| scholarly article | Q13442814 |
| review article | Q7318358 |
| P50 | author | Geert Hamer | Q51733951 |
| Ans van Pelt | Q59784000 | ||
| Yi Zheng | Q86820272 | ||
| P2093 | author name string | Sjoerd Repping | |
| Robert B Struijk | |||
| Sabrina Z Jan | |||
| Callista L Mulder | |||
| P2860 | cites work | Biotechnology. A prudent path forward for genomic engineering and germline gene modification | Q22065510 |
| Don’t edit the human germ line | Q22122315 | ||
| CRISPR/Cas9-mediated gene editing in human tripronuclear zygotes | Q22337358 | ||
| An operational definition of epigenetics | Q24568002 | ||
| RNA-guided human genome engineering via Cas9 | Q24598394 | ||
| Cpf1 is a single RNA-guided endonuclease of a class 2 CRISPR-Cas system | Q24669821 | ||
| Experimental methods to preserve male fertility and treat male factor infertility | Q26770116 | ||
| Assisted reproductive technology and birth defects: a systematic review and meta-analysis | Q26859203 | ||
| Epigenome engineering in cancer: fairytale or a realistic path to the clinic? | Q26861350 | ||
| Spermatogonial stem cells from domestic animals: progress and prospects | Q27021986 | ||
| Spermatogonial stem cell niche and spermatogonial stem cell transplantation in zebrafish | Q27319999 | ||
| Persistent epigenetic differences associated with prenatal exposure to famine in humans | Q28298905 | ||
| Functional repair of CFTR by CRISPR/Cas9 in intestinal stem cell organoids of cystic fibrosis patients | Q28303521 | ||
| A genome-wide association study in Chinese men identifies three risk loci for non-obstructive azoospermia | Q28943316 | ||
| One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering | Q29547524 | ||
| Cancer epigenetics: from mechanism to therapy | Q29614799 | ||
| CRISPR-Cas systems for editing, regulating and targeting genomes | Q29615781 | ||
| Genome-scale CRISPR-Cas9 knockout screening in human cells | Q29616044 | ||
| High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells | Q29616045 | ||
| Spermatogonial stem cell transplantation into rhesus testes regenerates spermatogenesis producing functional sperm. | Q30536417 | ||
| Semen analysis data from fresh and cryopreserved donor ejaculates: comparison of cryoprotectants and pregnancy rates | Q31116347 | ||
| The genetic basis of male reproductive failure | Q33329350 | ||
| Testicular tissue cryopreservation and spermatogonial stem cell transplantation to restore fertility: from bench to bedside | Q33752488 | ||
| Spermatogonial stem cells derived from infertile Wv/Wv mice self-renew in vitro and generate progeny following transplantation | Q33770650 | ||
| Copy number variants in patients with severe oligozoospermia and Sertoli-cell-only syndrome. | Q33894894 | ||
| Birth of a normal girl after in vitro fertilization and preimplantation diagnostic testing for cystic fibrosis | Q33970561 | ||
| Transgenerational effects of prenatal exposure to the Dutch famine on neonatal adiposity and health in later life | Q34013431 | ||
| The effect of patient and semen characteristics on live birth rates following intrauterine insemination: a retrospective study | Q34025107 | ||
| Genome editing with Cas9 in adult mice corrects a disease mutation and phenotype. | Q34040385 | ||
| Epigenome editing by a CRISPR-Cas9-based acetyltransferase activates genes from promoters and enhancers. | Q34043681 | ||
| Genome-wide inactivation of porcine endogenous retroviruses (PERVs). | Q34045122 | ||
| Rationally engineered Cas9 nucleases with improved specificity | Q34045530 | ||
| Conservation of spermatogonial stem cell self-renewal signaling between mouse and rat. | Q34063664 | ||
| Evaluation and treatment of male infertility | Q34095206 | ||
| Evaluation of 172 candidate polymorphisms for association with oligozoospermia or azoospermia in a large cohort of men of European descent | Q34109272 | ||
| Seamless gene correction of β-thalassemia mutations in patient-specific iPSCs using CRISPR/Cas9 and piggyBac | Q34153816 | ||
| Understanding transgenerational epigenetic inheritance via the gametes in mammals | Q34250734 | ||
| Chromatin replication and epigenome maintenance | Q34256428 | ||
