| scholarly article | Q13442814 |
| review article | Q7318358 |
| P50 | author | Steven L Jones | Q88065350 |
| P2093 | author name string | Tatyana M Svitkina | |
| P2860 | cites work | betaIV spectrin, a new spectrin localized at axon initial segments and nodes of ranvier in the central and peripheral nervous system | Q24290541 |
| Spectrin and ankyrin-based pathways: metazoan inventions for integrating cells into tissues | Q24291372 | ||
| Neurofilament deficiency in quail caused by nonsense mutation in neurofilament-L gene | Q42194068 | ||
| A NOMPC-dependent membrane-microtubule connector is a candidate for the gating spring in fly mechanoreceptors. | Q42594952 | ||
| A critical role for Neurofascin in regulating action potential initiation through maintenance of the axon initial segment | Q42687432 | ||
| The node of Ranvier in the central nervous system | Q43653035 | ||
| Functional specialization of the axon initial segment by isoform-specific sodium channel targeting. | Q44376585 | ||
| Distinct contributions of Na(v)1.6 and Na(v)1.2 in action potential initiation and backpropagation. | Q45919318 | ||
| A selective filter for cytoplasmic transport at the axon initial segment | Q46096953 | ||
| Neurofilament distribution and organization in the myelinated axons of the peripheral nervous system. | Q48140740 | ||
| A targeting motif involved in sodium channel clustering at the axonal initial segment | Q48269160 | ||
| Accumulation of anchored proteins forms membrane diffusion barriers during neuronal polarization. | Q48274256 | ||
| Mixed microtubules steer dynein-driven cargo transport into dendrites | Q48317864 | ||
| Visualization of microtubule growth in cultured neurons via the use of EB3-GFP (end-binding protein 3-green fluorescent protein). | Q48342203 | ||
| Actin has a molecular scaffolding, not propulsive, role in presynaptic function | Q48405526 | ||
| Cooperative Interactions between 480 kDa Ankyrin-G and EB Proteins Assemble the Axon Initial Segment. | Q48618612 | ||
| MAP2 is localized to the dendrites of hippocampal neurons which develop in culture | Q48685423 | ||
| End binding protein-1 (EB1) complements microtubule-associated protein-1B during axonogenesis | Q48955330 | ||
| STED nanoscopy reveals the ubiquity of subcortical cytoskeleton periodicity in living neurons | Q50598032 | ||
| Increase in diameter of the axonal initial segment is an early change in amyotrophic lateral sclerosis | Q50792006 | ||
| Casein kinase 2 and microtubules control axon initial segment formation. | Q51899645 | ||
| Targeting of the F-actin-binding protein drebrin by the microtubule plus-tip protein EB3 is required for neuritogenesis. | Q51948942 | ||
| New role of IKK alpha/beta phosphorylated I kappa B alpha in axon outgrowth and axon initial segment development. | Q51962634 | ||
| A diffusion barrier maintains distribution of membrane proteins in polarized neurons. | Q52534153 | ||
| Nanoscale Architecture of the Axon Initial Segment Reveals an Organized and Robust Scaffold. | Q53228479 | ||
| miR-342-5p decreases ankyrin G levels in Alzheimer's disease transgenic mouse models. | Q53460335 | ||
| The ultrastructure of the nodes of Ranvier in cat sympathetic nerve fibers. | Q55037394 | ||
| Axonal site of spike initiation enhances auditory coincidence detection | Q59054940 | ||
| Muscarinic suppression of a novel voltage-sensitive K+ current in a vertebrate neurone | Q59066538 | ||
| Structure of the peripheral domains of neurofilaments revealed by low angle rotary shadowing | Q67936243 | ||
| The structure, biochemical properties, and immunogenicity of neurofilament peripheral regions are determined by phosphorylation state | Q69955055 | ||
| Observations on the ultrastructure of the axon hillock and initial axon segment of lumbosacral motoneurons in the cat | Q71336371 | ||
| Neuronal polarity | Q72533846 | ||
| Regional modulation of neurofilament organization by myelination in normal axons | Q72816493 | ||
| Spectrin (betaSpIIsigma1) is an essential component of synaptic transmission | Q73416448 | ||
| The role of selective transport in neuronal protein sorting | Q73853663 | ||
| EB1 identifies sites of microtubule polymerisation during neurite development | Q77612615 | ||
| Ankyrins | Q77932251 | ||
