Chikungunya viruses that escape monoclonal antibody therapy are clinically attenuated, stable, and not purified in mosquitoes

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Chikungunya viruses that escape monoclonal antibody therapy are clinically attenuated, stable, and not purified in mosquitoes is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/JVI.01032-14
P932PMC publication ID4135940
P698PubMed publication ID24829346

P50authorMichael S. DiamondQ28051146
Stephen HiggsQ28320183
Dana VanlandinghamQ29381208
Julie M. FoxQ55190881
Thomas E MorrisonQ66829484
Yan-Jang S HuangQ84767331
Ilhem MessaoudiQ87616701
David W HawmanQ97635567
P2093author name stringSyd Johnson
Alfred W Legasse
Craig Kreklywich
Daniel N Streblow
Michael Denton
Michael K Axthelm
Pankaj Pal
Patricia P Smith
P2860cites workStructural analyses at pseudo atomic resolution of Chikungunya virus and antibodies show mechanisms of neutralizationQ21128795
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Re-emergence of Chikungunya and O'nyong-nyong viruses: evidence for distinct geographical lineages and distant evolutionary relationshipsQ24570057
Interferon response factors 3 and 7 protect against Chikungunya virus hemorrhagic fever and shockQ24598171
Persistent arthralgia induced by Chikungunya virus infection is associated with interleukin-6 and granulocyte macrophage colony-stimulating factorQ24625887
Type I IFN controls chikungunya virus via its action on nonhematopoietic cellsQ24647231
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The Fusion glycoprotein shell of Semliki Forest virus: an icosahedral assembly primed for fusogenic activation at endosomal pHQ27631190
Structural changes of envelope proteins during alphavirus fusionQ27666145
Glycoprotein organization of Chikungunya virus particles revealed by X-ray crystallographyQ27666147
A neutralizing monoclonal antibody targeting the acid-sensitive region in chikungunya virus E2 protects from diseaseQ28533408
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Changing patterns of chikungunya virus: re-emergence of a zoonotic arbovirusQ29620003
A humanized murine monoclonal antibody protects mice either before or after challenge with virulent Venezuelan equine encephalomyelitis virusQ33253169
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ISG15 is critical in the control of Chikungunya virus infection independent of UbE1L mediated conjugationQ34058142
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Attenuation of Chikungunya virus vaccine strain 181/clone 25 is determined by two amino acid substitutions in the E2 envelope glycoproteinQ34264257
Arthritogenic alphaviruses--an overviewQ34273343
A pathogenic role for CD4+ T cells during Chikungunya virus infection in miceQ34315384
Chronic joint disease caused by persistent Chikungunya virus infection is controlled by the adaptive immune responseQ34378105
Infection of myofibers contributes to increased pathogenicity during infection with an epidemic strain of chikungunya virusQ34391631
Infectious clones of Chikungunya virus (La Réunion isolate) for vector competence studiesQ34594476
Chikungunya in north-eastern Italy: a summing up of the outbreak.Q34720609
A mouse model of chikungunya virus-induced musculoskeletal inflammatory disease: evidence of arthritis, tenosynovitis, myositis, and persistenceQ34756658
Chikungunya virus infection results in higher and persistent viral replication in aged rhesus macaques due to defects in anti-viral immunityQ34927480
Deliberate attenuation of chikungunya virus by adaptation to heparan sulfate-dependent infectivity: a model for rational arboviral vaccine designQ35109218
Chikungunya virus neutralization antigens and direct cell-to-cell transmission are revealed by human antibody-escape mutantsQ35586877
Interferon-alpha/beta deficiency greatly exacerbates arthritogenic disease in mice infected with wild-type chikungunya virus but not with the cell culture-adapted live-attenuated 181/25 vaccine candidate.Q36200552
Chikungunya virus and prospects for a vaccineQ36582816
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Gene profiling of Chikungunya virus arthritis in a mouse model reveals significant overlap with rheumatoid arthritisQ37331952
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Chikungunya-related arthritis: case report and review of the literatureQ38100901
Chikungunya and dengue autochthonous cases in Europe, 2007-2012.Q38130346
A single-amino-acid polymorphism in Chikungunya virus E2 glycoprotein influences glycosaminoglycan utilizationQ38329445
Use of human monoclonal antibodies to treat Chikungunya virus infectionQ39012242
Dendritic cell immunoreceptor regulates Chikungunya virus pathogenesis in miceQ40254655
Venezuelan equine encephalitis virus complex-specific monoclonal antibody provides broad protection, in murine models, against airborne challenge with viruses from serogroups I, II and III.Q40290968
Protection from arthritis and myositis in a mouse model of acute chikungunya virus disease by bindarit, an inhibitor of monocyte chemotactic protein-1 synthesisQ40313646
Monoclonal antibodies that cross-react with the E1 glycoprotein of different alphavirus serogroups: characterization including passive protection in vivoQ41836576
Tracking epidemic Chikungunya virus into the Indian Ocean from East AfricaQ42062705
Neutralizing monoclonal antibodies to the E2 protein of chikungunya virus protects against disease in a mouse modelQ42240413
Genetic divergence of Chikungunya viruses in India (1963-2006) with special reference to the 2005-2006 explosive epidemicQ42623122
Structure and interactions at the viral surface of the envelope protein E1 of Semliki Forest virusQ42677821
Chikungunya in EuropeQ43046500
Persistent arthralgia associated with chikungunya virus: a study of 88 adult patients on reunion islandQ44851009
An animal model for studying the pathogenesis of chikungunya virus infectionQ44851012
Chikungunya in Europe.Q44851114
Neutralizing and non-neutralizing monoclonal antibodies to the E2 glycoprotein of Semliki Forest virus can protect mice from lethal encephalitisQ45793971
Host defenses during primary Venezuelan equine encephalomyelitis virus infection in mice. I. Passive transfer of protection with immune serum and immune cellsQ45819843
Synthetic peptides of Venezuelan equine encephalomyelitis virus E2 glycoprotein. III. Identification of a protective peptide derived from the carboxy-terminal extramembranal one-third of the proteinQ45853854
Non-neutralizing monoclonal antibodies can prevent lethal alphavirus encephalitisQ59070308
Antibody-mediated clearance of alphavirus infection from neuronsQ68262671
P433issue15
P407language of work or nameEnglishQ1860
P921main subjectantibodyQ79460
chikungunyaQ243257
Chikungunya virusQ15794049
monoclonal antibodyQ422248
P5008on focus list of Wikimedia projectScienceSourceQ55439927
P304page(s)8213-26
P577publication date2014-08-01
P1433published inJournal of VirologyQ1251128
P1476titleChikungunya viruses that escape monoclonal antibody therapy are clinically attenuated, stable, and not purified in mosquitoes
P478volume88

