scholarly article | Q13442814 |
P2093 | author name string | Hao Li | |
Peter Walter | |||
Christopher K Patil | |||
P2860 | cites work | Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress | Q22010800 |
Finding Functional Features in Saccharomyces Genomes by Phylogenetic Footprinting | Q22065823 | ||
Sequencing and comparison of yeast species to identify genes and regulatory elements | Q22122502 | ||
ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs | Q24290776 | ||
Endoplasmic reticulum stress-induced formation of transcription factor complex ERSF including NF-Y (CBF) and activating transcription factors 6alpha and 6beta that activates the mammalian unfolded protein response | Q24548363 | ||
Mammalian eukaryotic initiation factor 2 alpha kinases functionally substitute for GCN2 protein kinase in the GCN4 translational control mechanism of yeast | Q24562926 | ||
Comparison of the consensus sequence flanking translational start sites in Drosophila and vertebrates | Q24629553 | ||
IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response | Q24672592 | ||
IRE1-independent gain control of the unfolded protein response | Q24798921 | ||
Transcriptional regulatory networks in Saccharomyces cerevisiae | Q27860846 | ||
Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae | Q27861085 | ||
A transmembrane protein with a cdc2+/CDC28-related kinase activity is required for signaling from the ER to the nucleus | Q27930818 | ||
A regulatory link between ER-associated protein degradation and the unfolded-protein response | Q27931238 | ||
Signalling from endoplasmic reticulum to nucleus: transcription factor with a basic-leucine zipper motif is required for the unfolded protein-response pathway | Q27932953 | ||
The transmembrane kinase Ire1p is a site-specific endonuclease that initiates mRNA splicing in the unfolded protein response | Q27933479 | ||
Gene-specific translational control of the yeast GCN4 gene by phosphorylation of eukaryotic initiation factor 2. | Q27934963 | ||
A novel mechanism for regulating activity of a transcription factor that controls the unfolded protein response | Q27938493 | ||
Transcriptional induction of genes encoding endoplasmic reticulum resident proteins requires a transmembrane protein kinase | Q27938837 | ||
tRNA ligase is required for regulated mRNA splicing in the unfolded protein response | Q27940124 | ||
Functional and genomic analyses reveal an essential coordination between the unfolded protein response and ER-associated degradation | Q28131669 | ||
Perk is essential for translational regulation and cell survival during the unfolded protein response | Q28140062 | ||
IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA | Q28214814 | ||
Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase | Q28296183 | ||
The proteasome regulates the UV-induced activation of the AP-1-like transcription factor Gcn4 | Q28346040 | ||
Regulated translation initiation controls stress-induced gene expression in mammalian cells | Q28506388 | ||
Characterization of mouse Ire1 alpha: cloning, mRNA localization in the brain and functional analysis in a neural cell line | Q28586245 | ||
Regulatory element detection using a probabilistic segmentation model. | Q52074413 | ||
Genetic evidence for functional specificity of the yeast GCN2 kinase | Q57243225 | ||
The role of DNA replication in the repression of the yeast mating-type silent loci | Q57270210 | ||
The bZIP domains of Fos and Jun mediate a physical association with the TATA box-binding protein | Q58796390 | ||
Heme regulates transcription of the CYC1 gene of S. cerevisiae via an upstream activation site | Q67284397 | ||
Genetic and biochemical evidence for yeast GCN2 protein kinase polymerization | Q72499579 | ||
Degradation of proteins from the ER of S. cerevisiae requires an intact unfolded protein response pathway | Q73958524 | ||
Two distinct stress signaling pathways converge upon the CHOP promoter during the mammalian unfolded protein response | Q74359929 | ||
