Mutator genomes decay, despite sustained fitness gains, in a long-term experiment with bacteria

scientific article published on 10 October 2017

Mutator genomes decay, despite sustained fitness gains, in a long-term experiment with bacteria is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1073/PNAS.1705887114
P932PMC publication ID5664506
P698PubMed publication ID29073099

P50authorRichard LenskiQ713637
Martin WeigtQ30505118
Alejandro CouceQ57016708
Olivier TenaillonQ89436407
Jean-Paul FeugeasQ115606253
P2093author name stringDominique Schneider
Thomas Hindré
Christoph Feinauer
Larissa Viraphong Caudwell
P2860cites workThe mosaic genome of Anaeromyxobacter dehalogenans strain 2CP-C suggests an aerobic common ancestor to the delta-proteobacteriaQ21144320
Wright and Fisher on inbreeding and random driftQ22065132
Experimental Determination and System Level Analysis of Essential Genes in Escherichia coli MG1655Q22065459
Extraordinary expansion of a Sorangium cellulosum genome from an alkaline milieuQ22121976
The codon Adaptation Index--a measure of directional synonymous codon usage bias, and its potential applicationsQ24498207
Genetic drift in an infinite population. The pseudohitchhiking modelQ24548113
Direct-coupling analysis of residue coevolution captures native contacts across many protein familiesQ24627074
Second-order selection for evolvability in a large Escherichia coli populationQ24635911
A method and server for predicting damaging missense mutationsQ27860835
The first steps of adaptation of Escherichia coli to the gut are dominated by soft sweepsQ28235419
Small, smaller, smallest: the origins and evolution of ancient dual symbioses in a Phloem-feeding insectQ28296073
Adaptation, Clonal Interference, and Frequency-Dependent Interactions in a Long-Term Evolution Experiment with Escherichia coliQ28647522
Genome dynamics during experimental evolutionQ28651650
Pfam: the protein families databaseQ28660698
Evolution of the cancer genomeQ28678232
Mutation rate dynamics in a bacterial population reflect tension between adaptation and genetic loadQ28710085
Functional Convergence in Reduced Genomes of Bacterial Symbionts Spanning 200 My of EvolutionQ28748909
Predicting the effects of coding non-synonymous variants on protein function using the SIFT algorithmQ29547194
Search and clustering orders of magnitude faster than BLASTQ29547431
Amino acid difference formula to help explain protein evolutionQ29614440
An ordered, nonredundant library of Pseudomonas aeruginosa strain PA14 transposon insertion mutantsQ29614860
Cost-minimization of amino acid usage.Q30332479
Parallel bacterial evolution within multiple patients identifies candidate pathogenicity genes.Q30426714
Evidence that mutation is universally biased towards AT in bacteriaQ30989309
Horizontal gene transfer regulation in bacteria as a "spandrel" of DNA repair mechanismsQ33303661
Assessing the potential of mutational strategies to elicit new phenotypes in industrial strainsQ33318340
A phylogenomic study of DNA repair genes, proteins, and processesQ33884321
The population genetics of ecological specialization in evolving Escherichia coli populationsQ33922714
Bacterial genome size reduction by experimental evolutionQ33922858
Deletional bias and the evolution of bacterial genomesQ33955011
Identifying genetic determinants needed to establish a human gut symbiont in its habitatQ33955014
Haemophilus influenzae bacteremia and meningitis resulting from survival of a single organismQ33969452
Improvement of microbial strains and fermentation processesQ34059420
Molecular basis of base substitution hotspots in Escherichia coliQ34183770
Extreme genome reduction in symbiotic bacteriaQ34230656
The speed of evolution and maintenance of variation in asexual populationsQ34330675
Pervasive genetic hitchhiking and clonal interference in forty evolving yeast populationsQ34358875
Metabolic erosion primarily through mutation accumulation, and not tradeoffs, drives limited evolution of substrate specificity in Escherichia coliQ34405876
Evolution of high mutation rates in experimental populations of E. coliQ34429727
Regulation of mutY and nature of mutator mutations in Escherichia coli populations under nutrient limitationQ34434306
Origins and evolution of viruses of eukaryotes: The ultimate modularityQ34467155
Coevolutionary Landscape Inference and the Context-Dependence of Mutations in Beta-Lactamase TEM-1.Q34497324
The Pfam protein families database: towards a more sustainable futureQ34505322
Tempo and mode of genome evolution in a 50,000-generation experimentQ34535938
MmeI: a minimal Type II restriction-modification system that only modifies one DNA strand for host protectionQ34598959
Mutators, population size, adaptive landscape and the adaptation of asexual populations of bacteriaQ34607018
Analysis of Bottlenecks in Experimental Models of InfectionQ34670588
The role of mutators in the emergence of antibiotic-resistant bacteriaQ35177659
Emergent neutrality in adaptive asexual evolutionQ35620493
Recombinant transfer in the basic genome of Escherichia coli.Q35895593
Determinants of spontaneous mutation in the bacterium Escherichia coli as revealed by whole-genome sequencingQ36268415
Unequal fidelity of leading strand and lagging strand DNA replication on the Escherichia coli chromosomeQ36283328
Rate and molecular spectrum of spontaneous mutations in the bacterium Escherichia coli as determined by whole-genome sequencing.Q36339832
Spontaneously Arising mutL Mutators in Evolving Escherichia coli Populations Are the Result of Changes in Repeat LengthQ36474342
Synchronous waves of failed soft sweeps in the laboratory: remarkably rampant clonal interference of alleles at a single locusQ36643918
Whole-genome mutational biases in bacteriaQ36976728
Capturing the mutational landscape of the beta-lactamase TEM-1.Q37088726
Mistranslation-induced protein misfolding as a dominant constraint on coding-sequence evolution.Q37227320
Mutators and sex in bacteria: conflict between adaptive strategiesQ37247776
Gene amplification and adaptive evolution in bacteria.Q37580926
Prochlorococcus: advantages and limits of minimalismQ37818053
Bacterial hypermutation: clinical implicationsQ37847007
Mutation effects predicted from sequence co-variationQ39018179
Phylogenetic evidence for horizontal transfer of mutS alleles among naturally occurring Escherichia coli strainsQ39502754
High frequency of mutator strains among human uropathogenic Escherichia coli isolates.Q39694657
Similar compositional biases are caused by very different mutational effects.Q39983675
Mechanisms of DNA replication and mutagenesis in ultraviolet-irradiated bacteria and mammalian cellsQ40260244
Quantitative evolutionary dynamics using high-resolution lineage trackingQ40499709
Links between Transcription, Environmental Adaptation and Gene Variability in Escherichia coli: Correlations between Gene Expression and Gene Variability Reflect Growth EfficienciesQ40633565
Intrapopulation variability in mutator prevalence among urinary tract infection isolates of Escherichia coli.Q40738041
Hitchhiking and epistasis give rise to cohort dynamics in adapting populationsQ41292956
Polymorphisms, Chromosomal Rearrangements, and Mutator Phenotype Development during Experimental Evolution of Lactobacillus rhamnosus GG.Q42118118
Highly expressed genes in yeast evolve slowly.Q42541336
Improved contact prediction in proteins: using pseudolikelihoods to infer Potts modelsQ42687387
Update on the Keio collection of Escherichia coli single-gene deletion mutantsQ42912234
High guanine plus cytosine content in the third letter of codons of an extreme thermophile. DNA sequence of the isopropylmalate dehydrogenase of Thermus thermophilusQ43021002
Understanding the differences between genome sequences of Escherichia coli B strains REL606 and BL21(DE3) and comparison of the E. coli B and K-12 genomesQ43274452
Aerobiosis increases the genomic guanine plus cytosine content (GC%) in prokaryotesQ44108765
Long-term dynamics of adaptation in asexual populationsQ45261637
Selection in a fluctuating environment leads to decreased genetic variation and facilitates the evolution of phenotypic plasticityQ45418203
Adaptive synonymous mutations in an experimentally evolved Pseudomonas fluorescens populationQ45772156
The temporal dynamics of slightly deleterious mutations in Escherichia coli and Shigella spp.Q46264312
Evidence for a human-specific Escherichia coli clone.Q46336053
Spontaneous mutators in bacteria: insights into pathways of mutagenesis and repairQ46617407
Clonal divergence in Escherichia coli as a result of recombination, not mutationQ48077857
Evolutionary implications of the frequent horizontal transfer of mismatch repair genesQ50117948
The spontaneous mutation frequencies of Prochlorococcus strains are commensurate with those of other bacteria.Q50913027
Reduced effectiveness of selection caused by a lack of recombination.Q51769904
Rapidly fluctuating environments constrain coevolutionary arms races by impeding selective sweeps.Q51872381
Base composition bias might result from competition for metabolic resources.Q52940121
Sustained fitness gains and variability in fitness trajectories in the long-term evolution experiment with Escherichia coli.Q53247059
Genomic divergence of Escherichia coli strains: evidence for horizontal transfer and variation in mutation rates.Q54468213
Diminishing Returns from Mutation Supply Rate in Asexual PopulationsQ56920120
Mutagenic deamination of cytosine residues in DNAQ59062016
Sunlight Ultraviolet and Bacterial DNA Base RatiosQ71577525
Mutation rate and genome reduction in endosymbiotic and free-living bacteriaQ80114206
P433issue43
P407language of work or nameEnglishQ1860
P304page(s)E9026-E9035
P577publication date2017-10-10
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleMutator genomes decay, despite sustained fitness gains, in a long-term experiment with bacteria
P478volume114