| BetaIV spectrins are essential for membrane stability and the molecular organization of nodes of Ranvier | Q80467956 | ||
| Dynein Regulator NDEL1 Controls Polarized Cargo Transport at the Axon Initial Segment | Q87227789 | ||
| Modulation of the dynamic instability of tubulin assembly by the microtubule-associated protein tau | Q24294296 | ||
| Crystal structure and functional interpretation of the erythrocyte spectrin tetramerization domain complex | Q24301548 | ||
| A common ankyrin-G-based mechanism retains KCNQ and NaV channels at electrically active domains of the axon | Q24307090 | ||
| AnkyrinG. A new ankyrin gene with neural-specific isoforms localized at the axonal initial segment and node of Ranvier | Q24311821 | ||
| Dynamic microtubules regulate dendritic spine morphology and synaptic plasticity | Q24316951 | ||
| Electrogenic tuning of the axon initial segment | Q24634301 | ||
| [Beta]IV-spectrin regulates sodium channel clustering through ankyrin-G at axon initial segments and nodes of Ranvier | Q24652657 | ||
| The phosphorylation state of the FIGQY tyrosine of neurofascin determines ankyrin-binding activity and patterns of cell segregation | Q24657641 | ||
| AnkyrinG is required for clustering of voltage-gated Na channels at axon initial segments and for normal action potential firing | Q24682474 | ||
| Neurofascin assembles a specialized extracellular matrix at the axon initial segment | Q24682746 | ||
| Ankyrin-G coordinates assembly of the spectrin-based membrane skeleton, voltage-gated sodium channels, and L1 CAMs at Purkinje neuron initial segments | Q24685343 | ||
| Axon initial segments: diverse and dynamic neuronal compartments | Q27025814 | ||
| Localization and Structure of the Ankyrin-binding Site on 2-Spectrin | Q27653198 | ||
| Structures of the spectrin-ankyrin interaction binding domains | Q27653418 | ||
| The structure of the ankyrin-binding site of -spectrin reveals how tandem spectrin-repeats generate unique ligand-binding properties | Q27653516 | ||
| betaIV-spectrin forms a diffusion barrier against L1CAM at the axon initial segment | Q27865184 | ||
| Purification and characterization of an alpha 1 beta 2 isoform of CapZ from human erythrocytes: cytosolic location and inability to bind to Mg2+ ghosts suggest that erythrocyte actin filaments are capped by adducin | Q28253307 | ||
| Ankyrin binds to the 15th repetitive unit of erythroid and nonerythroid beta-spectrin | Q28272341 | ||
| Ankyrin-based subcellular gradient of neurofascin, an immunoglobulin family protein, directs GABAergic innervation at purkinje axon initial segment | Q28287481 | ||
| The cytoskeletal and signaling mechanisms of axon collateral branching | Q28305090 | ||
| Delayed maturation of regenerating myelinated axons in mice lacking neurofilaments | Q28506520 | ||
| Specific role of the truncated betaIV-spectrin Sigma6 in sodium channel clustering at axon initial segments and nodes of ranvier | Q28508871 | ||
| Restriction of 480/270-kD ankyrin G to axon proximal segments requires multiple ankyrin G-specific domains | Q28566467 | ||
| End-binding proteins EB3 and EB1 link microtubules to ankyrin G in the axon initial segment | Q28580184 | ||
| Neurofilament-deficient axons and perikaryal aggregates in viable transgenic mice expressing a neurofilament-beta-galactosidase fusion protein | Q28590518 | ||
| BetaIVSigma1 spectrin stabilizes the nodes of Ranvier and axon initial segments | Q28591439 | ||
| TRIM46 Controls Neuronal Polarity and Axon Specification by Driving the Formation of Parallel Microtubule Arrays | Q28771492 | ||
| Microtubules have opposite orientation in axons and dendrites of Drosophila neurons | Q30483775 | ||
| The axon hillock and the initial segment | Q30494627 | ||
| Myosin-dependent targeting of transmembrane proteins to neuronal dendrites | Q30496554 | ||
| The actin nucleating Arp2/3 complex contributes to the formation of axonal filopodia and branches through the regulation of actin patch precursors to filopodia | Q30503395 | ||
| MAP1B regulates microtubule dynamics by sequestering EB1/3 in the cytosol of developing neuronal cells | Q30539497 | ||
| In vivo assembly of the axon initial segment in motor neurons | Q30581713 | ||
| Polarity orientation of microtubules in hippocampal neurons: uniformity in the axon and nonuniformity in the dendrite | Q33666684 | ||