Palindrome with spacer of one nucleotide is characteristic of the cis-acting unfolded protein response element in Saccharomyces cerevisiae | Q74450519 | ||
Monitoring the Gcn4 protein-mediated response in the yeast Saccharomyces cerevisiae | Q74531608 | ||
Cloning of mammalian Ire1 reveals diversity in the ER stress responses | Q28587224 | ||
Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae | Q29546523 | ||
An integrated stress response regulates amino acid metabolism and resistance to oxidative stress | Q29547441 | ||
Transcriptional profiling shows that Gcn4p is a master regulator of gene expression during amino acid starvation in yeast | Q29614487 | ||
Identifying DNA and protein patterns with statistically significant alignments of multiple sequences | Q29615307 | ||
Clustering gene expression patterns | Q33882299 | ||
A 22 bp cis-acting element is necessary and sufficient for the induction of the yeast KAR2 (BiP) gene by unfolded proteins | Q33938056 | ||
Chemical inhibition of the Pho85 cyclin-dependent kinase reveals a role in the environmental stress response | Q33947897 | ||
Glucose limitation induces GCN4 translation by activation of Gcn2 protein kinase | Q33962759 | ||
IRE1 and efferent signaling from the endoplasmic reticulum. | Q34062577 | ||
Block of HAC1 mRNA translation by long-range base pairing is released by cytoplasmic splicing upon induction of the unfolded protein response | Q34094604 | ||
Intracellular signaling from the endoplasmic reticulum to the nucleus: the unfolded protein response in yeast and mammals | Q34245400 | ||
A role for Hsp90 in retinoid receptor signal transduction | Q34454414 | ||
Translational control by TOR and TAP42 through dephosphorylation of eIF2alpha kinase GCN2. | Q35964633 | ||
Fos and Jun repress transcription activation by NF-IL6 through association at the basic zipper region | Q36643268 | ||
Building a dictionary for genomes: identification of presumptive regulatory sites by statistical analysis | Q37408450 | ||
GCN4 binds with high affinity to DNA sequences containing a single consensus half-site | Q38311899 | ||
Endoplasmic reticulum stress-induced mRNA splicing permits synthesis of transcription factor Hac1p/Ern4p that activates the unfolded protein response | Q38614162 | ||
Endoproteolysis of the ER stress transducer ATF6 in the presence of functionally inactive presenilins | Q40787709 | ||
Translational regulation of yeast GCN4. A window on factors that control initiator-trna binding to the ribosome | Q41575247 | ||
The promoter region of the yeast KAR2 (BiP) gene contains a regulatory domain that responds to the presence of unfolded proteins in the endoplasmic reticulum | Q42083502 | ||
Monomeric and dimeric bZIP transcription factor GCN4 bind at the same rate to their target DNA site | Q44733820 | ||
Activation of ATF6 and an ATF6 DNA binding site by the endoplasmic reticulum stress response. | Q45345766 | ||
Translational attenuation mediated by an mRNA intron | Q46210134 | ||
Ligand-independent dimerization activates the stress response kinases IRE1 and PERK in the lumen of the endoplasmic reticulum. | Q50336389 | ||
P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
P6216 | copyright status | copyrighted | Q50423863 |
P433 | issue | 8 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | E246 | |
P577 | publication date | 2004-08-01 | |
P1433 | published in | PLOS Biology | Q1771695 |
P1476 | title | Gcn4p and novel upstream activating sequences regulate targets of the unfolded protein response | |
P478 | volume | 2 |
Q33398514 | A role for the unfolded protein response (UPR) in virulence and antifungal susceptibility in Aspergillus fumigatus |
Q37661678 | A single inhibitory upstream open reading frame (uORF) is sufficient to regulate Candida albicans GCN4 translation in response to amino acid starvation conditions |
Q46671627 | An ER-directed transcriptional response to unfolded protein stress in the absence of conserved sensor-transducer proteins in Giardia lamblia |