| Restoring fertility in sterile childhood cancer survivors by autotransplanting spermatogonial stem cells: are we there yet? | Q34333957 | ||
| Growth factors essential for self-renewal and expansion of mouse spermatogonial stem cells | Q34364153 | ||
| Induced DNA demethylation by targeting Ten-Eleven Translocation 2 to the human ICAM-1 promoter | Q34382768 | ||
| Propagation of human germ stem cells in long-term culture | Q34410680 | ||
| Prevention of muscular dystrophy in mice by CRISPR/Cas9-mediated editing of germline DNA | Q34433586 | ||
| Environmental epigenetic inheritance through gametes and implications for human reproduction | Q34449024 | ||
| Correction of a genetic disease by CRISPR-Cas9-mediated gene editing in mouse spermatogonial stem cells | Q34452056 | ||
| Expansion and long-term culture of human spermatogonial stem cells via the activation of SMAD3 and AKT pathways | Q34481338 | ||
| Sex-specific, male-line transgenerational responses in humans | Q34481537 | ||
| Molecular control of rodent spermatogenesis | Q37988312 | ||
| From in vitro culture to in vivo models to study testis development and spermatogenesis | Q38030382 | ||
| Spermatogonial stem cell preservation and transplantation: from research to clinic | Q38083264 | ||
| Genetic testing and counselling for male infertility | Q38205077 | ||
| Current and future delivery systems for engineered nucleases: ZFN, TALEN and RGEN. | Q38305620 | ||
| Transgenerational effects of prenatal exposure to the 1944-45 Dutch famine. | Q38427958 | ||
| Germline genome-editing research and its socioethical implications | Q38528724 | ||
| How successful is TESE-ICSI in couples with non-obstructive azoospermia? | Q38530042 | ||
| Review and follow-up of patients using a regional sperm cryopreservation service: ensuring that resources are targeted to those patients most in need | Q38530560 | ||
| A European perspective on testicular tissue cryopreservation for fertility preservation in prepubertal and adolescent boys | Q38584517 | ||
| Genome engineering through CRISPR/Cas9 technology in the human germline and pluripotent stem cells | Q38757108 | ||
| AZFc deletions do not affect the function of human spermatogonia in vitro. | Q38883684 | ||
| Genome editing of the germline: broadening the discussion | Q39001539 | ||
| Aberrant DNA methylation patterns of spermatozoa in men with unexplained infertility. | Q39031237 | ||
| Genetic and epigenetic stability of human spermatogonial stem cells during long-term culture | Q39123095 | ||
| Perspectives of infertile men on future stem cell treatments for nonobstructive azoospermia | Q39225463 | ||
| A combined approach facilitates the reliable detection of human spermatogonia in vitro. | Q39356360 | ||
| DNA methylation in spermatozoa as a prospective marker in andrology | Q39362648 | ||
| Vitrification preserves proliferation capacity in human spermatogonia | Q39486258 | ||
| In search of an efficient injection technique for future clinical application of spermatogonial stem cell transplantation: infusion of contrast dyes in isolated cadaveric human testes | Q39552354 | ||
| Production of zebrafish offspring from cultured spermatogonial stem cells | Q39644867 | ||
| Generation of mice by transplantation of an adult spermatogonial cell line after cryopreservation. | Q39868844 | ||
| Heritable imprinting defect caused by epigenetic abnormalities in mouse spermatogonial stem cells | Q39914563 | ||
| Long-term culture of male germline stem cells from hamster testes | Q40032920 | ||
| Long-term spermatogonial survival in cryopreserved and xenografted immature human testicular tissue | Q40065360 | ||
| Spermatogonial survival after cryopreservation and short-term orthotopic immature human cryptorchid testicular tissue grafting to immunodeficient mice | Q40215865 | ||
| Fertility and germline transmission of donor haplotype following germ cell transplantation in immunocompetent goats. | Q40581987 | ||
| Long-Term Proliferation in Culture and Germline Transmission of Mouse Male Germline Stem Cells1 | Q40654689 | ||
| Preimplantation diagnosis for Huntington's disease (HD): clinical application and analysis of the HD expansion in affected embryos. | Q40974688 | ||
