyces cerevisiae and Escherichia coli 3-methyladenine-DNA glycosylases with DNA containing dIMP residuesQ39586073
Repair System for Noncanonical Purines in Escherichia coliQ39749064
Generation of an endogenous DNA-methylating agent by nitrosation in Escherichia coliQ39842494
An alkB gene homolog is differentially transcribed during the Caulobacter crescentus cell cycleQ39845655
Structure and transcriptional regulation of the Escherichia coli adaptive response gene aidB.Q39898811
A new gene (alkB) of Escherichia coli that controls sensitivity to methyl methane sulfonateQ39988721
Phase II trial of carmustine plus O(6)-benzylguanine for patients with nitrosourea-resistant recurrent or progressive malignant gliomaQ40643756
A new pathway for DNA repair in Escherichia coliQ40775216
Environmental mutagens that induce the adaptive response to alkylating agents in Escherichia coliQ41968976
Evidence in Escherichia coli that N3-methyladenine lesions induced by a minor groove binding methyl sulfonate ester can be processed by both base and nucleotide excision repairQ43591625
Molecular cloning and characterization of the alkB gene of Escherichia coliQ43696980
Binding of specific DNA base-pair mismatches by N-methylpurine-DNA glycosylase and its implication in initial damage recognitionQ44049721
The selectivity and inhibition of AlkB.Q44272023
How Do DNA Repair Proteins Locate Potential Base Lesions? A Chemical Crosslinking Method to Investigate O6-Alkylguanine-DNA AlkyltransferasesQ44604591
Repair in Escherichia coli alkB mutants of abasic sites and 3-methyladenine residues in DNA.Q47938067
A Watson-Crick base-pair-disrupting methyl group (m1A9) is sufficient for cloverleaf folding of human mitochondrial tRNALys.Q52536737
Probing the structure and function of the Escherichia coli DNA alkylation repair AlkB protein through chemical cross-linking.Q54521817
Converting the sacrificial DNA repair protein N-ada into a catalytic methyl phosphotriester repair enzyme.Q54530782
Nitrosated peptides and polyamines as endogenous mutagens in O6-alkylguanine-DNA alkyltransferase deficient cells.Q54561157
Induction of the adaptive response of Escherichia coli to alkylation damage by the environmental mutagen, methyl chlorideQ54661815
A Spectrophotometric Method for Determining the Oxidative Deamination of Methylamine by the Amine OxidasesQ64018970
Influence of hydrogen bonding in DNA and polynucleotides on reaction of nitrogens and oxygens toward ethylnitrosoureaQ66921091
Investigation of the specificity of O6-alkylguanine-DNA-alkyltransferaseQ69028851
Potent induction of the adaptive response by a weak mutagen, methyl iodide, in Escherichia coliQ70360690
Cytochrome P450 metabolic dealkylation of nine N-nitrosodialkylamines by human liver microsomesQ71574477
Mutagenesis by alkylating agents: coding properties for DNA polymerase of poly (dC) template containing 3-methylcytosineQ71627367
P433issue2
P921main subjectDNA methylationQ874745
P304page(s)148-157
P577publication date2004-02-01
P1433published inNature Reviews Molecular Cell BiologyQ1573120
P1476titleRepairing DNA-methylation damage
P478volume5

Reverse relations

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