| scholarly article | Q13442814 |
| review article | Q7318358 |
| P6179 | Dimensions Publication ID | 1042741447 |
| P356 | DOI | 10.1186/AR325 |
| P932 | PMC publication ID | 128908 |
| P698 | PubMed publication ID | 11714387 |
| P5875 | ResearchGate publication ID | 11641692 |
| P2093 | author name string | J S Mort | |
| C J Billington | |||
| P2860 | cites work | Purification and cloning of aggrecanase-1: a member of the ADAMTS family of proteins | Q22009926 |
| Cloning and characterization of ADAMTS11, an aggrecanase from the ADAMTS family | Q22010479 | ||
| Biochemical characterization of human collagenase-3 | Q24318765 | ||
| ADAMTS-1 is an active metalloproteinase associated with the extracellular matrix | Q28137781 | ||
| Identification of the (183)RWTNNFREY(191) region as a critical segment of matrix metalloproteinase 1 for the expression of collagenolytic activity | Q28139348 | ||
| Matrix metalloproteinases | Q28140451 | ||
| ADAMTS-1 cleaves a cartilage proteoglycan, aggrecan | Q28142856 | ||
| Expression of ADAMTS homologues in articular cartilage | Q30732535 | ||
| The use of cleavage site specific antibodies to delineate protein processing and breakdown pathways | Q33706655 | ||
| The thrombospondin motif of aggrecanase-1 (ADAMTS-4) is critical for aggrecan substrate recognition and cleavage | Q33903185 | ||
| The new kids on the block: ADAMTSs, potentially multifunctional metalloproteinases of the ADAM family | Q33919176 | ||
| Aggrecan degradation in human cartilage. Evidence for both matrix metalloproteinase and aggrecanase activity in normal, osteoarthritic, and rheumatoid joints | Q37369629 | ||
| Multiple modes of activation of latent human fibroblast collagenase: evidence for the role of a Cys73 active-site zinc complex in latency and a "cysteine switch" mechanism for activation | Q37666731 | ||
| The activity of the tissue inhibitors of metalloproteinases is regulated by C-terminal domain interactions: a kinetic analysis of the inhibition of gelatinase A. | Q38319875 | ||
| Membrane type 1 matrix metalloproteinase digests interstitial collagens and other extracellular matrix macromolecules | Q41133261 | ||
| ADAMs in fertilization and development | Q41256420 | ||
| N-terminal sequence of proteoglycan fragments isolated from medium of interleukin-1-treated articular-cartilage cultures. Putative site(s) of enzymic cleavage | Q42682254 | ||
| Cathepsin B: an alternative protease for the generation of an aggrecan 'metalloproteinase' cleavage neoepitope | Q42991927 | ||
| An aggrecan-degrading activity associated with chondrocyte membranes | Q42992126 | ||
| Analysis of collagenase-cleavage of type II collagen using a neoepitope ELISA. | Q43517541 | ||
| The involvement of the fibronectin type II-like modules of human gelatinase A in cell surface localization and activation | Q47761007 | ||
| Identification of a stromelysin cleavage site within the interglobular domain of human aggrecan. Evidence for proteolysis at this site in vivo in human articular cartilage | Q67728172 | ||
| Cathepsin B in synovial cells at the site of joint destruction in rheumatoid arthritis | Q68061622 | ||
| Type II collagen degradation in spontaneous osteoarthritis in C57Bl/6 and BALB/c mice | Q73165857 | ||
| TIMP-3 is a potent inhibitor of aggrecanase 1 (ADAM-TS4) and aggrecanase 2 (ADAM-TS5) | Q73692795 | ||
| Inhibition of ADAMTS4 (aggrecanase-1) by tissue inhibitors of metalloproteinases (TIMP-1, 2, 3 and 4) | Q73779515 | ||
| The relative importance of cysteine peptidases in osteoarthritis | Q74214689 | ||
| Expression of cathepsin K messenger RNA in giant cells and their precursors in human osteoarthritic synovial tissues | Q78124698 | ||
| P433 | issue | 6 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | arthritis | Q170990 |
| cartilage | Q502730 | ||
| human musculoskeletal system | Q726543 | ||
| fibrous protein | Q1976174 | ||
| P304 | page(s) | 337-341 | |
| P577 | publication date | 2001-09-06 | |
| P1433 | published in | Arthritis Research and Therapy | Q15757229 |
| Arthritis Research | Q45128333 | ||
| P1476 | title | Articular cartilage and changes in arthritis: matrix degradation | |
| P478 | volume | 3 |
| Q35952166 | A New Application of Parallel Synthesis Strategy for Discovery of Amide-Linked Small Molecules as Potent Chondroprotective Agents in TNF-α-Stimulated Chondrocytes |
| Q51479947 | A comparison of cartilage stress-relaxation models in unconfined compression: QLV and stretched exponential in combination with fluid flow. |
| Q44733625 | A role for chemokines in the induction of chondrocyte phenotype modulation. |
| Q31134336 | Age-related changes in the proteoglycans of human skin. Specific cleavage of decorin to yield a major catabolic fragment in adult skin |
| Q24804310 | Aggrecanases and cartilage matrix degradation |