| Analysis of DNA damage after human sperm cryopreservation in genes crucial for fertilization and early embryo development | Q41603973 | ||
| What is the best cryopreservation protocol for human testicular tissue banking? | Q41604518 | ||
| Can prepubertal human testicular tissue be cryopreserved by vitrification? | Q41608236 | ||
| Precise correction of the dystrophin gene in duchenne muscular dystrophy patient induced pluripotent stem cells by TALEN and CRISPR-Cas9. | Q41873090 | ||
| Testicular recovery after irradiation differs in prepubertal and pubertal non-human primates, and can be enhanced by autologous germ cell transplantation | Q41890288 | ||
| Genome Editing in Mouse Spermatogonial Stem Cell Lines Using TALEN and Double-Nicking CRISPR/Cas9. | Q42070255 | ||
| Epimutations in Prader-Willi and Angelman syndromes: a molecular study of 136 patients with an imprinting defect | Q42156745 | ||
| Optimizing cryopreservation of human testicular tissue: comparison of protocols with glycerol, propanediol and dimethylsulphoxide as cryoprotectants | Q42477538 | ||
| Dynamics of 5-hydroxymethylcytosine during mouse spermatogenesis. | Q42773820 | ||
| Chromatin and transcription transitions of mammalian adult germline stem cells and spermatogenesis. | Q42775057 | ||
| Germ cell transplantation in pigs | Q43829229 | ||
| Efficient generation of transgenic rats through the male germline using lentiviral transduction and transplantation of spermatogonial stem cells. | Q44076350 | ||
| DNA methylation patterns of spermatozoa and two generations of offspring obtained after murine spermatogonial stem cell transplantation | Q44147096 | ||
| Long-term survival of human spermatogonial stem cells in mouse testes | Q44245848 | ||
| Array comparative genomic hybridization analysis does not show genetic alterations in spermatozoa and offspring generated after spermatogonial stem cell transplantation in the mouse | Q44555166 | ||
| Germline gene therapy: We're ready | Q45877003 | ||
| Genetic selection of mouse male germline stem cells in vitro: offspring from single stem cells | Q45878466 | ||
| High-fidelity CRISPR-Cas9 nucleases with no detectable genome-wide off-target effects. | Q34507554 | ||
| Genome editing in mouse spermatogonial stem/progenitor cells using engineered nucleases | Q34542214 | ||
| Spermatogonial stem cell preservation and transplantation. | Q34623404 | ||
| Correction of a genetic disease in mouse via use of CRISPR-Cas9. | Q34658184 | ||
| Epigenetics and cardiovascular disease | Q34788746 | ||
| In Search of Better Spermatogonial Preservation by Supplementation of Cryopreserved Human Immature Testicular Tissue Xenografts with N-acetylcysteine and Testosterone | Q34867930 | ||
| Improved vectors and genome-wide libraries for CRISPR screening | Q35215629 | ||
| Targeted Germline Modifications in Rats Using CRISPR/Cas9 and Spermatogonial Stem Cells | Q35224542 | ||
| Separating spermatogonia from cancer cells in contaminated prepubertal primate testis cell suspensions. | Q35540570 | ||
| Perinatal outcome of singletons and twins after assisted conception: a systematic review of controlled studies | Q35629303 | ||
| Generation of fertile offspring from Kit(w)/Kit(wv) mice through differentiation of gene corrected nuclear transfer embryonic stem cells | Q35823820 | ||
| Fertile offspring derived from mouse spermatogonial stem cells cryopreserved for more than 14 years | Q35896533 | ||
| Spermatogenesis following male germ-cell transplantation | Q35907473 | ||
| Beyond the mouse monopoly: studying the male germ line in domestic animal models | Q35974786 | ||
| The genetics of human infertility by functional interrogation of SNPs in mice | Q35989784 | ||
| Non-viral transfection of goat germline stem cells by nucleofection results in production of transgenic sperm after germ cell transplantation | Q36012811 | ||
| Spermatogenesis after cancer treatment: damage and recovery | Q36077596 | ||
| Birth of healthy children after preimplantation diagnosis of thalassemias. | Q36271692 | ||
| Crystal Structure of Staphylococcus aureus Cas9 | Q36348284 | ||
| Clinical potential and putative risks of fertility preservation in children utilizing gonadal tissue or germline stem cells | Q36426335 | ||