Q27933335 | Analysis of quality control substrates in distinct cellular compartments reveals a unique role for Rpn4p in tolerating misfolded membrane proteins. |
Q37903606 | Apoptosis and other cell death mechanisms after retinal detachment: implications for photoreceptor rescue |
Q36389392 | Basic leucine zipper transcription factor Hac1 binds DNA in two distinct modes as revealed by microfluidic analyses |
Q36362409 | Cellular response to endoplasmic reticulum stress: a matter of life or death |
Q25256765 | Common features and interesting differences in transcriptional responses to secretion stress in the fungi Trichoderma reesei and Saccharomyces cerevisiae |
Q33379295 | CompMoby: comparative MobyDick for detection of cis-regulatory motifs |
Q34106841 | Correlation of gene expression and protein production rate - a system wide study |
Q36031460 | Decreased secretion and unfolded protein response upregulation |
Q34029332 | Defects in the secretory pathway and high Ca2+ induce multiple P-bodies |
Q35111180 | Deletion of a subgroup of ribosome-related genes minimizes hypoxia-induced changes and confers hypoxia tolerance |
Q39975807 | Dephosphorylation of translation initiation factor 2alpha enhances glucose tolerance and attenuates hepatosteatosis in mice |
Q33287197 | Determinants of cell- and gene-specific transcriptional regulation by the glucocorticoid receptor |
Q33580281 | Editing of misaminoacylated tRNA controls the sensitivity of amino acid stress responses in Saccharomyces cerevisiae |
Q36820563 | Endoplasmic reticulum (ER) stress response and its physiological roles in plants |
Q36300785 | Endoplasmic reticulum stress and the making of a professional secretory cell |
Q35756699 | Endoplasmic reticulum stress regulation of the Kar2p/BiP chaperone alleviates proteotoxicity via dual degradation pathways |
Q36065191 | Evidence That Base-pairing Interaction between Intron and mRNA Leader Sequences Inhibits Initiation of HAC1 mRNA Translation in Yeast |
Q33409407 | Expression of two endoplasmic reticulum stress markers, GRP78 and GADD153, in rat retinal detachment model and its implication |
Q36739878 | Gcn4 is required for the response to peroxide stress in the yeast Saccharomyces cerevisiae. |
Q24794933 | Gene recruitment of the activated INO1 locus to the nuclear membrane |
Q34356834 | Genome-wide expression analysis upon constitutive activation of the HacA bZIP transcription factor in Aspergillus niger reveals a coordinated cellular response to counteract ER stress |
Q30832036 | Genomic analysis of the secretion stress response in the enzyme-producing cell factory Aspergillus niger |
Q90283332 | Global Proteome Remodeling during ER Stress Involves Hac1-Driven Expression of Long Undecoded Transcript Isoforms |
Q33518896 | Global transcriptional response after exposure of fission yeast cells to ultraviolet light |
Q27312348 | HIF-1 modulates dietary restriction-mediated lifespan extension via IRE-1 in Caenorhabditis elegans |
Q42030676 | HacA-dependent transcriptional switch releases hacA mRNA from a translational block upon endoplasmic reticulum stress |
Q41821383 | HacA-independent induction of chaperone-encoding gene bipA in Aspergillus niger strains overproducing membrane proteins |
Q36084569 | Hansenula polymorpha Hac1p Is Critical to Protein N-Glycosylation Activity Modulation, as Revealed by Functional and Transcriptomic Analyses |
Q51034395 | High-level extracellular production of glucose oxidase by recombinant Pichia pastoris using a combined strategy. |
Q24798921 | IRE1-independent gain control of the unfolded protein response |
Q37746418 | Identification of Genes in Saccharomyces cerevisiae that Are Haploinsufficient for Overcoming Amino Acid Starvation |
Q33295149 | Identification of eukaryotic promoter regulatory elements using nonhomologous random recombination |
Q33294925 | Impact of light on Hypocrea jecorina and the multiple cellular roles of ENVOY in this process |
Q35060167 | Investigation of protein secretion and secretion stress in Ashbya gossypii |