| Q37609322 | An in vitro model for the pathological degradation of articular cartilage in osteoarthritis |
| Q36736749 | An in vitro model of cartilage degradation by chondrocytes in a three-dimensional culture system |
| Q35102739 | Anti-Inflammatory mechanisms of the proteinase-activated receptor 2-inhibiting peptide in human synovial cells |
| Q37782019 | Cartilage biology, pathology, and repair. |
| Q46908223 | Cathepsins B, K, and L are regulated by a defined collagen type II peptide via activation of classical protein kinase C and p38 MAP kinase in articular chondrocytes |
| Q80275973 | Cellular and molecular responses in progressive pseudorheumatoid dysplasia articular cartilage associated with compound heterozygous WISP3 gene mutation |
| Q36281981 | Characterization of an exosite binding inhibitor of matrix metalloproteinase 13. |
| Q51518094 | Cyclic Tensile Strain Reduces TNF-α Induced Expression of MMP-13 by Condylar Temporomandibular Joint Cells. |
| Q35751704 | Detection of multiple autoantibodies in patients with ankylosing spondylitis using nucleic acid programmable protein arrays |
| Q30818159 | Distinct biological events generated by ECM proteolysis by two homologous collagenases |
| Q35553815 | Dual effects of 17beta-oestradiol on interleukin 1beta-induced proteoglycan degradation in chondrocytes |
| Q57813343 | Effects of multi-wall carbon nanotubes on structural and mechanical properties of poly(3-hydroxybutyrate)/chitosan electrospun scaffolds for cartilage tissue engineering |
| Q35844435 | FT-IR imaging of native and tissue-engineered bone and cartilage |
| Q36955365 | Fragmentation of decorin, biglycan, lumican and keratocan is elevated in degenerate human meniscus, knee and hip articular cartilages compared with age-matched macroscopically normal and control tissues |
| Q64947827 | IL-1β Damages Fibrocartilage and Upregulates MMP-13 Expression in Fibrochondrocytes in the Condyle of the Temporomandibular Joint. |
| Q55063229 | In vitro study on role of σB protein in avian reovirus pathogenesis. |
| Q35653934 | Intra-Articular Injections of Polyphenols Protect Articular Cartilage from Inflammation-Induced Degradation: Suggesting a Potential Role in Cartilage Therapeutics |
| Q38597565 | Investigational drugs for the treatment of osteoarthritis |
| Q35645792 | Involvement of ADAMTS5 and hyaluronidase in aggrecan degradation and release from OSM-stimulated cartilage |
| Q95269473 | Joint remodeling outcome of serum levels of Dickkopf-1 (DKK1), cartilage oligomeric matrix protein (COMP), and C-telopeptide of type II collagen (CTXII) in rheumatoid arthritis |
| Q36564656 | Laboratory Indicators of Aggrecan Turnover in Juvenile Idiopathic Arthritis. |
| Q39689896 | Lentiviral shRNA knock-down of ADAMTS-5 and -9 restores matrix deposition in 3D chondrocyte culture |
| Q47253483 | Leptin induces MMP1/13 and ADAMTS 4 expressions through bone morphogenetic protein-2 autocrine effect in human chondrocytes. |
| Q37147938 | Long-lasting tissue inflammatory processes trigger autoimmune responses to extracellular matrix molecules. |
| Q51140686 | Low-intensity ultrasound stimulation enhances chondrogenic differentiation in alginate culture of mesenchymal stem cells. |
| Q35553483 | Metalloproteinases, inflammation, and rheumatoid arthritis. |
| Q26865318 | Osteoarthritis pathogenesis: a review of molecular mechanisms |
| Q52996671 | Oxidative stress-induced apoptosis and matrix loss of chondrocytes is inhibited by eicosapentaenoic acid. |
| Q64068641 | Peptide Cross-Linked Poly (Ethylene Glycol) Hydrogel Films as Biosensor Coatings for the Detection of Collagenase |
| Q48246204 | Protective Effects of Garlic-Derived S-Allylmercaptocysteine on IL-1β-Stimulated Chondrocytes by Regulation of MMPs/TIMP-1 Ratio and Type II Collagen Expression via Suppression of NF-κB Pathway. |
| Q35683064 | Regulation of MMP-3 expression and secretion by the chemokine eotaxin-1 in human chondrocytes |
| Q51122126 | Release of transgenic progranulin from a living hyaline cartilage graft model: An in vitro evaluation on anti-inflammation. |
| Q34134566 | Serological biomarkers of joint tissue turnover predict tocilizumab response at baseline |
| Q39068431 | The Interface of Mechanics and Nociception in Joint Pathophysiology: Insights From the Facet and Temporomandibular Joints. |
| Q89967540 | The Secretome Derived From Mesenchymal Stromal Cells Cultured in a Xeno-Free Medium Promotes Human Cartilage Recovery in vitro |
| Q64082329 | The effects of laser acupuncture on the modulation of cartilage extracellular matrix macromolecules in rats with adjuvant-induced arthritis |
| Q28288792 | The role of human HtrA1 in arthritic disease |
| Q48871226 | Tough, Semisynthetic Hydrogels for Adipose Derived Stem Cell Delivery for Chondral Defect Repair. |
| Q58727377 | Zac1 regulates IL-11 expression in osteoarthritis |
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