| Epigenetic Editing: targeted rewriting of epigenetic marks to modulate expression of selected target genes | Q36435079 | ||
| The human Y chromosome: a masculine chromosome | Q36464874 | ||
| Male germline stem cells: from mice to men. | Q36796603 | ||
| Introducing precise genetic modifications into human 3PN embryos by CRISPR/Cas-mediated genome editing | Q36910225 | ||
| Effects of chemotherapy and radiotherapy on spermatogenesis in humans | Q37305907 | ||
| Epigenetic regulation of the RHOX homeobox gene cluster and its association with human male infertility | Q37380149 | ||
| Testicular stem cells for fertility preservation: preclinical studies on male germ cell transplantation and testicular grafting. | Q37470404 | ||
| An experimental protocol for fertility preservation in prepubertal boys recently diagnosed with cancer: a report of acceptability and safety | Q37479062 | ||
| Epigenetics: deciphering how environmental factors may modify autoimmune type 1 diabetes | Q37583646 | ||
| Unravelling the genetics of spermatogenic failure | Q37602410 | ||
| Short and long-term risks to women who conceive through in vitro fertilization | Q37636087 | ||
| The histone methyltransferase ESET is required for the survival of spermatogonial stem/progenitor cells in mice | Q37726170 | ||
| Testicular function and fertility preservation in male cancer patients | Q37852326 | ||
| Decreased birthweights in infants after maternal in utero exposure to the Dutch famine of 1944-1945 | Q46368071 | ||
| Cryopreservation of intact testicular tissue from boys with cryptorchidism. | Q46739992 | ||
| Irradiated mouse testes efficiently support spermatogenesis derived from donor germ cells of mice and rats | Q46843943 | ||
| Irradiation enhances the efficiency of testicular germ cell transplantation in sheep | Q47634346 | ||
| Germline epimutation of MLH1 in individuals with multiple cancers | Q47817335 | ||
| Sperm banking and rate of assisted reproduction treatment: insights from a 15-year cryopreservation program for male cancer patients | Q48015312 | ||
| The AZFc region of the Y chromosome features massive palindromes and uniform recurrent deletions in infertile men. | Q48335216 | ||
| International Committee for Monitoring Assisted Reproductive Technology (ICMART) and the World Health Organization (WHO) revised glossary of ART terminology, 2009. | Q48667199 | ||
| Distinction between early and late ovarian hyperstimulation syndrome | Q48891954 | ||
| PRM1 variant rs35576928 (Arg>Ser) is associated with defective spermatogenesis in the Chinese Han population | Q49063382 | ||
| Eliminating acute lymphoblastic leukemia cells from human testicular cell cultures: a pilot study. | Q50478205 | ||
| Computer assisted image analysis to assess colonization of recipient seminiferous tubules by spermatogonial stem cells from transgenic donor mice. | Q50518779 | ||
| Germ cell transfer into rat, bovine, monkey and human testes. | Q51193066 | ||
| Long-term culture of mouse male germline stem cells under serum-or feeder-free conditions. | Q51566448 | ||
| Management of fertility preservation in prepubertal patients: 5 years' experience at the Catholic University of Louvain. | Q51733282 | ||
| Eugenics lurk in the shadow of CRISPR. | Q52423681 | ||
| Methods of cryopreservation of testicular tissue with viable spermatogonia in pre-pubertal boys undergoing gonadotoxic cancer treatment. | Q53574529 | ||
| Analysis of 6 single-nucleotide polymorphisms in the androgen receptor gene in Chilean patients with primary spermatogenic failure. | Q54383678 | ||
| Propagation of human spermatogonial stem cells in vitro. | Q54454106 | ||
| The sensitivity to X rays of mouse spermatogonia that are committed to differentiate and of differentiating spermatogonia | Q57280399 | ||
| The efficiency of magnetic-activated cell sorting and fluorescence-activated cell sorting in the decontamination of testicular cell suspensions in cancer patients | Q59164036 | ||
| In Vitro Propagation of Human Prepubertal Spermatogonial Stem Cells | Q59782798 | ||
| A single-nucleotide polymorphism of the DAZL gene promoter confers susceptibility to spermatogenic failure in the Taiwanese Han | Q60495953 | ||