| A role for myosin VI in the localization of axonal proteins. | Q33842193 | ||
| Characterization of the axon initial segment (AIS) of motor neurons and identification of a para-AIS and a juxtapara-AIS, organized by protein 4.1B. | Q34035130 | ||
| Pleckstrin homology domains and the cytoskeleton | Q34120310 | ||
| Identification of a Conserved Ankyrin-binding Motif in the Family of Sodium Channel α Subunits | Q34193048 | ||
| Ankyrin G restricts ion channel diffusion at the axonal initial segment before the establishment of the diffusion barrier | Q34218857 | ||
| Purification of tau, a microtubule-associated protein that induces assembly of microtubules from purified tubulin | Q34243042 | ||
| Actin, spectrin, and associated proteins form a periodic cytoskeletal structure in axons | Q34317568 | ||
| Action potential generation requires a high sodium channel density in the axon initial segment | Q34587263 | ||
| Actin cytoskeleton regulation in neuronal morphogenesis and structural plasticity | Q34762533 | ||
| Giant ankyrin-G: a critical innovation in vertebrate evolution of fast and integrated neuronal signaling | Q35038044 | ||
| Developmental mechanism of the periodic membrane skeleton in axons | Q35111250 | ||
| Piccolo regulates the dynamic assembly of presynaptic F-actin | Q35533808 | ||
| A novel recessive Nefl mutation causes a severe, early-onset axonal neuropathy | Q35629933 | ||
| The role of microtubule-associated protein 2 (MAP-2) in neuronal growth, plasticity, and degeneration | Q35658487 | ||
| Ankyrins. Adaptors between diverse plasma membrane proteins and the cytoplasm | Q35874056 | ||
| Molecular mechanisms for organizing the neuronal cytoskeleton. | Q35880065 | ||
| A distal axonal cytoskeleton forms an intra-axonal boundary that controls axon initial segment assembly. | Q35992656 | ||
| β-III spectrin is critical for development of purkinje cell dendritic tree and spine morphogenesis | Q36031082 | ||
| Molecular motors and mechanisms of directional transport in neurons | Q36042285 | ||
| Axons break in animals lacking beta-spectrin | Q36117723 | ||
| betaIV spectrin is recruited to axon initial segments and nodes of Ranvier by ankyrinG. | Q36117801 | ||
| Differential trafficking of transport vesicles contributes to the localization of dendritic proteins | Q36128474 | ||
| The small pyramidal neuron of the rat cerebral cortex. The axon hillock and initial segment | Q36190081 | ||
| Organization of mammalian neurofilament polypeptides within the neuronal cytoskeleton | Q36210648 | ||
| Brain spectrin(240/235) and brain spectrin(240/235E): two distinct spectrin subtypes with different locations within mammalian neural cells | Q36215178 | ||
| Visualization of the hexagonal lattice in the erythrocyte membrane skeleton | Q36216490 | ||
| Synapsin I-mediated interaction of brain spectrin with synaptic vesicles. | Q36530019 | ||
| Networks of polarized actin filaments in the axon initial segment provide a mechanism for sorting axonal and dendritic proteins. | Q36872581 | ||
| AnkyrinG is required for maintenance of the axon initial segment and neuronal polarity. | Q36972640 | ||
| Microtubules in dendritic spine development | Q37019342 | ||
| Postsynaptic density-93 clusters Kv1 channels at axon initial segments independently of Caspr2. | Q37311277 | ||
| AnkyrinG is required to maintain axo-dendritic polarity in vivo | Q37394946 | ||
| Establishment of axon-dendrite polarity in developing neurons. | Q37463169 | ||
| Visualization of the protein associations in the erythrocyte membrane skeleton | Q37542045 | ||
| Axon initial segment cytoskeleton comprises a multiprotein submembranous coat containing sparse actin filaments | Q37703484 | ||
| Membrane domains based on ankyrin and spectrin associated with cell-cell interactions | Q37748235 | ||
| The axon initial segment and the maintenance of neuronal polarity. | Q37772757 | ||
| The spectrin-ankyrin-4.1-adducin membrane skeleton: adapting eukaryotic cells to the demands of animal life | Q37776425 | ||
| Which way to go? Cytoskeletal organization and polarized transport in neurons | Q37785317 | ||
| Determinants of voltage-gated sodium channel clustering in neurons. | Q37799104 | ||
| The axon initial segment in nervous system disease and injury | Q37958904 | ||