Reverse relations

cites work (P2860)
Q92912422Comparative Genomics of Antibiotic-Resistant Uropathogens Implicates Three Routes for Recurrence of Urinary Tract Infections
Q56875376Directed evolution of Escherichia coli with lower-than-natural plasmid mutation rates
Q89982990Epistatic contributions promote the unification of incompatible models of neutral molecular evolution
Q104064794Evolution of Pseudomonas aeruginosa toward higher fitness under standard laboratory conditions
Q64274021Evolutionary Changes after Translational Challenges Imposed by Horizontal Gene Transfer
Q94468774Evolutionary innovation using EDGE, a system for localized elevated mutagenesis
Q54260395Experimental evolution heals the scars of genome-scale recoding.
Q91902524Mutation bias and GC content shape antimutator invasions
Q90389384On the feasibility of saltational evolution
Q92572554Survival of the simplest in microbial evolution
Q91623019The Essential Role of Hypermutation in Rapid Adaptation to Antibiotic Stress
Q49320136The Odyssey of the Ancestral Escherich Strain through Culture Collections: an Example of Allopatric Diversification
Q92544990The emergence of adaptive laboratory evolution as an efficient tool for biological discovery and industrial biotechnology
Q58785293Why are RNA virus mutation rates so damn high?

Search more.