| Morphometrical quantification of spermatogonial germ cells with the 57B anti-MAGE-A4 antibody in the evaluation of testicular biopsies for azoospermia | Q73063437 | ||
| Male infertility | Q73164655 | ||
| Transplantation of testis germinal cells into mouse seminiferous tubules | Q73165351 | ||
| Homing Efficiency and Proliferation Kinetics of Male Germ Line Stem Cells Following Transplantation in Mice1 | Q73282167 | ||
| Autologous and homologous transplantation of bovine spermatogonial stem cells | Q75352016 | ||
| Spermatogonial proliferation and apoptosis in hypospermatogenesis associated with nonobstructive azoospermia | Q77156777 | ||
| Men with infertility caused by AZFc deletion can produce sons by intracytoplasmic sperm injection, but are likely to transmit the deletion and infertility | Q77990548 | ||
| Pregnancy is predictable: a large-scale prospective external validation of the prediction of spontaneous pregnancy in subfertile couples | Q80335494 | ||
| Cryopreservation of human spermatozoa decreases the number of motile normal spermatozoa, induces nuclear vacuolization and chromatin decondensation | Q84382797 | ||
| Reduced numbers of Sertoli, germ, and spermatogonial stem cells in impaired spermatogenesis | Q84391919 | ||
| Long-term proliferation and characterization of human spermatogonial stem cells obtained from obstructive and non-obstructive azoospermia under exogenous feeder-free culture conditions | Q84507467 | ||
| Idiopathic male infertility is strongly associated with aberrant methylation of MEST and IGF2/H19 ICR1 | Q84822876 | ||
| Efficient intracellular delivery of native proteins | Q87181880 | ||
| A genome-wide DNA methylation study in azoospermia | Q87345596 | ||
| P275 | copyright license | Creative Commons Attribution-NonCommercial 4.0 International | Q34179348 |
| P433 | issue | 5 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | male infertility | Q280156 |
| autotransplantation | Q379071 | ||
| genitourinary system | Q4712977 | ||
| cell | Q7868 | ||
| gene editing | Q65363531 | ||
| biomedical investigative technique | Q66648976 | ||
| P5008 | on focus list of Wikimedia project | ScienceSource | Q55439927 |
| P304 | page(s) | 561-573 | |
| P577 | publication date | 2016-05-30 | |
| 2016-09-01 | |||
| P1433 | published in | Human Reproduction Update | Q15724523 |
| P1476 | title | Spermatogonial stem cell autotransplantation and germline genomic editing: a future cure for spermatogenic failure and prevention of transmission of genomic diseases | |
| P478 | volume | 22 |
| Q45872166 | Biological therapy for non-obstructive azoospermia |
| Q47205272 | Dynamics, ultrastructure and gene expression of human in-vitro organized testis cells from testicular sperm extraction biopsies |
| Q92065207 | Establishment of cell lines with porcine spermatogonial stem cell properties |
| Q90463773 | Fertility Preservation in Male to Female Transgender Patients |
| Q55261311 | Framing the ethical and legal issues of human artificial gametes in research, therapy, and assisted reproduction: A German perspective. |
| Q57473265 | Human testis extracellular matrix enhances human spermatogonial stem cell survival in vitro |
| Q54994355 | Isolation and Proliferation of Spermatogonial Cells from Ghezel Sheep. |
| Q38687509 | Long-Term Propagation of Porcine Undifferentiated Spermatogonia |
| Q47374056 | Long-term health in recipients of transplanted in vitro propagated spermatogonial stem cells |
| Q92796969 | Manipulation of spermatogonial stem cells in livestock species |
| Q92091743 | PAMAM-cRGD mediating efficient siRNA delivery to spermatogonial stem cells |
| Q100425535 | Personalized Medicine for the Infertile Male |
| Q47638118 | Phospholipase D Family Member 6 Is a Surface Marker for Enrichment of Undifferentiated Spermatogonia in Prepubertal Boars |
| Q91749619 | Stem Cells as a Resource for Treatment of Infertility-related Diseases |
| Q58760598 | The Safe Recipient of SSC Transplantation Prepared by Heat Shock With Busulfan Treatment in Mice |
| Q57164120 | The ethics of clinical applications of germline genome modification: a systematic review of reasons |
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