Determinants of spontaneous mutation in the bacterium Escherichia coli as revealed by whole-genome sequencing

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Determinants of spontaneous mutation in the bacterium Escherichia coli as revealed by whole-genome sequencing is …
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scholarly articleQ13442814

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P819ADS bibcode2015PNAS..112E5990F
P356DOI10.1073/PNAS.1512136112
P932PMC publication ID4640725
P698PubMed publication ID26460006
P5875ResearchGate publication ID282874525

P50authorPatricia L. FosterQ41469351
P2093author name stringHaixu Tang
Heewook Lee
Ellen Popodi
Jesse P Townes
P2860cites workOrganised genome dynamics in the Escherichia coli species results in highly diverse adaptive pathsQ21090212
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MutT protein specifically hydrolyses a potent mutagenic substrate for DNA synthesisQ28343030
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THE GENETIC STRUCTURE OF NATURAL POPULATIONS OF DROSOPHILA MELANOGASTER. I. SPONTANEOUS MUTATION RATE OF POLYGENES CONTROLLING VIABILITYQ33981138
Error‐prone DNA polymerase IV is controlled by the stress‐response sigma factor, RpoS, in Escherichia coliQ34049897
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DNA alkylation repair limits spontaneous base substitution mutations in Escherichia coliQ36107979
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Escherichia coli strains with multiple DNA repair defects are hyperinduced for the SOS responseQ36256490
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Replication-transcription conflicts in bacteria.Q36307709
Rate and molecular spectrum of spontaneous mutations in the bacterium Escherichia coli as determined by whole-genome sequencing.Q36339832
The unusual mutagenic specificity of an E. Coli mutator geneQ36456280
Escherichia coli DNA polymerase III is responsible for the high level of spontaneous mutations in mutT strainsQ36566407
On the mutational topology of the bacterial genomeQ36642223
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No gene-specific optimization of mutation rate in Escherichia coliQ36935351
Stress-induced mutagenesis in bacteria.Q36961683
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DNA polymerase switching: effects on spontaneous mutagenesis in Escherichia coliQ37188497
Polymerases leave fingerprints: analysis of the mutational spectrum in Escherichia coli rpoB to assess the role of polymerase IV in spontaneous mutationQ37424859
Increased motility of Escherichia coli by insertion sequence element integration into the regulatory region of the flhD operonQ37596086
Mapping structurally defined guanine oxidation products along DNA duplexes: influence of local sequence context and endogenous cytosine methylationQ37701731
The endonuclease IV family of apurinic/apyrimidinic endonucleasesQ37776340
Transcription-coupled DNA repair in prokaryotesQ38022931
Endonuclease V: an unusual enzyme for repair of DNA deaminationQ38069442
Transcription-associated mutagenesisQ38253934
Spontaneous mutation rates come into focus in Escherichia coliQ38259429
MutY-glycosylase: an overview on mutagenesis and activities beyond the GO systemQ38378258
Protein family classification based on searching a database of blocksQ38568514
Escherichia coli MutY protein has a guanine-DNA glycosylase that acts on 7,8-dihydro-8-oxoguanine:guanine mispair to prevent spontaneous G:C-->C:G transversionsQ39725401
Generation of an endogenous DNA-methylating agent by nitrosation in Escherichia coliQ39842494
Characterization of endonuclease III (nth) and endonuclease VIII (nei) mutants of Escherichia coli K-12.Q39846025
Paradoxical hotspots for guanine oxidation by a chemical mediator of inflammationQ40271694
Newly identified genetic variations in common Escherichia coli MG1655 stock culturesQ40346767
Detection of messenger RNA from the isoleucine-valine operons of Salmonella typhimurium by heterologous DNA-RNA hybridization: Involvement of transfer RNA in transcriptional repressionQ40783410
Isolation and characterization of mutants of Escherichia coli deficient in induction of mutations by ultraviolet lightQ40850491
Mechanisms of directed mutationQ41110210
On fluctuation analysis: a new, simple and efficient method for computing the expected number of mutantsQ41645462
Mapping of peroxyl radical induced damage on genomic DNA.Q41708484
Mechanisms of spontaneous and induced frameshift mutation in bacteriophage T4.Q41879395
DNA sequence context as a determinant of the quantity and chemistry of guanine oxidation produced by hydroxyl radicals and one-electron oxidantsQ41932407
An aerobic recA-, umuC-dependent pathway of spontaneous base-pair substitution mutagenesis in Escherichia coliQ42498856
Methods for determining spontaneous mutation ratesQ42620101
DNA repair excision nuclease attacks undamaged DNA. A potential source of spontaneous mutationsQ43608425
A repair system for 8-oxo-7,8-dihydrodeoxyguanineQ43687308
Roles of chromosomal and episomal dinB genes encoding DNA pol IV in targeted and untargeted mutagenesis in Escherichia coli.Q43781879
Interactions among the Escherichia coli mutT, mutM, and mutY damage prevention pathwaysQ44280600
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Spontaneous mutagenesis associated with nucleotide excision repair in Escherichia coliQ45401435
Spontaneous mutators in bacteria: insights into pathways of mutagenesis and repairQ46617407
Effect of deletion of SOS-induced polymerases, pol II, IV, and V, on spontaneous mutagenesis in Escherichia coli mutD5.Q47609306
Effects on sister chromatid exchange frequency of aldehyde dehydrogenase 2 genotype and smoking in vinyl chloride workers.Q53428596
Much of spontaneous mutagenesis in Escherichia coli is due to error-prone DNA repair: implications for spontaneous carcinogenesis.Q54542097
Enzymatic processing of radiation-induced free radical damage in DNAQ62061101
NMR structural studies of the ionizing radiation adduct 7-hydro-8-oxodeoxyguanosine (8-oxo-7H-dG) opposite deoxyadenosine in a DNA duplex. 8-Oxo-7H-dG(syn).dA(anti) alignment at lesion siteQ68189284
Spectra of superoxide-induced mutations in the lacI gene of a wild-type and a mutM strain of Escherichia coli K-12Q71668940
A UmuD,C-dependent pathway for spontaneous G:C to C:G transversions in stationary phase Escherichia coli mut YQ73094277
Characterization of a novel 8-oxoguanine-DNA glycosylase activity in Escherichia coli and identification of the enzyme as endonuclease VIIIQ73914620
Mutagenicity and repair of oxidative DNA damage: insights from studies using defined lesionsQ95807087
P433issue44
P407language of work or nameEnglishQ1860
P921main subjectEscherichia coliQ25419
urban ecologyQ1430301
whole genome sequencingQ2068526
P304page(s)E5990-9
P577publication date2015-10-12
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleDeterminants of spontaneous mutation in the bacterium Escherichia coli as revealed by whole-genome sequencing
P478volume112

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