Q45324768 | Long-term adaptation of Saccharomyces cerevisiae to the burden of recombinant insulin production |
Q42825435 | Membrane stress is coupled to a rapid translational control of gene expression in chlorpromazine-treated cells. |
Q38005467 | Metabolic engineering of recombinant protein secretion by Saccharomyces cerevisiae |
Q35023439 | Metabolic-state-dependent remodeling of the transcriptome in response to anoxia and subsequent reoxygenation in Saccharomyces cerevisiae. |
Q42014972 | Mining metabolic pathways through gene expression |
Q36650395 | Mitochondrial Sulfide Quinone Oxidoreductase Prevents Activation of the Unfolded Protein Response in Hydrogen Sulfide |
Q38687153 | Moderate Expression of SEC16 Increases Protein Secretion by Saccharomyces cerevisiae |
Q33288188 | Monitoring of transcriptional regulation in Pichia pastoris under protein production conditions |
Q42573318 | Mutual cross talk between the regulators Hac1 of the unfolded protein response and Gcn4 of the general amino acid control of Saccharomyces cerevisiae. |
Q33983377 | Native-state stability determines the extent of degradation relative to secretion of protein variants from Pichia pastoris. |
Q36967979 | Novel suppressors of alpha-synuclein toxicity identified using yeast |
Q34283514 | Proline biosynthesis is required for endoplasmic reticulum stress tolerance in Saccharomyces cerevisiae |
Q34190184 | Protein Misfolding Induces Hypoxic Preconditioning via a Subset of the Unfolded Protein Response Machinery |
Q35160159 | Protein folding and quality control in the endoplasmic reticulum: Recent lessons from yeast and mammalian cell systems |
Q38230560 | Protein folding and secretion: mechanistic insights advancing recombinant protein production in S. cerevisiae. |
Q24681845 | SCFCdc4-mediated degradation of the Hac1p transcription factor regulates the unfolded protein response in Saccharomyces cerevisiae |
Q27860577 | Signal integration in the endoplasmic reticulum unfolded protein response |
Q64103892 | Signal peptide peptidase activity connects the unfolded protein response to plant defense suppression by Ustilago maydis |
Q46808416 | Stress-induced transcription of the endoplasmic reticulum oxidoreductin gene ERO1 in the yeast Saccharomyces cerevisiae |
Q34080071 | Survey of the transcriptome of Aspergillus oryzae via massively parallel mRNA sequencing |
Q28757131 | Systematic identification of cis-regulatory sequences active in mouse and human embryonic stem cells |
Q37610497 | Targeting tissue-specific metabolic signaling pathways in aging: the promise and limitations |
Q41630273 | The Gcn4 transcription factor reduces protein synthesis capacity and extends yeast lifespan |
Q58780328 | The Unfolded Protein Response Pathway in the Yeast . A Comparative View among Yeast Species |
Q38233812 | The importance of connections between the cell wall integrity pathway and the unfolded protein response in filamentous fungi |
Q27935088 | The thioredoxin system protects ribosomes against stress-induced aggregation |
Q33697922 | The unfolded protein response is not necessary for the G1/S transition, but it is required for chromosome maintenance in Saccharomyces cerevisiae |
Q27937309 | The unfolded protein response transducer Ire1p contains a nuclear localization sequence recognized by multiple beta importins |
Q27932969 | Trans-Golgi network and endosome dynamics connect ceramide homeostasis with regulation of the unfolded protein response and TOR signaling in yeast. |
Q33402631 | Transcriptomic comparison of Aspergillus niger growing on two different sugars reveals coordinated regulation of the secretory pathway |
Q92854165 | Translation Control of HAC1 by Regulation of Splicing in Saccharomyces cerevisiae |
Q38266662 | Unfolded protein response in filamentous fungi-implications in biotechnology. |
Q33912952 | With TOR, less is more: a key role for the conserved nutrient-sensing TOR pathway in aging |
Q37359194 | Yeast life span extension by depletion of 60s ribosomal subunits is mediated by Gcn4. |
Search more.