Reverse relations

cites work (P2860)
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Q44843465Chikungunya Virus: Pathophysiology, Mechanism, and Modeling
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Q30235512Chikungunya virus: epidemiology, replication, disease mechanisms, and prospective intervention strategies
Q94561515Current Efforts in the Development of Vaccines for the Prevention of Zika and Chikungunya Virus Infections
Q24701766Exposure of epitope residues on the outer face of the chikungunya virus envelope trimer determines antibody neutralizing efficacy
Q78177480Human monoclonal antibodies against chikungunya virus target multiple distinct epitopes in the E1 and E2 glycoproteins.
Q54247380Human-Like Neutralizing Antibodies Protect Mice from Aerosol Exposure with Western Equine Encephalitis Virus.
Q39038535IgG Fc variant cross-reactivity between human and rhesus macaque FcγRs
Q39013750Immune-Mediated Protection and Pathogenesis of Chikungunya Virus
Q35850197Isolation and Characterization of Broad and Ultrapotent Human Monoclonal Antibodies with Therapeutic Activity against Chikungunya Virus
Q40077669Monoclonal Antibodies as Prophylactic and Therapeutic Agents Against Chikungunya Virus
Q40656589Mouse Models of Chikungunya Virus
Q92133744Neutralizing antibodies against Mayaro virus require Fc effector functions for protective activity
Q26782722Nonhuman Primate Models of Chikungunya Virus Infection and Disease (CHIKV NHP Model)
Q91842996Optimal therapeutic activity of monoclonal antibodies against chikungunya virus requires Fc-FcγR interaction on monocytes
Q59350546Protective antibodies against Eastern equine encephalitis virus bind to epitopes in domains A and B of the E2 glycoprotein
Q35861232Sequence-Specific Modifications Enhance the Broad-Spectrum Antiviral Response Activated by RIG-I Agonists
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Q38157882Vertebrate Reservoirs of Arboviruses: Myth, Synonym of Amplifier, or Reality?
Q28954543Zika Virus infection of rhesus macaques leads to viral persistence in multiple tissues

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