| Signal processing in the axon initial segment | Q37979364 | ||
| The physiology of the axon initial segment | Q37996472 | ||
| The axon as a unique computational unit in neurons | Q38072500 | ||
| No Pasaran! Role of the axon initial segment in the regulation of protein transport and the maintenance of axonal identity. | Q38163250 | ||
| The Nodes of Ranvier: Molecular Assembly and Maintenance | Q38583864 | ||
| The ins and outs of polarized axonal domains. | Q38632821 | ||
| Activity-dependent relocation of the axon initial segment fine-tunes neuronal excitability | Q38751797 | ||
| Role of the Tau N-terminal region in microtubule stabilization revealed by new endogenous truncated forms | Q38874926 | ||
| Cysteine 70 of ankyrin-G is S-palmitoylated and is required for function of ankyrin-G in membrane domain assembly | Q39248845 | ||
| The human erythrocyte plasma membrane: a Rosetta Stone for decoding membrane-cytoskeleton structure | Q39305475 | ||
| Novel diffusion barrier for axonal retention of Tau in neurons and its failure in neurodegeneration | Q39938642 | ||
| A functional barrier to movement of lipids in polarized neurons | Q41097297 | ||
| Cell surface organization by the membrane skeleton. | Q41099752 | ||
| MAP2 and tau segregate into dendritic and axonal domains after the elaboration of morphologically distinct neurites: an immunocytochemical study of cultured rat cerebrum | Q41250929 | ||
| Projection domains of MAP2 and tau determine spacings between microtubules in dendrites and axons | Q41589236 | ||
| Microtubules provide directional cues for polarized axonal transport through interaction with kinesin motor head | Q42090943 | ||
| Plasticity at the axon initial segment | Q42128808 | ||
| P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | cytoskeleton | Q154626 |
| cell polarity | Q189100 | ||
| nervous system | Q9404 | ||
| cell | Q7868 | ||
| P304 | page(s) | 6808293 | |
| P577 | publication date | 2016-07-17 | |
| P1433 | published in | Neural Plasticity | Q15716605 |
| P1476 | title | Axon Initial Segment Cytoskeleton: Architecture, Development, and Role in Neuron Polarity | |
| P478 | volume | 2016 |
| Q42546825 | Altered axon initial segment in hippocampal newborn neurons, associated with recurrence of temporal lobe epilepsy in rats |
| Q59808645 | An Integrated Cytoskeletal Model of Neurite Outgrowth |
| Q50985246 | Axodendritic sorting and pathological missorting of Tau are isoform-specific and determined by axon initial segment architecture |
| Q55272773 | Axon outgrowth and neuronal differentiation defects after a-SMN and FL-SMN silencing in primary hippocampal cultures. |
| Q33650497 | Axonal Membranes and Their Domains: Assembly and Function of the Axon Initial Segment and Node of Ranvier |
| Q41440551 | Bar-coding neurodegeneration: identifying subcellular effects of human neurodegenerative disease proteins using Drosophila leg neurons. |
| Q58698855 | Cell cycle reentry triggers hyperploidization and synaptic dysfunction followed by delayed cell death in differentiated cortical neurons |
| Q52311291 | Cellular Plasticity in the Adult Murine Piriform Cortex: Continuous Maturation of Dormant Precursors Into Excitatory Neurons. |
| Q92616383 | Changes in the Fluorescence Tracking of NaV1.6 Protein Expression in a BTBR T+Itpr3tf/J Autistic Mouse Model |
| Q47862542 | Critical roles of αII spectrin in brain development and epileptic encephalopathy. |
| Q58752900 | Functional differences of short and long isoforms of spastin harboring missense mutation |
| Q90162261 | Imaging of the Axon Initial Segment |
| Q90375185 | Neuropathic Pain Creates an Enduring Prefrontal Cortex Dysfunction Corrected by the Type II Diabetic Drug Metformin But Not by Gabapentin |
| Q93213308 | Pharmacophore-based models for therapeutic drugs against phosphorylated tau in Alzheimer's disease |
| Q48090878 | Regulation of plasma membrane expansion during axon formation. |
| Q63359408 | TRIM46 organizes microtubule fasciculation in the axon initial segment |
| Q39292465 | The Segregated Expression of Voltage-Gated Potassium and Sodium Channels in Neuronal Membranes: Functional Implications and Regulatory Mechanisms |
| Q47706322 | The axon initial segment: an updated viewpoint |
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